Medicine and Health Sciences Commons^™

Factors Influence Homeless People’S Psychological Well-Being And Suicidal Ideation, Pi-Ming Yeh

Epsilon Sigma at-Large Research Conference

Introduction/Significance: About 582,462 individuals are experiencing homelessness in America. Homelessness is devastating, regardless of age. But for children, it can have serious physical, emotional, and psychological implications.

Purpose: The purpose of this study was to examine the influences of spiritual well-being, coping strategies, family interaction, and personality on psychological well-being, and suicidal ideation among people with homelessness.

Methods: Sixty people with homelessness were recruited in the Eastern Tennessee Downtown Day Center, USA. IRB was approved. This was a cross-sectional descriptive research design. Questionnaires were used to do data collection. SPSS 28.0 was used to do the data analysis. Descriptive …

Occupational Therapy Guided Interactive Workbook For College Students With Autism Spectrum Disorder For Transition Into The Workplace, Makayla Kirkley

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

The number of students with autism spectrum disorder entering college has been steadily increasing. When these graduates enter the workforce, the support and accommodations available throughout their education may not necessarily be readily available in their new workplace. This quality improvement project aimed to increase the resources of a college program whose purpose is to support autistic and neurodivergent students throughout their college career. The project aims were to create an interactive job readiness and independent living workbook to assist and provide resources for students during their transition into the workforce. The senior cohort completed seventeen fillable workbook pages with …

Dosage-Dependent, Carboplatin And Ng52 Show Synergistic Effect On Inhibiting Cell Proliferation In Breast Cancer Cell Line, Ben Couture, Ryan Zhuge

Biology Presentations

BT-549 (Breast Cancer), a highly invasive epithelial breast cancer cell line, was used to investigate the effects of two drugs: NG52, a selective kinase inhibitor and Carboplatin, a platinum-based DNA-alkylating agent. Using cell counting assays and calculating IC50 values, we examined their combined impact on cell proliferation. Results revealed both an antagonistic and synergistic effect dependent on concentration. Where the individual agents inhibited cell proliferation less effectively than expected. These findings show the complexity of drug interactions and provide insights into optimizing therapeutic strategies for highly invasive cancer types.

From Data To Impact: Integrating Research, Data Analysis, And Data Visualizations To Shape The Future Of Stroke Rehabilitation, Abigail Mcnaughton

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

This capstone project highlights the essential role of research in advancing occupational therapy (OT) practice and underscores the importance of data analysis and visualization in enhancing the communication and dissemination of research findings. Grounded in the Myers and Lotz Framework for Evidence-Based Practice and the CO-OP approach to problem-solving, the experience was structured around three core pillars: (1) gaining hands-on experience as a research therapist, (2) conducting in-depth data analysis, and (3) creating effective data visualizations to support scientific communication.

As a research therapist, I contributed to two ongoing studies: the Cognitive Priming (Cog-P) study and the Patient Quality Rating …

Acoustic Filter For Biopharmacy, Nicholas Rivet

Three Minute Thesis (3MT)

The design and development of a novel flow induced acoustically tuned “filterless” filter is proposed. The proposed research is on developing two or more prototypes that function as a cell retention device for perfusion cell cultures used in continuous manufacturing of monoclonal antibodies and recombinant proteins. This research will provide a non-invasive, cost-effective, flexible, and robust cell retention device for sustainable manufacturing of biologics.

Analyzing The Effectiveness Of Providing Religious And Spiritual-Based Care For Patients Currently Receiving Palliative Care Services, Rachel Ann Bruce, Cynthia Dien, Kinnice Jordan Turner, Rebecca Kay Tisdale

Student Scholar Showcase

This literature review explores the effectiveness of providing spiritual and religious-based care to patients currently receiving palliative care settings. In the context of this research, palliative care is defined as the six month period before a person’s death. By examining peer-reviewed journal articles from 2020 to 2024, this literature review will incorporate findings from multiple studies (both qualitative and quantitative) in order to effectively compare and contrast spiritual and religious beliefs and practices for patients receiving palliative care. After thorough examination, collected research has demonstrated that individuals who receive both timely and frequent religious and spiritual-base care while on palliative …

Advancing Scoliosis Care Through Pilates Training, Certification, And Outreach Initiatives, Jaryn Toms

