Medicine and Health Sciences Commons^™

Prevalence And Determinants Of Metabolic Syndrome Among Adults Attending Primary Health Care Centers In Baghdad: A Cross-Sectional Study, Muammar Basheer Yasir, Almottesembellah Abdalruhman Gaiz, Noor Abdulredha Jaleel

Al-Esraa University College Journal for Medical Sciences

Metabolic syndrome has emerged as an important health concern globally, especially in developing countries where urbanization and lifestyle changes are rapidly increasing. No reliable epidemiological information regarding the prevalence and risk factors associated with metabolic syndrome is available among Iraqi adults in primary health care (PHC) clinics. This study was designed to determine the prevalence rate of metabolic syndrome and identify potential risk factors among adults attending PHC centers in Baghdad. Methods: An analytical cross-sectional study design was used, targeting 412 adult subjects selected randomly from multiple PHC centers in Baghdad. Sociodemographic, lifestyle, anthropometric, and biochemical data were collected. The …

Determination The Prevalence Of Multidrug Antimicrobial Resistance Of Nosocomial Enterobacter Cloacae Isolates From Clinical Specimens In Baghdad Hospitals, Baidaa Mijbel Ali

Al-Esraa University College Journal for Medical Sciences

Background: Enterobacter cloacae have challenged global health through nosocomial infections, especially among immunocompromised patients. In the most overburdened healthcare systems, more study and strategy are anticipated. Aim of the study: To determine the prevalence of Enterobacter cloacae in hospital-acquired infections in Baghdad hospitals and to evaluate its antimicrobial resistance patterns across burn, wound, and urine samples, with a focus on multidrug resistance and antibiotic resistance trends. Methods: Three hundred and seventy-seven patient samples were collected and examined at a teaching laboratory in Baghdad between January 2024 and December 2024. These had 513 samples, 238 burn swabs, 139 wound swabs, and …

The Association Between Osteoporosis In Females Following Menopause And Vitamin D Deficiency, Hadel Kareem Al-Rubaiawi, Noor Adel Hussein, Dunia Abdul Jabbar Star, Amer Hasan Abdullah, Salma Abdul-Ridha Abbas, Hawazin Aziz Hamim

Al-Esraa University College Journal for Medical Sciences

The intricate relationship among osteoporosis, vitamin D deficiency, and hormonal changes. Growth hormone, cortisol, parathyroid hormone, estrogen, testosterone, thyroid hormones, and thyroid hormones are a few of the hormones that affect bone turnover and density. Alterations in their concentrations, whether brought on by healthy aging or illnesses, can interfere with bone remodelling and increase the risk of osteoporosis. Moreover, inadequate levels of vitamin D increase the risk by decreasing the absorption of calcium and the mineralization of bone. Estrogen and vitamin D deficits increase bone loss, especially in postmenopausal women. Proactive treatment techniques, including hormone replacement therapy, vitamin D supplements, …

Reinforcement Of Maxillofacial Silicone, Taqwa Majid Abdulhussein, Thekra Ismael Hamad

Al-Esraa University College Journal for Medical Sciences

Maxillofacial prostheses are very important for helping people with head and neck defects (caused by congenital disabilities, accidents, or cancer treatments) get better. Their goal is to restore oral function, comfort, appearance, and mental health. Since the 1960s, silicone elastomers, especially polydimethylsiloxane, have been considered the best materials because they are highly resistant to tearing and stretching, biocompatible, and naturally colour-stable, but silicone has a very short clinical lifespan because it breaks down when exposed to UV radiation, moisture, biological fluids, and mechanical stress. The main goal of reinforcement is to add fillers to silicone elastomers to strengthen and improve …

Organic Coumarin Derivatives As Laser-Active Materials: A Review Of Synthesis, Optical Behaviour, And Applications, Aya H. Mohammed, Mohammed Hasan Al-Dahlaki

