Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

Medical Sciences

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 37501 - 37530 of 45334

Full-Text Articles in Medicine and Health Sciences

Attitudes Towards Influenza Vaccination In High Socioeconomic Status Turkish Parents, Suzan Gündüz, Çi̇ğdem Nüket Yüksel, Hale Bozkurt Aktoprak, Meti̇n Canbal, Mehmet Kaya Jan 2014

Attitudes Towards Influenza Vaccination In High Socioeconomic Status Turkish Parents, Suzan Gündüz, Çi̇ğdem Nüket Yüksel, Hale Bozkurt Aktoprak, Meti̇n Canbal, Mehmet Kaya

Turkish Journal of Medical Sciences

To better understand the knowledge, attitudes, and demographic factors that influence the rate of influenza vaccination among high socioeconomic status parents. Materials and methods: questionnaire exploring the attitudes of parents to the influenza vaccine, and their knowledge about influenza and its vaccination, was given to parents of children from 1 through 16 years of age attending the Turgut Özal University Hospital after the 2011/12 influenza season. Results: In the present study, 285 mothers and their children participated and 8.8% (n = 25) of children had the influenza vaccination. Between the vaccinated and nonvaccinated groups, there were statistically significantly differences for …

Go to article

Hepatitis C Virus Genotypes In Adana And Antakya Regions Of Turkey, Agah Bahadir Öztürk, Ümi̇t Bi̇lge Doğan, Nevi̇n Akçaer Öztürk, Gonca Özyazici, Mehmet Demi̇r, Mustafa Sali̇h Akin, Ali̇ Suha Bi̇ngöl Jan 2014

Hepatitis C Virus Genotypes In Adana And Antakya Regions Of Turkey, Agah Bahadir Öztürk, Ümi̇t Bi̇lge Doğan, Nevi̇n Akçaer Öztürk, Gonca Özyazici, Mehmet Demi̇r, Mustafa Sali̇h Akin, Ali̇ Suha Bi̇ngöl

Turkish Journal of Medical Sciences

Hepatitis C virus (HCV) genotype 1 was found to be dominant in Turkey. In this study, HCV genotypes were examined in the Adana and Antakya regions of Turkey. Materials and methods: The study consisted of 639 HCV-RNA–positive patients with chronic HCV infection in Adana (214 males and 101 females) and Antakya (139 males and 185 females) in Turkey. Real time-polymerase chain reaction was used for genotype determination. Results: In Antakya, it was determined that the percentages of genotypes of type 1a (0.31%), 1b (86.73%), 2 (9.26%), 3 (0.93%), and 4 (2.78%) were compatible with the nationwide results seen in Turkey. …

Go to article

The Relationship Between Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia And Erectile Dysfunction: The Role Of Autonomic Hyperactivity, Mehmet Umul, Ahmet Bariş Altay, Fi̇kret Bademkiran, Burak Turna, Mehmet Bülent Semerci̇, Erdal Apaydin, Necmetti̇n Çikili Jan 2014

The Relationship Between Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia And Erectile Dysfunction: The Role Of Autonomic Hyperactivity, Mehmet Umul, Ahmet Bariş Altay, Fi̇kret Bademkiran, Burak Turna, Mehmet Bülent Semerci̇, Erdal Apaydin, Necmetti̇n Çikili

Turkish Journal of Medical Sciences

To investigate whether autonomic nervous system (ANS) hyperactivity may be a potential cause for the relationship between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED). Materials and methods: Twenty-four patients were recruited for this study. Complete physical examinations, urine analysis, uroflowmetry, and postvoid residual urine volume (PVRU) analysis were performed. The potential impact of some factors such as hyperglycemia, obesity, and hyperlipidemia were analyzed. These values were correlated with the various symptom scores. We performed an electromyographic and an electrocardiographic evaluation. The alterations after treatment with 2 different alpha-blockers were also analyzed. Results: The electromyographic and electrocardiographic assessments revealed …

Go to article

The Effect Of Lateral Internal Sphincterotomy On Resting Anal Sphincter Pressures, Kemal Peker, İsmayi̇l Yilmaz, İsmai̇l Demi̇ryilmaz, Abdullah İnal, Arda Işik Jan 2014

The Effect Of Lateral Internal Sphincterotomy On Resting Anal Sphincter Pressures, Kemal Peker, İsmayi̇l Yilmaz, İsmai̇l Demi̇ryilmaz, Abdullah İnal, Arda Işik

Turkish Journal of Medical Sciences

Anal fissures are one of the most common proctologic disorders. This study aimed to investigate alterations in anal sphincteric resting pressures after lateral internal sphincterotomy, which was performed for chronic anal fissure treatment. Materials and methods: Fifty-six (68.3%) male and 26 (31.7%) female patients were included in this study. Patients complicated with fistula-in-ano, abscess, cancer, inflammatory bowel disease, dermatitis, poor general condition, allergy to any of the standard medications, previous history of anal trauma, previous anal surgery, or diagnosis of a neurological disease and patients who did not give consent to the trial were excluded from the study. Two groups …