OTD Capstone Projects

This doctoral capstone project was completed in collaboration with Spiral Spine Pilates (SSP), a Pilates studio specializing in scoliosis that serves clients from adolescents to older adults. SSP offers virtual and in-person private lessons, group classes, teacher training, and a scoliosis-focused retreat. These services are designed to educate individuals with scoliosis and movement practitioners on evidence-based, functional correction movements that support daily living. The primary objective of this project was to expand SSP’s educational reach through the development of new Pilates training, certifications, and outreach efforts. The primary outcome included the creation of an online certification program eligible for continuing …

Impact Of A Case-Based Learning Module: Integrating Authentic Treatment Videos, Electronic Documentation, And Hands-On Simulation, Emily Martin

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

INTRODUCTION: Developing student confidence and competence is essential for effective fieldwork preparation in occupational therapy (OT) education. Educators use diverse instructional methods to foster clinical readiness, including case-based learning (CBL), video cases, documentation practice, and simulation. CBL enhances critical thinking, clinical reasoning, self-awareness, and confidence. With advancements in technology, video CBL has become more accessible, using authentic patient videos to promote higher-level clinical reasoning, documentation, and communication skills, especially when paired with complementary learning activities. CBL video cases offer a logical opportunity to incorporate structured documentation training, an area in which health professions students often report feeling underprepared. Simulation …

Supporting Elementary Educators Through A Nervous System Regulation And Social-Emotional Learning Skills Workshop Intervention: An Musc Capstone Project, Lily Morgan

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

Teachers have a great influence on developing children’s emotional intelligence, regulatory capacity, and occupational engagement. These professionals also happen to report some of the highest rates of stress, mental health challenges (Agyapong, B. et al, 2022), and burnout (Xie, M., et al, 2022). Providing teachers with education and support on nervous system regulation, social-emotional learning skills, and related topics can improve their ability to manage job stress, enhance modeling and interactions with students, and improve their quality of life. This project aimed to enhance knowledge, provide access to resources, and serve to support elementary educators at an inner-city school in …

Web-Based Wellness, Katherine Shipers

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

Adults of all ages experience life stressors and transitions that impact their physical, emotional, and psychosocial wellness. Despite a recognized need for self-improvement, many adults face time constraints that limit their ability to engage in traditional wellness activities. Research suggests that micro-learning strategies—brief, targeted educational interventions—can effectively enhance knowledge and influence life practices.

This quality improvement capstone project explored the use of microlearning to support adult well-being by developing a web-based, modular learning system. The project implemented a series of short educational videos addressing various wellness topics, supplemented by corresponding worksheets and resource materials. Designed for asynchronous completion, these wellness …

The Neonatal Care Project: Empowering Parents Through Education And Support, Waverleigh Jenkins

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

The purpose of this capstone project was to develop and provide an informational and evidence-based resource for parents to utilize after discharge from the Shawn Jenkins Children’s Hospital (SJCH) Neonatal Intensive Care Unit (NICU). An in-depth needs assessment showed a need for increased parental support and better resources to improve parent mental health outcomes due to feelings of unpreparedness following a NICU stay. To support this goal, and in collaboration with the occupational therapy team at SJCH, two informational websites were created, one in English and the other in Spanish. The website is entitled “The Neonatal Care Project” and contains …

Developing A Scheduling Method For Animal-Assisted Therapy In Acute Rehabilitation, Abbegayle Sutterfield

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

Animal-Assisted Therapy (AAT) provides meaningful benefits in rehabilitation, including reduced anxiety and improved motivation and physical outcomes (Burres et al, 2016, Denzer-Weiler & Hreha, 2018). However, barriers such as inconsistent scheduling and limited clinician experience hinder implementation in fast-paced healthcare settings. This project took place at a large inpatient acute care hospital where therapy staff sought to integrate AAT more effectively into rehabilitation sessions.

The purpose of this quality improvement project was to develop a sustainable scheduling method to facilitate coordination between therapy staff and volunteer animal-handler teams. Goals included improving interdisciplinary communication, enhancing patient engagement through AAT, and creating …

What About Participation? Using Key Form Mapping To Emphasize Community Participation In Stroke Survivors, Sarah E. Humphrey

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

The purpose of this MUSC Occupational Therapy (OT) Doctoral Capstone project was to determine if stroke survivors demonstrate participation gains resulting from Rasch-derived, patient-spectice practice, i.e., “keyform mapping,” program by evaluation participation at 3 levels. Approximately 50% of stroke survivors have participation restrictions that may impact their engagement with fulfilling, meaningful activities. This is a secondary analysis of data collected from a stroke rehabilitation RCT parent study which tested the effect of a tailored. task-practice program using Rasch-derived keyform map of the individual’s FMA-UE item responses. Participation levels were evaluate by the Activity Card Sort Low-Demand Leisure and Social Acitivites …

Does Awareness Of Behavioral Challenges Impact The Preparedness Of Recent Slp Graduate Students For Their Professional Practice?, Madison K. Jones, Catherine L. Cotton Dr.

