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Articles 43531 - 43560 of 45149

Full-Text Articles in Medicine and Health Sciences

Medicolegal Aspects Of Blood-Urine Toluene And Urinary Ortho-Cresol Concentrations In Toluene Exposure, Serap A. Akgür, Pembe Öztürk, Yusuf Kurtulmuş, Hüseyi̇n Karali̇, Süheyla Ertürk Jan 2001

Medicolegal Aspects Of Blood-Urine Toluene And Urinary Ortho-Cresol Concentrations In Toluene Exposure, Serap A. Akgür, Pembe Öztürk, Yusuf Kurtulmuş, Hüseyi̇n Karali̇, Süheyla Ertürk

Turkish Journal of Medical Sciences

Toluene is a widely used solvent in different industrial areas and has a depressant effect on the central nervous system. In medicolegal cases, for the possible influence of toluene on actions or conditions prior to death, a reliable indicator of exposure must be precisely investigated. We developed an appropriate method for toluene analysis and investigate the blood-urine toluene levels and urinary ortho-cresol levels in toluene-exposed workers. Blood and urine toluene levels from 50 male subjects were detected by Gas Chromatography-FID (GC-FID) using the head-space method, and urinary o-cresol levels, a metabolite of toluene, were analyzed by GC. The significance of …


Thalamic Hemorrhage (Presentation And Prognosis Of Hemorrhages), Şule Bi̇len, Selçuk Çomoğlu, Yaşar Şahi̇n, Şenay Özbakir Jan 2001

Thalamic Hemorrhage (Presentation And Prognosis Of Hemorrhages), Şule Bi̇len, Selçuk Çomoğlu, Yaşar Şahi̇n, Şenay Özbakir

Turkish Journal of Medical Sciences

The thalamus is one of the most vulnerable areas for intracerebral hemorrhages. In this study, we investigated the parameters of thalamic hemorrhage such as risk factors, initial complaints, neurologic findings and the prognostic effects of the presence or absence of ventricular penetration, as well as the volume and size of hematoma. A total of 57 patients with thalamic hemorrhage, whose diagnosis was confirmed by cranial computerized tomography, were evaluated. The most significant risk factor was hypertension, while the most common initial clinic symptom was incontinence. Those patients who had small hemorrhagic size of low volume and the presence of ventricular …


Large Loop Excision Of The Transformation Zone: An Outpatient Procedure, Mehmet Rafet Gazvani, Özkan Öztürk Jan 2001

Large Loop Excision Of The Transformation Zone: An Outpatient Procedure, Mehmet Rafet Gazvani, Özkan Öztürk

Turkish Journal of Medical Sciences

A prospective, observational study was carried out to assess the efficacy of Large Loop Excision of the Transformation Zone (LLETZ) as an outpatient procedure during the first visit of patients with abnormal cervical smears. One hundred and seven women were treated with LLETZ under local anaesthesia as an outpatient procedure at their first visit. All patients were followed up routinely with colposcopy, cytology, and also histology where appropriate for at least 6 months. In all cases, the specimens obtained were adequate for histopathological assessment, and in 103 cases (96%), the lesion had been completely excised. When compared, the degree of …


Serum Triglyceride And Lipoprotein-Cholesterol Levels In Patients With And Without Luteal Phase Defect, Hi̇kmet Hassa, Ömer T. Yalçin, Atti̇la Yildirim, H. Mete Tanir, Özgül Paşaoğlu, Mi̇ne İnan Jan 2001

Serum Triglyceride And Lipoprotein-Cholesterol Levels In Patients With And Without Luteal Phase Defect, Hi̇kmet Hassa, Ömer T. Yalçin, Atti̇la Yildirim, H. Mete Tanir, Özgül Paşaoğlu, Mi̇ne İnan

