Medicine and Health Sciences Commons^™

Experimental Study Of Bent Glass Curtain Walls., Sarah Said Abd El Kariem, Moustafa El Shami, Mahmoud El Nagar

Journal of Engineering Research

A Bent Laminated Glass is commonly used in the residential and commercial structures, its methodology is not present in the curves and tables at the ASTM E1300. Therefore, it has become a need for architects to use basis for this type of glass. To the best of authors ‘knowledge, no one study the bent laminated glass in details. A variety of safety glass that has lately gained popularity in the construction sector is modern laminated glass. Given that it offers a safe failover capability, it is perfect for the automotive industry. Double-lite glass is produced using two or more …

Market Analysis And Bidding Strategy Of Hybrid Renewable Energy Systems Considering Emissions, Fatma Elzahraa, Mohamed Elnemr, Samir Dawoud

Journal of Engineering Research

The competition in the electricity markets makes it difficult to choose a suitable strategy for maximizing profit while reducing harmful emissions. To have an adequate energy price for consumers while minimizing the harmful emissions to the atmosphere and maximizing profits of all participants in the electricity market needs an aggressive bidding strategy. Developing these bidding strategies with the integration of renewable energy (RE) in the electricity market became important. This research studies various bidding strategies for maximizing profits in the deregulated energy market since participants are keen on developing bidding strategies considering emissions. These bidding strategies will consider the integration …

Effects Of Fuel Equivalence Ratio And Swirl Vane Angles On Premixed Burner Turbulent Flame Combustion Characteristics, Medhat Elkelawy Prof. Dr. Eng., E. A. El Shenawy Prof. Dr., Hagar Alm-Eldin Bastawissi Prof. Dr. Eng., Ibrahim Ali Mousa Eng., Mohamed M. Abdel-Raouf Ibrahim Dr. Eng.

Journal of Engineering Research

A turbulent flow field has a major effect on the premixed flame structure and temperature distribution that specifically determines the effectiveness of the burned fuel and the amounts of produced emissions. However, the premixed flame tangential and axial velocity distribution through the flame length help to predict the combustion and emissions attributes of the burned fuel. In this regard, an experimental and analytical investigation on premixed turbulent burners at different equivalence fuel-air ratios with different swirl vane angles has been achieved in the present work to assess the combustion performance and emissions characteristics. A theoretical methodology was carried out to …

Enhancing The Performance Of Conventional Solar Still Using The Nano-Doped Paint (Ndp) Coating, Hagar Alm-Eldin Bastawissi Prof.Dr, Nermin Elgendy Engineer, Ayman R. El-Tohamy

Journal of Engineering Research

Nations are throughout the entire globe continuously confronting the problem of potable water shortage. Recently, it has been thought that using solar energy to desalinate brackish water offers a practical answer to the world's water crises. The output of these stills, is meager, and academics haven't done much to boost it in any way. Solar distillers have been proposed as an efficient method to produce potable water. In recent years, saltwater has produced drinking water by various ways. The efficiency of a solar distiller is significantly influenced by various factors, most important factor of them is the absorber surface. In …

Engine Performance And Emissions Improvement Study On Direct Injection Of Diesel/Ammonia Dual Fuel By Adding Cng As Partially Premixed Charge, Medhat Elkelawy Prof. Dr, Eng., Hagar Alm-Eldin Bastawissi Prof. Dr., Mohammed Osama Elsamadony Dr. Eng., Abdallah Salem Abdalhadi Eng.

Journal of Engineering Research

Researchers have recently moved on in their studies to find a solution to prevent or reduce this problem. There have been directions taken by researchers to solve the problem, including, replacing fossil fuels with environmentally friendly types or by combining two or more types of fuel. This is by modifying fuel injection systems as appears in the PCCI, RCCI, or HCCI systems, or working to integrate the two trends by using new injection systems and burning alternative fuels with fossil fuels. Therefore, the trend has good results on the specific consumption of fuel, raising thermal efficiency, and working to reduce …

Experimental Study On The Impact Of Secondary Air Injection And Different Swirl Van Angles On Premixed Turbulent Flame Propagation And Emission Behaviors, Medhat Elkelawy Prof. Dr. Eng., E. A. El Shenawy Prof. Dr., Hagar Alm-Eldin Bastawissi Prof. Dr. Eng., Ibrahim Ali Mousa Eng., Mohamed M. Abdel-Raouf Ibrahim Dr. Eng.

