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Articles 43501 - 43530 of 45149

Full-Text Articles in Medicine and Health Sciences

Sandwich-Type Enzyme Immunoassay For Amyloid A4 Protein In Cerebrospinal Fluid From Patients With Head Trauma, İbrahi̇m Pi̇ri̇m Jan 2001

Sandwich-Type Enzyme Immunoassay For Amyloid A4 Protein In Cerebrospinal Fluid From Patients With Head Trauma, İbrahi̇m Pi̇ri̇m

Turkish Journal of Medical Sciences

The aim of this study was to design a simple method for detecting the amyloid A4 protein in the cerebrospinal fluid (CSF) of patients who had severe brain trauma caused by traffic or other accidents and to evaluate its diagnostic and prognostic value. For this purpose, a sandwich type ELISA assay was used. A4, a 4kDa protein of 39-43 amino acids, is a metabolic product of a membrane-spanning, 695-770 aa, precursor molecule, the b-amyloid precursor protein (b-APP). The polyclonal rabbit antibody against synthetic A4 protein (1-40 residues) was used as an immobilized antibody. A mouse monoclonal antibody against synthetic A4 …


Efficacy Of Some Disinfectants On Embryonated Eggs Of Toxocara Canis, Hasan Ayçi̇çek, Ender Yarsan, H. Oğuz Sarimehmetoğlu, Mehmet Tanyüksel, Nogay Gi̇rgi̇nkardeşler, Mustafa Özyurt Jan 2001

Efficacy Of Some Disinfectants On Embryonated Eggs Of Toxocara Canis, Hasan Ayçi̇çek, Ender Yarsan, H. Oğuz Sarimehmetoğlu, Mehmet Tanyüksel, Nogay Gi̇rgi̇nkardeşler, Mustafa Özyurt

Turkish Journal of Medical Sciences

The aim of this study was to evaluate the efficacy of various disinfectants in different concentrations against embryonated Toxocara canis eggs. For this purpose, 2.5%, 5%, 7.5%, and 10% iodine, 2% glutaraldehyde, 10% benzalkonium chloride, 7% sodium hypochloride, 1% potassium permanganate, 70% ethyl alcohol, 10% potassium hydroxide and 3% phenol solutions were used as the disinfectants. This study was performed both in vitro and in-vivo. In the in vitro experiment, T. canis eggs were treated with disinfectant solutions in different time intervals, and larval motility was observed under X400 magnification with an inverted microscope. Microscopic examinations revealed that T. canis …


Relationship Between Aging And Susceptibility To Oxidative Damage: An Assessment By Erythrocyte Membrane Proteins And Lipids, Ahmet Özaydin, İlhan Onaran, Kadi̇r Avşar, Vecdet Tezcan, Gönül Sultuybek Jan 2001

Relationship Between Aging And Susceptibility To Oxidative Damage: An Assessment By Erythrocyte Membrane Proteins And Lipids, Ahmet Özaydin, İlhan Onaran, Kadi̇r Avşar, Vecdet Tezcan, Gönül Sultuybek

Turkish Journal of Medical Sciences

Contradictory results have been reported from various studies regarding the effect of age on susceptibility to oxidative damage. Using different parameters, we carried out a comparative study on the erythrocytes and erythrocyte membranes of healthy elderly and young adults to determine how resistance to oxidative damage is affected by aging. Thin layer chromatography and polyacrylamide gel electrophoresis under denaturing conditions were used to estimate changes in membrane phospholipids and cytoskeletal proteins, respectively. Our results showed that these components of intact erythrocytes incubated with cumene hydroperoxide (CumOOH), a powerful oxidising agent, remained unchanged in both age groups. However, exposure of erythrocyte …


Department Of Radiation Oncology And Kimmel Cancer Center, Thomas Jefferson University, The Intronic G13964c Variant In P53 Is Not A High-Risk Mutation In Familial Breast Cancer In Australia., Anna Marsh, Amanda B Spurdle, Bruce C Turner, Sian Fereday, Heather Thorne, Gulietta M Pupo, Graham J Mann, John L Hopper, Joseph F Sambrook, Georgia Chenevix-Trench Jan 2001

Department Of Radiation Oncology And Kimmel Cancer Center, Thomas Jefferson University, The Intronic G13964c Variant In P53 Is Not A High-Risk Mutation In Familial Breast Cancer In Australia., Anna Marsh, Amanda B Spurdle, Bruce C Turner, Sian Fereday, Heather Thorne, Gulietta M Pupo, Graham J Mann, John L Hopper, Joseph F Sambrook, Georgia Chenevix-Trench