Go to article

Early Graft Dysfunction And Mortality Rate In Marginal Donor Liver Transplantation, Pinar Sarkut, Bariş Gülcü, Remzi̇ İşçi̇men, Murat Kiyici, Gürkan Türker, Nai̇le Bolca Topal, Yilmaz Özen, Ekrem Kaya Jan 2014

Early Graft Dysfunction And Mortality Rate In Marginal Donor Liver Transplantation, Pinar Sarkut, Bariş Gülcü, Remzi̇ İşçi̇men, Murat Kiyici, Gürkan Türker, Nai̇le Bolca Topal, Yilmaz Özen, Ekrem Kaya

Turkish Journal of Medical Sciences

To determine the effect of marginal donor livers on mortality and graft survival in liver transplantation (LT) recipients. Materials and methods: Donors with any 1 of following were considered marginal donors: age =>65 years, sodium level =>165 mmol/L and cold ischemia time =>12 h. Donors were classified according to the donor risk index (DRI) 1.7. The transplant recipients' model for end-stage liver disease (MELD) scores were considered low if 20. Early graft dysfunction (EGD) and mortality rate were evaluated. Results: During the study period 47 patients underwent cadaveric LT. The mean age of the donors and recipients …

Go to article

Comparison Of High-Resolution Melting Analysis To Denaturing High Performance Liquid Chromatography In The Detection Of Point Mutations In Mefv, F5, And F2 Genes, Hülya Sümer Çelebi̇, Hi̇lal Özdağ Jan 2014

Comparison Of High-Resolution Melting Analysis To Denaturing High Performance Liquid Chromatography In The Detection Of Point Mutations In Mefv, F5, And F2 Genes, Hülya Sümer Çelebi̇, Hi̇lal Özdağ

Turkish Journal of Medical Sciences

Sensitive and cost-effective detection of point mutations is important in genetics research. Denaturing high-performance liquid chromatography (DHPLC) is known to be one of the most sensitive techniques for point mutation detection. A more recent technique, high-resolution melting (HRM), is based on the melting behavior of PCR products. In this study, the efficiency and sensitivity of HRM and DHPLC for the detection of MEFV, F5, and F2 gene point mutations were evaluated. Materials and methods: We studied 15 patients with MEFV mutations (E148Q, M680I, M694V, or V726A), 7 patients with the F51691G>A mutation, and 12 patients with the F220210G>A …

Go to article

Evaluation And Comparison Of Alpha- And Beta-Amanitin Toxicity On Mcf-7 Cell Line, Ertuğrul Kaya, Recep Bayram, Kürşat Oğuz Yaykaşli, İsmai̇l Yilmaz, Sai̇t Bayram, Emi̇ne Yaykaşli, Muhsi̇ne Zeynep Yavuz, Ali̇ Akçahan Gepdi̇remen Jan 2014

Evaluation And Comparison Of Alpha- And Beta-Amanitin Toxicity On Mcf-7 Cell Line, Ertuğrul Kaya, Recep Bayram, Kürşat Oğuz Yaykaşli, İsmai̇l Yilmaz, Sai̇t Bayram, Emi̇ne Yaykaşli, Muhsi̇ne Zeynep Yavuz, Ali̇ Akçahan Gepdi̇remen

Turkish Journal of Medical Sciences

Alpha- and beta-amanitins are the main toxins of the poisonous Amanita phalloides mushroom. Although there are many studies available concerning alpha-amanitin, there are limited data about beta-amanitin in the literature. Therefore, this study is aimed at comparing the toxic effects of alpha- and beta-amanitin on the MCF-7 cell line. Materials and methods: The alpha- and beta-amanitins used for this research were purified from Amanita phalloides by preparative high-performance liquid chromatography. The MCF-7 breast cancer cell line was used, and specific concentrations of the toxins (100, 10, 1, 0.1, and 0.01 µg/mL) were applied to the cells. The MTT test was …

Go to article

The Effect Of Malaysian Honey And Its Major Components On The Proliferation Of Cultured Fibroblasts, Al-Mahdi Al-Jadi, Francis Kanyang Enchang, Kamaruddi̇n Mohd Yusoff Jan 2014

The Effect Of Malaysian Honey And Its Major Components On The Proliferation Of Cultured Fibroblasts, Al-Mahdi Al-Jadi, Francis Kanyang Enchang, Kamaruddi̇n Mohd Yusoff

Turkish Journal of Medical Sciences

To examine, for the first time, the effect of a selected Malaysian honey and its major components on the proliferation of cultured fibroblasts. Materials and methods: Honey and some of its components, which include the sugars, the proteins, the hydrogen peroxide produced, and the phenolics, were exposed to cultured fibroblasts. The MTT colorimetric assay was used to assess cell viability and proliferation. Results: The stimulatory effect of honey on fibroblast proliferation was observed to be time- and dose-dependent. The continuous production of hydrogen peroxide by the honey-glucose oxidase system also acts to stimulate cell proliferation in a time- and dose-dependent …