Turkish Journal of Medical Sciences

Objective: To evaluate the serum triglyceride and lipoprotein-cholesterol levels in subjects with and without luteal phase defect. Method: Early follicular and midluteal phase serum triglycerides, lipoprotein-cholesterol and progesterone levels were assessed in 19 subjects with and in 73 subjects without luteal phase defect. The criterion for diagnosis of luteal phase defect was histological development of endometrium delayed for more than 2 days according to the chronological day. The data were analyzed by paired and unpaired t tests, Chi-square test and correlation analysis. Results: The early follicular serum triglyceride and lipoprotein-cholesterol levels of the two groups were similar (p>0.05). The …


Frequency Of Use Of The Various Classes Of Removable Partial Dentures And Selection Of Major Connectors And Direct / Indirect Retainers, Fi̇li̇z Keyf Jan 2001

Frequency Of Use Of The Various Classes Of Removable Partial Dentures And Selection Of Major Connectors And Direct / Indirect Retainers, Fi̇li̇z Keyf

Turkish Journal of Medical Sciences

Selecting the individually suitable form of and location for the major connectors in partially edentulous patients is important. The purpose of classifying removable partial dentures (RPDs) is to simplify identification. Classification also allows for a longitudinal comparison of various classes of RPDs as well as the determination of whether the teaching of RPD design is consistent with the relative frequencies of RPD use. This study surveyed the various types of RPDs being fabricated in a dental laboratory and compared those findings with the data from a previous study. Results indicated that mandibular RPDs are more common than maxillary RPDs, and …


Paget's Disease Of The Male Breast - A Case Report, Sema Hücümenoğlu, Handan Kaya, Fati̇h Mehmet Avşar Jan 2001

Paget's Disease Of The Male Breast - A Case Report, Sema Hücümenoğlu, Handan Kaya, Fati̇h Mehmet Avşar

Turkish Journal of Medical Sciences

ÜMENOĞLU^1 Handan KAYA^2 Fatih Mehmet AVŞAR^3 ^1Department of Pathology, SSK Ankara Training and Research Hospital, Ankara, ^2Department of Pathology, Faculty of Medicine, Marmara University, Istanbul, ^3Department of 1st Surgery, Ankara Numune Training and Research Hospital, Ankara - TURKEY


A Case Of Bisatellited-Isodicentric Supernumerary Chromosome 15, Y. Selma Süngü, Bi̇rsen Karaman, E. Ferda Perçi̇n, Sevi̇m Balci, İlhan Sezgi̇n Jan 2001

A Case Of Bisatellited-Isodicentric Supernumerary Chromosome 15, Y. Selma Süngü, Bi̇rsen Karaman, E. Ferda Perçi̇n, Sevi̇m Balci, İlhan Sezgi̇n

Turkish Journal of Medical Sciences

SÜNGÜ^1 Birsen KARAMAN^2 E. Ferda PERÇİN^1 Sevim BALCI^3 İlhan SEZGİN^1 ^1Department of Medical Biology and Genetics, Faculty of Medicine, Cumhuriyet University 58140-Sivas, ^2Department of Medical Genetics, Faculty of Medicine, Istanbul University, Çapa -Istanbul, ^3Department of Pediatrics, Faculty of Medicine, Hacettepe University Ankara - TURKEY


Nitric Oxide I: Advances In The Measurements For Clinical Applications, Ayşe Baysal Jan 2001

Nitric Oxide I: Advances In The Measurements For Clinical Applications, Ayşe Baysal

Turkish Journal of Medical Sciences

Nitric oxide (NO) is a colorless gas with high affinity to ferrous hemoproteins. This simple molecule is a powerful messenger in the body. This study reviews a literature search using keywords and abstracts in English through Medline. Recent advances in the therapeutic uses of inhaled nitric oxide in lung diseases and other pathologic states urges the efficient and convenient use of nitric oxide in hospital practice. In addition, methods of inhaled nitric oxide delivery, chemiluminescence and electrochemical analyzers were reviewed. The performance characteristics of different equipment were compared. The novel methods of nitric oxide measurements that utilize simple and cheaper …