Al-Esraa University College Journal for Medical Sciences

Coumarin derivatives have settled into a position of unusual prominence among organic laser-active materials. Few other chromophore families combine such favourable photophysics with synthetic chemistry that is at once long-established and still actively evolving. The aim of this review is to draw together what is now known about coumarin-based laser dyes — their preparation, their optical behaviour, the laser performance that has been achieved with them, and the broader applications that have followed — with particular attention to work published between 2019 and 2026. Considerable space is given to the structural origin of the strong intramolecular charge transfer (ICT) character …

Risk-Based Nurse-Managed Personalized Heart Failure Interventions: The Alleviate-Hf Trial., Javed Butler, Rami Kahwash, Muhammad Shahzeb Khan, David Zhang, Jonathan W Dukes, Madhu Reddy, Anupam Basuray, Elie Gharib, Bart Gerritse, Aimee Laechelt, Jennifer Wehking, Shantanu Sarkar, Brian Van Dorn, Nirav Patel, Verla Laager, Michael R Zile, Alleviate-Hf Investigators

Heart and Vascular Articles

BACKGROUND: Early identification of worsening heart failure (HF) may improve outcomes.

OBJECTIVES: This study aims to assess if insertable cardiac monitor (ICM)-based high-risk detection combined with centrally managed, nurse-facilitated, individually protocolized diuretic interventions is safe and improves HF outcomes.

METHODS: A Reveal LINQ (Medtronic) ICM with an investigational HF risk-status software was implanted in participants with HF who were randomized 1:1 to an intervention arm (high-risk HF alert triggering protocolized diuretic regimen) or an observation arm (standard care). The primary safety endpoint was intervention-related serious adverse events and the primary efficacy endpoint was a 5-component hierarchical composite including cardiovascular death …

Analysis Of Priority Vaccine-Preventable Diseases Using The Paho-Adapted Hanlon Method In Bogor City In 2024, Sonia Annisa Br Ketaren, Tri Yunis Miko Wahyono, Bai Kusnadi

Jurnal Epidemiologi Kesehatan Indonesia

Vaccine-preventable diseases (VPDs) remain a major public health challenge despite substantial progress in immunization programs. In Indonesia, routine immunization coverage has shown a post-pandemic recovery trend; however, disparities in access to health services and surveillance quality persist across regions. This study aimed to determine priority VPD problems in Bogor City and identify factors contributing to the highest-ranked disease. A mixed-methods study was conducted in Bogor City from October 2024 to January 2025. Quantitative prioritization was performed using the Pan American Health Organization (PAHO)-adapted Hanlon method across eight VPDs. Qualitative data were collected through in-depth interviews with key informants and analyzed …

The Effect Of The Lee Silverman Voice Treatment (Lsvt) Big Method Based On Occupation On Older Adult Functional Mobility Balance, Muhammad Luthfi, Kharisma Nur Idalasari

Jurnal Fisioterapi Terapan Indonesia

Balance impairment is one of the major problems commonly experienced by older adults as a result of degenerative processes, leading to an increased risk of falls. Falls may cause fear of recurrent falling, reduced physical activity, loss of physical capability, and may eventually result in disability and psychological consequences such as depression. Structured, occupation-based physical activity has been shown to provide various benefits for older adults, including improving physical function, slowing functional decline associated with degenerative processes, reducing fall risk, and enhancing postural control. This study aimed to analyze the effect of the occupation-based Lee Silverman Voice Treatment (LSVT) BIG …

Role Of Mcp-1 Serum Level Along With Its Genetic Polymorphism In Open-Angle Glaucoma Disease Susceptibility, Ahmed. A. Cashmosh

Al-Qadisiyah Medical Journal

Background: The chronic optic neuropathy known as slowly developing primary open-angle glaucoma (P.O.A.G.) is typified by unique patterns for optic nerve degeneration as well as vision field loss. is the most prevalent kind, a complicated, multidimensional illness with a pathophysiology influenced by both genetic and environmental variables. Objective: This study's objective is to find the relation between polymorphism of the MCP-1 gene with open-angle glaucoma disease susceptibility along with their proposed role in disease pathogenesis. Materials and Methods: Two groups were the subjects of a case-control study: The first group included 40 patients who had previously been diagnosed with glaucoma, …