Go to article

Molecular Discrimination Of Echinococcus Granulosus And Echinococcus Multilocularis By Sequencing And A New Pcr-Rflp Method With The Potential Use For Other Echinococcus Species, Çağri Şakalar, Sali̇h Kuk, Ahmet Erensoy, Adi̇le Ferda Dağli, İbrahi̇m Hani̇fi̇ Özercan, Ülfet Çeti̇nkaya, Süleyman Yazar Jan 2014

Molecular Discrimination Of Echinococcus Granulosus And Echinococcus Multilocularis By Sequencing And A New Pcr-Rflp Method With The Potential Use For Other Echinococcus Species, Çağri Şakalar, Sali̇h Kuk, Ahmet Erensoy, Adi̇le Ferda Dağli, İbrahi̇m Hani̇fi̇ Özercan, Ülfet Çeti̇nkaya, Süleyman Yazar

Turkish Journal of Medical Sciences

To develop a novel polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) protocol using a new genomic marker sequence and a novel set of restriction enzymes in order to detect and discriminate 2 Echinococcus species, E. granulosus and E. multilocularis, found in formalin-fixed paraffin-embedded (FFPE) human tissues. Materials and methods: DNA was isolated from 11 FFPE human tissue samples positive for cystic echinococcosis or alveolar echinococcosis. A mitochondrial genomic marker region was amplified and sequenced using a novel primer pair and a new PCR-RFLP protocol was developed for the detection and discrimination of E. granulosus and E. multilocularis using a set …

Go to article

Effects Of Ozone Therapy And Taurine On Ischemia/Reperfusion-Induced Testicular Injury In A Rat Testicular Torsion Model, Tolga Reşat Aydos, Mehmet Murad Başar, Oğuz Kul, Hasan Tarik Atmaca, Tuba Uzunali̇oğlu, Üçler Kisa, Oğuzhan Eki̇n Efe Jan 2014

Effects Of Ozone Therapy And Taurine On Ischemia/Reperfusion-Induced Testicular Injury In A Rat Testicular Torsion Model, Tolga Reşat Aydos, Mehmet Murad Başar, Oğuz Kul, Hasan Tarik Atmaca, Tuba Uzunali̇oğlu, Üçler Kisa, Oğuzhan Eki̇n Efe

Turkish Journal of Medical Sciences

To investigate the effect of ozone and/or taurine treatment comparatively on testicular damage due to ischemia/reperfusion (I/R) injury in an experimental torsion model in rats. Materials and methods: Adult Wistar rats with and without torsion/detorsion were used. In order to monitor the effect of ozone and/or taurine treatment on testicular damage due to I/R injury, following histopathological investigation apoptotic indexes were scored by TUNEL method. Moreover, tumor necrosis factor receptor 1 (TNFR1), caspase 3, caspase 8, endothelial nitric oxide synthase (eNOS), tumor necrosis factor alpha (TNF\alpha), and cytochrome C immunostainings were performed and the levels of malondialdehyde, glutathione peroxidase, superoxide …

Go to article

Early Extracorporeal Life Support Experiences In 2 Tertiary Pediatric Intensive Care Units In Turkey, Makbule Ni̇lüfer Öztürk, Koray Ak, Ni̇lgün Erkek, Edanur Yeşi̇l, Muhterem Duyu, Pinar Yazici, Ayşen Yaprak Engi̇n, Bülent Karapinar Jan 2014

Early Extracorporeal Life Support Experiences In 2 Tertiary Pediatric Intensive Care Units In Turkey, Makbule Ni̇lüfer Öztürk, Koray Ak, Ni̇lgün Erkek, Edanur Yeşi̇l, Muhterem Duyu, Pinar Yazici, Ayşen Yaprak Engi̇n, Bülent Karapinar

Turkish Journal of Medical Sciences

Extracorporeal membrane oxygenation (ECMO) is a unique life-support modality offered to patients unresponsive to optimal medical therapy. The aim of this study was to evaluate early experiences with ECMO support in 2 tertiary Turkish pediatric intensive care units (PICUs). Materials and methods: We retrospectively evaluated a total of 10 ECMO-supported patients between March 2012 and March 2013 in Marmara and Ege University Hospital PICUs. We reported data regarding demographics, laboratory and diagnostic information, and the clinical course of the patients. Results: The study consisted of 6 males and 4 females from 5 months to 14 years of age (mean age: …

Go to article

Insulin-Like Growth Factor 1, Liver Enzymes, And Insulin Resistance In Patients With Pcos And Hirsutism, Evri̇m Çakir, Oya Topaloğlu, Nujen Çolak Bozkurt, Başak Karbek Bayraktar, Aşkin Güngüneş, Müyesser Sayki Arslan, İlknur Öztürk Ünsal, Esra Tutal, Beki̇r Uçan, Tuncay Deli̇başi Jan 2014

