Dual Membrane-Spanning Anti-Sigma 2 Controls Omv Biogenesis And Colonization Fitness In Bacteroides Thetaiotaomicron, Evan J Pardue, Tengfei Zhong, Nichollas E Scott, Biswanath Jana, Wandy Beatty, Juan C Ortiz-Marquez, Mohammed Kaplan, Clay Jackson-Litteken, Mario F Feldman

2020-Current year OA Pubs

UNLABELLED:

IMPORTANCE: Dual membrane-spanning anti-sigma factors (Dma) are a novel class of regulatory proteins found solely among Bacteroidota. Previous studies demonstrated the importance of Dma1 in vesiculation, but the overall role of the Dma family in Bacteroides physiology remains poorly understood. Here, we show that Dma2 modulates vesiculation and the expression of select polysaccharide utilization loci (PULs) that target host-associated glycans

Treating Depression With L-Methylfolate: A Review Of Evidence, Marianna G. Pettit

Epsilon Sigma at-Large Research Conference

Abstract

Introduction & Background: Depressive disorders have many different causes. Folate deficiency can sometimes be behind these disorders, due to this vitamin’s role in neurotransmitter synthesis. Some research suggests that supplementing with an active form of folate improves depressive symptoms with and without antidepressant use. Purpose Statement Question: For individuals with depressive disorders, does supplementation with L-methylfolate (LMF) reduce symptoms of depressive disorders with or without use of an antidepressant? Literature Review: A manual literature search for sources published within the past 7 years revealed 557 documents from four different databases. Key search words included, “depression,” “treatment,” …

Nurse-To-Patient Ratios In Adult Medical-Surgical Units, Kayleigh A. Runion, Emily G. Barnette, Maddison K. Wood, Jeremy Walker

Epsilon Sigma at-Large Research Conference

Nurse-to-patient ratios in adult medical-surgical floors vary across healthcare settings and have been linked to patient safety and quality outcomes. Nurse-to-patient ratios of 1 to 6 or greater are most common in practice settings, despite the growing evidence that higher nurse workloads are associated with increased mortality, longer length of stay, higher readmission rates, mistakes, and miscommunication in nursing care. The purpose of this evidence-based practice project is to examine whether applying safer nurse-to-patient ratios, 1 to 4 instead of 1 to 6 or higher, improves patient safety outcomes. Using the Johns Hopkins Evidenced-Based Practice Model, a project was put …

Does Time Matter? Comparing 8- And 12-Hour Registered Nurse Shifts., Ava P. King, Abby L. Goodall, Cheryl L. Goodall, Makayla B. Ramsey, Imari K. Golden

Epsilon Sigma at-Large Research Conference

This project analyzes the effect that registered nurse's shift length has on patient outcomes and quality of care. The research specifically explores a well-debated healthcare issue; are 12-hour shifts associated with poor patient care due to fatigue? By comparing errors made in 12-hour and 8-hour shift lengths of registered nurses, it can be determined if a trend can be seen in declining patient care. Not only will this research shed light on nurses' fatigue and burnout, but it will also showcase the patient dangers associated with overworking. Overall, the goal is to bring awareness using statistical data that explains why …

A Systematic Literature Review On Alternative Treatment Modalities In Adults With Treatment Resistant Depression, Brian Miller

Epsilon Sigma at-Large Research Conference

Abstract

            Currently, Psychiatric Mental Health Nurse Practitioners (PMHNPs) often defer to electroconvulsive therapy (ECT) for individuals with TRD who fail to achieve resolution of their disorder. However, many individuals do not meet criteria for ECT or decline the treatment due to side effects and associated risks. To synthesize potential alternative treatments and address the current gap in literature that does not include first-line preferred electroconvulsive therapy (ECT), a systematic literature review was conducted using the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA 2020). Databases searched for this review included the Cumulative Index to Nursing and Allied Health Literature …

The Impact Of Social Interaction On Patient Well-Being With Transition Into Long-Term Care Settings: A Review Of Interventions For Improved Patient Outcomes, Helen Whitney Harmon

Epsilon Sigma at-Large Research Conference

Abstract

Purpose: When individual patients are transitioned from home or acute care settings to more long-term care environments such as skilled nursing units or assisted living facilities, the residents are at an increased risk of experiencing loneliness, which is linked to depression, anxiety, and increasing cognitive decline, and other detrimental outcomes.

