Medicine and Health Sciences Commons^™

A Mathematical Model For Antibiotic Resistance In A Hospital Setting With A Varying Population, Edward H. Snyder

Electronic Theses and Dissertations

Antibiotic-resistant bacteria(ARB) is causing increased health risk and cost to society. Mathematical models have been developed to study the transmission of resistant bacteria and the efficacy of preventive measures to slow its spread within a hospital setting. The majority of these models have assumed a constant total hospital population with the admission and discharge rates being equal throughout the duration. But a typical hospital population varies from day to day and season to season. In this thesis, we apply variable admission and discharge daily rates to existing deterministic and stochastic models which examine the transmission of single and dual resistant …

Integrative Biomarker Identification And Classification Using High Throughput Assays, Pan Tong

Dissertations and Theses (Open Access)

It is well accepted that tumorigenesis is a multi-step procedure involving aberrant functioning of genes regulating cell proliferation, differentiation, apoptosis, genome stability, angiogenesis and motility. To obtain a full understanding of tumorigenesis, it is necessary to collect information on all aspects of cell activity. Recent advances in high throughput technologies allow biologists to generate massive amounts of data, more than might have been imagined decades ago. These advances have made it possible to launch comprehensive projects such as (TCGA) and (ICGC) which systematically characterize the molecular fingerprints of cancer cells using gene expression, methylation, copy number, microRNA and SNP microarrays …

Patients With Disabilities As Teachers (P-Dat) Training In Medical Education, Rebecca Royce-Hickey Do, Sweety Jain Md, Susan E. Hansen Ma, Nyann Biery Ms

Department of Family Medicine

No abstract provided.

Concurrent Neurological And Behavioral Assessment Of Number Line Estimation Performance In Children And Adults, Joseph Michael Baker

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Understanding the brain’s response to common math-learning activities may help improve math education. For example, by imaging the brains of typically developing children and adults throughout a number line estimation task, it is possible to establish a baseline of what “typical” brains do in such situations. Thus, comparisons may be made to determine the degree to which brain functioning differs between typical and atypical math learners. Moreover, by identifying methods that may increase the brain’s response to real-world math activities, it may be possible to improve the math learning process for typical and atypical learners alike.

Brain imaging devices such …

Alpcs(2a)-Mediated Photochemical Internalization Of Bleomycin And Concurrent Hyperthermia Of Multicellular Tumor Spheroids, Aaron Andersen

UNLV Theses, Dissertations, Professional Papers, and Capstones

Treatments for glioblastoma multiforme and invasive ductal carcinoma involve surgical resection and adjuvant or concurrent targeted therapies. The goal of the secondary treatment is to reduce the cancer cells in the resection margin and other areas of suspected involvement. Photochemical internalization is a targeted therapy using light to activate photosensitizers embedded in cellular structures to improve the delivery of macromolecules within the cell.

In a previous study, optimized treatment parameters including radiant exposure, and irradiance, concentration of AlPcS(2a), temperature, and the concentration of bleomycin were determined for human ACBT glioma multicell spheroids. The current study investigates the effectiveness of the …

The Santa Clara, 2013-04-25, Santa Clara University

The Santa Clara

No abstract provided.

2013 - The Eighteenth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Eighteenth Annual Symposium of Student Scholars, held on April 25, 2013. Includes abstracts from the presentations and posters.

Bryant University Research And Engagement Day Program

Bryant REDay (Research and Engagement Day)

No abstract provided.

The Santa Clara, 2013-04-18, Santa Clara University

The Santa Clara

No abstract provided.

12th Annual Undergraduate Student Symposium, Farquhar Honors College

Undergraduate Student Symposium

The Undergraduate Student Symposium, sponsored by the Farquhar College of Arts and Sciences, presents student projects through presentations, papers, and poster displays. The event serves as a “showcase” demonstrating the outstanding scholarship of undergraduate students at NSU. The Symposium is open to undergraduate students from all disciplines. Projects cover areas of student scholarship ranging from the experimental and the applied to the computational, theoretical, artistic, and literary. They are taken from class assignments as well as from independent projects. The projects do not have to be complete; presentations can represent any stage in the concept’s evolution, from proposal and literature …

Wright State University Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts Friday, April 12, 2013, Wright State University Office Of Undergraduate Research And Stemm Activities

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's second annual Celebration of Research, Scholarship and Creative Activities on April 12, 2013.