Insulin-Like Growth Factor 1, Liver Enzymes, And Insulin Resistance In Patients With Pcos And Hirsutism, Evri̇m Çakir, Oya Topaloğlu, Nujen Çolak Bozkurt, Başak Karbek Bayraktar, Aşkin Güngüneş, Müyesser Sayki Arslan, İlknur Öztürk Ünsal, Esra Tutal, Beki̇r Uçan, Tuncay Deli̇başi

Turkish Journal of Medical Sciences

Hyperinsulinemia and insulin resistance are commonly seen in patients with hirsutism and polycystic ovary syndrome (PCOS), and are associated with cardiovascular disease risk. However, it is not yet known whether insulin-like growth factor I (IGF-I) and alanine transaminase (ALT) produced by the liver play roles in hyperinsulinemia and subclinical atherosclerotic process in patients with PCOS and idiopathic hirsutism (IH). Materials and methods: This was a prospective case-controlled study. The study population consisted of 25 reproductive-age PCOS women, 33 women with IH, and 25 control subjects. Results: Mean IGF-I levels and median ALT levels were higher in patients with IH and …

Go to article

Investigating The Effects Of Negative-Calorie Diet Compared With Low-Calorie Diet Under Exercise Conditions On Weight Loss And Lipid Profile In Overweight/Obese Middle-Aged And Older Men, Mohammadreza Rezaeipour, Gennady Leonidovich Apanasenko, Vladimir Ivanovich Nychyporuk Jan 2014

Investigating The Effects Of Negative-Calorie Diet Compared With Low-Calorie Diet Under Exercise Conditions On Weight Loss And Lipid Profile In Overweight/Obese Middle-Aged And Older Men, Mohammadreza Rezaeipour, Gennady Leonidovich Apanasenko, Vladimir Ivanovich Nychyporuk

Turkish Journal of Medical Sciences

Negative-calorie diets (NCDs) are among the popular dieting guides for weight loss; however, there is still little knowledge about this method. The present study aimed to determine the effects of a NCD supplemented with exercise on weight loss and lipid profile, and to compare its efficiency with low-calorie diets (LCDs) with exercise among elderly adult men with abnormal weight gain. Materials and methods: Participants included sedentary men (aged 45-75 years) who were overweight or obese (n = 37). They were randomly divided into 2 groups: a group with a NCD and exercise, and a group with a LCD with exercise. …

Go to article

Airway Inflammation And Tiotropium Treatment In Stable Copd Patients, Duygu Özol, Harun Karamanli, Sema Uysal, Muhammet Ramazan Yi̇ği̇toğlu, Zeki̇ Yildirim Jan 2014

Airway Inflammation And Tiotropium Treatment In Stable Copd Patients, Duygu Özol, Harun Karamanli, Sema Uysal, Muhammet Ramazan Yi̇ği̇toğlu, Zeki̇ Yildirim

Turkish Journal of Medical Sciences

Chronic obstructive pulmonary disease (COPD) is an inflammatory disease of the lung associated with progressive airflow limitation. The aim of this study is to assess the influence of tiotropium treatment on airway inflammation and symptoms in stable COPD patients. Materials and methods: Inflammatory markers were measured in the expired breath condensate fluid (EBC) before starting tiotropium treatment and at the end of the first month. Results: Twenty-two patients (81% men) with a mean age of 65.4 ± 10.1 years completed the study. The mean nitrotyrosine and 8-isoprostane levels for oxidative stress markers in EBC before and after treatment were 4.5 …

Go to article

Leptin And Leptin Receptor Polymorphisms Are Related To Body Mass Index In A Turkish Population, Uzay Görmüş, Özlem Ti̇mi̇rci̇ Kahraman, Bahar Toptaş, Turgay İsbi̇r, Çavlan Çi̇ftçi̇, Hasan Hakan Berkkan, Altay Burak Dalan, Muti̇a Canan Karatay Jan 2014

Leptin And Leptin Receptor Polymorphisms Are Related To Body Mass Index In A Turkish Population, Uzay Görmüş, Özlem Ti̇mi̇rci̇ Kahraman, Bahar Toptaş, Turgay İsbi̇r, Çavlan Çi̇ftçi̇, Hasan Hakan Berkkan, Altay Burak Dalan, Muti̇a Canan Karatay

Turkish Journal of Medical Sciences

Leptin is a hormone that is known to be related to weight gain and obesity. The soluble leptin receptor has been found in plasma as an important determinant of leptin sensitivity. In this study, our goal was to investigate the association between leptin levels and leptin receptor polymorphisms in a Turkish population. Materials and methods: The sample pool of this study consisted of 202 subjects. G2548A variant in the promoter region of the leptin gene and Q223R polymorphism of the leptin receptor gene were evaluated by using PCR-RFLP. Leptin levels were determined by ELISA. Results: Leptin levels were significantly higher …