Aims: Combinations of peer-reviewed qualitative and quantitative research studies were analyzed to determine what factors contributed to changes in patient well-being, mental health and overall quality of life during these transitions.

Methods: One article focusing on preventable healthcare transitions in patient population was able to link higher medical acuity …

Does Mandated Paid Maternity Leave Affect Postpartum Depression?, Amaya S. Hall, Shay Y. Bullwinkel, Loran M. Hurley, Sara Cook

Epsilon Sigma at-Large Research Conference

This project analyzes the effects that paid maternity leave has on postpartum depression. Upon reviewing multiple studies, it has been demonstrated that unpaid maternity leave is associated with postpartum depression. Throughout researching postpartum depression rates, it has been proven to be much higher in unpaid leave compared to paid maternity leave. Mothers that have the burden of staying home with their infants and having to juggle time off work, without being compensated, are at an increased risk of experiencing postpartum depression. It has been shown that when a mother is able to focus on her child and her healing after …

The Role Of Nurses In Robotic-Assisted Surgery, Tehya Wiedemeier, Gretchen Faith Grambow, Ella Froehlich, Whitney Anna Holmes

Epsilon Sigma at-Large Research Conference

The research examines the evolving role of nurses in robotic-assisted surgery. As the technology advances, the nursing role is expanding beyond the traditional responsibilities. The method of literature review for this study was completed through deductive content analysis based off three data bases called Science Direct, PubMed (Medline), and Scopus. Current research is working towards trying to bring educational awareness to the role of nurses within the robotic surgery environment and what new skills they will have to acquire.  For nurses to successfully fit into the role of assisting within robotic surgery, they will need to obtain a higher level …

Postpartum Psychosis Risk In Women With Bipolar Disorder, Rachel R. Lay

Epsilon Sigma at-Large Research Conference

Psychiatric relapse and postpartum psychosis pose vital psychological threats to women with bipolar disorder. The phase after delivery implies a great number of biological, psychological, and social alterations that might predispose to mood fluctuations and extreme psycho-psychiatric behavior. A systematic literature review assessed the recent literature on postpartum relapse risk, contributors, and maternal outcomes in women with bipolar disorder. Systematic search of three electronic databases, CINAHL, PubMed, and PsycINFO, revealed 168 studies dating back to 2022. Title and abstract screening of 124 articles was carried out after elimination of duplicates and other eligibility criteria. Eighteen articles were full-text reviewed, and …

Adolescent Depression, Telepsychiatry, And Access, Dustin Strickland

Epsilon Sigma at-Large Research Conference

Adolescent depression is prevalent, undertreated, and associated with long-term morbidity if left untreated. Several structural barriers impede timely access to specialty mental health care in this age group. Telepsychiatry, including therapist delivered videoconference psychotherapy and internet delivered cognitive behavioral therapies (ICBT) have been developed to expand access and continuity of care for adolescents. This modality, however, has not been thoroughly evaluated to determine the effectiveness of telepsychiatry in improving access to services and its ability to reduce depressive symptoms in adolescence. A structured literature review identified six primary studies and four complementary systematic reviews evaluating this topic. Randomized trials show …

Building The Nursing Leadership Pipeline: Outcomes Of A Statewide Emerging Nurse Leader Fellowhip, Kathleen Kinser Dnp, Aprn, Belinda J. Fleming Phd, Christie Manasco Phd, Monaco M. Briggs Edd, Yan Cao Phd, Jennifer Hitt Phd