The Santa Clara, 2013-04-11, Santa Clara University

The Santa Clara

No abstract provided.

The Santa Clara, 2013-04-04, Santa Clara University

The Santa Clara

No abstract provided.

Instrumental Music Ensemble At Tennessee State University: The Early Years (1912-1946), Reginald A. Mcdonald

The Journal of Tennessee State University

No abstract provided.

The Resilience Of One Tennessee State University Professor In Providing A Path To Excellence For Youths, Sean Daniels

The Journal of Tennessee State University

No abstract provided.

Diffusion Of Mobile Payment Systems Among Microentrepreneurs In Kenya And Tanzania, Dionne Nickerson

Annual Celebration of Student Scholarship and Creativity

The rapid rise of Kenya's mobile payment system, M-PESA , has grasped the attention of policy makers and private enterprise alike. In just six years M-PESA has transformed how money flows throughout Kenya, and similar systems are gaining traction elsewhere in Africa. This project examines the impact of mobile payment system adoption on the economic advancement of Kenyan and Tanzanian microentrepreneurs. This work will further the understanding of mobile payment systems’ contribution to the economic growth of microenterprises, which may have implications for poverty reduction in these two nations.

Self-Directed Learning Readiness And Self-Determination For Selected Rehabilitation Professional Students: The Impact Of Clinical Education, Shelley S. Payne, Peter Rundquist, William V. Harper, Julie Gahimer

Mathematics Faculty Scholarship

In a time of rapidly changing medical information, practitioners must have learning skills that enable them to be effective life-long learners. A part of an examination of a final clinical internship for rehabilitation professionals was a pre-post measure of learner self-direction and self-determination. Two instruments, the Self-Directed Learning Readiness Scale (SDLRS) and the Academic Motivation Scale (AMS- reported as Self-Determination Index (SDI) were used with a sample of Doctorate of Physical Therapy (DPT) and Master of Occupational Therapy (MOT) students. Pre-testing occurred just prior to and post-testing just after the subjects’ final clinical assignments. Both groups increased mean scores from …

[Sabbatical Report], Emmanuel Iyiegbuniwe

Sabbatical Reports

The main purpose of this sabbatical leave was to provide me the opportunity to conduct relevant research and subsequently write two book chapters on environmental health and policy issues in two countries: Belize (a developing country) and Canada (a developed country). Specifically, the two book chapters were titled "Analysis of Environmental Health Policy in Belize" and "Analysis of Environmental Health and Policy Issues in Canada." As called for in my proposal, I was able to travel to Belize with a group of CHHS faculty and students during the 2013 winter term. During the leave period, I success fully conducted research …

Los Agroquímicos Usados En Las Plantaciones Bananeras Y Sus Efectos En El Agua, La Gente, Y El Ambiente En La Comunidad De Changuinola, Bocas Del Toro, Panamá., Daniela Rossi

Independent Study Project (ISP) Collection

Esta investigación analiza los efectos de los químicos que se usan en forma de fertilizantes, nematicidas, insecticidas, y pesticidas en las plantaciones bananeras en Changuinola, Panamá. Esta investigación analiza la relación entre estos químicos y la salud de la gente de la comunidad que vive adentro de las bananeras, la salud de los trabajadores de los bananales, y los efectos en el ambiente, específicamente el agua. Este estudio se realizo por medios de entrevistas informales y por analices de muestras de agua en fincas bananeras en el laboratorio de IDAAN. Los posos de agua analizados fueron de Fincas 03, 04, …

