Medicine and Health Sciences Commons^™

A Comparative Analysis Of Source Identification Algorithms, Pablo A. Curiel

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematical Modeling Of Immune Response To Sars-Cov-2, Hwayeon Ryu

Biology and Medicine Through Mathematics Conference

No abstract provided.

Incorporating Awareness, Misinformation And Optimal Control In A Model Of Sars-Cov-2, Eric Numfor

Biology and Medicine Through Mathematics Conference

No abstract provided.

Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr

Biology and Medicine Through Mathematics Conference

No abstract provided.

Topological Data Analysis Of Molecular Dynamics Simulations Of Monoclonal Antibodies, Melinda Kleczynski, Christina Bergonzo, Anthony Kearsley

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Stochastic Multi-Host Model For West Nile Virus: Determining The Probability Of Disease Extinction!, Suzanne Robertson

Biology and Medicine Through Mathematics Conference

No abstract provided.

Stochastic Immunology Model And Its Analysis, Rahnuma Islam, David Swigon

Biology and Medicine Through Mathematics Conference

No abstract provided.

Clustering Using Self Organizing Maps In Biology, Olcay Akman

Biology and Medicine Through Mathematics Conference

No abstract provided.

Decoding Immune Cell Navigation: Integrating Artificial Life Modeling With Tumor Microenvironment Dynamics, Sadegh Marzban

Biology and Medicine Through Mathematics Conference

No abstract provided.

Plenary: Mathematics Of Malaria Transmission Dynamics: The Renewed Quest For Eradication, Abba Gumel

Biology and Medicine Through Mathematics Conference

No abstract provided.

Plenary: Insights Into Depression: Mathematical Approaches, Janet Best

Biology and Medicine Through Mathematics Conference

No abstract provided.

The Palestinian Feature Film "200 Meters" Addresses The Issue Of The Apartheid Wall, Samar Abd Al Karim Farahat

Middle East Journal of Communication Studies

This study aimed to explain the methods of processing the Palestinian feature film" 200 meters " to the issue of the apartheid wall, using sub-objectives highlighting political, social and psychological issues and topics in addition to the characters and cinematic elements, to identify the form of processing carried out by the film in an integrated manner. Given the nature of this study, which aimed to find out how the 200-meter film dealt with the issue of the apartheid wall, the researcher adopted the most appropriate approach to studying this type of phenomena, which is the analytical approach. The results of …

Youth Interest In Reusable Menstrual Hygiene Products: An Opportunity For Improving Menstruation Management, Makenna R. Eccles

College Honors Program

Adolescents experience inconsistent menstrual hygiene material access that is exacerbated by poverty and results in menstruation management difficulty, health risks, and interruptions to school attendance. The study centered the adolescent menstruation management experience through qualitative interviews to identify management difficulties and to assess knowledge, interest, and perceived feasibility of implementing reusable menstrual hygiene materials such as reusable sanitary pads, period underwear, menstrual cups, and menstrual disks to improve both menstrual hygiene access and menstrual management experiences. Inductive and deductive coding was used to analyze interview data and identify key themes. Adolescents expressed interest in reusable menstrual hygiene materials due to …

Inchi Isotopologue And Isotopomer Specifications, Hunter N. B. Moseley, Philippe Rocca-Serra, Reza M. Salek, Masanori Arita, Emma L. Schymanski

Markey Cancer Center Faculty Publications

This work presents a proposed extension to the International Union of Pure and Applied Chemistry (IUPAC) International Chemical Identifier (InChI) standard that allows the representation of isotopically‑resolved chemi‑ cal entities at varying levels of ambiguity in isotope location. This extension includes an improved interpretation of the current isotopic layer within the InChI standard and a new isotopologue layer specification for representing chemical intensities with ambiguous isotope localization. Both improvements support the unique isotopically‑ resolved chemical identification of features detected and measured in analytical instrumentation, specifically nuclear magnetic resonance and mass spectrometry.

