Medicine and Health Sciences Commons^™

Breaking Down The Impact Of Resilience On Mental Health: An Analysis Utilizing The Resilience Scale For Adults, Sydney K. Cook

The Journal of Purdue Undergraduate Research

Resilience is the capacity to recover quickly from difficulties, and previous studies have determined that resilience has a relationship with mental health. However, the association of each aspect of resilience on mental health, depression, and adverse childhood events (ACEs) have not been closely examined. Discerning which aspects of resilience are associated with mental health issues, depression, and ACEs can help psychiatric nurses determine effective treatments and interventions for at-risk patients.

One hundred ninety-five community-dwelling participants (ages 18 to 89) were invited to Purdue University in Indiana and Scripps College in California for the study. Participants completed the Resilience Scale for …

Purdue College Of Pharmacy's Response To The Hand Sanitizer Shortage During The Pandemic, Alissa M. Freimuth, Alicia S. Cheng, Rurie W. Lee, Nicole L. Noel, Trexie M. Rudd, Jane E. Krause

Purdue Journal of Service-Learning and International Engagement

With the outbreak of Coronavirus Disease 2019 (COVID-19), came struggles and hardships that were not foreseen. One of these struggles was to maintain an adequate supply of medical equipment, medications, and other necessities to help protect individuals and communities. Proper hand hygiene is an important part of the response to COVID-19. Sanitizing and taking steps to prevent contraction of COVID-19 was a high priority and with the high demand, the availability of hand sanitizer was scare.

In March 2020, the US Food and Drug Administration (FDA) released a policy allowing pharmacists to temporarily compound alcohol-based hand sanitizer during the public …

Homelessness And Covid-19, Justin Macneill, Alexa Lahey, Nina Teo

Purdue Journal of Service-Learning and International Engagement

The COVID-19 pandemic has exacerbated the struggle of people experiencing homelessness (PEH) and presented new challenges to those serving this vulnerable population. To better understand and articulate how COVID has impacted both PEH and their ecosystem of support, we compared the national response - aggregated via a literature review of both gray and academic literature - to the statewide response in Indiana and the local response in Tippecanoe County.

Local homelessness providers emphasized that organizational partnerships are key - policy changes in one organization can have malignant effect extending throughout and putting additional strain on other organizations within the local …

Service-Learning In The Virtual Space: Mixed Method Analysis Of Steps Pipeline Program, Katherine Ceglio, Julianne Stout

Purdue Journal of Service-Learning and International Engagement

North Central Indiana Area Health Education Center (NCI-AHEC) aims to develop the healthcare infrastructure by encouraging rural students to pursue healthcare professions. In light of rural healthcare shortages found in Indiana, they implemented a pipeline program, Successfully Training and Educating Pre-medical Students (STEPS). This program offers mentoring and educational assistance to pre-health-professional undergraduate students at Indiana University – Kokomo. During the COVID-19 pandemic, the Purdue research team partnered with NCI-AHEC to conduct a completely virtual mixed method study that examined the initial impact of the STEPS program and made recommendations for improvement.

The opportunities for virtual collaboration created during the …

From There To Here: Evaluating The Transition Of An International Advanced Pharmacy Practice Experience In London, Ishmum Hasan, Stephanie Hendricks, Michaela Todd, Grace Yun, Sotiris Antoniou, Monica Miller, Ellen Schellhase, Alexandra Van-Slageren

Purdue Journal of Service-Learning and International Engagement

Purdue University College of Pharmacy offers an international advanced pharmacy practice experience (APPE) in London, England, where student pharmacists have the opportunity to work with pharmacy specialists at St. Bartholomew’s Hospital. The COVID-19 pandemic has significantly impacted travel across the world and created the need to transition this experience from in-person to virtual.

Virtual interaction with international preceptors and revised research and clinical activities can provide students with a valuable learning experience.

Hair Care Catered To You, Sarah Reynolds, Meg Sorg

Purdue Journal of Service-Learning and International Engagement

People of color face barriers in healthcare every day, and my goal was to address one of these barriers. Healthcare settings stock products that are tailored for Caucasian hair and skin, so I wanted to add products targeted for Black patients' skin and hair. I added shampoo and lotion to the supply closet of Peyton Manning Children's Hospital as well as bonnets and durags for the patients to wrap their hair in to protect it while they sleep or rest. African American hair and skin requires different care. This is something that often goes unnoticed by healthcare professionals, and I …

Laini Fluellen Charities And Know Your Lemons: Squeezing Out Breast Cancer And Winning The Fight, Kayla Vasilko