Objective Biomarker Development For Parameter Optimization In Neuromodulation Using High-Density Emg Temporal And Spatial Features, Shirin Madarshahian, Nikoo Javadpour, Michael Trakhtorchuck, Tatiana Guerrero-David, Kristin Gustafson, James Harrop, Caio Matias, M. J. Mulcahey, Alessandro Naopli, Alex R. Vaccaro, Mijail Serruya

Farber Institute for Neuroscience Faculty Papers

Transcutaneous spinal cord stimulation (tSCS) is a promising neuromodulation approach for motor recovery after spinal cord injury (SCI), yet clinical programming remains largely dependent on subjective parameter selection. This study evaluated high-density surface EMG (HD-sEMG)–derived spatial and temporal features as objective biomarkers for tSCS optimization in three adults with chronic cervical SCI. A 64-channel electrode array recorded stimulation-evoked responses across five cervical stimulation levels, four pulse widths, and graded amplitudes. Features describing activation magnitude, spatial distribution, cluster morphology, and temporal dynamics were extracted from epoch-based activation maps. Of the three enrolled participants, two demonstrated measurable stimulation-evoked responses and contributed to …

Fractionated Stereotactic Radiotherapy (Fsrt) For Symptomatic Who Grade 1 Cavernous Sinus Meningiomas: Long-Term Local Control, Clinical Response, And Toxicity Outcomes, Ryan Shah, Shray Jain, Nilanjan Haldar, Lauren A. Holt, Robert Walker, Christopher J Farrell, Md, Debanjan Haldar, James J. Evans, Gregory S. Alexander, Wenyin Shi

Department of Radiation Oncology Faculty Papers

PURPOSE: Cavernous sinus meningiomas represent a significant clinical challenge, given the high prevalence of neurological deficits and limited surgical options. Radiation therapy is often the preferred treatment. This study evaluates the effectiveness of fractionated stereotactic radiation therapy (fSRT) in achieving local control and symptomatic relief in patients with cavernous sinus meningiomas.

METHODS: This is a single-institution retrospective analysis of patients with symptomatic presumed WHO grade 1 cavernous sinus meningiomas treated with fSRT (1.8-2 Gy per fraction). Clinical data were collected by chart review. Kaplan-Meier curves were generated to assess local control. Clinical responses were evaluated for symptom improvement, stability, or …

Waste Analysis Of Outpatient Waiting Time In The Obstetrics And Gynecology Polyclinic (Ob-Gyn) On Lean Healthcare Approach At X General Hospital Jember, Widian Almas Zatin, Dwi Prijatmoko, Firman Firman

Preventia: The Indonesian Journal of Public Health

In outpatient services, waiting time is one indicator of the quality of hospital services and can influence patient satisfaction. The research aims to analyze the waste of outpatient waiting time at the OB-GYN polyclinic of X General Hospital, Jember, using a lean healthcare approach. The case study for this research used a mixed-methods exploratory sequential design. Data were collected through observation, structured interviews, reviewing the standard operating procedures and the service flow, and distributing questionnaires to identify critical waste. The sequence of services was analyzed using Value Stream Mapping to identify value-added, non-value-added, and waste. Process Cycle Efficiency (PCE) was …

Intimate Partner Violence And Adverse Pregnancy Outcomes Among Women Accessing Postnatal Care In A Tertiary Hospital In North-Central Nigeria: A Cross-Sectional Study, Paul E. Agbo, Lucky L. Changkat, Mary C. Momoh, Salihu O. Mohammed, Dogara B. Bawa, Adeola Olabamiji, Rashida Musa, Steve C. Okoro, Ene F. Agbo, Lawal A. Abdulmumuni

