Medicine and Health Sciences Commons^™

Nursing The Wright Way: A History Of Nursing At Wright State University, 1973-2023, Donna Miles Curry

Books Authored by Wright State Faculty/Staff

This book explores the history of an innovative nursing education program in Dayton, Ohio from its creation in the 1970s until 2023. On the cutting edge with a theory driven curriculum this program went from BSN, adding the master's degree with advanced practice options and also a DNP.

The Impact Of The Gut-Brain Axis On Alzheimer’S Disease, Elissa Wakim

Best Integrated Writing

Elissa’s review for the Graduate Biomedical Review focuses on the links between the gastrointestinal tract and the brain; the gut-brain axis and the development of Alzheimer’s disease. As a student in the Microbiology and Immunology Masters Program Elissa was particularly interested in the gut microbiota and their connection to neurodegenerative disease. She tidily reviewed the literature and wrote a fascinating and compelling piece of work.

Characterizing The Polyamorous Experience Through Research, Kacey O'Harra

Best Integrated Writing

Scientific study of polyamory and the individuals who practice it has seen a sharp increase in the last decade, revealing data and subjective experiences that support their capacity to be closely intimate and fulfilling, to bolster personal development, to provide a positive and stable family environment, and to mutually strengthen the bonds of each relationship involved. Understanding the unique experiences and challenges faced by polyamorous lovers is essential for cultural competence in relational research, clinical practice, institutional regulations, and moving toward greater social acceptance. Examined here are the associated stigmas and their impacts on polyamorous individuals, the motivations people have …

Balancing The Mind: The Role Of Selective Serotonin Reuptake Inhibitors In Managing Anxiety, Olivia Mace

Best Integrated Writing

Olivia’s senior capstone review article focuses on the role of the selective serotonin reuptake inhibitor (SSRI) escitalopram in the management of anxiety. SSRIs have been successfully used to treat depression for decades, with fluoxetine (Prozac) being introduced to the US market in 1987. Recently it has been found that the SSRI escitalopram has efficacy in treating anxiety as well as depression. Olivia’s review is detailed and timely. Unmanaged anxiety and depression are common among students and this review will be of interest to students, parents and the university population in general.

Exploring The Systems-Related Factors Influencing Depression And Anxiety In The Private Healthcare System: A Nursing Student’S Perspective, Andrea Cessna

Best Integrated Writing

This paper presents a student’s critical synthesis of the literature and excellent grasp of the application of the World Health Organization Health Systems Building Blocks Framework to identify strengths, and improvement opportunities for nursing interventions in mental health care. The student’s writing demonstrates an awareness of factors that impact complex health systems in nursing practice which is an important competency in system-based practice.

The Potential Role Of Txa In Treating Brain Hemorrhage, Elijah Byrd

Best Integrated Writing

Elijah Bird’s essay provides an excellent review of the existing research and explores the promising possibilities of TXA in the treatment of brain hemorrhages.

Best Integrated Writing 2024 - Complete Edition, Wright State University School Of Humanities And Cultural Studies

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University. This is the first issue after a 5 year hiatus.

Weight Health In The Modern Lens: Investigating The Intersectionality Of Obesity, William Bohne, Anthony Onochie

Scholarship in Medicine - All Papers

Purpose The purpose of this study is to investigate the relationship between these social determinants of health and obesity to provide a better understanding of geographical differences in obesity rates. Methods All data was collected using countyhealthrankings.org. The variables that were studied included access to exercise, food insecurity, and life expectancy due to previous literature demonstrating probable association between these variables and the prevalence of obesity. Results Statistically significant increase in number of adults with obesity from 2016 to 2022 (32% to 37%). Statistically significant weak, negative correlation between access to exercise and obesity (r=-.306). Statistically significant weak, negative correlation …

Obstetrics Emergency Labor And Delivery Case Simulations With Normal Vaginal Delivery Demonstration: A Hands-On Simulation For Clerkship Students, Emily A. Young, William A. Winter, Robyn N. D'Agostino, Rose A. Maxwell, Sheela Barhan, Marilyn Kindig

