Medicine and Health Sciences Commons^™

Practical Anticonvulasant Pharmacokinetics, R.B. David, L.K. Garrettson

MCV/Q, Medical College of Virginia Quarterly

Pharmacokinetics is that area of pharmacology concerned with the absorption, distribution, metabolism, and elimination of drugs. The processes by which absorption, distribution, and elimination take place are referred to as unit processes. These occur independently and concurrently, and involve such activities as absorption into the blood, elimination from the blood, distribution between the blood and tissue, inactivation in tissues, and finally, elimination from the blood. Drug handling by the body can be characterized by the rate for each step or, more often, the rate of all processes. Classification of observed kinetics for these rate processes includes first-order, zero-order, and capacity-limited …

Radical Reconstruction Of Complex Cranio-Orbito-Facial Abnormalities, John A. Jane, Milton T. Edgerton

MCV/Q, Medical College of Virginia Quarterly

Excellent cosmetic results can be obtained by early intervention in severe cranial-orbital-facial deformity. This intervention should take the form of a combined intracranial and extracranial approach. While the procedure is of great magnitude, the benefits to the patient and to the family seem worth the risk.

Synapsis: Philadelphia Campus (1974), Philadelphia College Of Osteopathic Medicine

All Yearbooks

The 1974 Synapsis includes Neonatology Society, Bariatric Society, Radiology Club, Ear, Nose and Throat Club, E.N.T. Club, Orthopedic Society, Dermatology Society, Dermatology Society, Proctology Club, Anatomy Club, Physiological Chemistry Society, Microbiology Club, Surgery Society, Anesthesia Club, Ob-Gyn Society, Obstetrics and Gynecology Society, Obstetrics and Gynecology, Pediatric Society, Pediatrics Society, Others Interested in Anesthesia, Psychiatric Society, Cranial Manipulation Society, Papanicalou Society, Honor Society, Thoracic Society, Student Osteopathic Medical Association, SOMA, Student American Osteopathic Association, Student A.O.A., Undergraduate Academy of Applied Osteopathy, Atlas Club, Iota Tau Sigma, ITS, (ΙΤΣ), Lambda Omicron Gamma, LOG, (ΛΟΓ), Phi Sigma Gamma, PSG, (ΦΣΓ), Student Wives Club, …

Modern Immunology: Cells And Molecules, Franklin Mullinax

MCV/Q, Medical College of Virginia Quarterly

In this presentation I shall discuss 1) some historical highlights n the field of immunology; 2) the molecules of immunity, particularly the immunoglobulins; and 3) the cells of immunity, particularly the immunocytes. This presentation may provide a background for subsequent articles.

Training Workout Log Book Spring 1966-1974, Edward S. Temple

Temple Training Workout Log Books

No abstract provided.

Surgical Care Of The Lower Extremity In Rheumatoid Arthritis, Roby C. Thompson

MCV/Q, Medical College of Virginia Quarterly

One of the most important things for the physician to recognize in referring a patient to the orthopedic surgeon for treatment of rheumatoid arthritis is the goal of surgical correction. The primary goal in surgical treatment of diseased joints in the lower extremity is relief of pain. Some pain-free patients have such severe deformities that a surgical procedure may be undertaken in order to improve and restore function, accepting certain calculated risks; however, to improve function surgically in a pain-free joint requires complete and full understanding on the part of the patient as well as the physician.

Introduction, Robert Irby

MCV/Q, Medical College of Virginia Quarterly

The 45th Annual McGuire Lecture Series has been devoted to the subject of Immunology and the Rheumatic Diseases. In this two-day period, 22 outstanding physicians in the field of immunology and rheumatology brought an up-to-date overall concept in the field of rheumatic diseases. Subjects included not only aspects of pathogenesis but also modern laboratory methods in the diagnosis of various connective tissues diseases. The remedial surgical approaches for prevention of pain and disability in rheumatoid arthritis were discussed from a practical viewpoint.

Recent Advances In Synovial Fluid Analysis, Duncan S. Owen Jr.

MCV/Q, Medical College of Virginia Quarterly

Synovial fluid analysis is a frequently ignored examination except in suspected cases of septic conditions. It has been shown that it is an extremely valuable procedure in making rapid and accurate diagnoses in many types of joint diseases.

A Review Of Some Aspects Of L-Forms And Gonococci, Charles L. Cooke, Bernard Germain, Bonnie Balducci, Harry P. Dalton

MCV/Q, Medical College of Virginia Quarterly

Systemic manifestations of gonococcal disease, such as arthritis, are often sterile on the usual culture methods used to grow gonococci. Allergic mechanisms have been invoked to explain this but with little evidence to support the concept. With the report by Holmes et al., that L-forms of gonococci were isolated from joint fluid of a patient with gonococcal arthritis, we decided to investigate the possible role of L-forms in gonococcal disease.