Preventia: The Indonesian Journal of Public Health

Intimate partner violence (IPV) during pregnancy is a major public health concern associated with adverse maternal and neonatal outcomes, particularly in low- and middle-income countries. Despite increasing recognition, evidence linking specific forms of IPV to pregnancy outcomes in Nigeria remains limited. This study was conducted to determine the prevalence of intimate partner violence and examine its association with adverse pregnancy outcomes among women attending postnatal care in a tertiary hospital in North-Central Nigeria. A hospital-based cross-sectional analytic study was conducted among 381 women attending postnatal care. Data were collected using a structured, interviewer-administered questionnaire that incorporated the Abuse Assessment Screen. …

Association Of Lifestyle, Nutritional Status, And Eating Habits With Academic Performance Among Adolescents, Lulu'ul Badriyah, Farah Paramita, Rachmy Rosyida Ro'is, Shanica Yohana Veronica, Alifia Meida Indrayati, Randy Gustawan

Preventia: The Indonesian Journal of Public Health

Health is an important factor in determining academic performance. This study aims to analyze the relationships between lifestyle, nutritional status, eating habits, and academic achievement among high school students. The study used a cross-sectional design with a sample of 131 students from four schools in Malang City, Malang Regency, Batu City, and Pasuruan Regency. Data were collected through interviews, anthropometric measurements, and the SQ-FFQ and IPAQ questionnaires. Analysis was performed using the Chi-Square test. The results showed that most respondents slept less than 8 hours (58.8%), used smartphones for ≥ 8 hours per day (50.4%), had moderate physical activity (52.7%), …

Respectful Maternity Care: A Narrative Review Of Current Evidence And Clinical Implications, Hadeel Rasheed Seger, Nada Abd Ali Mohammed, Khalid Alyodawi

Preventia: The Indonesian Journal of Public Health

Respectful Maternity Care (RMC) is key to improving quality maternity care and has also been recognized as a foundational approach to quality maternity services. The framework has been developed around respect and promotion of dignified care, confidentiality and privacy, and autonomy of a woman, along with her right to freedom from neglect, discrimination, physical and verbal abuse, during pregnancy and childbirth. Despite worldwide acknowledgment and promotion of RMC, disrespect and abuse during childbirth have been observed among women in maternity settings, especially in low- and middle-income countries. This narrative review summarizes the current evidence and clinical implications of RMC. The …

Kmt2d As An Epigenetic Target In Cervical Cancer: A Literature Review On Polyclonal Antibody Therapeutics And Translational Prospects, Farsya Hidayah Septiananda, Taurisma Aulia Nanda Wibisono, Rajendra Aulya Gilardino, Andreas Budi Wijaya

Preventia: The Indonesian Journal of Public Health

Cervical cancer remains a significant global health burden, particularly in regions with limited access to advanced therapeutics. Beyond viral oncogenesis, accumulating evidence highlights the crucial role of epigenetic dysregulation, particularly KMT2D, in tumor initiation and progression. This literature review aimed to critically synthesize current evidence regarding the biological role of KMT2D in cervical cancer and to explore the opportunities and limitations of antibody-based approaches for future epigenetic intervention. A structured narrative literature review was conducted using PubMed, Scopus, and Web of Science to identify relevant studies published between January 2020 and May 2025. Literature selection was guided by a modified …

The Effect Of Self-Hypnosis On Self-Efficacy, Anxiety, And Depression In Mothers Of Children With Chronic Kidney Disease, Rohmaningtyas Hidayah Setyaningrum, Mohammad Fanani, I Gusti Bagus Indro Nugroho, Debree Septiawan, Siti Wahyuni, Damar Upahita

Folia Medica Indonesiana

More than half of caregivers of children with chronic kidney disease (CKD) report experiencing moderate depression (53.3%), while 30% and 16.7% report mild and severe depression, respectively. As primary caregivers, mothers require strong self-efficacy to manage psychological burden associated with caring for children with CKD. Self-hypnosis may enhance self-efficacy and alleviate anxiety and depression in this population. The aim of this study was to evaluate the effects of self-hypnosis in improving self-efficacy and reducing anxiety and depression in mothers of children with CKD. A randomized controlled trial was conducted at Dr. Moewardi Hospital, Surakarta, Indonesia. Thirty-two mothers were randomly assigned …