Department of Radiation Oncology Faculty Papers

BACKGROUND: Mutations in BRCA1 and BRCA2 account for approximately 50% of breast cancer families with more than four affected cases, whereas exonic mutations in p53, PTEN, CHK2 and ATM may account for a very small proportion. It was recently reported that an intronic variant of p53--G13964C--occurred in three out of 42 (7.1%) 'hereditary' breast cancer patients, but not in any of 171 'sporadic' breast cancer control individuals (P = 0.0003). If this relatively frequent occurrence of G13964C in familial breast cancer and absence in control individuals were confirmed, then this would suggest that the G13964C variant plays a role in …


Are Inflammatory Cytokines Potential Mediators Of Phenytoin-Induced Gingival Overgrowth?, Nurcan Buduneli̇, Gül Ati̇lla, Neci̇l Kütükçüler Jan 2001

Are Inflammatory Cytokines Potential Mediators Of Phenytoin-Induced Gingival Overgrowth?, Nurcan Buduneli̇, Gül Ati̇lla, Neci̇l Kütükçüler

Turkish Journal of Medical Sciences

The levels of interleukin-1beta, tumour necrosis factor-alpha, and interleukin 6 in gingival crevicular fluid of phenytoin-treated patients (from sites exhibiting overgrowth and sites not exhibiting overgrowth) and control subjects were investigated. Six epileptic patients exhibiting severe phenytoin-induced gingival overgrowth, 12 patients with chronic gingivitis and 11 subjects with clinically healthy periodontium were included in the study. The cytokine levels were analysed by enzyme-linked immunosorbent assay and expressed as ng/2 sites. Wilcoxon signed-rank test, Kruskall-Wallis, Mann-Whitney U test and Spearman rank correlation were used for statistical analysis of the data. Overgrown sites showed significantly higher levels of interleukin-1beta compared to the …


The Effect Of Moderate +Gz Force On The Cervical Spine Bone Mineral Density In Raaf Pc-9 Pilots, Meghan C. Grant Jan 2001

The Effect Of Moderate +Gz Force On The Cervical Spine Bone Mineral Density In Raaf Pc-9 Pilots, Meghan C. Grant

Theses : Honours

Previous research on exercise and bone mineral density (BMD) has established that increases in BMD are site specific, responding to unusual strain and particularly to high magnitude loading. The positive Gz forces generated during high performance flying provide all three variables. Naumann, Bennell and Wark (2000) investigated the effects of moderate gravitational force on the BMD of fighter pilots. The pilots in this study had significant increases in BMD and bone mineral content (BMC) for the thoracic spine, pelvis and total body. However, it is now suspected that the cervical spine, which was unable to be analysed at that time …


Production Of Monoclonal Antibody Specific For Human Hemoglobin, Selma Öztürk, Beyazit Çirakoğlu Jan 2001

Production Of Monoclonal Antibody Specific For Human Hemoglobin, Selma Öztürk, Beyazit Çirakoğlu

Turkish Journal of Medical Sciences

Hemoglobin is not normally present in sputum, urine or feces except in minute amounts. Demonstration of the presence of hemoglobin in these materials is an important diagnostic clue that usually implies bleeding within the respiratory, urinary or gastroentestinal tract, respectively. In this work, a hybridoma line secreting monoclonal antibody (Mab) highly specific for human hemoglobin A (hHbA) was generated by fusion of immunized BALB/c mouse splenic lymphocytes with non-secreting mouse myeloma cells followed by selection in hypoxanthine-aminopterin-thymidine (HAT) medium and the screening of culture fluids for hHb A affinity in ELISA. The Mab produced by MAM 2/3B6 is highly specific …


Flow Cytometric Analysis Of The Effects Of Methotrexate And Vepesid On The Hep-2 Cell Cycle, Ni̇zami̇ Duran, Adi̇l M. Allahverdi̇yev, Sali̇h Çeti̇ner Jan 2001

Flow Cytometric Analysis Of The Effects Of Methotrexate And Vepesid On The Hep-2 Cell Cycle, Ni̇zami̇ Duran, Adi̇l M. Allahverdi̇yev, Sali̇h Çeti̇ner