Go to article

The Relation Between Helicobacter Pylori And Ulcerative Colitis, Sedat Caner, Aki̇f Altinbaş, Yusuf Yeşi̇l, Yavuz Beyazit, Bariş Yilmaz, Osman Yüksel Jan 2014

The Relation Between Helicobacter Pylori And Ulcerative Colitis, Sedat Caner, Aki̇f Altinbaş, Yusuf Yeşi̇l, Yavuz Beyazit, Bariş Yilmaz, Osman Yüksel

Turkish Journal of Medical Sciences

Besides some genetic explanations of the native course of ulcerative colitis (UC), the most attributable factors are pathogenic bacterial agents. There are some conflicting data about the relationship between Helicobacter pylori and the rate of UC in the literature. Therefore, we aimed to investigate the rate of H. pylori in UC patients. Materials and methods: Forty-nine individuals diagnosed with UC who had undergone upper gastrointestinal tract endoscopy for different reasons were included in the study. The presence of H. pylori in the stomach was checked by histopathological examination. Results: H. pylori positivity was present in 57.1% of patients with UC. …

Go to article

The Correlation Of Echo Findings Of Right Cardiac Pathologies With Bnp, Uric Acid, And Crp In Osas, Ömer Araz, Eli̇f Yilmazel Uçar, Hüsnü Deği̇rmenci̇, Di̇dem Pulur, Hami̇t Acemoğlu, Ednan Bayram, Fuat Gündoğdu, Meti̇n Akgün Jan 2014

The Correlation Of Echo Findings Of Right Cardiac Pathologies With Bnp, Uric Acid, And Crp In Osas, Ömer Araz, Eli̇f Yilmazel Uçar, Hüsnü Deği̇rmenci̇, Di̇dem Pulur, Hami̇t Acemoğlu, Ednan Bayram, Fuat Gündoğdu, Meti̇n Akgün

Turkish Journal of Medical Sciences

Right cardiac pathologies develop in patients with obstructive sleep apnea syndrome (OSAS) and in most patients there are no symptoms in the early stages of right cardiac disorders. We aimed to evaluate a possible relationship between B-type natriuretic peptide (BNP), blood uric acid, C-reactive protein (CRP), and the right cardiac pathologies in patients with OSAS, and the role of these parameters in the management of patients with OSAS. Materials and methods: A total of 98 subjects, 31 (31.6%) controls and 67 (68.4%) with OSAS, were included in the study. All the subjects underwent polysomnography, and standard and tissue Doppler echocardiography …

Go to article

Polymorphisms In Mmp-2 And Timp-2 In Turkish Patients With Prostate Cancer, Kürşat Oğuz Yaykaşli, Muhammet Ali̇ Kayikçi, Nesi̇be Yamak, Hati̇ce Soğuktaş, Selma Düzenli̇, Ali̇ Osman Arslan, Ahmet Meti̇n, Ertuğrul Kaya, Ömer Faruk Hati̇poğlu Jan 2014

Polymorphisms In Mmp-2 And Timp-2 In Turkish Patients With Prostate Cancer, Kürşat Oğuz Yaykaşli, Muhammet Ali̇ Kayikçi, Nesi̇be Yamak, Hati̇ce Soğuktaş, Selma Düzenli̇, Ali̇ Osman Arslan, Ahmet Meti̇n, Ertuğrul Kaya, Ömer Faruk Hati̇poğlu

Turkish Journal of Medical Sciences

Prostate cancer is the most commonly diagnosed malignancy and the second most common cause of cancer deaths in the Western male population. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) modulate the remodeling of the extracellular matrix (ECM). The imbalance between MMPs and TIMPs may lead to an emergence of pathological processes such as cancer. In this study, the association between TIMP-2 (-418 G/C) and MMP-2 (-1306 C/T) polymorphisms and prostate cancer in the Turkish population was investigated. Materials and methods: Sixty-one prostate cancer patients and 46 healthy subjects were included in the study. DNA was isolated from 2 …

Go to article

Does Lymph Node Involvement Affect The Patterns Of Recurrence In Stage Ib Cervical Cancer?, Işin Üreyen, Ülkü Aksoy, Betül Dündar, Ömer Lütfi̇ Tapisiz, Mustafa Alper Karalök, Ahmet Taner Turan, Nuretti̇n Boran, Hakki Gökhan Tulunay Jan 2014

Does Lymph Node Involvement Affect The Patterns Of Recurrence In Stage Ib Cervical Cancer?, Işin Üreyen, Ülkü Aksoy, Betül Dündar, Ömer Lütfi̇ Tapisiz, Mustafa Alper Karalök, Ahmet Taner Turan, Nuretti̇n Boran, Hakki Gökhan Tulunay