Purdue Journal of Service-Learning and International Engagement

Each minute, a woman dies from breast cancer somewhere in the world. The first and most important tool a woman needs to have to win a fight against this disease is the education to identify breast cancer symptoms as early as possible. Laini Fluellen Charities, Inc. (LFC) is an organization dedicated to aiding women in the fight of triple-negative breast cancer (TNBC), a highly aggressive form of breast cancer that characteristically affects young women, has fewer treatment options, and results in lower survival rates overall. Laini Fluellen combats TNBC by representing those most disproportionally affected: young African American and Hispanic …

Pharmacy Students As Volunteer Medical Staff For American Diabetes Association Summer Camp, Emily Harvath

Purdue Journal of Service-Learning and International Engagement

For children living with a diagnosis of diabetes, com-munity support and education about proper disease management are critical for the mental and physical health of the child and their family. The experiences offered at summer camps hosted by the American Diabetes Association address both of these needs for the pediatric diabetes community. These camps provide children with the opportunity to participate in a traditional camp experience—swimming, rock climbing, tubing, and more—while giving parents peace of mind in the knowledge that their child’s diabetes will be closely monitored by a team of health care professionals. During my time as volunteer medical …

Student Pharmacists’ Response To A Pandemic: Service-Learning Through Contact Tracing, Antoinette Martin, William Harris, Alexander Szu-Wei Chao, Caroline Blankemeier, Diane Hobbs, Emily Hall, Emily Harvath, Madilyn Eberle, Monica L. Miller, Rakhi Karwa

Purdue Journal of Service-Learning and International Engagement

In March 2020, the SARS-CoV-2 (COVID-19) pandemic disrupted education nationwide. To safely deliver in-person classes, Purdue University contracted One-to-One Health, creating the Protect Purdue Health Center (PPHC). The PPHC was a central location for information, testing, and case management for Purdue students, staff, faculty and their dependents. Contact tracing is a proven public health measure that has been utilized to control the spread of infectious diseases by identifying and isolating potential active cases. The communicative nature of contact tracing, along with its need for clinical decision-making skills makes the student pharmacist an ideal candidate for aiding in this pandemic response. …

A Community Health Initiative: Health To The Power Of You, Stephanie Hendricks

Purdue Journal of Service-Learning and International Engagement

In April 2020, the COVID-19 pandemic impacted the number of visits to ambulatory care practices and was reported to have declined by nearly 60%. The extent of this decline is alarming as outpatient visits help manage chronic diseases in patients, such as diabetes, high blood pressure, and high cholesterol. This trend sparked an interest in pharmacist and student pharmacist, Dr. Cynthia Koh-Knox Sharp and Stephanie Hendricks, respectively, as it offered an opportunity to help serve the Greater Lafayette community. We created Health to the Power of You (Health^You), which targets two of Lafayette’s neglected populations: community members experiencing …

Adapting Global Service-Learning Project And Community Partnership Outcomes Using A “Tele-Engineering” Approach In Response To The Covid-19 Pandemic, Christiane Ley, Danielle Angert, Tessa Hudelson, Jordan Harris

Purdue Journal of Service-Learning and International Engagement

The Water Supply in Developing Countries (WSDC) service-learning course at Purdue University has fostered a strong partnership with the La Vega region in the Dominican Republic since 2012. During this time, an interdisciplinary group of engineering and science students has helped design drinking water treatment systems and the group has developed water, sanitation, and health (WASH) education materials. These WASH education and water safety approaches often have been conducted in person in the past. However, with the state of the COVID-19 pandemic and the inability to travel in the fall and spring semesters of the 2020–2021 academic year, the students …

Creating Reel Designs: Reflecting On Arthrogryposis Multiplex Congenita In The Community, Iris Layadi

Purdue Journal of Service-Learning and International Engagement

Because of its extreme rarity, the genetic disease arthrogryposis multiplex congenita (AMC) and the needs of individuals with the diagnosis are often overlooked. AMC refers to the development of nonprogressive contractures in disparate areas of the body and is characterized by decreased flexibility in joints, muscle atrophy, and developmental delays. Colton Darst, a seven-year-old boy from Indianapolis, Indiana, was born with the disorder, and since then, he has undergone numerous surgical interventions and continues to receive orthopedic therapy to reduce his physical limitations. His parents, Michael and Amber Darst, have hopes for him to regain his limbic motion and are …

Attitude Toward Companion And Guard Dogs In Hawaii: Health And Welfare Implications, Lynn Morrison, Julie Ann Luiz Adrian, Marina Kelley, Johana Hill, Zachariah Tman, Dana-Lynn Ko'omoa-Lange