Turkish Journal of Medical Sciences

Objective: To determine the mechanism of action of Methotrexate and Vepesid on the HEp-2 cells isolated from human laryngeal cancer cells morphologically and flow cytometrically (G1, G2, S and PI). Materials and Methods: The HEp-2 continuous cell line was used. Cultivation of the cells was realized in EMEM medium with 10% fetal bovine serum at an atmosphere of 37ºC with 5% CO_2. Six different concentrations of Vepesid and Methotrexate were prepared by diluting with deionized water (5 µg/ml, 50 mg/ml, 500 µg/ml). The morphological and cell cycle parameters of HEp-2 cells were determined by inverted microscope and flow cytometer respectively. …


In Vitro Mic Determination Of Haemophilus Influenzae Strains Using E-Test, Ni̇lay Çöplü, Orhan Cem Aktepe, Selda Uluutku, Engi̇n Güvener Jan 2001

In Vitro Mic Determination Of Haemophilus Influenzae Strains Using E-Test, Ni̇lay Çöplü, Orhan Cem Aktepe, Selda Uluutku, Engi̇n Güvener

Turkish Journal of Medical Sciences

H. influenzae is a fastidious bacteria, so the selection of a reliable method for in-vitro susceptibility tests is particularly important. The E-test is a practical method for detecting in-vitro antimicrobial susceptibility of antibiotics by MIC values. This study was performed using the E-test for direct patient management and in order to obtain epidemiological data on H. influenzae. The detection of antimicrobial agent resistance among fifty-seven H. influenzae isolates from lower respiratory tract infections in childhood was studied by the E-test. The E-test was performed on HTM agar according to the instruction manual recommendations. The susceptibility ratios and the MIC90 values …


Effects Of Experimental Diabetes And Insulin Treatment On Rabbit Renal Morphology: A Quantitative And Qualitative Study, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu, Celal Kaloğlu, Öztürk Özdemi̇r, Semi̇h Ayan Jan 2001

Effects Of Experimental Diabetes And Insulin Treatment On Rabbit Renal Morphology: A Quantitative And Qualitative Study, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu, Celal Kaloğlu, Öztürk Özdemi̇r, Semi̇h Ayan

Turkish Journal of Medical Sciences

Diabetes causes metabolic defects and related vascular alterations such as atherosclerosis. These vascular alterations may also reflect the renal structural degeneration under the influence of diabetes. Therefore, the aim of the present study was to determine qualitatively and quantitatively the effect of experimental diabetes on rabbit renal cortical structure, and also to evaluate the reversal rate of the renal structural alterations by daily insulin treatment. Eighteen rabbits, bred and fed in standard laboratory conditions, were divided into 3 groups each containing 6 animals. While control group animals received no treatment, the rest were injected with a single dose of intravenous …


Analysis Of Ras Gene Mutation In Human Oral Tumours By Polymerase Chain Reaction And Direct Sequencing, Si̇nan Süzen, James M. Parry Jan 2001

Analysis Of Ras Gene Mutation In Human Oral Tumours By Polymerase Chain Reaction And Direct Sequencing, Si̇nan Süzen, James M. Parry

Turkish Journal of Medical Sciences

Genetic alterations in proto-oncogenes or tumour suppressor genes are believed to be one of the key events in the multistage process of carcinogenesis. Activating point mutations occurring in either one of the three ras proto-oncogene families are common genetic alterations in human and animal neoplasms. However, the mechanisms leading to oral cancer are not completely understood. Activation of the ras oncogene in oral carcinogenesis, although absent or rare in the western world, accounts for up to 35% of all malignancies in India and South Asia. Recognised aetiological agents of oral cancer include tobacco and alcohol. Tobacco-associated compounds such as nitrosamines …


Cytomorphologic Analysis Of Papanicolaou Stained Smears Collected From Floor Of The Mouth Mucosa In Patients With Or Without Oral Malignancy, Nur Mollaoğlu, Jonathan George Cowpe, Rita Walker Jan 2001

Cytomorphologic Analysis Of Papanicolaou Stained Smears Collected From Floor Of The Mouth Mucosa In Patients With Or Without Oral Malignancy, Nur Mollaoğlu, Jonathan George Cowpe, Rita Walker