Turkish Journal of Medical Sciences

To investigate the variations in the recurrence patterns of stage IB cervical cancer according to lymph node involvement. Materials and methods: We reviewed the medical records of 170 patients who had undergone type III radical hysterectomy and systematic lymphadenectomy from 1993 to 2007. Results: Among the patients in the study group, 115 did not have lymph node metastases, whereas 55 did. A total of 27 patients developed recurrences. Twelve were in the lymph node-negative group, and 15 were in the lymph node-positive group. The recurrence rate was higher in lymph node-positive group (27.3% versus 10.4%, P = 0.011). The recurrence …

Go to article

A Case--Ontrol Study Of The Factors Affecting Male Infertility, Mohammad Mahboubi, Fezollah Foroughi, Fariba Ghahramani, Hanieh Shahandeh, Sahar Moradi, Tooraj Shirzadian Jan 2014

A Case--Ontrol Study Of The Factors Affecting Male Infertility, Mohammad Mahboubi, Fezollah Foroughi, Fariba Ghahramani, Hanieh Shahandeh, Sahar Moradi, Tooraj Shirzadian

Turkish Journal of Medical Sciences

Infertility is defined as the inability to conceive after at least 1 year of unprotected intercourse. In about one third of infertile couples, a male factor is the primary problem. Thus, the present study aimed to determine the most common risk factors for male infertility in Iranian men. Materials and methods: This case-control study included 268 men attending an infertility clinic in Shiraz, Iran. In this study, 161 fertile men were compared with 108 infertile ones regarding risk factors such as smoking habits, drug consumption, hernia, varicocele, job, and BMI. The data were analyzed using logistic regression analysis and t-test. …

Go to article

Surgery For Intractable Temporal Lobe Epilepsy: Experience Of A Single Institution, Gökhan Kurt, Mehmet Tönge, Emrah Çelti̇kçi̇, İrem Çapraz, Ayşe Serdaroğlu, Erhan Bi̇li̇r Jan 2014

Surgery For Intractable Temporal Lobe Epilepsy: Experience Of A Single Institution, Gökhan Kurt, Mehmet Tönge, Emrah Çelti̇kçi̇, İrem Çapraz, Ayşe Serdaroğlu, Erhan Bi̇li̇r

Turkish Journal of Medical Sciences

In the treatment of epilepsy, encouraging results have been achieved with surgical treatment, especially for temporal lobe epilepsy (TLE). Drug resistance must be diagnosed as early as possible, because the ensuing seizures can be eliminated surgically via temporal lobe surgery in a high percentage (70%-90%) of patients. In this study we share our experience, in a single institution, of surgical treatment of intractable TLE. Materials and methods: Between March 2006 and November 2010 we performed 127 corticoamygdalohippocampectomy (CAH) procedures. All CAH surgical procedures were done as described by Niemeyer's technique. Resection lengths were 4-4.5 cm from the temporal pole. Results: …

Go to article

Expression And Clinical Implications Of P53, P63, And P73 Protein In Malignant Tumor Of The Parotid Gland, Mei Yong, Ling Yang, Qimuge Suyila, Wenyan Han, Hongwei Yuan, Cheng Zhao, Xiulan Su Jan 2014

Expression And Clinical Implications Of P53, P63, And P73 Protein In Malignant Tumor Of The Parotid Gland, Mei Yong, Ling Yang, Qimuge Suyila, Wenyan Han, Hongwei Yuan, Cheng Zhao, Xiulan Su

Turkish Journal of Medical Sciences

To investigate the expression of P53, P63, and P73 proteins in malignant parotid gland tumors and adjacent nonneoplastic tissues and the association between the 3 proteins and their clinical characteristics. Materials and methods: A total of 40 pairs of paraffin-embedded malignant parotid gland tumors and adjacent nonneoplastic tissues were collected. We detected P53, P63, and P73 protein expression by immunohistochemistry. Statistical analysis was performed by using the chi-square test. Results: P53, P63, and P73 protein expression in malignant parotid gland tumors was higher than their expression in adjacent nonneoplastic tissue (P = 0.030, 0.001, and 0.001, respectively). Expression of P53, …

Go to article

Comparative Study Of Photodynamic Therapy Monotherapy Versus Triple Management In Age-Related Macular Degeneration, Ahmet Seli̇m, Ni̇lüfer Koçak, Hüseyi̇n Aslankara, Süleyman Kaynak Jan 2014

Comparative Study Of Photodynamic Therapy Monotherapy Versus Triple Management In Age-Related Macular Degeneration, Ahmet Seli̇m, Ni̇lüfer Koçak, Hüseyi̇n Aslankara, Süleyman Kaynak

Turkish Journal of Medical Sciences

To compare the effectiveness of photodynamic therapy (PDT) and PDT combined with intravitreal triamcinolone (IVTA) and vascular endothelial growth factor inhibition (anti-VEGF) in age-related macular degeneration (AMD). Materials and methods: Eighty eyes of 80 patients diagnosed with choroidal neovascularization (CNV) caused by AMD were included in the study. PDT was carried out on 40 eyes in group I, and PDT combined with 4 mg IVTA and anti-VEGF (1.25 mg bevacizumab in 20 eyes, 0.3 mg pegaptanib sodium in 20 eyes) was carried out in group II. The primary efficacy endpoint was the mean change from baseline visual acuity at month …