Inflammatory Findings On Species Extrapolations: Humans Are Definitely No 70-Kg Mice, Marcel Leist, Thomas Hartung

Validation of Alternative Methods Collection

Modern toxicology has embraced in vitro methods, and major hopes are based on the Omics technologies and systems biology approaches they bring along (Hartung and McBride in ALTEX 28(2):83–93, 2011; Hartung et al. in ALTEX 29(2):119–28, 2012). A culture of stringent validation has been developed for such approaches (Leist et al. in ALTEX 27(4):309–317, 2010; ALTEX 29(4):373–88, 2012a; Toxicol Res 1:8–22, 2012b), while the quality and usefulness of animal experiments have been little scrutinized. A new study (Seok et al. 2013) now shows the low predictivity of animal responses in the field of inflammation. These findings corroborate earlier findings from …

Fertile Lands And Bodies: Connecting The Green Revolution, Pesticides, And Women’S Reproductive Health, Sarah M.K. Cycon

Pitzer Senior Theses

Environmentalists, social scientists, and economists have long critiqued the enduring impacts of the Green Revolution’s diffusion of agricultural technologies throughout the Global South. However, largely missing from the myriad analyses is the relationship between those technologies, namely pesticides, and health outcomes. This thesis explores the social and biological mechanisms through which excessive pesticide use culminated into adverse reproductive health outcomes for rural women in the Global South. Drawing together the history of the Green Revolution’s use of DDT, its social and economic impacts, and the biology of pesticide contamination in women’s bodies exposes how the Green Revolution situated women in …

Study Of The Insulin Mimetic Sodium Orthovanadate In Glucosamine Induced Insulin Resistnace In Primary Rat Hepatocytes, Kalan Mcpherson

Masters Theses

Insulin resistance and type II diabetes is a disease state characterized by a lack of sensitivity of insulin to provoke a proper response in insulin sensitive tissues. Currently, we utilize glucosamine to increase flux through the Hexosamine Biosynthetic Pathway (HBP) to induce an insulin resistance like state in primary rat hepatocytes. We tested the effectiveness of the insulin mimetic sodium orthovanadate to determine if it could elicit an insulin-like response under these conditions. Mixed results were obtained on the effectiveness of vanadate as an insulin mimetic in this insulin resistant model.

Daily Walking And Life Expectancy Of Elderly People In The Iowa 65+ Rural Health Study, Hani M. Samawi

Biostatistics: Faculty Publications

The purpose of this paper is to investigate the hypothesis that outdoor daily walking, as an exercise, has an effect on the rate of mortality among those elderly people in the Iowa 65+ Rural Health Study (RHS). RHS is a prospective longitudinal cohort study of 8 years follow-up from 1981 to 1989. It consists of a random sample of 3,673 individuals (1,420 men and 2,253 women) aged 65 or older living in Washington and Iowa counties of the State of Iowa. Our analysis was conducted only on those non-institutional individuals who could without any help walk across a small room; …

Volume 05, Ian Karamarkovich, Jessica Cox, Kyle Fowlkes, Allison Pawlowski, Kaitlin Major, Carrie Dunham, Kelsey Scheitlin, Kathryn Grayson, Ashley Johnson, Jennifer Nehrt, Kelsey Stolzenbach, Kristin Mcquarrie, Sara Nelson, Melisa Michelle, Jessica Sudlow, Perry Bason, Danielle Dmuchawski, Mariah Asbell, Matthew Sakach, Timothy Smith Jr., Annaliese Troxell, T. Dane Summerell, Sarah Ganrude, Malina Rutherford, Hannah Hopper, John Berry Jr., James Early, Colleen Festa, Chelsea D. Taylor, Michelle Maddox, Kaitlyn Smith, Sarah Schu, Cabell Edmunds, Katherine Grayson, Kayla Tornai

Incite: The Journal of Undergraduate Scholarship

Introduction from Dean Dr. Charles Ross

The Tallis House as an Extension of Emily Tallis in McEwan's Atonement by Ian Karamarkovich