Undergraduate Research Conference

This research aims to explore how awareness of behavioral challenges, such as aggression, defiance, and hyperactivity, affects the preparedness of recent Speech-Language Pathology (SLP) graduates. With over 84% of children receiving SLP services also facing emotional or behavioral difficulties, it is crucial to examine whether new SLPs feel prepared to manage these challenges. The study seeks to assess whether increased awareness of behavioral issues correlates with greater confidence and readiness in addressing them during the first year of clinical practice. The study will involve administering a survey to first-year Speech-Language Pathologists. The survey will focus on their preparedness and their …

Natal And Neonatal Teeth In Mississippi Newborn, Keona Sanders, Anna Mcdowell, Dr. Sarah Mccrary

Undergraduate Research Conference

Title: Natal And Neonatal Teeth In Mississippi Newborns

Submission Type: Semester Long Research/ Oral Presentation

Abstract: In recent years, we have seen a growth in Mississippi infants being born with or growing teeth at an earlier stage. This may be caused by several things, like gestational age, maternal age, or possibly the mother’s diet. We are now looking for common similarities between these infants to see what the possible cause may be. Although this may not seem detrimental, this is still very harmful for infants, causing diseases like Riga Fede Disease. This is a disease that is caused by mandibular …

Management Of Sensory Processing Differences To Support Children’S Participation In Church, Sarah Allen

OTD Capstone Projects

This doctoral capstone project was completed in partnership with the First Presbyterian Church of Nashville (FPCN), with the shared objective of fostering a more inclusive and sensory-friendly environment within its Children’s Ministry. In alignment with FPCN’s mission to nurture young disciples through holistic, age-appropriate faith formation, this project addressed the growing need to accommodate children’s diverse sensory needs. Key outcomes included improved staff confidence as measured through pre- and post-training surveys, the creation of a resource binder on sensory processing, autism spectrum disorder (ASD), and attention-deficit/hyperactivity disorder (ADHD), and concrete changes to curriculum structure and classroom environments to better support …

Activity Levels Among Older Adults In A Life Plan Community, Emily D. Winters

OHSU-PSU School of Public Health Annual Conference

This study aimed to analyze resident's knowledge of the health and wellness programs available to them in their facility. It explored activity levels, preferred activity methods, and health and wellness program utilization among older adults residing in a life-plan community. A total of 166 survey respondents, aged 65 and older, were included in the analysis. Data were collected using a self-administered questionnaire designed to assess physical activity patterns, preferences for activity types, and engagement with the facility’s health and wellness offerings. Open-ended questions were assessed qualitatively through thematic analysis to find common themes within data. Results indicated that the most …

Association Between Arsenic And Other Heavy Metal Exposures Through Drinking Water And Food With Lung Function And Respiratory Symptoms: A Cross-Sectional Study, Sofia I. Chapela Lara, Seth O'Neal Md, Mph For The Cysticercosis Working Group In Peru

OHSU-PSU School of Public Health Annual Conference

Impaired lung function is a major health concern, particularly in children, as it increases the risk of chronic respiratory diseases and long-term morbidity. Environmental exposure to heavy metals (HMs) such as arsenic, lead, cadmium, and manganese has been associated with reduced lung function and respiratory symptoms. However, findings vary by exposure context and population, with limited research in pediatric populations and few studies evaluating the combined effects of multiple HMs. These exposures disproportionally affect marginalized rural communities, especially in low and middle-income countries with mining activities. This cross-sectional study investigated the association between exposure to As and other HMs through …