Obstetrics and Gynecology Faculty Publications

Introduction: Simulation is rarely used for medical student education in the field of obstetrics. This method is an effective model of learning for topics that are encountered in clinical situations and for topics that pose significant risk to patients when an untrained individual is involved. Methods: A 2-hour obstetric delivery simulation session was developed and incorporated into the third-year obstetrics and gynecology clerkship rotation at Wright State University Boonshoft School of Medicine. Medical students completed self-guided content reviews with resources provided prior to the session. During the session, each medical student conducted a normal vaginal delivery and one of the …

Review On Therapeutic Potential Of Phytochemicals From Medicinal Plants, Iqra Afzal, Ume Habiba, Humaira Yasmeen

Journal of Bioresource Management

Nature has provided plants with a vast range of phytochemicals. These phytochemicals are enriched with different pharmacological activities. These pharmacological activities have a potential to be wisely used for therapeutic purpose. It can be utilized in so many ways for the expansion of therapeutic strategies. With the advancement in the field of medicine and due to increasing side effects of synthetic medicines there emerges a need to discover novel therapeutic remedies. Medicinal plants serve as the best source for the manufacture of new remedies for many diseases. Medicinal plants bear a potential towards treating incurable chronic diseases. The aim of …

Ethnobotanical Study Of Antihemorrhagic Plants In The Skikda Region (North East Of Algeria), Nabila Souilah, Hamdi Bendif, Abdelkrim Benaradj, Abdelouaheb Belaid, Scherazad Mekious

Journal of Bioresource Management

Our survey was carried out at the level of 17 Municipalities of the Province of Skikda. Questionnaire sheets were distributed to 55 herbalists and 350 locale population (informants). The processing of survey data with the local population shows us that women (52 %) have more knowledge of phytotherapy compared to men (48 %) with a fairly high level of education. For the herbalists, we found that most are men (85.45 %) aged between 31-40 years (29.09 %) and 41-50 years (25.45 %), and with level of university study (36.36 %). On the other hand, 52.73 % of herbalists said they …

‘Things That You Can’T Really Suppress’: Adverse Childhood Experiences In The Narratives Of People With Opioid Use Disorder, Sydney Silverstein, Josef Rivera, Danielle Gainer, Raminta Daniulaityte

Psychiatry Faculty Publications

While numerous studies have established relationships between Adverse Childhood Experiences (ACEs) and adult substance use, few qualitative studies have explored the differing ways in which experiences of childhood adversity are emplotted into narratives of drug use and recovery. This paper analyzes qualitative data collected as part of a mixed-methods longitudinal study of people with opioid use disorder. Narratives of adverse childhood experiences emerged unprompted. After coding qualitative data for mention of ACEs, we thematically analyzed coded data using a framework of critical phenomenology and constructed a four-part typology to differentiate the ways that ACEs were emplotted into narratives. Our …

The Persistence Of Blue Ash In The Aftermath Of Emerald Ash Borer May Be Due To Adult Oviposition Preferences And Reduced Larval Performance, Don Cipollini, Emily Morton

Biological Sciences Faculty Publications

1. We examined the health of mature blue ash, Fraxinus quadrangulata, in two forests in southwestern Ohio in relation to that of mature white ash, F. americana, and examined the potential importance of oviposition preferences and larval resistance in the persistence of blue ash.
2. Both blue ash and white ash were largely unaffected by emerald ash borer in 2012. By 2018, nearly 90% of the blue ash trees observed in these forests had full or nearly full canopies, as opposed to less than 20% of the white ash encountered in our studies. In 2021, blue ash maintained a …

Incidental Recognition Of Umbilical-Portal-Systemic Venous Shunt Diagnosed During Bpp For Decreased Fetal Movement, Kathleen Lundeberg, Adam Hiett

Obstetrics and Gynecology Faculty Publications

Background: The prevalence of prenatally diagnosed umbilical-portal systemic venous shunts (UPSVS) is reportedly rare, ranging from 0.003-0.209% [1]. Disruption in the normal development of the fetal venous system can be caused by primary failure of a system or by secondary occlusion of an already transformed system [2]. While UPSVS’s are rare, the downstream effects are potentially fatal, including intrauterine growth restriction, high output cardiac failure, associated neonatal morbidity and mortality, and thus necessitate early detection with appropriate monitoring.