Turkish Journal of Medical Sciences

Cytology has been found to be a reliable and accurate technique when used to diagnose early malignant transformation in areas of the body where visual examination is difficult or impossible. The factors initiating neoplastic growth are still not clearly understood. Thus, automated instruments, capable of objective and quantitative cell analysis, have been used in descriptive morphology, for the assessment of tumour cell heterogeneity. Smears were collected from a group of 33 patients presenting with squamous cell carcinoma. Nine females and 24 males presenting with squamous cell carcinoma of the floor of the mouth underwent quantitative cytological assessment. These slides were …


Igg Subclass Levels In Elf In Copd, Demet Karnak, Sumru Beder, Oya Kayacan, Levent Karaca Jan 2001

Igg Subclass Levels In Elf In Copd, Demet Karnak, Sumru Beder, Oya Kayacan, Levent Karaca

Turkish Journal of Medical Sciences

Objective: Deficiency of immunoglobulin (Ig) may be responsible for recurrent infections in chronic obstructive pulmonary disease (COPD). Our aim was to investigate the level of IgG subclass (IgGsc) in the epithelial lining fluid (ELF) and to try to find a possible relation between these levels and serum or bronchoalveolar lavage (BAL) IgGsc levels in COPD patients with recurrent acute exacerbation. Methods: Twenty-four clinically stable non-smoking COPD patients who had developed recurrent exacerbations three or four times a year and 17 individuals without COPD were enrolled as the experimental and control groups (Group I and II) respectively. The BAL procedure was …


Glomerular Hla Dr Dp Dq Expression In Renal Diseases, Sülen Sarioğlu, Feza Kirimca, Caner Çavdar, Mehmet Türkmen Jan 2001

Glomerular Hla Dr Dp Dq Expression In Renal Diseases, Sülen Sarioğlu, Feza Kirimca, Caner Çavdar, Mehmet Türkmen

Turkish Journal of Medical Sciences

The expression of major histocompatibility antigens class II (MHC II) in renal diseases has been studied extensively in the tubulo-interstitial compartment, while there are few articles about their expression in the glomeruli. In this series, glomerular expression of HLA DR DP DQ is evaluated in a total of 62 cases of pyelonephritis, glomerulonephritis, tubulointerstitial nephritis and systemic diseases with renal manifestations in order to identify their relationship with disease status and renal scarring. Formaline fixed paraffin embedded tissue sections from renal biopsy and nefrectomy specimens were stained by an antibody against HLA DR DP DQ by the streptavidin biotin method. …


Determination Of The Absorption Of Zn By Preterm Infants, Using 70zn Enriched Tracer, Ulvi̇ Ulusoy, John E. Whitley Jan 2001

Determination Of The Absorption Of Zn By Preterm Infants, Using 70zn Enriched Tracer, Ulvi̇ Ulusoy, John E. Whitley

Turkish Journal of Medical Sciences

Absorption of zinc by preterm infants from a synthetic milk labelled extrinsically with 70Zn tracer was determined by faecal monitoring. Six male preterm babies with a mean gestational age of 31±2.9 weeks and a mean birth weight of 1.23±0.24 kg were studied for three balance periods of 72 h with intervals ranging from 6 to 30 days. The babies were fed with the milk containing zinc with added 70Zn tracer. The net (NA) and true (TA) absorption, and endogenous loss (EL) of zinc were determined by the classical (chemical) balance and isotopic approaches. The mean TA, NA and EL were …


A Comparative Clinical And Histopathological Examination Of Hemangioma And Chronic Inflammatory Enlargement Of Gingiva, Umur Sakallioğlu, Gökhan Açikgöz, Tuğrul Kirtiloğlu, Musa Aldikaçti Jan 2001

A Comparative Clinical And Histopathological Examination Of Hemangioma And Chronic Inflammatory Enlargement Of Gingiva, Umur Sakallioğlu, Gökhan Açikgöz, Tuğrul Kirtiloğlu, Musa Aldikaçti

Turkish Journal of Medical Sciences

Chronic inflammatory gingival enlargement (CIGE) occasionally exhibits some similarities with hemangioma (Hm) by means of the clinical and histopathological features of gingiva. When compared with hemangioma, CIGE is more frequently encountered by the dental profession. However, Hm is rarely seen on gingiva and it has a non-inflammatory nature and mostly congenital origin. The present paper reports the clinic and histopathologic features of CIGE and Hm of gingiva in patients referred to our clinic suffering primarily from gingival overgrowth. Twenty-one patients were diagnosed as having CIGE (in a 4-month period) and 10 patients were diagnosed as having Hm (in a 12-month …