Introduction, Donald P. Becker

MCV/Q, Medical College of Virginia Quarterly

Recently, important strides have been made in clinical neurology and clinical neurosurgery, culminating in improved patient care. The last ten years have witnessed a new sophistication in neuroradiology, and the clear development of neuroophthalmology as a subspecialty. It is to these areas that the speakers at the 27th Stoneburner Lecture Series addressed themselves. The first part of the program emphasized cerebral vascular disease, and is presented in this issue. The second part of the program related primarily to the clinical care of patients with mechanical brain injury, brain tumors, and seizures, and will be presented in the following issue of …

Immune Complex Reactions In Systemic Lupus Erythematosus, John Staige Davis Iv

MCV/Q, Medical College of Virginia Quarterly

We should first try to define systemic lupus erythematosus (SLE). Table 1 lists criteria proposed by a committee of the American Rheumatism Association. If four of these 14 major criteria are positive, then there should be about 98% specificity for SLE. There are clearly many facets to this disorder. Let us consider mechanisms that might account for a multisystem disease such as this.

Anklylosing Spondylitis, John Baum

MCV/Q, Medical College of Virginia Quarterly

Within the last few years, the study of ankylosing spondylitis has produced some of the more remarkable new developments in the field of the rheumatic diseases. In modern days the disease has been described in Germany by Strümpell and in France by Marie. As a result, in Germany it is known as Strümpell's disease and in France as Marie's disease. Physicians in the United States and England, to be fair, call it Marie-Strümpell disease. It should be emphasized at this point that ankylosing spondylitis is not a variant of rheumatoid arthritis as it had been considered for a number of …

The Interrelationship Of Intracranial Pressure, Cerebral Blood Flow, And Brain Metabolism In Experimental Brain Injury, Thomas W. Langfitt

MCV/Q, Medical College of Virginia Quarterly

This presentation will be concerned with some of the relationships between intracranial pressure, cerebral blood flow, and brain metabolism as defined in animal models. We will also be concerned with the pathophysiological changes that occur among these numerous variables.

Chromosome Abnormalities And Repeated Abortion: A Preliminary Report, Susan English, Deborah W. Heritage, Andrew T. L. Chen, Reuben B. Young

MCV/Q, Medical College of Virginia Quarterly

In view of the increased frequency of chromosome rearrangements demonstrated in these couples and the importance of counseling for future pregnancies, it would be wise to consider cytogenetic evaluation when all other probable causes for recurrent abortion have been ruled out.

Reconstructive Intracranial Vascular Surgery, John M. Tew Jr.

MCV/Q, Medical College of Virginia Quarterly

It is scarcely less than two decades since the initial cautious explorations of reconstructive surgery for the prevention of cerebral infarction caused by extracranial vascular disease began. The next years recorded an accumulative experience in the field of vascular surgery. Early clinical investigations led to the discovery that extracranial vascular disease is a major cause of cerebral infarction or stroke. Estimates indicate, however, that only 30-40% of the patients with cerebrovascular insufficiency have significant extracranial occlusive disease. For this larger group of patients, previous surgical methods offer no hope. It is the purpose of this report to review the current …

Advances In The Management Of Pituitary Tumors, Charles B. Wilson

MCV/Q, Medical College of Virginia Quarterly

A new development in the management of pituitary tumors is the transsphenoidal technique. It will be my purpose to show that it provides an elegant way of handling the great majority of pituitary problems, at least the ones that I have encountered, although it has its shortcomings as well as its advantages.

Advances In The Medical And Surgical Management Of Intractable Partial Complex Seizures, Hooshang Hooshmand

MCV/Q, Medical College of Virginia Quarterly

Seizures can be due to a variety of acute, subacute, or chronic diseases with different etiologies. Clinically, they may manifest as focal or generalized phenomena. Whereas the majority of the patients suffering from partial seizures are easily controlled with medications, in a small number of patients treatment may fail. The failure may be due to incorrect diagnosis or incorrect therapy. The efficacy of medical treatment for seizure disorder depends upon six factors: 1) dosage; 2) the size of the patient; 3) drug interaction; 4) drug specificity for the disease; 5) the nature of the disease for which the drug is …

Advances In The Treatment Of Patients With Benign Brain Tumors, Harold F. Young

MCV/Q, Medical College of Virginia Quarterly

Reliable ICP measurement allows an exact quantitation and management of intracranial pressure. This precise assessment of ICP is a valuable adjunct in the management of anesthesia for brain tumor patients. The proper combination of ICP and anesthesia management enables the surgeon to use the operating microscope to approach previously inaccessible areas of the brain and to perform meticulous surgery with a better prognosis for the brain tumor patient.