The Effect Of Plyometric Training On Leg Muscle Explosive Power In Adolescent Amateur Volleyball Players, Dany Fajar Muhlasin, Fendy Nugroho, Jasmine Kartiko Pertiwi

Jurnal Fisioterapi Terapan Indonesia

Background: Leg muscle explosive power is a crucial physical component in volleyball, particularly in supporting the execution of smashes and blocks. The ability to generate force rapidly and explosively plays a key role in determining an athlete’s jumping performance. One training method proven effective in enhancing leg muscle explosive power is plyometric exercise. Several recent studies have shown that plyometric training can significantly improve vertical jump performance in adolescent athletes. However, there is still limited research specifically examining the effect of plyometric exercise on jumping explosive power in amateur players aged 14–18 years, indicating a research gap that warrants further …

Pengaruh Rehabilitasi Berbantuan Robot Terhadap Pemulihan Fungsional Setelah Total Hip Arthroplasty: Literature Review, Dian Rahayu Wijayanti, Kholida Nabila, Nadzifa Salsabila Haris Putri, Nur Afrina Azra, Septina Olivia, Farid Rahman

Jurnal Fisioterapi Terapan Indonesia

Total Hip Arthroplasty (THA) remains a gold standard for restoring joint function in patients with severe hip osteoarthritis, yet achieving optimal functional recovery post-surgery remains a challenge. Robot-assisted rehabilitation (RAR) has emerged as a novel physiotherapy modality offering structured, repetitive, and sensor-driven training that may enhance recovery trajectories. Objective: This literature review aims to identify and synthesise current evidence on the effectiveness of RAR in improving functional outcomes after THA, focusing on gait performance, muscle strength, balance, and quality of life. Methods: A comprehensive search of PubMed, PEDro, ScienceDirect and Google Scholar was conducted for peer-reviewed articles published between 2015 …

Community-Based Exercise Programs Dalam Mengurangi Fear Of Falling Dan Meningkatkan Quality Of Life Pada Lansia: A Systematic Literature Review, Amirah Hasna Rafifah -, Hanif Maulana, Saffanah

Jurnal Fisioterapi Terapan Indonesia

The global increase in the elderly population presents significant challenges in maintaining independence and quality of life among older adults. One of the most common problems experienced by the elderly is fear of falling, which negatively affects physical activity, balance, and psychological well-being. Community-based exercise programs represent an approach that not only improves physical function but also strengthens social interaction and self-confidence among older adults. This study aims to review community-based exercise programs in reducing fear of falling and improving quality of life among the elderly through a Systematic Literature Review (SLR) using the PRISMA 2020 guidelines. The literature …

Analisis Perbedaan Pengaruh Mc Kenzie Exercise Dan Post Isometric Relaxation Terhadap Penurunan Nyeri Leher Non Spesifik Pada Remaja, Nabila Ayu Meilya Putri, Saifudin Zuhri, Sugiono -

Jurnal Fisioterapi Terapan Indonesia

Background: The use of laptops and computers has become an essential part of daily life, especially among adolescents. However, the habit of maintaining a static posture for prolonged periods while using these devices often leads to excessive strain on the neck and shoulder muscles. To address these problems, interventions such as Mc Kenzie exercise and post isometric relaxation can be applied. Objective: To determine the difference in the effects of Mc Kenzie exercise and post isometric relaxation on reducing nonspecific neck pain in adolescents. Methods: This study employed a two-group pre and post-test design conducted from June to July 2025 …

A Mathematical Model For Managing Diphtheria Outbreaks In Nigeria Via Vaccination, Enhanced Surveillance, Effective Quarantine, And Social Distancing Measures, Hycienth Ortser Orapine, Nyiutya Cephas Ine, Dekera Jacob Washachi, Ali Audu Baidu, Lubem Matthew Kwaghkor