Introduction: The patient was a 21-year-old G2P1001 who presented to the Maternal Fetal Medicine Ultrasound Genetics (MFMUG) clinic at 36w2d for a …

Integrating An Evidence Based Medicine Module Presentation Into The Ob-Gyn Clerkship, Judith Mathess, Betsy Gauthier, Zenab Saeed, Ngozi Anachebe, Rose A. Maxwell, Jason C. Massengill, Marilyn Kindig

Obstetrics and Gynecology Faculty Publications

Introduction: During the preclinical curriculum, students are introduced to EBM principles, however structured application to clinical medicine varies throughout clinical experiences. Application of EBM in a clinical educational environment affords students opportunities to practice required skills.

Methods: Students selected a patient case and formulated a question related to diagnosis ortreatment using the PICO framework. Students selected research publications related to the patient case, critically appraised their validity and generalization, and developed a comprehensive presentation involving a case summary and related EBM topics, which were evaluated by a faculty member using a rubric developed for the project. To assess the effectiveness …

Wright State University's Celebration Of Student Research, Scholarship & Creative Activities From Thursday, October 26, 2023, Wright State University

Symposium of Student Research, Scholarship, and Creative Activities Abstract Books

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Celebration of Student Research, Scholarship & Creative Activities on October 26, 2023.

Homeostatic Synaptic Plasticity Of Miniature Excitatory Postsynaptic Currents In Mouse Cortical Cultures Requires Neuronal Rab3a, Andrew G. Koesters, Mark M. Rich, Kathrin L. Engisch

Biological Sciences Faculty Publications

Following prolonged activity blockade, amplitudes of miniature excitatory postsynaptic currents (mEPSCs) increase, a form of homeostatic plasticity termed “synaptic scaling.” We previously showed that a presynaptic protein, the small GTPase Rab3A, is required for full expression of the increase in miniature endplate current amplitudes following prolonged blockade of action potential activity at the mouse neuromuscular junction in vivo (Wang et al., 2011), but it is unknown whether this form of Rab3A-dependent homeostatic plasticity shares any characteristics with central synapses. We show here that synaptic scaling of mEPSCs is impaired in mouse cortical neuron cultures prepared from Rab3A-/- and Rab3A Earlybird …

Case Study: The Elusive Vaginal Leiomyoma, Fiona Hodges, Roziya Tursunova, Kelly Nagy, Halei Wong, Wright State University Boonshoft Som Department Of Obstetrics And Gynecology, Wright Patterson Air Force Base Department Of Obstetrics And Gynecology

Obstetrics and Gynecology Faculty Publications

This poster was presented at the September 2023 Armed Forces District Meeting.

Nutritional Profile And Health Benefits Of Stevia Rebaudiana Bertoni: An Updated Review, Ishrat Fatima, Mubashrah Munir, Sehrish Sadia, Akash Tariq, Rahmatullah Qureshi

Journal of Bioresource Management

Aim of this comprehensive review is to document the up-dated data about pharmaceutical potential of Stevia rebaudiana Bertoni with special focus on its antioxidant activity. A total of 184 research articles were reviewed and five research engines were used to collect the data. The S. rebaudiana (Asteraceae) is indigenous to South America, now cultivated in many countries worldwide to be used as a natural bio-sweetener. Various nutritionally and medically important bioactive compounds such as diterpene glycosides, fatty acids, alkaloids, tannins, saponins, anthraquinones, phenolics, flavonoids, carbohydrates, carotenoids, steroids, polysaccharides and other phytochemicals constitute chemical composition of Stevia. Owing to the …

Radiographic Measurements Correlate To Isolated Posterolateral Corner (Plc) Injury In A Novel Cadaveric Model, Joseph D. Henningsen, Scott Huff, Andrew Reichard, Andrew W. Froehle, Anil Krishnamurthy

Kinesiology and Health Faculty Publications

Introduction: Injury to the posterolateral corner (PLC) of the knee often requires surgical reconstruction. There remains no consensus on treatment for PLC injury, and, therefore, it is imperative to have a reproducible injury model to improve the general knowledge of PLC injuries. A novel cadaveric model of isolated PLC injury is proposed and evaluated using radiographic parameters as well as gross dissection.