Colicin Production And Colicin Typing Of Uropathogenic Escherichia Coli, Ayli̇n İmren Çarikçi, Güner Coşar Jan 2001

Colicin Production And Colicin Typing Of Uropathogenic Escherichia Coli, Ayli̇n İmren Çarikçi, Güner Coşar

Turkish Journal of Medical Sciences

Colicins are bactericidal macromolecules in protein structures and they are produced by some strains of Escherichia coli and Shigella, which are members of the Enterobacteriaceae. They have a bactericidal effect on the same species or closely related bacteria, but have no effect on the strains which produce them. In this study, 129 E. coli strains isolated from urine samples of patients in Izmir and Manisa were examined for colicin production, and the colicinogenic strains were examined for their colicin types by means of Horak specific indicator strains. Indicator strains were obtained from the National Type Culture Collection Hygiene and Epidemiology …


Antifungal Activities Of Different Extracts And Echimidine-N-Oxide From Symphytum Sylvaticum Boiss. Subsp. Sepulcrale (Boiss. & Bal.) Greuter & Burdet Var. Sepulcrale, Murat Kartal, Semra Kurucu, Muhammad I. Choudary Jan 2001

Antifungal Activities Of Different Extracts And Echimidine-N-Oxide From Symphytum Sylvaticum Boiss. Subsp. Sepulcrale (Boiss. & Bal.) Greuter & Burdet Var. Sepulcrale, Murat Kartal, Semra Kurucu, Muhammad I. Choudary

Turkish Journal of Medical Sciences

Antifungal activity was determined by the tube dilution method on different extracts of Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. sepulcrale. The antifungal activity of the isolated compound from the root alkaloid fraction (Echimidine-N-Oxide) was also tested against ten fungal cultures. The activity was found to be mainly due to Echimidine-N-Oxide (ENO). The quantitative determination of ENO was also carried out with capillary gas chromatography in the roots and the aerial parts of the plant.


Human Herpesvirus 8 (Hhv-8) In Non-Hiv Associated Forms Of Kaposi's Sarcoma From Turkey, Ni̇lgün Şentürk, Sedef Şahi̇n, Serpi̇l Erci̇ş, Tanil Kocagöz, Ni̇lgün Atakan Jan 2001

Human Herpesvirus 8 (Hhv-8) In Non-Hiv Associated Forms Of Kaposi's Sarcoma From Turkey, Ni̇lgün Şentürk, Sedef Şahi̇n, Serpi̇l Erci̇ş, Tanil Kocagöz, Ni̇lgün Atakan

Turkish Journal of Medical Sciences

Objective: Kaposi's sarcoma (KS), first described in 1872 by Moritz Kaposi, is a spindle cell, multifocal vascular tumor. Despite the intense work on the pathogenesis of KS, its etiology remains in doubt. The aim of this study was to determine the presence of HHV-8 sequences in non-HIV associated Kaposi's sarcoma patients, namely classical and immunosuppression-associated, and compare the results with normal healthy subjects. Materials and Methods: Nineteen patients with classical Kaposi's sarcoma (CKS), and nine patients with immunosuppression-associated Kaposi's sarcoma (ISKS) (6 renal transplantation, 1 Behçet's disease, 1 high grade lymphoma, 1 ataxia telangiectasia) were included in this study. Skin …


Detection Of Human Papilloma Virus In Benign, Malignant And Pre-Cancerous Lesions Of Oral Mucosa By In Situ Hybridization, Mehmet Yaltirik, Ayla Özveren, Canan Alatli, Nevi̇n Büyükakyüz Jan 2001

Detection Of Human Papilloma Virus In Benign, Malignant And Pre-Cancerous Lesions Of Oral Mucosa By In Situ Hybridization, Mehmet Yaltirik, Ayla Özveren, Canan Alatli, Nevi̇n Büyükakyüz