The Effects Of Tooth Extraction On Cortical Thickness And Bone Mineral Density Of The Mandible: Evaluation With Computerized Tomography, Pinar Polat, Gözlem Ceylan, Selami̇ Suma, Nuran Yanikoğlu Jan 2001

The Effects Of Tooth Extraction On Cortical Thickness And Bone Mineral Density Of The Mandible: Evaluation With Computerized Tomography, Pinar Polat, Gözlem Ceylan, Selami̇ Suma, Nuran Yanikoğlu

Turkish Journal of Medical Sciences

The cortical thickness of the mandible (CTM) and its bone mineral density may be affected by tooth extraction. There is little knowledge of how the number of teeth in the mandible affect the cortical thickness and bone mineral density of the mandible in 2 different parts. The purpose of this study was to demonstrate whether there is any relationship between the number of teeth extracted and the cortical thickness and bone mineral density of the mandible. A total of 64 cases were evaluated in this study. The patients were divided into four groups. Group 1 consisted of 24 patients who …


A Father Born To Consanguineous Parents Had Double Translocation 21;22 [44,Xy, T(21q;22q), T(21q;22q)] Due To Familial Translocation In Four Generations, Cumhur Gündüz, Ferda Özkinay, Özgür Çoğulu, Gül Sapmaz, Tufan Çankaya, Ci̇hangi̇r Özkinay Jan 2001

A Father Born To Consanguineous Parents Had Double Translocation 21;22 [44,Xy, T(21q;22q), T(21q;22q)] Due To Familial Translocation In Four Generations, Cumhur Gündüz, Ferda Özkinay, Özgür Çoğulu, Gül Sapmaz, Tufan Çankaya, Ci̇hangi̇r Özkinay

Turkish Journal of Medical Sciences

No abstract provided.


The Histopathologic And The Immunohistochemical Features Of Secretory Meningiomas, M. Şerefetti̇n Canda, Meri̇h Güray, D.Ümi̇t Acar Jan 2001

The Histopathologic And The Immunohistochemical Features Of Secretory Meningiomas, M. Şerefetti̇n Canda, Meri̇h Güray, D.Ümi̇t Acar

Turkish Journal of Medical Sciences

No abstract provided.


Cold Shock Proteins, N. Nuray Ulusu, E. Ferhan Tezcan Jan 2001

Cold Shock Proteins, N. Nuray Ulusu, E. Ferhan Tezcan

Turkish Journal of Medical Sciences

From prokaryotes to eukaryotes or from invertebrates to vertebrates, all organisms have developed various adaptive mechanisms to survive within a wide range of growth temperatures. An important part of the cold adaptation mechanism occurs at the level of the cytoplasmic membrane. Cold shock affects the membrane composition and organisation to maintain the optimum membrane function. Cold shock also affects cell division. The temperature downshift results in a growth lag. During the lag phase the organism changes the composition of the cytoplasmic membrane and synthesis sets of specific proteins called cold shock proteins or cold induced proteins.


Effects Of Oral L-Glutamine, Insulin And Laxative On Bacterial Translocation In Acute Pancreatitis, Fati̇h Mehmet Avşar, İ. Hakan Özel, Mahmut Baykan, Oral Saygun, Mustafa Şahi̇n, Süleyman Hengi̇rmen, Ömür Ertuğrul, Mehmet Gürbi̇lek, S. Neşe Aydin Jan 2001

Effects Of Oral L-Glutamine, Insulin And Laxative On Bacterial Translocation In Acute Pancreatitis, Fati̇h Mehmet Avşar, İ. Hakan Özel, Mahmut Baykan, Oral Saygun, Mustafa Şahi̇n, Süleyman Hengi̇rmen, Ömür Ertuğrul, Mehmet Gürbi̇lek, S. Neşe Aydin

Turkish Journal of Medical Sciences

Aim: To investigate the effects of oral L-glutamine, insulin and laxative on the bacterial population of intestinal lumen and on bacterial translocation in acute pancreatitis. Materials and Methods: Forty Sprague-Dawley adult male rats were divided into 4 groups. Experimental pancreatitis was induced by ligating the main biliopancreatic duct. All groups were given the standard rat diet and tap water. In addition, Group II was given. 15 mg/kg/day of L-glutamine via a catheter enterally, Group III was given 3 ml of laxative via a catheter enterally, and Group IV was given 3 IU/kg/day of NPH insulin via a catheter enterally. The …