Epsilon Sigma at-Large Research Conference

Healthcare systems increasingly require skilled nurse leaders to address workforce shortages, quality improvement demands, and complex care environments. However, many nurses transition into leadership roles without formal preparation. In this quality improvement project, nurse scientists Kathleen Kinser DNP; Belinda Fleming, PhD; and Christie Manasco, PhD, from the Tennessee Center for Nursing Advancement (TCNA) evaluated outcomes of the Emerging Nurse Leader Fellowship developed to strengthen foundational leadership competencies among novice nurse leaders. Guided by transformational leadership theory, the fellowship was a statewide, cohort-based, instructor-led, asynchronous online program emphasizing practical leadership development and application in clinical settings. Two cohorts participated and completed …

Implementing The Abcdef Bundle In A Rural Critical Care, Kayla Hubbard

Epsilon Sigma at-Large Research Conference

Patients admitted to the critical care unit are at risk of debilitating adverse outcomes including Delirium, Post intensive care syndrome (PICS), debility, wounds, depression, and both mental and physical impairments. Complications related to ICU care can easily be combatted by using a multidisciplinary approach. The ABCDEF bundle serves to incorporate all aspects of a critically ill patients care in a simple, easy to follow bundle focusing on assessment of pain (A), both spontaneous awakening ang breathing trials (B), choice of sedation/analgesic (C), delirium (D), early mobility (E), and family involvement (F). A quality improvement project was designed and piloted in …

Using Path Analysis To Examine The Psychological Well-Being Model For U.S. College Students, Pi-Ming Yeh, Cheng-Huei Chiao, Gavin Waters

Epsilon Sigma at-Large Research Conference

Background: College students’ psychological well-being and mental health issues are very important in this society. Little is known about a comprehensive psychological well-being model for college students.

Purpose: The purpose of this study was using Path Analysis to examine the Development of Personality and Psychological Well-Being Model among US college students.

Methods: This was a cross sectional, descriptive design. The 481 participants were recruited from nursing and business college students in the United States. After IRB approval, the trained researchers explained this study to college students. After agreeing to participate, they signed an informed consent form. Upon completion of a …

Occupational Therapy For Maternal Pelvic Floor And Mental Health: A Holistic Approach To Recovery, Diana S. Theodore

Student Capstone Papers

Maternal pelvic floor dysfunction (PFD) is highly prevalent yet often underrecognized in occupational therapy practice, despite its significant impact on mental health, daily function, and quality of life. Many postpartum women experience symptoms such as urinary incontinence, pain with intimacy, and pelvic organ prolapse, which are frequently normalized or left untreated. Occupational therapy practitioners often have limited training in addressing the complex relationship between pelvic floor function and maternal mental health, contributing to gaps in care. The purpose of this capstone project was to develop a comprehensive handbook for occupational therapy students and practitioners integrating pelvic floor function and maternal …

Supporting Independence In Adults With Down Syndrome Through Parent Education And Program Development At Gigi’S Playhouse, Kristen Powlas

OTD Capstone Projects

This doctoral capstone project was completed in partnership with GiGi’s Playhouse Nashville, a non-profit organization that provides free educational and therapeutic programming for individuals with Down syndrome across the lifespan. The primary focus of this project was to design and implement a full semester of curriculum for the GiGi Prep adult education program, with an emphasis on developing foundational skills to support increased independence and participation in daily life.

Course content was delivered through an occupational therapy lens and included topics such as communication, emotional regulation, money management, coping strategies, self-advocacy, job skills, and independent living skills. In addition to …

An Injury Prevention Program For Musculoskeletal Injuries, Kima Esters, Rebecca King

Spring 2026 OTD Capstone Symposium

Musculoskeletal injuries pose a significant risk to occupational performance, participation, and overall well-being due to resulting functional deficits. Occupational therapists play a crucial role in managing these impairments and promoting independence to reduce the risk of reinjury, psychological symptoms, and long-term physical limitations while supporting re-engagement in activities of daily living and meaningful occupations. This injury prevention program focused on educating and training healthcare professionals in prevention and management strategies, including postural awareness, work simplification, ergonomics, adaptive equipment, mental health strategies for stress and anxiety management, and sleep preparation to improve patient outcomes and overall quality of life.