Mathematical Modelling and Numerical Simulation with Applications

Diphtheria is a highly infectious respiratory and skin disease that poses a significant threat to global public health. In Nigeria, children and adults with low immunity remain at high risk due to recurring annual outbreaks in the last decade, with a death rate of as high as 68.8\%. This paper presents a deterministic compartmental model to evaluate the effectiveness of interventions implemented by the Nigerian government. The model's mathematical and epidemiological validity is established through proofs of non-negativity and boundedness. The basic reproduction number ($R_0$) is derived, and stability analysis confirms that the diphtheria-free equilibrium is locally and globally asymptotically …

Stochastic Analysis Of Epidemic Size And Peak Infection In An Svir Model With Imperfect Vaccine And External Source Of Infection, María Gamboa Pérez

Mathematical Modelling and Numerical Simulation with Applications

The dynamics of an infectious disease outbreak are studied under a stochastic framework in a closed population where individuals are homogeneously mixed. A vaccination program is implemented in the community prior to the start of the epidemic. The administered vaccine is imperfect, meaning that vaccinated individuals may still become infected upon contact with infected individuals. The mathematical Susceptible-Vaccinated-Infected-Recovered (SVIR) model describing the evolution of the epidemic is formulated as an absorbing, continuous-time, three-dimensional Markov chain with compartments for vaccinated, susceptible, infected and recovered individuals. The aim of this study is to characterize two fundamental epidemiological quantities: the maximum number of …

The Prevalence Of Oral Diseases In Heredity Bleeding Disorders In Iraq, Warkaa M. Al-Wattar

Al-Esraa University College Journal for Medical Sciences

Aim: To investigate the effect of bleeding disorder on oral condition in Iraqi patients. Patient and methods: 153 patients were included in this study attending dental unit in Iraqi center of hematology. They were diagnosed and treated for ordinary oral diseases like dental caries and periodontal diseases mainly. While treatment vary from only diagnosis and checkup to more complicated surgical extraction. The patients data include sex, blood group, cheife complain and type of treatment. Results: The main chief complain was dental caries and less periodontal diseases while main treatment management was only checkup. The blood group O was the most …

Association Between Body Mass Index, Vitamin D3 And Lipid Profile In Type 2 Diabetes Mellitus, Eman Ali Hussein, Hulia Kanan Mohammed, Zainab Abduljabbar Ridha Al-Ali, Qater Alnada Jassim Mohammed, Alaa Al-Noori, Tarik Muhammad Ali, Noor Thair Tahir

Al-Esraa University College Journal for Medical Sciences

Dyslipidemia and vitamin D Deficiency are one of the most common disorders among type 2 DM patients, this study was conducted to investigate in the relationship between lipid profile and vitamin D status and body mass index (BMI) Among DM patients in Baghdad province / Iraq. study was madeon 120 subjects (diabetic as well non diabetic). The fasting blood glucose (FBG) levels, glycated HbA1c), lipid profile including total cholesterol, triglycerides, LDL, HDL andVLDL levels and serum vitamin D level were analyzed. Current study observied that the values for FBG, HbA1c, insulin, HOMOIR, TC, TG, HDL, LDL, VLDL, and Vitamin D, …

Effect Of High Protein Diets On Kidney Health Among Athletes And Bodybuilders With Normal Kidney Function, Mustafa Mehdi Alqazzaz, Sajad Abdullah Jleep, Nouran Hussein Mutlaq, Ali Jabbar Jassem

Al-Esraa University College Journal for Medical Sciences

This study emphasizes the effect of high-protein diets(HPD) on kidney function, focusing on key biomarkers (Albumin, Urea, Creatinine & GFR). A HPD is defined as a protein consumption >1.5g/kg per day. Results indicated variations in certain biomarkers among the participants (healthy athletes & bodybuilders with normal kidney function) suggesting potential changes in renal workload. Many studies in resistance-trained athletes focusing at HPD, concluded that there are no harmful effects of HPD on renal health. While no immediate kidney damage was observed, we suggest further investigation into the long -term implications of HPD, particularly for individuals with specific health conditions.