Material and methods: All protocols were reviewed by the Human Investigation and Research Committee of the home institution and were approved. Translational force in a defined posterior and lateral direction was applied to cadaveric native knees to induce …

Novel Enhanced Recovery After Surgery Pathway Reduces Length Of Stay And Postoperative Opioid Usage In Adolescent Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion, Kristen Spisak, Matthew Thomas, Zachary J. Sirois, Alvin Jones, Lucinda M. Brown, Andrew W. Froehle, Michael Albert

Kinesiology and Health Faculty Publications

Purpose: The goal of this study was to compare our institution’s recently implemented enhanced recovery after surgery (ERAS) protocol to previous post-operative management for adolescent idiopathic scoliosis patients undergoing posterior spinal fusion, specifically assessing length of stay, opioid consumption, and pain scores.

Methods: This is a retrospective analysis that compares the length of stay, opioid consumption, and pain scores of patients undergoing posterior spinal fusion for adolescent idiopathic scoliosis. Patients were analyzed prior to the implementation of our ERAS protocol, deemed the traditional pain pathway (TPP), to those who underwent the ERAS pathway. All patients undergoing posterior spinal fusion for …

A Cohort Study Assessing The Impact Of Anki As A Spaced Repetition Tool On Academic Performance In Medical School, Michael M. Gilbert, Timothy C. Frommeyer, Garrett V. Brittain, Nickolas A. Stewart, Todd M. Turner, Adrienne Stolfi, Dean Parmelee

Pediatrics Faculty Publications

Introduction

Anki is an application that capitalizes upon the techniques of spaced repetition and is increasingly utilized by medical students for examination preparation. This study examines the impact of Anki usage in a medical school curriculum on academic performance. Secondary objectives analyzed individual Anki utilization and a qualitative assessment of Anki use.

Methods

A cohort-control study was conducted at Boonshoft School of Medicine. One hundred thirty first-year medical students were enrolled in an Anki utilization training program from July 2021 to September 2021. Training included educational Anki courses and subsequent survey data collection over Anki usage. Data variables included all …

A Review On Antibiotic Resistance And The Use Of Medicinal Plants In The Management Of Uropathogenic Bacteria, Hubza Ruatt Khan, Mehvish Javeed, Iqra Batool, Rabeea Anwar, Asma Ashraf, Sara Janiad

Journal of Bioresource Management

UTIs are the most prevalent infections and are caused by uropathogenicmicrobes such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus spp. Antibiotic resistance has hampered the management of UTIs over the years, with direct repercussions on the treatment cost, the infection severity, and the duration of hospitalization. This review discussed the route of infections, risk factors connected to UTIs, antibiotic resistance issues as well as an alternative therapy to overcome the problem of antibiotic resistance. The medicinal plants which have been utilized for thousands of years to cure a variety of ailmentsrepresent a significant antibiotic …

Assessment Of Antimicrobial Competence Of Epiphytes And Endophytes From Osmium Basilicum And Trigonella Foenum Graecum, Iram Asim, Atia Iqbal, Muhammad Ikrama Tanveer

Journal of Bioresource Management

Plant-associated bacteria are an unexplored group of microorganisms that has enormous potential. These bacteria are the source of finding new antimicrobial substances. The present study aimed to isolate and characterize the epiphytes and endophytes from Osmium basilicum and Trigonella foenum graecum plants and to determine their antimicrobial potential against pathogenic bacteria from Nishtar Hospital Multan, Pakistan. The sum of 18 stems and roots along leaf specimens were assembled as of the plant's Osmium basilicum plus Trigonella foenum graecum as of the distinct locales of the Multan city. Overall 73 bacterial strains were isolated and their colony morphology, gram staining, spore …