The Type And Frequency Of Infections Occurring In Collagen Tissue Diseases, Refi̇k Ali̇ Sari, Mehmet Şahi̇n, Göksal Keski̇n, İlhami̇ Ki̇ki̇, Murat Turgay Jan 2001

The Type And Frequency Of Infections Occurring In Collagen Tissue Diseases, Refi̇k Ali̇ Sari, Mehmet Şahi̇n, Göksal Keski̇n, İlhami̇ Ki̇ki̇, Murat Turgay

Turkish Journal of Medical Sciences

Corticosteroids, widely used in the treatment of collagen tissue diseases, increase the number of neutrophils and decrease the total numbers of lymphocytes, monocytes, eosinophils and basophils. In addition, corticosteroids alter important functional activities of both lymphocytes and monocytes. They suppress the bactericidial activities of phagocytes. In this manner, the resistance to infections is reduced. Cytotoxic drugs can have profound effects on the production and function of both phagocyte cells and lymphocytes. We followed up 115 patients with collagen tissue disease for two years and 22 of them had infections. Eight of these 22 patients had urinary tract infection, six had …


Isolated Caudate Nucleus Hemorrhage During The Acute Period Of Stroke, Selçuk Çomoğlu, Şenay Özbakir Jan 2001

Isolated Caudate Nucleus Hemorrhage During The Acute Period Of Stroke, Selçuk Çomoğlu, Şenay Özbakir

Turkish Journal of Medical Sciences

Caudate hemorrhage is a rare stroke syndrome that accounts for only 3-7% of all primary intracerebral hematomas. In this study, we evaluated eight patients with isolated caudate nucleus hemorrhage for their clinical presentation and neurological findings. Material and methods: Eight patients, who were admitted to our department with isolated caudate nucleus hemorrhage, were evaluated for their clinical presentation and present risk factor findings on neurological examination and prognosis. Results: The most common symptoms on admission were headache and vomiting (five patients), whereas the most common findings on neurological examination were unconsciousness and neck stiffness (four patients). Two patients who were …


The Effect Of Fixed Restoration Materials On The Il-1\Beta Content Of Gingival Crevicular Fluid, Jüli̇de Özen, Bedri̇ Beydemi̇r, Muhi̇tti̇n A. Serdar, Mehmet Dalkiz, Işil Saygun, Ati̇lla Özdemi̇r Jan 2001

The Effect Of Fixed Restoration Materials On The Il-1\Beta Content Of Gingival Crevicular Fluid, Jüli̇de Özen, Bedri̇ Beydemi̇r, Muhi̇tti̇n A. Serdar, Mehmet Dalkiz, Işil Saygun, Ati̇lla Özdemi̇r

Turkish Journal of Medical Sciences

Cast alloys used in dentistry come into close and prolonged contact with the gingiva and the oral mucosa, and certain alloys have been claimed to cause inflammation of gingival and periodontal tissues. However, only little information is available on the molecules mediating the mechanism of such an effect. For this reason, the aims of this study were to determine 1L-1\beta levels in the gingival crevicular fluid (GCF) before and after the placement of base, high-noble metal-ceramic and all-ceramic crowns. Thirty patients requiring an artificial crown for a maxillary second premolar were suitable for the present study; 18 were male and …


A Rare Cause Of Upper Gastrointestinal System Bleeding: Pancreatic Endocrine Neoplasm, Oral Saygun, Fati̇h Mehmet Avşar, İ. Hakan Özel, Süleyman Hengi̇rmen, Levent Albayrak, Sema Hücümenoğlu Jan 2001

A Rare Cause Of Upper Gastrointestinal System Bleeding: Pancreatic Endocrine Neoplasm, Oral Saygun, Fati̇h Mehmet Avşar, İ. Hakan Özel, Süleyman Hengi̇rmen, Levent Albayrak, Sema Hücümenoğlu

Turkish Journal of Medical Sciences

No abstract provided.


Lateral Periodontal Cyst, Işil Saygun, Ati̇lla Özdemi̇r, Mükerrem Safali Jan 2001

Lateral Periodontal Cyst, Işil Saygun, Ati̇lla Özdemi̇r, Mükerrem Safali

Turkish Journal of Medical Sciences

No abstract provided.