The Relevance Of Gut Microbiota For The Activity Of Herbal Drugs, Rudolf Bauer

Oxford ICSB

Despite intensive research, the active principles and mechanisms of action of many herbal drugs are still not clear. Moreover, the bioavailability of many polar plant constituents is rather limited, why they are not likely to act systemically. Therefore, alternative approaches to explain their activity have to be considered. Gut microbiota and the human body form a symbiosis which is essential for our health and well-being. Dysbiosis can lead to various diseases, like inflammation, obesity, asthma, diabetes, and even cancer. Therefore, gut microbiota are a relevant target for herbal drugs, and may help to understand their effects. For example, Faecalibacterium prausnitzii …

Insights From Ethnobotanical Research In North America, Latin America, And West Africa Into The Phytochemical Quality, Pharmacokinetics, Pharmacodynamics, And Toxicology Of Botanicals, Robin Marles

Oxford ICSB

Insights perhaps worth sharing have been gained over a career spanning 50 years of ethnobotanical and pharmacognostic research on botanicals of Canada, Mexico, Ecuador, and Togo, and the development of standards on the quality, safety, and evidence-based uses of botanicals in health products and foods. Perspectives provided by traditional healers in these countries have informed approaches to a better understanding of, and possible goals for future research on traditionally used plants. This includes their phytochemical quality; absorption, distribution, metabolism, and excretion; possible mechanisms of action; and potential safety concerns. These insights will be illustrated by specific examples from research conducted …

Enhancing Understanding Of Infant Cues And The Role Of Rehabilitative Therapies In The Neonatal Intensive Care Unit, Lexie Jones

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

Research emphasizes the importance of early rehabilitative therapy involvement in the NICU to improve outcomes for preterm infants. The American Academy of Pediatrics (AAP) recommends the presence of occupational therapy (OT) and speech-language therapy (SLP) services in Level III NICUs to enhance neurodevelopment, promote feeding success, and support interdisciplinary collaboration (AAP, 2020). Cue-based feeding approaches have been linked to improved weight gain, reduced hospital stays, and decreased physiological stress in preterm infants compared to volume-driven approaches (Pados et al., 2020). However, limited staff understanding of infant behavioral cues and the distinct roles of OT and SLP can lead to missed …

Maternal Physical And Mental Health In The State Of South Carolina: Creating High-Quality Educational Materials, Elizabeth Chard

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

This capstone project, in collaboration with the Empowering Moms team at the Medical University of South Carolina, aimed to establish the foundation for a statewide occupational therapy initiative focused on maternal mental and physical health education as a preventative approach to addressing rising maternal mortality rates. The project involved assessing the needs of mothers, developing evidence-based educational materials, and compiling a comprehensive resource list to enhance access to information for mothers and community health partners (CHPs) across South Carolina. To support this initiative, a website and REDCap surveys were created to facilitate information dissemination and track outcomes. Embedded within the …

87 - Maternal Dental Status And Caries Among Siblings, Monica Walker, Charity Hammond, Angela Wilson, Denise Mckinney, Katie Protogyrou

Undergraduate Research Symposium

Research has suggested that birth order or environmental factors affect siblings' oral health status during childhood. However, more recent research suggests that the strongest predictor of children's oral health status is the mother's oral health status. This project investigated the association between the oral health status of the mother during pregnancy and bacteria (biofilms) identified in cavitated lesions (dental caries) of their children’s exfoliated primary teeth. Five consenting maternal participants anonymously donated their children's primary teeth and completed a questionnaire about their oral health status during each pregnancy. After visually identifying the exfoliated teeth with dental caries, the biofilms were …

Unlocking Nature’S Pharmacy: Using Hidden Secrets From Post Famine Ireland To Direct Modern Scientific Exploration Of Irish Bogland Species., Helen Sheridan

Oxford ICSB

Boglands are iconic landscapes and important carbon sinks, extending across the northern hemisphere, covering approximately 20% of Ireland's land area. These ancient water-logged ecosystems are reservoirs of a unique biodiversity adapted to survive in nutrient-poor yet strikingly beautiful environments. Irish mythology is deeply connected to boglands, featuring stories about healing plants, fairies, and ancient curses. Irish communities historically used bogland plants for their medicinal properties. Many uses are recorded in the Schools' Manuscript Collection (SMC) (1937-1939), a treasure-trove of Irish folklore, customs, and ethnographic data, collected as part of the Irish Folklore Commission's effort to preserve Ireland’s oral traditions (Dúchas.ie). …

The Contribution Of The European Pharmacopoeia To The Quality Control Of Herbal Medicinal Products, Salvador Canigueral