Community-Based Program To Support The Occupational Needs Of Middle Eastern Refugee Women Transitioning Into Western Society, Zuha A. Mohammad, Cassandra Nelson

Spring 2026 OTD Capstone Symposium

Middle Eastern refugee women resettling in Western societies often experience barriers that disrupt participation in meaningful occupations, including language barriers, unfamiliar systems, financial challenges, and social isolation. These challenges can limit independence and community participation during the resettlement process. Occupational therapy is well-positioned to address these barriers through culturally responsive, occupation-based interventions.

This capstone project developed and implemented a community-based program designed to support Middle Eastern refugee women during early resettlement. The program focused on key areas including system navigation, financial literacy, home safety, stress management, self-advocacy, and community engagement. Educational sessions and practical activities were used to promote skill …

Advancing Athletic Recovery: The Role Of Occupational Therapy In Sports Medicine, Hannah E. Oakerson, Rebecca King, Rebecca Caudrillier

Spring 2026 OTD Capstone Symposium

This capstone project aimed to assess whether an occupation-based educational program could improve recovery engagement, self-efficacy, and quality of life in athletes following sports-related injuries. An Athlete Recovery Guidebook was designed, implemented, and evaluated within an outpatient sports medicine setting. The guidebook provided structured education on recovery routines, symptom management, and health habits, while supporting integration into daily life. Findings from pre- and post-surveys and qualitative feedback suggest improvements in recovery knowledge, confidence, body awareness, and overall quality of life following program implementation.

Rhode Island Right To Life: Veritas Grant Funded Internship Summer 2025, Ekaterina Rau

Biology Student Scholarship

No abstract provided.

Representation Of Active Girls, Women, And Female Athletes In Low Energy Availability Research: A Review, Ahnna E. Faust, Alexis V. Viehl, Melissa T. Lodge

Health Sciences Student Scholarship

More female athletes are participating in sports today than ever before, yet they remain underrepresented in sport and exercise science (SES) research. According to a 2021 review, 34% of SES research participants are females and just 6% of studies used female-only designs. Female athletes are also at an increased risk for low energy availability (LEA), or a mismatch between energy intake and exercise energy expenditure. However, the representation of women in research related to LEA remains unclear. PURPOSE: This study aimed to (a) evaluate the representation of girls, women, and female athletes in LEA research, and (b) explore methodological characteristics …

As A Component Of Aseptic Technique, Bunsen Burners Do Not Decrease Deposition Of Microbe-Containing Particulates, Kate Devincent, Ariana Carretta, Vanessa Colina, Imani Laporte, Tyler Oung, Hannah Gavin

Health Sciences Student Scholarship

No abstract provided.

Using Lean Body Mass To Calculate Resting Metabolic Rate Across Gender Identities, Kara Dixon, Liza Goetcheus, Brett R. Ely

Health Sciences Student Scholarship

Accurate estimate of resting metabolic rate (RMR) is important for tailoring nutrition support in clinical settings. Metabolic rate is often calculated using the Harris-Benedict equations, which estimate metabolic rate using separate equations for men and women. PURPOSE: This study aims to develop a more inclusive, single predictive equation based on lean body mass instead of gender. METHODS: Six healthy individuals (Age: 22±5; BMI: 22.3±0.7) underwent assessment of resting metabolic rate (RMR) using indirect calorimetry, and full-body dual energy x-ray absorptiometry to measure lean body mass. RMR was divided by lean body mass to examine the relationship between muscle mass and …

The Impact Of Exercise In The Heat On Lactation Performance In Lactating Women, Elizabeth G. Helsley, Olyvia Bendza