Journal of Engineering Research

The objective of the present paper is to investigate experimentally the flame characteristics utilizing different secondary air inlet direction for different primary air swirl numbers and equivalence fuel-air ratios. In this study, an experimental test rig was carried out to investigate the flame temperature and emission behavior with flame length at the equivalence fuel-air ratios taken0.96, 0.80, 0.70, and 0.60, and swirl vane angles were varied as 20, 30, 45, and 60° to generate different swirl numbers of 0.26, 0.416, 0.71 and 1.23, respectively. In addition to the introduction of secondary air in test combustor, whereas the primary air and …

The Effect Of An Existing Tunnel And A Newly Excavated Tunnel On Ground Loss Beneath Sand Slope-3d Numerical Study, Ashraf Nazir, Ahmed Nasr, Asmaa Saeed

Journal of Engineering Research

Abstract- Most researchers perform their numerical models for tunnels by modeling perfectly horizontal ground surfaces above the tunnels. The prediction of surface settlement of a sandy slope due to the interaction mechanism between the slope and the tunnels is one of the critical problems in urban areas. As a result, in this work, a numerical analysis using PLAXIS 3D TUNNEL has been performed to investigate the effect of tunnel excavation on the deformation of a shallow sandy slope, and empirically by the Herzog method. The study also assesses the influence of parameters on slope deformation that have not been …

Regulation Of Polysaccharide In Wu-Tou Decoction On Intestinal Microflora And Pharmacokinetics Of Small Molecular Compounds In Aia Rats, Di Yang, Xiaoxu Cheng, Meiling Fan, Dong Xie, Zhiqiang Liu, Fei Zheng, Yulin Dai, Zifeng Pi, Hao Yue

Faculty, Staff and Student Publications

Wu-tou decoction (WTD), a traditional Chinese medicine prescription, is used to treat rheumatoid arthritis (RA). It works by controlling intestinal flora and its metabolites, which in turn modulates the inflammatory response and intestinal barrier function. Small molecular compounds (SM) and polysaccharides (PS) were the primary constituents of WTD extract. In this work, a model of adjuvant-induced arthritis (AIA) in rats was established and treated with WTD, SM, and PS, respectively. 16S rRNA gene sequencing was used to examine the regulatory impact of the various groups on the disturbance of the gut flora induced by RA. Further, since PS cannot be …

Prediction Of Hydrogel Degradation Time Based On Central Composite Design, Ying Wang, Deji Liu, Ruiquan Liao, Guangming Zhang, Manlai Zhang, Xiaohui Li

Faculty, Staff and Student Publications

In this study, a self-degrading hydrogel was formed by free-radical-initiated copolymerization, which can be used for oil and gas well strip pressure operations. Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance (1H NMR), scanning electron microscopy (SEM), and thermogravimetry-mass spectrometry (TGA-MS) were used to study the reaction mechanism as well as the microstructure of the gels. Then, the effects of the four factors and their interactions on gel degradation time were determined by central composite design (CCD). Then, the effects of copolymer concentration, cross-linker, initiator, and reaction temperature and their interactions on gel degradation time were determined by central composite …

Fusionneoantigen: : A Resource Of Fusion Gene-Specific Neoantigens, Himansu Kumar, Ruihan Luo, Jianguo Wen, Chengyuan Yang, Xiaobo Zhou, Pora Kim

Faculty, Staff and Student Publications

Among the diverse sources of neoantigens (i.e. single-nucleotide variants (SNVs), insertions or deletions (Indels) and fusion genes), fusion gene-derived neoantigens are generally more immunogenic, have multiple targets per mutation and are more widely distributed across various cancer types. Therefore, fusion gene-derived neoantigens are a potential source of highly immunogenic neoantigens and hold great promise for cancer immunotherapy. However, the lack of fusion protein sequence resources and knowledge prevents this application. We introduce 'FusionNeoAntigen', a dedicated resource for fusion-specific neoantigens, accessible at https://compbio.uth.edu/FusionNeoAntigen. In this resource, we provide fusion gene breakpoint crossing neoantigens focused on ∼43K fusion proteins of ∼16K in-frame …

Drmref: Comprehensive Reference Map Of Drug Resistance Mechanisms In Human Cancer, Xiaona Liu, Jiahao Yi, Tina Li, Jianguo Wen, Kexin Huang, Jiajia Liu, Grant Wang, Pora Kim, Qianqian Song, Xiaobo Zhou