People and Animals: The International Journal of Research and Practice

The island of Hawaii exhibits extremes in dog welfare ranging from dogs as family members to dogs used as commodities, either as guard or hunting dogs, with many lacking appropriate care. This study offers a preliminary exploration of people’s attitudes toward companion and noncompanion dogs and the health and welfare implications for humans and dogs. Data collection included interviews and surveys conducted among 20 companion dog/human and eight guard dog/human dyads. Blood pressure (BP) was monitored during interviews to assess stress. The results of the interview data led to five themes. The first two themes describing contexts of dog welfare …

Teaching With Data In The Social Sciences: The Purdue Report, Jane Yatcilla, Clarence Maybee, Bethany Mcgowan, Gang Shao, D Trevor Burrows

Libraries Reports

Purdue University Libraries participated in a multi-institution study about how instructors teach with data in social sciences courses. Thirteen semi-structured interviews were conducted with social sciences faculty who teach undergraduate students to use data, addressing questions about how faculty connect students to data; how students work with data; what types of support faculty have received that informs their teaching with data. Four broad themes emerged from qualitative coding of the interview transcripts: an array of purposes and practices for teaching about data; instructors' experiences, needs, and perspectives; managing wide-ranging student confidence and ability; technical concerns when teaching with data. The …

Considerations For Recommending Service Dogs Versus Emotional Support Animals For Veterans With Post-Traumatic Stress Disorder, Macy Porter, Melissa Y. Winkle, Ellen Herlache-Pretzer

People and Animals: The International Journal of Research and Practice

Background: Health care providers must understand factors that may guide the decision-making process for determining whether a veteran with post-traumatic stress disorder (PTSD) is appropriate for a service dog (SD) versus an emotional support animal (ESA), and assist SD training organizations in determining trained tasks that are suitable for the veteran’s needs.

Purpose: This study explored the perspectives of SD training organizations and factors for human health care providers to consider before recommending a veteran with PTSD for a SD versus an ESA. The researchers identified information that providers should give organizations to guide the SD training and placement process. …

Human- Animal Interaction To Support Well- Being At University: Experiences Of Undergraduate Students In The Uk, Aliya Khalid, Anne Rogers, Emily Vicary, Helen Brooks

People and Animals: The International Journal of Research and Practice

In the context of increasing concerns about student mental health and the therapeutic value of companion animals for mental health, there is limited understanding of the potential contribution of human- animal interaction in relation to undergraduate well- being. This study aimed to develop an in- depth understanding of the meaning and well- being roles attributed to human- animal interactions by undergraduate students in the UK. Using a qualitative research design, semistructured interviews were conducted with 60 students aged be-tween 18 to 23 years at a UK university of whom 39 implicated the role of companion animals in their well- being …

Can The Visits Of Dogs (Canis Lupus Familiaris) Influence The Mental Health (Anxiety And Depression) Of Male Aging Patients Institutionalized With Dementia In Health Care Units? A Pilot Study Of Madeira Island, Portugal, S. Vasconcelos, J. Azevedo, C. Casanova, H. Jardim, D. Neto, S. Jardim, C. Viegas

People and Animals: The International Journal of Research and Practice

Despite the fact that in the last decades, several mental health studies have shown that companion animals contribute to psychological and social well- being in humans (e.g., positive impacts have been observed in the elderly medicated for chronic diseases such as anxiety, dementia, and depression), bonds between humans and other animals continue to be under-estimated. The aim of this study is to assess the impact of an animal’s visits (twice a week, N = 30) in depression and anxiety levels of an institutionalized male population diagnosed with dementia. While some of these patients are being partially medicated with antidepressants and/or …

Quantitative Proteomics And Phosphoproteomics Reveal Tnf-Α-Mediated Protein Functions In Hepatocytes, Rodrigo Mohallem, Uma K. Aryal

Department of Veterinary Clinical Sciences Faculty Publications

Increased secretion of proinflammatory cytokines, such as tumor necrosis factor-alpha (TNFα), is often associated with adipose tissue dysregulation, which often accompanies obesity. High levels of TNFα have been linked to the development of insulin resistance in several tissues and organs, including skeletal muscle and the liver. In this study, we examined the complex regulatory roles of TNFα in murine hepatocytes utilizing a combination of global proteomic and phosphoproteomic analyses. Our results show that TNFα promotes extensive changes not only of protein levels, but also the dynamics of their downstream phosphorylation signaling. We provide evidence that TNFα induces DNA replication and …

Systemic Copper Disorders Influence The Olfactory Function In Adult Rats: Roles Of Altered Adult Neurogenesis And Neurochemical Imbalance, Sherleen Xue-Fu Adamson, Wei Zheng, Zeynep Sena Agim, Sarah Du, Sheila Fleming, Jason Cannon