Health Sciences Student Scholarship

PURPOSE: to determine whether acute exercise in the heat alters 24-hr breastmilk production and composition among lactating women. METHODS: Seven participants (34±5yrs, 163.7±4.8cm, 66.7±3.0kg, 25.0±14.2 weeks postpartum) completed the study. Participants were eligible if they were breastfeeding (6-week to 12-month infants), aged 18-45 years old, and delivered between 37 and 42 weeks. The study was a randomized, crossover design with three visits: 1) baseline and metabolic heat production testing; 2) acute exercise in the heat (HOT; 36°C, 40% relative humidity[RH]), and 3) acute exercise in a thermoneutral environment (THERM; 20°C, 20%RH). Participants walked for 60 minutes at 8 watts per …

From Data To Action: Enhancing Public Health Communication & Information Dissemination, Ryan Hayden, Devon Donovan

Health Sciences Student Scholarship

No abstract provided.

Restoring Moral Imagination: A Pilgrimage Of Ethical Formation In Prelicensure Nursing, Hannah Dube, Francesca Kearns

Student Posters & Conference Presentations

No abstract provided.

Simulation-Enhanced Ethics Education: An Interdisciplinary Strategy To Strengthen Ethical Awareness And Communication, Sophia Calle

Student Posters & Conference Presentations

No abstract provided.

The Impact Of Covid-19 On Quality Of Care In Hospital Settings, Sophia Callahan

Health Sciences Student Scholarship

No abstract provided.

Decreasing Catheter Associated Urinary Tract Infection Through Reinforcement Of Hand Hygiene Compliance In A Rehabilitation Unit, Gloria Ihenwe

Doctor of Nursing Practice Final Project Abstract

Purpose

The purpose of this project is to decrease the CAUTI rate among adult rehabilitation patients with indwelling catheters from 40% to 1% through improved staff hand hygiene (HH) compliance and to increase hand hygiene compliance from 45.24% to 60.47% within 3 months. The secondary aim is that staff will report self-improvement in hand hygiene knowledge and technique.

Background

Catheter-associated urinary tract infections (CAUTIs) are common preventable healthcare-associated infections. Inconsistent HH compliance among direct care staff remains a common challenge and can contribute to infection risks and transmission of microorganisms

Methodology

The Plan-Do-Study-Act (PDSA) quality improvement model guided the implementation …

Health Is Where The Huddle Is, Lyndsey Anthony, Anna E. Komistek, Philip C. Pritchett, Emma K. Swanson

SPARK Symposium Presentations

“Health is Where the Huddle Is”

Huddles are an evidence-based strategy to facilitate a culture of safety within nursing teams. A review of 158 huddle studies found that 44.3% reported improved clinical outcomes and 24.3% showed fewer medical errors when huddles were implemented (Pimentel et al., 2021). Currently, a local hospital’s 13-bed ICU lacks an effective system for nursing staff to huddle due to staffing constraints and the absence of monitor technicians, creating safety concerns when nurses leave monitors unattended. This project aims to implement an effective, nurse-led shift huddle that maintains continuous patient monitoring while also strengthening patient safety …

Chemical And Pharmacological Mechanisms Of Calcium Oxalate Stone Inhibition: Citrate, Thiazides, And Emerging Therapies, Grace Tidwell

SPARK Symposium Presentations

Calcium oxalate (CaOx) kidney stone formation has prompted the development of a variety of pharmacological therapies designed to reduce the risk of crystallization by chemically modifying a patient’s urinary composition and thereby reducing urinary supersaturation of stone-forming ions. This paper reviews key drug classes that inhibit CaOx crystallization, such as citrate supplements, which bind calcium and increase pH levels within the urine, and thiazide diuretics, which act on the kidneys to increase calcium reabsorption into the bloodstream. In addition, the use of polyphenol-based compounds and gut microbiome therapies is examined for their potential roles in stone prevention. Ultimately, by focusing …