Progress And Problems In The Rehabilitation Of Patients With Central Nervous System Injuries, L.D. Amick

MCV/Q, Medical College of Virginia Quarterly

Let us briefly consider the general nature of contemporary rehabilitation with highlights of its progress and problems. Paraplegia and hemiparesis may be thought of as the models of neurologic impairment.

Advances In Neuroradiology, Frederick S. Vines, Charles Bonstelle

MCV/Q, Medical College of Virginia Quarterly

The development of two new radiological techniques has significantly enhanced the performance of neuroradiological diagnostic procedures. The first of these was installed as the prototype unit at the Medical College of Virginia in November of 1972 and has marked advantages for the performance of encephalography, angiography, and air myelography. The present communication will relate the experiences of the author during the initial 15 months of clinical evaluation. The second technique is an entirely new concept of obtaining further information from the data provided by the penetration of x-ray photons. Each of these units will be discussed briefly with an outline …

Cerebral Blood Flow Studies In Stroke, John Stirling Meyer

MCV/Q, Medical College of Virginia Quarterly

This consideration of the relationship of neuro-transmitters not only to cerebral infarction but also to subarachnoid hemorrhage is, to my mind, the most promising area of investigation over the next decade. There is also a quantity of evidence that neurotransmitters play a large part in spasm following subarachnoid hemorrhage and in the disturbance of neurological function in that situation. Following subarachnoid hemorrhage, some remediable medical problems arise. Apart from clipping of the aneurysm, which the neurosurgeons are able to do, there is the problem of communicating hydrocephalus, which is extremely common in about 40% of patients. It can be discerned …

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1974, Volume Ten, Number Two.

Clinical Advances In The Diagnosis Of Cerebral Vascular Disease, John Stirling Meyer

MCV/Q, Medical College of Virginia Quarterly

I have chosen some thoughts about recent clinical advances in the diagnosis of cerebral vascular disease, which I feel are appropriate for this paper, confining my discussion to the signs, symptoms, natural history, and risk factors of cerebral vascular disease.

Table Of Contents, Volume Ten, 1974.

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1974, Volume Ten.

Genetic-Metabolic News

MCV/Q, Medical College of Virginia Quarterly

One of the primary aims of the genetic counselor is the reduction in the number of children born with either lethal disorders or severe CNS dysfunction (eg. Mongolism and midline neural defects). Generally, this goal is accomplished in one of four major ways.

Alumnae Association Bulletin Of The School Of Nursing, 1974, Margaret Summers, Doris E. Bowman, Charlotte E. Voss, Mabel C. Prevost, Carol Hutelmyer, Francis J. Sweeney, Laird Jackson, Janet Hindson, Deidre Watkins Blank, Jeanette Plasterer, Lenora W. Schwartz, Martha E. Riland, Rosa Diserode

Nursing Alumni Bulletins

Alumnae Calendar

The President's Message

Officers and Chairmen of Committees

Financial Report

Annual Reports

Trends in Nursing

College of Allied Health Sciences - Sesquicentennial Symposium

Clinical Teaching Facility

Genetic Counseling Program at Jefferson

Dr. Laird Jackson, M.D.

Breast Diagnostic Program

Prof. John D. Wallace with Marciarose and Tony Landess, The KYW Noon News Team

Committee Reports

Annual Luncheon

Administration

Missing Alumnae Members

Salute to Life Members

Model Showing Site of New Clinical Teaching Facility

Resume of Minutes of Alumnae Association Meetings

"Mr. Brown" The Weatherman

The Class of 1924

Ways and Means Committee Report

Class News

In Memoriam

Marriages

Births …

Front Matter, Vol. 19 No. 1

Brigham Young University Science Bulletin, Biological Series

No abstract provided.

Surgery In Rheumatoid Arthritis: General Indications And Philosophic Considerations, R. S. Bryan

MCV/Q, Medical College of Virginia Quarterly

In summary, orthopedic surgery has much to offer the rheumatoid patient, particularly if the proper patient is chosen at the proper time. The advent of the total joint replacements, now in its infancy, gives renewed hope for the salvage of many derelicts and for the prevention of the severe disabilities and deformities which were all too frequent in the past.

Introduction, Robert Irby

MCV/Q, Medical College of Virginia Quarterly

This issue of the MCV/Q is a continuation of the first issue of this year, which was devoted to the subject of Immunology and the Rheumatic Diseases. Many of the papers presented at the 45th Annual McGuire Lecture Series were published in the first issue and this will complete those papers which were submitted for publication.

Histocompatibility Antigens And Spondylitis, Robert Irby, William Edwards, James Pierce, Roderick Macdonald

MCV/Q, Medical College of Virginia Quarterly

This is a transcript of a discussion about HL-A antigens and spondylitis at Medical Grand Rounds by the Department of Medicine, Surgery, and Ophthalmology on January 29, 1974, at the Medical College of Virginia, Richmond.