Scientific contribution

This new extension to the InChI standard …

05.13.2024 Orsp Connect, Liz Williamson

ORED Newsletter

Distinguished Research and Creative Achievement Award, Center for Practical Ethics, DARPA Connect, Air Force Internship

Ankle Mobility And Balance In A Healthy College-Aged Population: A Correlational Study, Anna Johnson, Maddy Roiger, Ellie Stewart, Leah Jackson

Science Symposium

This study aimed to investigate the relationship between ankle mobility and balance in a young, healthy population, filling a gap in existing literature primarily focused on older adults. The findings revealed no significant correlation between ankle mobility and balance measures in the college-aged subjects. While previous research in elderly populations suggested a link between ankle mobility and balance, this study suggests that such a relationship may not hold true for younger individuals. These results underscore the importance of considering age-related differences and overall health status when exploring factors affecting balance, potentially guiding future research and intervention strategies aimed at improving …

Spectral Characterization Of High-Speed Sers Fluctuations, Makayla Schmidt, Emily A. Farley, Marit A. Engevik, Alexandre G. Brolo, Nathan Lemke, Nathan Lindquist

Science Symposium

The concept of plasmonic “hotspots” is central to the broad field of nanophotonics. In surface-enhanced Raman scattering (SERS), hotspots can increase Raman scattering efficiency by orders of magnitude. Hotspot dimensions may range from a few nanometers down to the atomic scale and are able to generate SERS signals from single molecules. However, these single-molecule SERS signals often show significant fluctuations, and the concept of intense, localized, yet static hotspots has come into question. Recent experiments have shown these SERS intensity fluctuations (SIFs) to occur over an extremely wide range of timescales, from seconds to micro-seconds, due to the various physical …

Statistical Approaches For The Early Detection Of Colorectal Cancer Using Longitudinal Biomarkers, Emily Berry

Statistical Science Theses and Dissertations

Colorectal cancer (CRC) is the third leading cause of cancer-related death in the United States [45]. CRC is believed to advance from adenomatous polyps creating a unique opportunity for both early detection and cancer prevention [4, 23]. Like other diseases, CRC screening reduces mortality by detecting cancer at earlier, more treatable stages; however, it can also reduce incidence through the removal of precancerous lesions [4]. As a result, screening is recommended for average-risk adults ≥ 45 years of age and includes a variety of tests [4, 12]. Despite alternate screening options, colonoscopy capacity is often cited as a barrier to …

The Santa Clara, 2024-05-10, Santa Clara University

The Santa Clara

No abstract provided.

Mitochondria Regulate Proliferation In Adult Cardiac Myocytes, Gregory B Waypa, Kimberly A Smith, Paul T Mungai, Vincent J Dudley, Kathryn A Helmin, Benjamin D Singer, Clara Bien Peek, Joseph Bass, Lauren Nelson, Sanjiv J Shah, Gaston Ofman, J Andrew Wasserstrom, William A Muller, Alexander V Misharin, G R Scott Budinger, Hiam Abdala-Valencia, Navdeep S Chandel, Danijela Dokic, Elizabeth Bartom, Shuang Zhang, Yuki Tatekoshi, Amir Mahmoodzadeh, Hossein Ardehali, Edward B Thorp, Paul T Schumacker

Faculty, Staff and Student Publications

Newborn mammalian cardiomyocytes quickly transition from a fetal to an adult phenotype that utilizes mitochondrial oxidative phosphorylation but loses mitotic capacity. We tested whether forced reversal of adult cardiomyocytes back to a fetal glycolytic phenotype would restore proliferative capacity. We deleted Uqcrfs1 (mitochondrial Rieske iron-sulfur protein, RISP) in hearts of adult mice. As RISP protein decreased, heart mitochondrial function declined, and glucose utilization increased. Simultaneously, the hearts underwent hyperplastic remodeling during which cardiomyocyte number doubled without cellular hypertrophy. Cellular energy supply was preserved, AMPK activation was absent, and mTOR activation was evident. In ischemic hearts with RISP deletion, new cardiomyocytes …

How Financial Beliefs And Behaviors Influence The Financial Health Of Individuals Struggling With Opioid Use Disorder, James R Langabeer, Francine R Vega, Marylou Cardenas-Turanzas, A Sarah Cohen, Karima Lalani, Tiffany Champagne-Langabeer