Turkish Journal of Medical Sciences

HPV is an epitheliotropic virus, predominantly associated with human skin and mucosal lesions. In many studies, the presence of HPV types 6/11, 16/18 and 31/33/51 have been demonstrated in oral lesions. The aim of this study is to investigate the presence of specific types of HPV in oral benign and precancerous epithelial lesions and oral carcinomas, and the etiological significance of HPV in oral epithelial malignancies. In the present study, twenty oral lesions, of which seven were papilloma, seven squamous cell carcinoma, four leukoplakia and two lichen planus, were tested for different types of HPV. In addition, these patients were …


Expression Of Fas Antigen And Bcl-2 Protein In Liver Tissues Of Patients With Chronic Hepatitis B, Ayşe Polat, Fazi̇let Kayaselçuk, Reyhan Eği̇lmez, İlhan Tuncer Jan 2001

Expression Of Fas Antigen And Bcl-2 Protein In Liver Tissues Of Patients With Chronic Hepatitis B, Ayşe Polat, Fazi̇let Kayaselçuk, Reyhan Eği̇lmez, İlhan Tuncer

Turkish Journal of Medical Sciences

The aim of this study was to evaluate the role of apoptosis in chronic hepatitis B, and correlate it with disease severity. We studied the expression of the Fas antigen (FasAg) and Bcl-2 protein in a group of patients with chronic hepatitis B at various stages of the disease. Four liver biopsy specimens taken from the patients with chronic hepatitis B infection and five control liver tissue specimens with normal histology were studied. Liver specimens were scored for disease severity according to Knodell's hepatic activity index (HAI). The percentage of hepatic expression was evaluated semi-quantitively. Our immunohistochemical study showed that …


Effects Of Oral L-Glutamine, Insulin And Laxative On The Severity Of Acute Pancreatitis, Fati̇h Mehmet Avşar, Mustafa Şahi̇n, Oral Saygun, İ. Hakan Özel, Süleyman Hengi̇rmen, Hüsametti̇n Vatansev, Ertuğrul Kafali, Osman Yilmaz Jan 2001

Effects Of Oral L-Glutamine, Insulin And Laxative On The Severity Of Acute Pancreatitis, Fati̇h Mehmet Avşar, Mustafa Şahi̇n, Oral Saygun, İ. Hakan Özel, Süleyman Hengi̇rmen, Hüsametti̇n Vatansev, Ertuğrul Kafali, Osman Yilmaz

Turkish Journal of Medical Sciences

Aim: To investigate the effects of oral L-glutamine, insulin and laxative on the severity of acute pancreatitis. Materials and Methods: Forty adult male Sprague-Dawley rats were divided into 4 groups. Experimental pancreatitis was induced by ligating the main biliopancreatic duct. All groups were given standard rat pellets and tap water. In addition Group II was given 15 mg/kg/day of L-glutamine via a catheter enterally, Group III was given a 3 ml/day fleet enema via a catheter enterally, and Group IV was given 3 IU/kg/day of NPH insulin via a catheter enterally. The rats were sacrificed 96 hours after the induction …


Comparison Of Remifentanil-Propofol And Sevoflurane For Preventing Cardiovascular Response And Quality Of Recovery In Paediatric Otolaryngologic Surgery, Zeli̇ha Özer Koçak, Ali̇ Aydin Altunkan, Şebnem Atici, İsmai̇l Ci̇nel, Uğur Oral Jan 2001

Comparison Of Remifentanil-Propofol And Sevoflurane For Preventing Cardiovascular Response And Quality Of Recovery In Paediatric Otolaryngologic Surgery, Zeli̇ha Özer Koçak, Ali̇ Aydin Altunkan, Şebnem Atici, İsmai̇l Ci̇nel, Uğur Oral