Go to article

Early Surgical Results Of A 23-Gauge Trocar Combined With A One-Directional Valve System In Primary And Secondary Pars Plana Vitrectomy, Ayşe Gül Altintaş, Hasan Basri̇ Ari̇foğlu, Şükrü Gülteki̇n Köklü, Kenan Sönmez Jan 2014

Early Surgical Results Of A 23-Gauge Trocar Combined With A One-Directional Valve System In Primary And Secondary Pars Plana Vitrectomy, Ayşe Gül Altintaş, Hasan Basri̇ Ari̇foğlu, Şükrü Gülteki̇n Köklü, Kenan Sönmez

Turkish Journal of Medical Sciences

To elucidate the early surgical advantages of a 23-gauge trocar combined with a one-directional valve system in transconjunctival pars plana vitrectomies. Materials and methods: Early surgical results of 432 eyes of 432 patients (190 female and 242 male) who underwent 23-gauge (23G) transconjunctival sutureless vitrectomies (TSV) were evaluated. Sixty-three patients out of 432 underwent a second operation, 29 of them underwent silicone oil extraction, and 34 had phacoemulsification surgery with the help of vitreous infusion. If any sign of leakage was observed after the withdrawal of the cannulae, a suture was applied at the conjunctiva-scleral opening site. Results: A total …

Go to article

Calcifying Fibrous Pseudotumor Of Lungs, Serdar Özkan, Funda Demi̇rağ, Erdal Yekeler, Nuretti̇n Karaoğlanoğlu Jan 2014

Calcifying Fibrous Pseudotumor Of Lungs, Serdar Özkan, Funda Demi̇rağ, Erdal Yekeler, Nuretti̇n Karaoğlanoğlu

Turkish Journal of Medical Sciences

Calcified fibrous pseudotumors can generally be detected as solitary masses in various regions of the body, and were first described in 1988. In this case report, we discuss an adult patient whose tumor was localized in the lung, which has not been reported in the literature before.

Go to article

Assessment Of Left Ventricular Function By Strain–Strain Rate Echocardiography In Patients With Celiac Disease, Cenk Sari, Ayli̇n Demi̇rezer Bolat, Fatma Ebru Akin, Ni̇hal Akar Bayram, Sevi̇l Özer Sari, Serdal Baştuğ, Emi̇ne Bi̇len, Hüseyi̇n Ayhan, Telat Keleş, Tahi̇r Durmaz, Osman Ersoy, Engi̇n Bozkurt Jan 2014

Assessment Of Left Ventricular Function By Strain–Strain Rate Echocardiography In Patients With Celiac Disease, Cenk Sari, Ayli̇n Demi̇rezer Bolat, Fatma Ebru Akin, Ni̇hal Akar Bayram, Sevi̇l Özer Sari, Serdal Baştuğ, Emi̇ne Bi̇len, Hüseyi̇n Ayhan, Telat Keleş, Tahi̇r Durmaz, Osman Ersoy, Engi̇n Bozkurt

Turkish Journal of Medical Sciences

Celiac is predominantly a disease of the small intestine characterized by chronic malabsorption in genetically susceptible individuals who ingest grains containing gluten, such as wheat, barley, and rye. In the present study, we evaluate left ventricular function in patients with celiac disease by using strain and strain rate echocardiography imaging. Materials and methods: Twenty celiac patients and 20 healthy controls were included in this study. Left ventricle systolic and diastolic functions were evaluated with standard 2-dimension, M-mode, conventional Doppler echocardiography. Strain and strain rate parameters were obtained for 8 segments of the left ventricle. Results: There were no significant differences …

Go to article

Relationship Of Admission Neutrophil-To-Lymphocyte Ratio With In-Hospital Mortality In Patients With Acute Type-I Aortic Dissection, Gökhan Lafçi, Ömer Faruk Çi̇çek, Haci Alper Uzun, Adnan Yalçinkaya, Adem İlkay Di̇ken, Osman Turak, Kumral Çağli, İrfan Taşoğlu, Hi̇kmet Selçuk Gedi̇k, Kemal Korkmaz, Orhan Eren Günertem, Keri̇m Çağli Jan 2014

Relationship Of Admission Neutrophil-To-Lymphocyte Ratio With In-Hospital Mortality In Patients With Acute Type-I Aortic Dissection, Gökhan Lafçi, Ömer Faruk Çi̇çek, Haci Alper Uzun, Adnan Yalçinkaya, Adem İlkay Di̇ken, Osman Turak, Kumral Çağli, İrfan Taşoğlu, Hi̇kmet Selçuk Gedi̇k, Kemal Korkmaz, Orhan Eren Günertem, Keri̇m Çağli