School of Health Sciences Faculty Publications

Disrupted systemic copper (Cu) homeostasis underlies neurodegenerative diseases with early symptoms including olfactory dysfunction. This study investigated the impact of Cu dyshomeostasis on olfactory function, adult neurogenesis, and neurochemical balance. Models of Cu deficiency (CuD) and Cu overload (CuO) were established by feeding adult rats with Cu-restricted diets plus ip. injection of a Cu chelator (ammonium tetrathiomolybdate) and excess Cu, respectively. CuD reduced Cu levels in the olfactory bulb (OB), subventricular zone (SVZ), rostral migratory stream (RMS), and striatum, while CuO increased Cu levels in these areas. The buried pellet test revealed both CuD and CuO prolonged the latency to …

Mechanisms Of Neurotoxicity Associated With Exposure To The Herbicide Atrazine, Sydney C. Stradtman, Jennifer L. Freeman

School of Health Sciences Faculty Publications

Atrazine is an herbicide commonly used on crops to prevent broadleaf weeds. Atrazine is an endocrine-disrupting chemical mainly targeting the neuroendocrine system and associated axes, especially as a reproductive toxicant through attenuation of the luteinizing hormone (LH). Current regulatory levels for chronic exposure are based on no observed adverse effect levels (NOAELs) of these LH alterations in rodent studies. Atrazine has also been studied for its effects on the central nervous system and neurotransmission. The European Union (EU) recognized the health risks of atrazine exposure as a public health concern with no way to contain contamination of drinking water. As …

Concomitant Cannabis Misuse And Associations With Depression, Pain And Substance Misuse Among Patients Prescribed Opioids, M. Aryana Bryan, Elizabeth Charron, Omolola A. Adeoye-Olatunde, Jennifer Brown, Udi Ghitza, T. John Winhusen, Gerald Cochran

Department of Pharmacy Practice Faculty Publications

Background: Cannabis use is common among individuals with pain who are prescribed opioids, occurring in approximately 10% of this population. This study aims to explore the relationship between non-medical cannabis use and other health risks among individuals filling opioids at community pharmacies. Methods: This study was an exploratory secondary data analysis of a National Drug Abuse Treatment Clinical Trials Network (CTN)-sponsored study, Validation of a Community Pharmacy-Based Prescription Drug Monitoring Program Risk Screening, examining the relationship between risky cannabis use and depressive symptoms, pain, overdose, and other substance misuse among individuals filling opioid prescriptions in community pharmacies (N = 1440). …

Lean Six Sigma As An Enabler For Healthcare Operational Excellence In Covid-19, Olivia Mcdermott Dr, Antony Jiju

International Conference on Lean Six Sigma

1. Purpose -This paper aims to present the results of a qualitative research interview study on the utilization and importance of Lean Six Sigma methods in the Healthcare sector in COVID-19 and in pandemics in general.
2. Design/methodology/approach -a qualitative interview approach was utilised by interviewing leading Lean Six Sigma academics and practitioners who are expert in and have experience in Lean Six Sigma.
3. Findings – Lean Six Sigma methods are proven and can be utilised in pandemic situations to improve efficiency and resilience in the healthcare system and readiness for pandemics.
4. Research limitations/implications - One limitation of this research was that …

Application Of Lean Six Sigma To Reduce The Cost Of Regulatory Noncompliance., Reham Nour, Chad Laux

International Conference on Lean Six Sigma

1. Purpose

This research focused on the adoption of Six Sigma within FDA-regulated pharmaceutical companies to create an effective CAPA system for reducing the cost of noncompliance and supporting organizational performance.

2. Design/Methodology/Approach

This study utilized the DMAIC methodology, in a case study, to improve the CAPA process within a medical device company regulated by the FDA. All the critical requirements for compliance CAPA system was being defined from the FDA sources and the DMAIC model was be applied to improve and maintain CAPA performance.

3. Findings

Using the DMAIC approach supported identifying the bottlenecks and process variation. within CAPA. …

The Canine-Campus Connection, Mary Renck Jalongo

New Directions in the Human-Animal Bond

A primary mission of universities is promoting student success and well-being. Many college and university personnel have implemented initiatives that offer students the documented benefits of positive human-animal interaction (HAI). Accumulating evidence suggests that assistance dogs, therapy dogs, and shelter dogs can support student wellness and learning. The best programs balance the welfare of humans and canines while assessing students’ needs and complying with all laws and regulations. Contributors to this edited volume have drawn upon research across many disciplines as well as their extensive practical experiences to produce a timely and valuable resource—for administrators and students. Whether readers are …

More Than “Just” Walking: An Observational Study Of Dog-Related Physical Activities, Benedikt Hielscher, Udo Ganslosser, Ingo Froboese

People and Animals: The International Journal of Research and Practice

Dog ownership has been shown to correlate with physical activity (PA). However, knowledge about the intensities of dog-related PA (drPA) is still lacking. To investigate the duration and intensity of drPA in consideration of PA guidelines, an observational study of dog owners (DO) was conducted.