Faculty, Staff and Student Publications

Drug resistance poses a significant challenge in cancer treatment. Despite the initial effectiveness of therapies such as chemotherapy, targeted therapy and immunotherapy, many patients eventually develop resistance. To gain deep insights into the underlying mechanisms, single-cell profiling has been performed to interrogate drug resistance at cell level. Herein, we have built the DRMref database (https://ccsm.uth.edu/DRMref/) to provide comprehensive characterization of drug resistance using single-cell data from drug treatment settings. The current version of DRMref includes 42 single-cell datasets from 30 studies, covering 382 samples, 13 major cancer types, 26 cancer subtypes, 35 treatment regimens and 42 drugs. All datasets in …

Cov2var, A Function Annotation Database Of Sars-Cov-2 Genetic Variation, Yuzhou Feng, Jiahao Yi, Lin Yang, Yanfei Wang, Jianguo Wen, Weiling Zhao, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has resulted in the loss of millions of lives and severe global economic consequences. Every time SARS-CoV-2 replicates, the viruses acquire new mutations in their genomes. Mutations in SARS-CoV-2 genomes led to increased transmissibility, severe disease outcomes, evasion of the immune response, changes in clinical manifestations and reducing the efficacy of vaccines or treatments. To date, the multiple resources provide lists of detected mutations without key functional annotations. There is a lack of research examining the relationship between mutations and various factors such as disease severity, pathogenicity, patient age, patient gender, cross-species …

Ageannomo: A Knowledgebase Of Multi-Omics Annotation For Animal Aging, Kexin Huang, Xi Liu, Zhaocan Zhang, Tiangang Wang, Haixia Xu, Qingxuan Li, Yuhao Jia, Liyu Huang, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

Aging entails gradual functional decline influenced by interconnected factors. Multiple hallmarks proposed as common and conserved underlying denominators of aging on the molecular, cellular and systemic levels across multiple species. Thus, understanding the function of aging hallmarks and their relationships across species can facilitate the translation of anti-aging drug development from model organisms to humans. Here, we built AgeAnnoMO (https://relab.xidian.edu.cn/AgeAnnoMO/#/), a knowledgebase of multi-omics annotation for animal aging. AgeAnnoMO encompasses an extensive collection of 136 datasets from eight modalities, encompassing 8596 samples from 50 representative species, making it a comprehensive resource for aging and longevity research. AgeAnnoMO characterizes …

Stemdriver: A Knowledgebase Of Gene Functions For Hematopoietic Stem Cell Fate Determination, Yangyang Luo, Jingjing Guo, Jianguo Wen, Weiling Zhao, Kexin Huang, Yang Liu, Grant Wang, Ruihan Luo, Ting Niu, Yuzhou Feng, Haixia Xu, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

StemDriver is a comprehensive knowledgebase dedicated to the functional annotation of genes participating in the determination of hematopoietic stem cell fate, available at http://biomedbdc.wchscu.cn/StemDriver/. By utilizing single-cell RNA sequencing data, StemDriver has successfully assembled a comprehensive lineage map of hematopoiesis, capturing the entire continuum from the initial formation of hematopoietic stem cells to the fully developed mature cells. Extensive exploration and characterization were conducted on gene expression features corresponding to each lineage commitment. At the current version, StemDriver integrates data from 42 studies, encompassing a diverse range of 14 tissue types spanning from the embryonic phase to adulthood. In order …

Fusionpdb:: A Knowledgebase Of Human Fusion Proteins, Himansu Kumar, Lin-Ya Tang, Chengyuan Yang, Pora Kim

Faculty, Staff and Student Publications

Tumorigenic functions due to the formation of fusion genes have been targeted for cancer therapeutics (i.e. kinase inhibitors). However, many fusion proteins involved in various cellular processes have not been studied for targeted therapeutics. This is because the lack of complete fusion protein sequences and their whole 3D structures has made it challenging to develop new therapeutic strategies. To fill these critical gaps, we developed a computational pipeline and a resource of human fusion proteins named FusionPDB, available at https://compbio.uth.edu/FusionPDB. FusionPDB is organized into four levels: 43K fusion protein sequences (14.7K in-frame fusion genes, Level 1), over 2300 + 1267 …