Turkish Journal of Medical Sciences

Acute aortic dissection is a life-threatening cardiovascular emergency. Neutrophil-to-lymphocyte ratio is proposed as a prognostic marker and found to be related to worse clinical outcomes in various cardiovascular diseases. The aim of the present study was to evaluate the relationship between admission neutrophil-to-lymphocyte ratio and in-hospital mortality in acute type I aortic dissection. Materials and methods: We retrospectively evaluated 123 consecutive patients who had undergone emergent surgery for acute type I aortic dissection. Patients were divided into 2 groups as patients dying in the hospital (Group 1) and those discharged alive (Group 2). All parameters, including neutrophil-to-lymphocyte ratio, were compared …

Go to article

Evaluation Of Hepatocellular Carcinoma With Computed Tomography Perfusion Imaging, Ümmügülsüm Bayraktutan, Abdulmeci̇t Kantarci, Hayri̇ Oğul, Yeşi̇m Kizrak, Ömer Özyi̇ği̇t, Zeyneb Yüceler, Berhan Genç, Bünyami̇ Özoğul Jan 2014

Evaluation Of Hepatocellular Carcinoma With Computed Tomography Perfusion Imaging, Ümmügülsüm Bayraktutan, Abdulmeci̇t Kantarci, Hayri̇ Oğul, Yeşi̇m Kizrak, Ömer Özyi̇ği̇t, Zeyneb Yüceler, Berhan Genç, Bünyami̇ Özoğul

Turkish Journal of Medical Sciences

To evaluate the role of computed tomography (CT) perfusion imaging in patients with hepatocellular carcinoma (HCC). Materials and methods: Seventeen patients (9 men, 8 women) with newly diagnosed HCC, proven by biopsy, were evaluated with 256-slice helical CT. Perfusion parameters of blood flow (BF), blood volume (BV), arterial perfusion (AP), portal perfusion (PP), and hepatic perfusion index (HPI) were calculated in the normal liver parenchyma and HCC samples. Results: A total of 21 histologically proven HCC lesions were evaluated from CT perfusion images. BF, BV, AP, and HPI values were shown to be significantly higher (P < 0.05) in the HCC lesions than in the normal liver parenchyma. Conversely, PP values were found to be significantly lower (P < 0.05) in HCC relative to liver parenchyma. Conclusion: CT perfusion imaging has the ability to evaluate tumor assessment, characterization, and neoangiogenesis in HCC.

Go to article

A Comparison Of The Generation Of Free Radicals In Saliva Of Active And Passive Smokers, Murat Demi̇rtaş, Ünal Şenel, Sevda Yüksel, Mustafa Yüksel Jan 2014

A Comparison Of The Generation Of Free Radicals In Saliva Of Active And Passive Smokers, Murat Demi̇rtaş, Ünal Şenel, Sevda Yüksel, Mustafa Yüksel

Turkish Journal of Medical Sciences

To reveal any correlation between cigarette smoke and malondialdehyde (MDA) values in the saliva fluid of subjects who are active smokers or nonsmoking subjects who are exposed to cigarette smoke in their environments. Materials and methods: Saliva samples were taken from 3 groups: a control group (group 1), a group inhaling smoke passively (group 2), and a test group (group 3) smoking 20 cigarettes per day; each group consisted of 20 members, giving a total sample of 60 people, aged 20 to 45 years. MDA, which is an indicator of lipid peroxidation, was measured via the colorimetric method. Results: Salivary …

Go to article

A Comparison Of The Effects Of Hyperbaric And Isobaric Bupivacaine Spinal Anesthesia On Hemodynamics And Heart Rate Variability, Mehmet Toptaş, Si̇nan Uzman, İlke İşi̇temi̇z, Tümay Uludağ Yanaral, İbrahi̇m Akkoç, Gülşen Bi̇can Jan 2014

A Comparison Of The Effects Of Hyperbaric And Isobaric Bupivacaine Spinal Anesthesia On Hemodynamics And Heart Rate Variability, Mehmet Toptaş, Si̇nan Uzman, İlke İşi̇temi̇z, Tümay Uludağ Yanaral, İbrahi̇m Akkoç, Gülşen Bi̇can

Turkish Journal of Medical Sciences

To compare the effects of hyperbaric and isobaric bupivacaine spinal anesthesia on hemodynamics and heart rate variability (HRV) in nonobstetric surgery. Materials and methods: Sixty patients were randomly allocated to 2 groups. Group I (n = 30) received 15 mg (3 mL) of hyperbaric bupivacaine and Group II (n = 30) received 15 mg (3 mL) of isobaric bupivacaine for spinal anesthesia. Hemodynamic parameters were recorded before and after spinal anesthesia over 30 min. Analyses of HRV were performed on the day of surgery, after volume loading, and 20 min after spinal injection. Low frequency (LF) values, high frequency (HF) …

Go to article

First Prev Next Last