For this purpose, DO were recruited in metropolitan and nonmetropolitan regions of Cologne, Germany. A total of 44 male and female DO (18–64 years) without cardiovascular or cardiopulmonary diseases participated in the study. Validated questionnaires were used to determine the PA profile and relationship of DO to their dog. Participants reported their drPA in an …

Bearing Witness To The Beauty Of Enactive Kinesthetic Empathy Across Species In Canine-Human And Equine-Human Interactions: Participant-Observation Ethnographies, Donna A. Carlyle, Pamela Graham

People and Animals: The International Journal of Research and Practice

Through observations from ethnographic fieldwork the authors seek to highlight the significance of equine-human and canine-human communication to the fields of both human- animal studies and eudaimonia theories of human well-being. As we shared our insights through academic conversations about our respective research findings, we realized that both studies explore the enigmatic and significant concept of kinesthetic empathy in communication and relationship building between horses and young people and between dogs and young children. The canine-child setting (Study A) is a primary school and classroom in which the children voted to share their environment with a school dog, and the …

Development Of Continuous Flow Sonogashira Coupling Of Lead Anti-Cancer Small Molecule Inhibitors For Potential Treatment Of Acute Myeloid Leukemia, Yuta W. Moriuchi, Shruti A. Biyani, David H. Thompson

Discovery Undergraduate Interdisciplinary Research Internship

As the technology for science develops, the research strategy in medicines and therapeutics also improves. In this paper, I will cover the process of Sonogashira cross-coupling and Amide Coupling reaction for an anticancer agent in both batch and flow chemistry. Continuous Flow Chemistry has advantages such as being more efficient, safer, and faster. This paper studies the synthesis of HSNO608, an anticancer lead compound for Acute Myeloid Leukemia (AML), which has a specific potent activity to FTL3 Kinase. Inhibition of FLT3 Kinase leads to inhibition of downstream pathways such as MPK and P13K pathways. In this two-step experiment, the Sonogashira …

Pioneer Science And The Great Plagues: How Microbes, War, And Public Health Shaped Animal Health, Norman F. Cheville, Purdue University Press

Purdue University Press Books

Pioneer Science and the Great Plagues covers the century when infectious plagues—anthrax, tuberculosis, tetanus, plague, smallpox, and polio—were conquered, and details the important role that veterinary scientists played. The narrative is driven by astonishing events that centered on animal disease: the influenza pandemic of 1872, discovery of the causes of anthrax and tuberculosis in the 1880s, conquest of Texas cattle fever and then yellow fever, German anthrax attacks on the United States during World War I, the tuberculin war of 1931, Japanese biological warfare in the 1940s, and today’s bioterror dangers.

Veterinary science in the rural Midwest arose from agriculture, …

Therapy Dog Ownership As Serious Leisure For Members Of A Therapy Dog Volunteer Group, Jonathan R. Hicks, Mary Kramer

People and Animals: The International Journal of Research and Practice

Therapy dogs are used in a variety of settings, including prisons, hospitals, and schools, for the purposes of providing emotional and psychological support to humans. They are trained to be well behaved and to be perceived as supportive of humans. This study sought to explore the benefits to the human individuals who facilitate trained therapy sessions. Specifically considered were the ways in which therapy dog ownership is a form of serious leisure and the ways in which that leisure influences owners’ day- to- day lives. Findings suggest owners of therapy dogs experience enhanced personal enrichment, relationship with dog(s), and sense …

Are Nurses Joining The Ride? Equine-Assisted Activities And Therapies Review, Khalid Bandar Almasloukh, Pamela Stewart Fahs

People and Animals: The International Journal of Research and Practice

Background: Equine-assisted activities and therapies (EAAT) is a rapidly growing practice that is described as therapeutic and entertaining. Complementary therapies such as EAAT are gaining acceptance as the health care needs of the population are changing.

Method: This systematic review draws from four databases. The final review included 52 articles.

Purpose: To explain what is known about EAAT and identify literature gaps. Nursing and rural perspectives are included in the analysis and recommendations.

Findings: There are more than eight types of EAAT and different organizations around the world are providing certification for EAAT. Rural communities and organizations may benefit from …