To Open Or Not To Open: Developing A Covid-19 Model Specific To Small Residential Campuses, Christina Joy Edholm, Maryann Hohn, Nicole Lee Falicov, Emily Lee, Lily Natasha Wartman, Ami Radunskaya

CODEE Journal

In May 2020, administrators of residential colleges struggled with the decision of whether or not to open their campuses in the Fall semester of 2020. To help guide this decision, we formulated an ODE model capturing the dynamics of the spread of COVID-19 on a residential campus. In order to provide as much information as possible for administrators, the model accounts for the different behaviors, susceptibility, and risks in the various sub-populations that make up the campus community. In particular, we start with a traditional SEIR model and add compartments representing relevant variables, such as quarantine compartments and a hospitalized …

Enrichment Of Polycyclic Aromatic Hydrocarbon Metabolizing Microorganisms On The Oral Mucosa Of Tobacco Users, James V. Defrancesco, Lin Tao, M Paul Chiarelli, Sylvia Pavlova, Antonia Kolokythas, Joel Schwartz, Benjamin Salameh, Stefan J. Green, Guy Adami

Chemistry: Faculty Publications and Other Works

Certain soil microbes resist and metabolize polycyclic aromatic hydrocarbons (PAHs). The same is true for a subset of skin microbes. In the human mouth, oral microbes have the potential to oxidize tobacco PAHs, thereby increasing these chemicals' ability to cause cancer of adjacent epithelium. We hypothesized that we could identify, in smokers, the oral mucosal microbes that can metabolize PAH. We isolated bacteria and fungi that survived long-term in minimal media with PAHs as the sole carbon source, under aerobic conditions, from the oral mucosa in 17 of 26 smokers and two of 14 nonsmokers. Of bacteria genera that survived …

Inpatient Costs Of Treating Patients With Covid-19, Kandice A Kapinos, Richard M Peters, Robert E Murphy, Samuel F Hohmann, Ankita Podichetty, Raymond S Greenberg

Faculty, Staff and Student Publications

IMPORTANCE: With more than 6.2 million hospitalizations due to COVID-19 in the US, recognition of the average hospital costs to provide inpatient care during the pandemic is necessary to understanding the national medical resource use and improving public health readiness and related policies.

OBJECTIVE: To examine the mean cost to provide inpatient care to treat COVID-19 and how it varied through the pandemic waves and by important sociodemographic patient characteristics.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used inpatient-level data from March 1, 2020, to March 31, 2022, extracted from a repository of clinical, administrative, and financial information covering 97% …

Novel Techniques In Imaging Congenital Heart Disease: Jacc Scientific Statement, Ritu Sachdeva, Aimee K Armstrong, Rima Arnaout, Lars Grosse-Wortmann, B Kelly Han, Luc Mertens, Ryan A Moore, Laura J Olivieri, Anitha Parthiban, Andrew J Powell

Faculty, Staff and Students Publications

Recent years have witnessed exponential growth in cardiac imaging technologies, allowing better visualization of complex cardiac anatomy and improved assessment of physiology. These advances have become increasingly important as more complex surgical and catheter-based procedures are evolving to address the needs of a growing congenital heart disease population. This state-of-the-art review presents advances in echocardiography, cardiac magnetic resonance, cardiac computed tomography, invasive angiography, 3-dimensional modeling, and digital twin technology. The paper also highlights the integration of artificial intelligence with imaging technology. While some techniques are in their infancy and need further refinement, others have found their way into clinical workflow …

Winona State University Alumni Blog: 2011-2022, Winona State University

Winona State University Blogs

The Winona State University (WSU) Alumni Blog includes articles and entries from May 2011- August 2022. Note: there may be format coding in the document.

A Comparison Of Machine Learning Surrogate Models Of Street-Scale Flooding In Norfolk, Virginia, Diana Mcspadden, Steven Goldenberg, Binata Roy, Malachi Schram, Jonathan L. Goodall, Heather Richter

Community & Environmental Health Faculty Publications

Low-lying coastal cities, exemplified by Norfolk, Virginia, face the challenge of street flooding caused by rainfall and tides, which strain transportation and sewer systems and can lead to personal and property damage. While high-fidelity, physics-based simulations provide accurate predictions of urban pluvial flooding, their computational complexity renders them unsuitable for real-time applications. Using data from Norfolk rainfall events between 2016 and 2018, this study compares the performance of a previous surrogate model based on a random forest algorithm with two deep learning models: Long Short-Term Memory (LSTM) and Gated Recurrent Unit (GRU). The comparison of deep learning to the random …