Turkish Journal of Medical Sciences

As the practice of outpatient paediatric surgery advances, the search continues for anaesthesia that provides rapid smooth induction, stable patient haemodynamics, rapid emergence and minimal unpleasant side effects. Therefore, this study was designed to compare the haemodynamic changes, emergence and recovery characteristics of remifentanil-propofol (TIVA) and sevoflurane anaesthesia for adenoidectomy with bilateral myringotomy and insertion of tubes and/or tonsillectomy (ENT surgery) in children. Children aged 6.3±1.6 years, undergoing elective ENT surgery, were randomly assigned to receive TIVA (n=15) and sevoflurane (n=15). In both groups, anaesthesia was induced with propofol and remifentanil and maintained either with infusion of propofol-remifentanil or sevoflurane …


Sublingual Valsartan In Hypertensıve Urgency, Yüksel Gökel, Sai̇me Paydaş, Güven Kuvandik, Nazan Alparslan Jan 2001

Sublingual Valsartan In Hypertensıve Urgency, Yüksel Gökel, Sai̇me Paydaş, Güven Kuvandik, Nazan Alparslan

Turkish Journal of Medical Sciences

The objective of this study was to assess the effect of sublingual valsartan in a group of patients with hypertensive urgency. Forty-one patients with hypertensive urgency and systolic blood pressure >200 mmHg, diastolic blood pressure >100 mmHg were studied in an emergency room. Supine blood pressure readings were taken and the patients were given 80 mg of valsartan sublingually. Blood pressure and heart rate were recorded at 15 min intervals over a 90 min period. Systolic blood pressure decreased from 211.22±14.65 mmHg to 158.17±15.48 mmHg, diastolic blood pressure dropped from 120.12±13.44 mmHg to 93.05±6.01 mmHg. The differences were statistically significant. …


Reconstruction Of Temporomandibular Joint Using Distraction Osteogenesis, Reha Ş. Ki̇şni̇şçi̇, Doğan Dolanmaz, Hakan H. Tüz Jan 2001

Reconstruction Of Temporomandibular Joint Using Distraction Osteogenesis, Reha Ş. Ki̇şni̇şçi̇, Doğan Dolanmaz, Hakan H. Tüz

Turkish Journal of Medical Sciences

KİŞNİŞCİ^1 Doğan DOLANMAZ^2 Hakan H. TÜZ^1 ^1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ankara University, Ankara ^2Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Selçuk University, Konya-TURKEY


Adenomyoma Of The Stomach Accompanying Gastric Adenocarcinoma, Sema Hücümenoğlu, Musa Zorlu, Hakan Güzel, Fati̇h Mehmet Avşar Jan 2001

Adenomyoma Of The Stomach Accompanying Gastric Adenocarcinoma, Sema Hücümenoğlu, Musa Zorlu, Hakan Güzel, Fati̇h Mehmet Avşar

Turkish Journal of Medical Sciences

ÜMENOĞLU^1 Musa ZORLU^2 Hakan GÜZEL^2 Fatih Mehmet AVŞAR^3 Departments of ^1Pathology, ^2General Surgery, SSK Ankara Training and Research Hospital, ^3Department of General Surgery, Ankara Numune Training and Research Hospital, Ankara - TURKEY


Leptin And Mast Cells: A Novel Adipoimmune Link, Mariana Hristova, Luigi Aloe, Peter I. Ghenev, Marco Fiore, George N. Chaldakov Jan 2001

Leptin And Mast Cells: A Novel Adipoimmune Link, Mariana Hristova, Luigi Aloe, Peter I. Ghenev, Marco Fiore, George N. Chaldakov

Turkish Journal of Medical Sciences

HRISTOVA^1 Luigi ALOE^2 Peter I. GHENEV^3 Marco FIORE^2 George N. CHALDAKOV^4 ^1Endocrinology Clinic, Medical University, Varna, Bulgaria, ^2Institute of Neurobiology, CNR, Rome, Italy, ^3Department of General and Clinical Pathology and ^4Division of Electron Microscopy, Department of Forensic Medicine, Medical University, Varna, Bulgaria


Teucrium Polium Inhibits Nerve Conduction And Carrageenan Induced Inflammation In The Rat Skin, Jumah Shakhanbeh, O. Adigüzel Jan 2001