Faculty, Staff and Student Publications

The surge in opioid use disorder (OUD) over the past decade escalated opioid overdoses to a leading cause of death in the United States. With adverse effects on cognition, risk-taking, and decision-making, OUD may negatively influence financial well-being. This study examined the financial health of individuals diagnosed with OUD by reviewing financial beliefs and financial behaviors. We evaluated quality of life, perceptions of financial condition during active use and recovery, and total debt. We distributed a 20-item survey to 150 individuals in an outpatient treatment program for OUD in a large metropolitan area, yielding a 56% response rate. The results …

High-Density Genetic Map Construction And Qtl Mapping Of A Zigzag-Shaped Stem Trait In Tea Plant (Camellia Sinensis), Dingding Liu, Yuanyuan Ye, Rongjin Tang, Yang Gong, Si Chen, Chenyu Zhang, Piao Mei, Jiedan Chen, Liang Chen, Chunlei Ma

Faculty, Staff and Student Publications

The highly unique zigzag-shaped stem phenotype in tea plants boasts significant ornamental value and is exceptionally rare. To investigate the genetic mechanism behind this trait, we developed BC1 artificial hybrid populations. Our genetic analysis revealed the zigzag-shaped trait as a qualitative trait. Utilizing whole-genome resequencing, we constructed a high-density genetic map from the BC1 population, incorporating 5,250 SNP markers across 15 linkage groups, covering 3,328.51 cM with an average marker interval distance of 0.68 cM. A quantitative trait locus (QTL) for the zigzag-shaped trait was identified on chromosome 4, within a 61.2 to 97.2 Mb range, accounting for a phenotypic …

Adapting And Evaluating A Theory-Driven, Non-Pharmacological Intervention To Self-Manage Pain, Jennifer Kawi, Chao Hsing Yeh, Lauren Grant, Johannes Thrul, Hulin Wu, Paul J Christo, Lorraine S Evangelista

Faculty, Staff and Student Publications

BACKGROUND: The existing literature has limited detail on theory-driven interventions, particularly in pain studies. We adapted Bandura's self-efficacy framework toward a theory-driven, non-pharmacological intervention using auricular point acupressure (APA) and evaluated participants' perceptions of this intervention on their pain self-management. APA is a non-invasive modality based on auricular acupuncture principles.

METHODS: We mapped our study intervention components according to Bandura's key sources of self-efficacy (performance accomplishments, vicarious experience, verbal persuasion, and emotional arousal) to facilitate the self-management of pain. Through a qualitative study design, we conducted virtual interviews at one and three months after a 4-week APA intervention among 23 …

Developing And Validating A Nomogram For Early Predicting The Need For Intestinal Resection In Pediatric Intussusception, Yuan-Yang Yu, Jia-Jie Zhang, Ya-Ting Xu, Zheng-Xiu Lin, Shi-Kun Guo, Zhong-Rong Li, Hui-Ya Huang, Xiao-Zhong Huang

Faculty, Staff and Student Publications

PURPOSE: Develop and validate a nomogram for predicting intestinal resection in pediatric intussusception suspecting intestinal necrosis.

PATIENTS & METHODS: Children with intussusception were retrospectively enrolled after a failed air-enema reduction in the outpatient setting and divided into two groups: the intestinal resection group and the non-intestinal resection group. The enrolled cases were randomly selected for training and validation sets with a split ratio of 3:1. A nomogram for predicting the risk of intestinal resection was visualized using logistic regression analysis with calibration curve, C-index, and decision curve analysis to evaluate the model.