A 3d Dlt View Correction Tool For Manual Digitizing: A Cross-Platform Application For Correcting Shifted Image Coordinates Prior To Object Coordinate Reconstruction, William Moynihan

Theses, Dissertations and Capstones

While 3D direct linear transformation is a versatile motion capture method, care must be taken so that the cameras are not bumped or adjusted between the object space calibration phase and the end of video recording. Disturbing the cameras during this time will misalign the view, making the movement data invalid for the associated calibration. The purpose of this study was to design and validate a cross-platform software application for transforming image coordinates from a bumped camera to be compatible with the object space calibration and to determine the relationship between reconstruction error and changes to bumped camera views.

For …

Progression Magazine, 2023-2024, Coastal Carolina University

Progression Magazine

Magazine of the Gupta College of Science at Coastal Carolina University.

Empowering Kokal: A Decolonized, Community-Led Development Model In Homa Bay County, Kenya, Kennedy Miruka

Regis University Student Publications (comprehensive collection)

In Homa Bay County, Kenya, a community-led development initiative called the Power Centre is transforming the fight against poverty and powerlessness. Grounded in principles of decolonization and participatory action, this project addresses the root causes of marginalization by empowering residents of Kokal Village to become active agents of change. Through a robust mixed-methods research approach, the project identifies systemic challenges and leverages existing social networks to build a sustainable, locally-owned model for development. The Power Centre implements a three-pronged strategy, focusing on increasing community participation, strengthening existing groups, and fostering collaborative networks to weave a robust support system. By addressing …

Power Centres: A Collaborative Development Proposal For Addressing Poverty And Related Challenges In Rural Communities In Kenya, Kennedy Okello Miruka, Kennedy Okello Miruka

Regis University Student Publications (comprehensive collection)

In Homa Bay County, Kenya, a community-led development initiative called the Power Centre is transforming the fight against poverty and powerlessness. Grounded in principles of decolonization and participatory action, this project addresses the root causes of marginalization by empowering residents of Kokal Village to become active agents of change. Through a robust mixed-methods research approach, the project identifies systemic challenges and leverages existing social networks to build a sustainable, locally-owned model for development. The Power Centre implements a three-pronged strategy, focusing on increasing community participation, strengthening existing groups, and fostering collaborative networks to weave a robust support system. By addressing …

How Increased Ransomware Attacks Have Impacted Hospitals In The United States, Mackenzie Dotson

Theses, Dissertations and Capstones

Introduction: The healthcare industry, particularly hospitals, have fallen prey to the alarming rise of ransomware attacks. In recent years, highly sophisticated cybergroups, armed with substantial funds and advanced technology, have intensified their focus on hospitals. Despite the advice against it, most hospitals have paid the ransom in order to regain access to their electronic systems and patient data, underlining the severity of these attacks.

Purpose of the Study: The purpose of this research was to evaluate the effects of ransomware attacks on hospitals in the US to determine if the patients were at risk due to hackers withholding patient information …

The Measure Of Efficiency And Effectiveness When Using Artificial Intelligence (Ai) In Radiology, Jordan Watts

Theses, Dissertations and Capstones

Introduction: The use of artificial intelligence in radiology has helped radiologists identify patterns and abnormalities in medical images to diagnose and treat patients. Deep learning and machine learning algorithms have been used to assist physicians in detecting features that are not noticeable to the human eye. The FDA has approved almost 400 AI algorithms for radiology and estimated that the market for AI in medical imaging would grow from $21.48 billion in 2018 to $264.85 billion in 2028.

Purpose of the Study: The purpose of this research was to evaluate the use of artificial intelligence in radiology to determine its …

Winona State University Improving Our World Blog: 2013-2022, Winona State University

Winona State University Blogs

The Winona State University (WSU) Improving Our World Blog articles and entries from September 2013-February 2022. Note: there may be format coding in the document.

Winona State University Rochester Blog:2014-2023, Winona State University

Winona State University Blogs

The Winona State University (WSU) Rochester Blog includes articles and entries from May 2014-March 2023. Note: there may be format coding in the document.

Winona State University Campus Life Blog: 2013-2022, Winona State University

Winona State University Blogs

The Winona State University (WSU) Campus Life Blog includes articles and entries from October 2013- October 2022. Note: there may be format coding in the document.