Teucrium Polium Inhibits Nerve Conduction And Carrageenan Induced Inflammation In The Rat Skin, Jumah Shakhanbeh, O. Adigüzel

Turkish Journal of Medical Sciences

The effects of acute and chronic perineural treatment of the rat saphenous nerve with Teucrium polium (L.) extract on the conduction property of primary afferent nerve fibers and carrageenan-induced skin inflammation were studied. Direct application of 2.0% T. polium extract to the nerve trunk caused immediate complete inhibition of compound action potentials (CAPs) of all types of primary afferent nerve fibers. Partial recovery of CAPs was seen in up to 37.5% of Aab-fibers, 30.4% of Ad-fibers and 32.4% for C-fibers over one hour after removal of the extract. Fifteen to twenty days after a single perineural application of 2% T. …


The Antioxidant Activity Of The Leaves Of Cydonia Vulgaris, Ali̇ Yildirim, Müni̇r Oktay, Vahi̇t Bi̇laloğlu Jan 2001

The Antioxidant Activity Of The Leaves Of Cydonia Vulgaris, Ali̇ Yildirim, Müni̇r Oktay, Vahi̇t Bi̇laloğlu

Turkish Journal of Medical Sciences

The antioxidant activities of water, ethanol, and ether extracts of the leaves of Cydonia vulgaris Pers. were determined by the thiocyanate method. The antioxidant activity of water extract was increased with the increasing amount of extract (200 µg-1000µg) added to the linoleic acid emulsion. Ether extract was the most effective antioxidant among the extracts. Like antioxidant activity, the reducing power of water extract was concentration dependent. However, ethanol extract was the highest in reducing power, and ether extract was the lowest. The results obtained in the present study indicate that the leaves of Cydonia vulgaris are a potential source of …


Difficulties Associated With The Study Of Action Potential After-Potentials In Rat Cultured Sensory Neurones, Ahmet Ayar, Roderick H. Scott Jan 2001

Difficulties Associated With The Study Of Action Potential After-Potentials In Rat Cultured Sensory Neurones, Ahmet Ayar, Roderick H. Scott

Turkish Journal of Medical Sciences

We investigated the properties of action potential after-potentials in cultured dorsal root ganglion neurones from neonatal rats using the whole cell patch clamp technique. The aims of this study were to characterize after-potentials and investigate the possible influences of Ca^{2+}-induced Ca^{2+}release (CICR) on neuronal excitability. The reversal potentials of action potential after-depolarizations and after-hyperpolarizations were estimated. Although evidence for both Ca^{2+}-activated chloride and potassium conductances was obtained, the data indicated that the after-potentials were contaminatied by a variety of distinct ionic events. Apamin was used to attenuate potassium conductances and appeared to enhance the after-depolarizations due to Ca^{2+}-activated chloride conductances. …


A Relation Between The Apolipoprotein E Genotypes And Microalbuminuria In Type 2 Diabetes Mellitus, Ersi̇n Akarsu, İbrahi̇m Pi̇ri̇m, İlyas Çapoğlu, Hasan Kaya, Güngör Akçay, Necdet Ünüvar Jan 2001

A Relation Between The Apolipoprotein E Genotypes And Microalbuminuria In Type 2 Diabetes Mellitus, Ersi̇n Akarsu, İbrahi̇m Pi̇ri̇m, İlyas Çapoğlu, Hasan Kaya, Güngör Akçay, Necdet Ünüvar

Turkish Journal of Medical Sciences

Various relations between apolipoprotein E (apo E) and diabetic nephropathy have been reported. In this study, the question of whether there is any relation between apo E genotypes and microalbuminuria in patients with type-2 diabetes mellitus was examined. Twenty-one male and 25 female patients, with ages the range of 37-62 years (mean 51.7±7.5) with type-2 diabetes mellitus were studied. The apo E genotypes were determined by PCR amplification of the 227 bp region followed by CfoI digestion to release specific band patterns. While 24 patients had microalbuminuria (microalbuminuria group), 22 patients had normoalbuminuria (normoalbuminuria group). The patients with microalbuminuria had …