Graphic Design by Jessica Cox

Graphic Design by Kyle Fowlkes

Graphic Design by Allison Pawlowski

Incorporating Original Research in The Classroom: A Case Study Analyzing the Influence of the Chesapeake Bay on Local Temperatures by Kaitlin Major, Carrie Dunham and Dr. Kelsey Scheitlin

Graphic Design by Kathryn Grayson

Graphic Design by Ashley Johnson

Facing the Music: Environmental Impact Assessment of Building A Concert Hall on North Campus by Jennifer Nehrt, Kelsey Stolzenbach And Dr. Kelsey Scheitlin

Art by Kristin …

43rd Annual Wku Student Research Conference, Student Research Council, Western Kentucky University

Student Research Conference Select Presentations

No abstract provided.

Causes Of Death In Surgically Treated Patients With Type A Aortic Dissection - A Ten Year Review, James K. Wu Md, Eilizabeth Depaolo Bs, Theodore G. Phillips Md, Timothy S. Misselbeck

Department of Surgery

No abstract provided.

The Net Reclassification Index (Nri): A Misleading Measure Of Prediction Improvement With Miscalibrated Or Overfit Models, Margaret Pepe, Jin Fang, Ziding Feng, Thomas Gerds, Jorgen Hilden

UW Biostatistics Working Paper Series

The Net Reclassification Index (NRI) is a very popular measure for evaluating the improvement in prediction performance gained by adding a marker to a set of baseline predictors. However, the statistical properties of this novel measure have not been explored in depth. We demonstrate the alarming result that the NRI statistic calculated on a large test dataset using risk models derived from a training set is likely to be positive even when the new marker has no predictive information. A related theoretical example is provided in which a miscalibrated risk model that includes an uninformative marker is proven to erroneously …

Online Survey System For Image-Based Clinical Guideline Studies Using The Delphi Method, Todd Martin Harper

Theses and Dissertations

The increasing use of health information technology (HIT) is due to a rising interest in improving the quality of health care. HIT has the potential to reduce cost and transform services. Proper clinical support systems will contribute to the meaningful use of HIT systems by providing a wide array of data to clinicians for the diagnosis and treatments. Clinical guidelines, created by a consensus of experts, can be put in place to assist physicians in making clinical decisions. Delphi methods are commonly used to create consensus from surveys completed by a team of experts. Image-based studies could create guidelines that …

A Biodistribution And Toxicity Study Of Cobalt Dichloride–Nacetyl Cysteine (C4) As An Implantable Mri Marker For Prostate Cancer Treatment, Steven J. Frank, Mary J. Johansen, Karen S. Martirosyan, Mihai Gagea, Carolyn S. Van Pelt

Physics & Astronomy Faculty Publications

Purpose—C4, a cobalt dichloride–N-acetyl cysteine complex, is being developed as a positivesignal magnetic resonance imaging (MRI) marker to localize implanted radioactive seeds in prostate brachytherapy. We evaluated the toxicity and biodistribution of C4 in rats with the goal of simulating systemic effects of potential leakage from C4 MRI markers within the prostate.

Methods—9 μl doses (equivalent to leakage from 120 markers in a human) of control (0.9% sodium chloride), 1% (proposed for clinical use) and 10% C4 solution were injected into the prostates of male Sprague-Dawley rats via laparotomy. Organ toxicity and cobalt disposition in plasma, tissues, feces …

Just Beautiful Portrays Of The Mind? The Relevance Of Aesthetic Strategies On Knowledge Creation In Neuroscience, Valerie Kummer

The Transdisciplinary STEAM+ Journal

We live in the age of big data. All types of data are being generated at an increasing rate but theories about the strategies and methods to visualize them is lagging. One of the main challenges we face today in research is to keep up with the massive amounts of data we produce (Allen, Elena A. et.al, 2012). Especially in the field of neuroscience and its use of imaging technologies, the vast array of data has risen to such a high number that it is impossible to grasp the inherent information without additional software tools and intelligent interfaces. Only through …