Effects Of Paf Antagonist Bn52021 On Systemic And Renal Oxidative Stress In Experimentally Induced Obstructive Jaundice, Nusret Akyürek, Mustafa Kerek, Erdoğan M. Sözüer, Murat Alper, Sabahatti̇n Muhtaroğlu, Mustafa Keçeli̇ Jan 2001

Effects Of Paf Antagonist Bn52021 On Systemic And Renal Oxidative Stress In Experimentally Induced Obstructive Jaundice, Nusret Akyürek, Mustafa Kerek, Erdoğan M. Sözüer, Murat Alper, Sabahatti̇n Muhtaroğlu, Mustafa Keçeli̇

Turkish Journal of Medical Sciences

The aim of this study is to investigate the effects of PAF antagonist BN52021 on systemic and renal oxidative stress in experimentally induced obstructive jaundice. A total of 30 Wistar-Albino type rats used in the study were divided into sham, control and study groups, each consisting of ten subjects. A laparotomy was performed on the study and control groups, and the choledochus was ligated and dissected. In the sham group, the choledochus was dissected by laparotomy and not ligated. The subjects in the control group were administered physiological saline intraperiotoneally between the 2^{nd} and 7^{th} days, and subjects in the …


The Effects Of Different Suture Techniques On Wound Healing In Abdominal Wall Closure, Mustafa Şahi̇n, Mehmet Karademi̇r, Şükrü Özer, Fati̇h Mehmet Avşar, Serdar Yol, Osman Çağlayan, Murat Aktan Jan 2001

The Effects Of Different Suture Techniques On Wound Healing In Abdominal Wall Closure, Mustafa Şahi̇n, Mehmet Karademi̇r, Şükrü Özer, Fati̇h Mehmet Avşar, Serdar Yol, Osman Çağlayan, Murat Aktan

Turkish Journal of Medical Sciences

Purpose: The aim this study was to investigate the effects of different suture techniques on the healing of abdominal wall wound. Materials and Methods: 24 male Wistar albino rats were included in this study. The rats were divided into two groups. A 4 cm midline laparatomy was performed after ketamine HCl anesthesia. In Group I, the incision was sutured with 4/0 polypropylene interruptedly and in Group II, the wound was closed with 4/0 polypropylene continuously. The skin was sutured with an interrupted 4/0 silk suture. Then 2 cc of blood was withdrawn for biochemical and hematological tests by cardiac puncture. …


Comparative Histological Analysis Of Hepatitis C Virus With Hepatitis B, Gülen Akyol, Özlem Süer, Cem Sezer Jan 2001

Comparative Histological Analysis Of Hepatitis C Virus With Hepatitis B, Gülen Akyol, Özlem Süer, Cem Sezer

Turkish Journal of Medical Sciences

Aims: Rates of certain histopathologic features were evaluated in hepatitis C and in hepatitis B materials and analyzed statistically in a Turkish population. Method: The presence of lymphoid aggregate, steatosis, ductal lesions, sinusoidal inflammation and portal iron deposition were investigated in 80 hepatitis C and 104 hepatitis B specimens and evaluated using the chi-square test and Fisher's exact test. Pan Band T cell markers were used for lymphoid aggregate analysis. P53 and PCNA were applied for the possible impact of steatosis on cell biology. Results: All mentioned parameters excluding sinusoidal inflammation were found to be higher in hepatitis C samples. …


Allele Frequencıes Of The Humf13b Str Locus In The Çukurova Region, Lale Dönbak, Serpi̇l Salaçi̇n Jan 2001

Allele Frequencıes Of The Humf13b Str Locus In The Çukurova Region, Lale Dönbak, Serpi̇l Salaçi̇n

Turkish Journal of Medical Sciences

In this study, the STR system HumF13B polymorphism and forensic efficiency values were investigated in a population sample from the Çukurova region. The F13B phenotypes were analysed using polyacrylamide gel electrophoresis (PAGE) following a polymerase chain reaction (PCR) and were visualised by silver staining. Allele frequencies were calculated by the gene counting method. Forensic efficiency values were estimated using the obtained gene frequencies of F13B. In this population sample, a total of five alleles, 6, 7, 8, 9 and 10 of F13B, were observed. The calculated frequencies of these alleles were as follows: 6=0.0910; 7=0.0045; 8=0.3273; 9=0.2045; 10=0.3727. In the …