Expression Of The 8 Kda Heat Shock Protein (Ubiquitin) In Psoriasis, İbrahi̇m Pi̇ri̇m, Teoman Erdem, Necmetti̇n Akdeni̇z, Yaşar Nuri̇ Şahi̇n Jan 2001

Expression Of The 8 Kda Heat Shock Protein (Ubiquitin) In Psoriasis, İbrahi̇m Pi̇ri̇m, Teoman Erdem, Necmetti̇n Akdeni̇z, Yaşar Nuri̇ Şahi̇n

Turkish Journal of Medical Sciences

The 8kDa protein (ubiquitin) is a member of the small heat shock protein (hsb) family. Ubiquitin may additionally be involved in the pathogenesis of various diseases. Intracellular accumulation of ubiquitin has been detected in patients with neurodegenerative disease, brain ischemia, cancer, rheumatoid arthritis and haemodialysis. Sixteen biopsy samples from patients with psoriasis who were treated by PUVA and the same samples from these patients before PUVA treatment were investigated by immunohistochemistry on formalin-fixed paraffin- embedded tissue sections, using anti-ubiquitin antibody. In psoriatic epidermis, ubiquitin was mostly expressed in basal layers with a cytoplasmic staining pattern. Various cells of the dermis …


Pulmonary Infections Due To Legionella Pneumophila In Immunocompromised Patients, Demet Kaya, Si̇nan Ergi̇nel, Muzaffer Meti̇ntaş, Zeki̇ Üstüner, İrfan Uçgun, Necla Özdemi̇r Jan 2001

Pulmonary Infections Due To Legionella Pneumophila In Immunocompromised Patients, Demet Kaya, Si̇nan Ergi̇nel, Muzaffer Meti̇ntaş, Zeki̇ Üstüner, İrfan Uçgun, Necla Özdemi̇r

Turkish Journal of Medical Sciences

The numbers of immunocom-promised individuals increase as programmes for organ transplantation and chemotherapy of malignant disease advance. Pulmonary infections, which progress rapidly, are one of the major clinical problems in these groups. This study was designed to evaluate the microbiology of pneumonia in immunocompromised patients and to determine the role of Legionella pneumophila. Immunocompromised patients receiving antineoplastic chemotherapy, diagnosed as pneumonia with clinical and radiographic findings and routine laboratory tests were included in the study. For microbiological diagnosis, expectorated sputum was cultured for L. pneumophila. In addition to standard bacterial, fungal and mycobacterial media, specimens were examined microscopically. Direct flourescent …


Perioperative Oral Supplement With Immunonutrients In Gastrointestinal Cancer Patients, Ni̇hal Zeki̇ye Erdem, İ. Hakan Kulaçoğlu, Mehtap Akci̇l Temel, Ahmet Çinar Yasti, Nuri̇ Aydin Kama, Nazan Bozkurt Jan 2001

Perioperative Oral Supplement With Immunonutrients In Gastrointestinal Cancer Patients, Ni̇hal Zeki̇ye Erdem, İ. Hakan Kulaçoğlu, Mehtap Akci̇l Temel, Ahmet Çinar Yasti, Nuri̇ Aydin Kama, Nazan Bozkurt

Turkish Journal of Medical Sciences

Significant benefits have been gained with pre or peri-operative nutritional support in surgical patients with malnutrition. Recent studies have also shown that some enteral formulas including certain nutrients like glutamine could provide more benefit than the standard formulas. In this prospective-randomized study, the effects of perioperative oral supplement with enteral formulas containing glutamine in comparison with a standard enteral formula in patients who were operated on for GI malignancies were examined. Thirty-two patients were divided into two groups: the study group was given oral supplement with an elemental diet (Alitraq®) for 7 days preoperatively and 10 days postoperatively as 30-35% …