Gabaergic Synaptic Scaling Is Triggered By Changes In Spiking Activity Rather Than Transmitter Receptor Activation, Carlos Gonzalez-Islas, Zahraa Sabra, Ming-Fai Fong, Pernille Bülow, Nicholas Au Yong, Kathrin Engisch, Peter Wenner

Biological Sciences Faculty Publications

Homeostatic plasticity represents a set of mechanisms that are thought to recover some aspect of neural function. One such mechanism called AMPAergic scaling was thought to be a likely candidate to homeostatically control spiking activity. However, recent findings have forced us to reconsider this idea as several studies suggest AMPAergic scaling is not directly triggered by changes in spiking. Moreover, studies examining homeostatic perturbations in vivo have suggested that GABAergic synapses may be more critical in terms of spiking homeostasis. Here we show results that GABAergic scaling can act to homeostatically control spiking levels. We find that increased or decreased …

Effects Of Pubertal Growth Variation On Knee Mechanics During Walking In Female And Male Adolescents, Andrew W. Froehle, Brian A. Edwards, Matthew Peterson, Brian Meyerson, Dana Duren

Kinesiology and Health Faculty Publications

Introduction: Puberty substantially alters the body's mechanical properties, neuromuscular control, and sex differences therein, likely contributing to increased, sex-biased knee injury risk during adolescence. Female adolescents have higher risk for knee injuries than male adolescents of similar age engaging in similar physical activities, and much research has investigated sex differences in mechanical risk factors. However, few studies address the considerable variation in pubertal growth (timing, pace), knee mechanics, and injury susceptibility within sexes, or the impact of such growth variation on mechanical injury risk.

Objectives: The present study tested for effects of variation in pubertal growth on established mechanical …

Linking Science And Literacy Through Multimodal Text Sets: Student Perspectives, Heba Abdelnaby, William L. Romine, Delinda Van Garderen, Tracey Milarsky, Ankita Agarwal, Qingli Lei, Cassandra Smith, Amy Lannin, William Folk, Rachel Juergensen

Biological Sciences Faculty Publications

We present findings of a mixed methods study examining the perceptions of students’ (with and without disabilities) understanding and engagement with multimodal STEM text sets. Exit slip and survey data were used to identify areas for improvement in the development of the multimodal STEM text sets for middle school students. Data were collected from 434 middle school students, 86 of whom had a disability, from six teachers’ classrooms in Spring 2021. Significant differences in perceptions of understanding of argumentation were reported between students with and without disabilities. However, ratings of the lessons and the quality of learning, as well as …

The Impact Of Study Strategies On Knowledge Growth And Summative Exam Performance In The First Year Of Medical School, Markia Black, William L. Romine, Molly Simonis, Jeffrey L. Peters, Volker Bahn, Amber Todd

Biological Sciences Faculty Publications

Although the distinction between deep and surface processing strategies, their potential to differentially impact learning, and data supporting the superiority of deep processing strategies on summative exam scores are well supported by the literature, more work is needed to understand: (1) how medical students combine study strategies into learning practices, and (2) the effectiveness of these learning practices in facilitating knowledge gains as measured by standardized test scores.

Vital Signs, Spring 2023, Boonshoft School Of Medicine

Vital Signs

A nine page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Measuring Claim-Evidence-Reasoning Using Scenario-Based Assessments Grounded In Real-World Issues, William L. Romine, Amy Lannin, Ankita Agarwal, Maha Kareem, Emily Burwell

Biological Sciences Faculty Publications

Improving students’ use of argumentation is front and center in the increasing emphasis on scientific practice in K-12 Science and STEM programs. We explore the construct validity of scenario-based assessments of claim-evidence-reasoning (CER) and the structure of the CER construct with respect to a learning progression framework. We also seek to understand how middle school students progress. Establishing the purpose of an argument is a competency that a majority of middle school students meet, whereas quantitative reasoning is the most difficult, and the Rasch model indicates that the competencies form a unidimensional hierarchy of skills. We also find no evidence …