RESULTS: A total of 547 cases were included …

05.06.2024 Orsp Connect, Liz Williamson

ORED Newsletter

Library Faculty Win NIH Award, Uniform Guidance Updates,

Heavy Metals In Afforested Mangrove Sediment From The World's Largest Delta: Distributional Mapping, Contamination Status, Risk Assessment And Source Tracing, Md Saifur Rahman, Moshiur Rahman, Yeasmin N Jolly, Md Kamal Hossain, Sanjida Afrin Semme, Bilal Ahamad Paray, Takaomi Arai, Jimmy Yu, M Belal Hossain

Faculty, Staff and Student Publications

This study aims to assess seasonal and spatial variations, contamination status, ecological risks, and metal sources (Ni, Pb, Cr, Cu, Mn, and Zn) in human-afforested mangrove sediments in a deltaic region. Five sampling locations were sampled during dry and wet seasons. Heavy metal concentrations followed the order: Mn > Zn > Ni > Cr > Cu > Pb. Metal loads, except Cu and Pb, were higher during the dry season, aligning with national and international recommendations. Sediment quality guidelines, contamination factor, geoaccumulation index, enrichment factors, and pollution load index indicated uncontaminated sediment in both seasons. Potential ecological risk assessment showed low risk conditions in all …

Accuracy Of Machine Learning To Predict The Outcomes Of Shoulder Arthroplasty: A Systematic Review, Amir H. Karimi, Joshua Langberg, Ajith Malige, Omar Rahman, Joseph A. Abboud, Michael A. Stone

Department of Orthopaedic Surgery Faculty Papers

BACKGROUND: Artificial intelligence (AI) uses computer systems to simulate cognitive capacities to accomplish goals like problem-solving and decision-making. Machine learning (ML), a branch of AI, makes algorithms find connections between preset variables, thereby producing prediction models. ML can aid shoulder surgeons in determining which patients may be susceptible to worse outcomes and complications following shoulder arthroplasty (SA) and align patient expectations following SA. However, limited literature is available on ML utilization in total shoulder arthroplasty (TSA) and reverse TSA.

METHODS: A systematic literature review in accordance with PRISMA guidelines was performed to identify primary research articles evaluating ML's ability to …

Identifying Phytoremediation Performing Plant Species That Can Be Utilized In The Improvement Of Heavy Metal Contaminated Soils, Ashley Clark*, Samuel Mutiti

Graduate Research Showcase

Heavy metal pollution is a problem associated with industrialization and development. Two major metals that are commonly mined and can enter the environment, which can jeopardize communities’ health, are copper (Cu) and lead (Pb). There are different options for reducing heavy metal pollution in the environment via remediation efforts, including physical, chemical, and biological methods. However, physical and chemical remediation can be costly and labor-intensive, making them unsuitable for regions that do not have the funds to utilize these practices. Biological remediation is a more cost-conservative practice that has been shown in many studies to be effective in the gradual …

Bioactive Glass Bead Characterization: Further Applications In Passive Drug Delivery, Marie O. Sykes

Physics and Astronomy Honors Papers

Bioactive glass beads were discovered for their bone repair properties in 1969. This properties, along with their bactericidalness, high ability to be engineered, bioactiveness and their versatile structures, mark them as excellent candidates for explorations in other biomedical applications in addition to bone repair. One alternative application includes passive drug delivery, especially when the biomaterial is in a porous, microsphere structure. In this work, we first explore various samples of bioactive glass compositions and structures in order to target the best bead for the application of drug delivery. The targeted beads are then thoroughly characterized using optical microscopy, Scanning Electron …

Zeolitic Imidazolate Framework-8 Encapsulated With Mo-Based Polyoxometalates As Surfaces With Antibacterial Activity Against Escherichia Coli, Mariam M. Abdelkhalek, Aya M. Mohamed, Rehab Z. Abdallah, Ghada E. Khedr, Rania Siam, Nageh K. Allam

Faculty Journal Articles

Bacterial infections represent a major global health concern, causing millions of deaths and a significant economic burden. The development of antibacterial nanoporous surfaces with potential mechano-bactericidal effects can revolutionize infection control practices. In this study, a hybrid material of zeolitic imidazolate framework-8 (ZIF-8) doped with phosphomolybdic acid (PMA) was synthesized and characterized by field emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and N2 sorption isotherms. PMA@ZIF-8 performance as an antibacterial agent against E. coli was superior to that of its individual constituents, suggesting a synergistic effect of PMA and ZIF-8. The …