Observations Of The Changes Occurring In The Rat Trachea Due To Inhalation Of Cigarette Smoke, Aysel Kükner, Hakan Öner, Neri̇man Çolakoğlu, Jale Öner, Enver Ozan, Sema Ozan, Seval Yilmaz Jan 2001

Observations Of The Changes Occurring In The Rat Trachea Due To Inhalation Of Cigarette Smoke, Aysel Kükner, Hakan Öner, Neri̇man Çolakoğlu, Jale Öner, Enver Ozan, Sema Ozan, Seval Yilmaz

Turkish Journal of Medical Sciences

In this study, the tracheal tissues of rats inhaling cigarette smoke passively during different periods were examined by light and electron microscopy. Malonaldehyde, erythrocyte catalase and arginase levels were also measured. Three groups were formed and a total of 15 Wistar male rats weighing 200-250 g were used. Rats assigned to the first and second groups were made to inhale cigarette smoke for 30 and 60 minutes respectively for a total of 3 months. The subjects in the third group were made to inhale clean air as a control. Cigarettes without filter tips were used througout the study. Lit cigarettes …


Smooth Muscle Actin (Sma) Immunoreactivity In Primary Glomerulonephritis (Gn), Duygu Düşmez, Gülfi̇li̇z Gönlüşen, Emel Akoğlu, Sevgi̇ Küllü, İlhan Tuncer Jan 2001

Smooth Muscle Actin (Sma) Immunoreactivity In Primary Glomerulonephritis (Gn), Duygu Düşmez, Gülfi̇li̇z Gönlüşen, Emel Akoğlu, Sevgi̇ Küllü, İlhan Tuncer

Turkish Journal of Medical Sciences

The aims of this study were to determine the role of interstitial and glomerular myofibroblasts in the progression of various glomerulonephritis, and to assess the value of myofibroblasts in determining long-term renal outcome. The biopsy specimens of 42 primary glomerulonephritis cases were reviewed and stained immunohistochemically with alpha smooth muscle actin antibody. The serum creatine level was compared to the pathological changes. The interstitial alpha smooth muscle actin staining correlated with the serum creatine level at the time of biopsy. The glomerular staining, conversely, did not show any relation with renal function. Interstitial myofibroblasts play a role in the development …


A Study On The Rat Stapedial Artery Under The Dissection Microscope, Cahi̇de Ortuğ Jan 2001

A Study On The Rat Stapedial Artery Under The Dissection Microscope, Cahi̇de Ortuğ

Turkish Journal of Medical Sciences

The stapedial artery is a rare anomaly in man. However, an undetected persistence of the artery may cause problems during middle ear surgery. The studies on its course are inadequate. The aim of the present paper is to describe the course of the stapedial artery in rats, through an examination under a dissection microscope.


The Effect Of Sulfur Dioxide On T-Butyl Hydroperoxide Induced Oxidative Stress In Lung Tissues Of Rats, Saadet Gümüşlü, Di̇jle Ki̇pmen Korgun, Süreyya Bi̇lmen, Gülteki̇n Yücel, Pi̇raye Yargiçoğlu, Aysel Ağar Jan 2001

The Effect Of Sulfur Dioxide On T-Butyl Hydroperoxide Induced Oxidative Stress In Lung Tissues Of Rats, Saadet Gümüşlü, Di̇jle Ki̇pmen Korgun, Süreyya Bi̇lmen, Gülteki̇n Yücel, Pi̇raye Yargiçoğlu, Aysel Ağar

Turkish Journal of Medical Sciences

In this study, the effects of sulfur dioxide (SO_2) ,a common pollutant in urban air, on t-butyl hydroperoxide-induced oxidative stress in rat lung tissues were examined. Ten young rats and 10 adult rats were exposed to SO_2 while another 10 young rats and 10 adult rats made up the control groups. Ten ppm SO_2 was administered to the animals of the SO_2 groups in an exposure chamber for one hour a day every day for 6 weeks. The control groups were exposed to filtered air in the same chamber for the same period. At the end of the experimental period, …