Oxford ICSB

The European Pharmacopoeia (Ph. Eur.) is an international regulatory document setting the standards for the quality control of medicinal products. It is elaborated by the European Directorate for the Quality of Medicines & HealthCare (EDQM), a body of the Council of Europe, headquartered in Strasbourg, France. It is mandatory in 39 European countries and the European Union. The Ph. Eur. establishes quality specifications for active ingredients, excipients, dosage forms, and finished products. In relation to herbal medicinal products, the upcoming 12th Edition (effective January 2026) includes: 25 general methods in pharmacognosy, 6 general monographs, 2 information chapters, and 392 individual …

Bioseq: A Molecular Intelligence Platform Based On Organism-On-Chip Technology For Bridging Data Gaps Between C. Elegans And Humans, Hunter Edwards, Adnan Qureshi, Mizanur Rahman, Tyler Chiriboga, Amar Chittiboyina, Ikhlas Khan, Siva Vanapalli

Oxford ICSB

The FDA Modernization Act 2.0, emphasizes the urgent need for New Approach Methodologies (NAMs) to replace conventional animal testing in safety and efficacy assessments. NemaLife’s organism-on-chip platform, utilizing C. elegans, microfluidics and visual AI, provides a high throughput platform for in vivo screening. To enhance human relevance and reduce the inter-species gap between C. elegans and human, we developed BioSeq, a novel discovery workflow, based on high-throughput transcriptomics. Leveraging the 60-80% homology between C. elegans and human genomes, BioSeq translates worm gene expression data to human orthologs. This enables: (i) identification of differentially expressed human-relevant genes triggered by bioactive ingredients …

Current Regulatory And Enforcement Landscape Under Mocra, Diane Mcenroe

Oxford ICSB

The Modernization of Cosmetics Regulation Act of 2022 (MoCRA) became effective December 29th, 2023 and is the most significant expansion of FDA’s authority to regulate cosmetics since the FD&C Act was enacted in 1938. MoCRA expands the FDA's authority over cosmetics and creates new compliance obligations for manufacturers. Diane McEnroe, an FDA regulatory lawyer at Sidley Austin, LLP, will provide an overview of the law and its implication for cosmetic manufacturers and marketers. The presentation will also provide an update on the current regulatory and enforcement landscape to date, including considerations about follow on litigation when there has been publicity …

Cosmetic Adverse Events And The Product Safety Landscape, Rick Kingston

Oxford ICSB

The Modernization of Cosmetics Regulation Act of 2022 (MoCRA) became effective December 29th, 2023 and is the most significant expansion of FDA’s authority to regulate cosmetics since the FD&C Act was enacted in 1938. MoCRA expands the FDA's rulemaking and enforcement authority over cosmetics and creates new compliance obligations for manufacturers. There are six key areas of the legislation including Facility Registration, Product & Ingredient Listing, Safety Substantiation, Cosmetics Labeling, and Adverse Event Reporting and Record Keeping. Each of these areas has significant implications for manufacturers and cosmetic ingredients. Given the ubiquitous presence of botanical and other naturally occurring substances …

Herbal Medicine For The Management Of Asthma In Taiwan: Insights From Big Data, Laboratory Studies, And Clinical Research, Hung-Rong Yen, Chuan-Teng Liu, Ying-Chyi Song

Oxford ICSB

Introduction: Asthma affects individuals across all age groups and poses a significant public health challenge in Taiwan, with high morbidity rates and substantial healthcare burdens. Traditional medicine theory emphasizes restoring the yin-yang balance, achieved through methods such as herbal medicine. Real-world data from Taiwan highlight the growing reliance on complementary therapies due to recurrent exacerbations and the potential side effects of conventional asthma medications. Materials and Methods: First, we analyzed the National Health Insurance Research Database, encompassing a population of 23 million in Taiwan, to identify the most commonly prescribed Chinese herbal medicines. Subsequently, we conducted in vitro experiments and …

Intoxicating Cannabinoids And Impurities In Hemp-Derived Products In Us Markets, Mahmoud Elsohly

Oxford ICSB

This talk will examine the nature and source of a number of intoxicating cannabinoids and impurities, widely available in the US and marketed as “hemp-derived” and thus promoted as legal and safe products. The presentation will elaborate on the 2018 Farm Bill, the definition of Hemp and the consequences of the interpretation of the definition on the composition of products on the market. Of particular emphasis will be the prevalence of Delta-8 THC in these products and the incorporation of their intoxicating cannabinoids.