Medicine and Health Sciences Commons^™

Never In A Vacuum: Learning From The Thai Fight Against Hiv, Sean C. Clark

William & Mary Journal of Race, Gender, and Social Justice

No abstract provided.

Proptosis Of Eye: An Atypical Presentation Of Prostatic Malignancy., Amna Amjad, Asif Husain Osmani, Ghulam H

Section of Pulmonary & Critical Care

Orbital metastasis is a rare occurrence found only in about 3 - 10% of all prostate cancers. A 72 years male presented with proptosis of the left eye associated with pain, blurred vision and frequent headaches for the past 8 months. Past medical history had symptoms of bladder outflow obstruction for 3 years. MRI brain and orbit with contrast was consistent with a large soft tissue mass in the left frontal region. The mass was surgically excised in order to achieve palliation. Histopathology revealed poorly differentiated malignant neoplasm with immunohistochemistry favoring metastatic prostate carcinoma. Postoperative radiotherapy was administered with a …

The Physiological And Psychological Effects Of Resistance Training On Overweight And Obese Adolescents, Imara A. Person

Honors Undergraduate Theses

The purpose of this study is evaluating the relationship between resistance training and its effects on obese adolescents with the purpose of reducing physical inactivity. One method includes improving strength in obese children through strength exercises. As well as the effectiveness of resistance training on psychological components such as self-efficacy, exercise competence, and self-esteem as a means of increasing long term exercise adherence.

Research included in this study follow the CDC’s recommendation of youth strength training: 6-17 years old (2022e). Databases such University of Central Florida Library, PubMed, SportDiscus, and Journal of Strength and Conditioning were used to find appropriate …

An Investigation In The Treatment Of Anisometropia With Orthokeratology Lenses, Cara Finn

Student Theses, Dissertations and Capstones

Purpose: The purpose of this study is to evaluate the treatment and management of anisometropia with orthokeratology lenses compared to traditional spectacle lenses. The present study aimed to quantify the interocular difference in relative corneal refractive power shift and examine its association with the differential axial growth.

Methods: One hundred and two subjects between the ages 8 and 14 years old with over -0.50D of myopia and at least 1D of anisometropia were treated with either orthokeratology lenses or traditional single vision spectacle lenses. Baseline data of axial length, refraction, and corneal topography were taken at the initial visit and …

Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses, Catherine M. Crosby, William E. Matchett, Stephanie S. Anguiano-Zarate, Christopher A. Parks, Eric A. Weaver, Larry R. Pease, Richard J. Webby, Michael A. Barry

Nebraska Center for Virology: Faculty Publications

Head-to-head comparisons of conventional influenza vaccines with adenovirus (Ad) gene-based vaccines demonstrated that these viral vectors can mediate more potent protection against influenza virus infection in animal models. In most cases, Ad vaccines are engineered to be replication-defective (RD-Ad) vectors. In contrast, replication-competent Ad (RC-Ad) vaccines are markedly more potent but risk causing adenovirus diseases in vaccine recipients and health care workers. To harness antigen gene replication but avoid production of infectious virions, we developed “single-cycle” adenovirus (SC-Ad) vectors. Previous work demonstrated that SC-Ads amplify transgene expression 100-fold and produce markedly stronger and more persistent immune responses than RD-Ad vectors …