Atracurium And Rocuronium On Pain Score During Intravenous Injection, Suha Adel Qasim Al-Ani

Al-Esraa University College Journal for Medical Sciences

Background: The non-depolarizing muscle relaxant (NDMR) is generally used in anesthesia for facilitation of intubations and muscle relaxations. Nevertheless, pains during injections remain as significant concerns. Aim of the Study: The aim of the study was to compare levels of pain scores related to various types of NDMR (Atracurium and Rocuronium) during injections. Patients and Methods: This study was applied on (60) patients whose ages ranged between (18–65) years and underwent different surgical operations. Patients are categorized into two groups: (31) patients receiving IV Atracurium and (29) receiving Esmeron (Rocuronium) in different doses. Following IV injection of the drug, immediate …

Epidemiology, Classification, Risk Factors, Pathophysiology And Management Of Diabetes Mellitus: A Review, Mohammed Raad Khalaf, Tariq Muhammed Ali, Entedhar K. Hussain, Alaa Al-Noori

Al-Esraa University College Journal for Medical Sciences

Diabetes mellitus is a common metabolic disorder, remains a global health challenge with escalating prevalence rates, necessitating a thorough understanding of its multifaceted aspects for effective management. This review synthesizes current knowledge on the epidemiology, classification, risk factors, pathophysiology, and management strategies of diabetes. The epidemiology highlights the rising global prevalence of DM and its regional variations, emphasizing the socio-economic and demographic factors contributing to this epidemic. The classification provides an in-depth analysis of the evolving classification systems, encompassing Type 1, Type 2, and gestational diabetes. Risk factors associated with the development of diabetes are explored, encompassing genetic predisposition, lifestyle …

The Pivotal Role Of Artificial Intelligence In Optimizing Pharmaceutical Formulation And Delivery, Ali Khidher Abbas, Mustafa M. Noori, Ibtihal Abdulkadhim Dakhil, Mohammed Hussain Al-Mayahy

Al-Esraa University College Journal for Medical Sciences

Artificial intelligence (AI) has emerged as a transformative technological paradigm within the pharmaceutical sciences, offering innovative and forward-looking solutions to surmount the inherent limitations associated with conventional drug development, formulation design, and therapeutic delivery systems. Traditional pharmaceutical methodologies frequently entail protracted development timelines, extensive experimental procedures, and substantial financial expenditures, particularly within the domains of formulation optimization and drug delivery design. The integration of AI-driven technologies – encompassing machine learning (ML), deep learning (DL), artificial neural networks (ANNs), and predictive analytics – has considerably accelerated pharmaceutical research by refining decision-making processes, alleviating experimental burden, and enhancing formulation efficiency. The present …

The Pathological Interaction Between Diabetes And Hypertension: Mechanisms And Clinical Complications, Alaa Al-Noori, Ayad Ahmed Al-Taweel, Qater Alnada Jassim Mohammed, Tarik Muhammad Ali, Majeed Mihsin B. Al-Hamdani, Noor Thair Tahir

Al-Esraa University College Journal for Medical Sciences

Among the most prevalent chronic conditions, diabetes and hypertension frequently coexist in a single patient, aggravating vascular problems and hastening the deterioration of target organs, especially the kidneys. By raising intraglomerular pressure, impairing endothelial function, and triggering oxidative stress and inflammation, hypertension directly increases the chance of developing diabetes sequelae, including diabetic nephropathy. Chronic kidney disease advances more quickly when poorly managed hyperglycemia and hypertension combine to cause a decrease in glomerular filtration rate and an increase in urine albumin excretion. Other consequences like retinopathy, neuropathy, and cardiovascular disease are also encouraged by this pathological occurrence. Reducing the advancement of …