Medicine and Health Sciences Commons^™

Painless Dissecting Aneurysm Of The Thoracic Aorta: Report Of Eight Cases Masquerading As Gross Aortic Insufficiency, Severe Hypertension, Myocardial Infarction And Mediastinal Enlargement., Remigio Garcia, Peter Torbey, Daniel T. Anbe, Ellet H. Drake

Henry Ford Hospital Medical Journal

In a review of 68 patients with dissecting thoracic aorta aneurysm (DTAA), eight patients (11.7%) were found to have painless dissection. Three of the eight patients presented with gross aortic insufficiency (Al). Angiography on a fourth patient, who had severe hypertension, showed Type III DTAA. Three other patients had either dilatation of the ascending aorta or a possible mediastinal mass, according to chest roentgenograms. One patient received treatment for suspected myocardial infarction with cardiogenic shock. A high index of suspicion in patients with unexplained Al, severe hypertension and a mediastinal mass or dilatation of the ascending aorta, coupled with the …

Research Seminar — May 5,1977 — At Henry Ford Hospital

Henry Ford Hospital Medical Journal

No abstract provided.

Apical Closure Induction Using Bone Growth Factors And Mineral Trioxide Aggregate, Kenneth W. Tittle

Loma Linda University Electronic Theses, Dissertations & Projects

This study compared the ability of three different bone growth factor combinations with that of Ca(OH)₂ to stimulate apical closure as well as the effectiveness of Mineral Trioxide Aggregate (MTA) as an apical barrier. Fifty-six roots of second and fourth mandibular premolars of seven six- month old beagle dogs were used. Periradicular lesions were created over a four week period. The canals were cleaned and shaped and filled with Ca(OH)₂ for one week. They were then irrigated and received one of seven different treatments in a balanced design. Growth factors were placed in a carboxymethylcellulose carrier and delivered …

The Philosophy Of Drenching Sheep In Western Australia, G C De Chaneet

Journal of the Department of Agriculture, Western Australia, Series 4

Sheep of all classes are drenched more or less regularly throughout the agricultural areas of Western Australia.

Much of the drench is wasted because it is used in the wrong circumstances. This situation is probably a result of poor understanding of drenching.

This article discusses the philosophy of drenching and attempts to relate this to the epidemiology of parasitism as it is currently understood.

Some Basics Of Marron Production, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

marron are native to the South-West of Western Australia, and are keenly sought by inland fisher-men. However, supplies do not equal the apparent demand.

One solution is to cultivate marron in farm dams, or more intensively as a commercial enterprise.

This article suggests a few guidelines for marron production.

Lumpy Wool May Increase By Dipping : Research Roundup, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

Lumpy wool, or mycotic dermatitis, is an infectious disease on the skin of the sheep caused by the bacterium Dermatophilus conglensis. The organism invades the wool and hair follicles, causing formation of skin lesions producing scabby material which binds the wool fibres into a hard mass.

Research shows that 'dipping' may increase the incidence of lumpy wool with some chemicals a greater risk than others.

Duck Plague Virus An Investigation Of Cytopathic Effects, In-Vitro Host Range, And Inhibition By Phosphonoacetic Acid, Ronald Attanasio

Biological Sciences Theses & Dissertations

Duck plague is a hemorrhagic, necrotic disease found exclusively in the order Anseriformes, family Anatidae (ducks, geese, swans). The etiologic agent has been reported to be a herpes-like virus. The Holland strain of duck plague was found to induce cytopathic effects in cell culture (perinuclear vacuolation followed by lysis). A simple reproducible plaque assay for quantitating the virus was developed. Under conditions of the plaque assay, one-hit kinetics were observed. The host range of duck plague virus in cell culture was found to include the order Galliformes, family Phasianidae (pheasants, quails and partridges). Duck plague virus-induced cell culture cytopathic effects …

Studies On The Grooming Behavior And Morphology Of The Freshwater Prawn, Palaemonetes Kadiakensis, Bruce E. Felgenhauer

Masters Theses

No abstract provided.

Electron Microscopy Of Fibers And Discs Of Hemoglobin S Having Sixfold Symmetry, M. Ohtsuki, S. White, Elmar Zeitler, Tom Wellems, S. Fuller, Martin Zwick, Marvin Makinen, Paul Sigler

Complex Systems Faculty Publications and Presentations

Aggregated forms of deoxyhemoglobin S were examined with a field emission transmission electron microscope. Images of isolated helical fibers were obtained from sickled cell lysates stained directly on the electron microscope grid. Optical and digital analyses of the electron micrographs showed that the fibers are similar to those characterized by J.T. Finch, M. F. Perutz, J. F. Bertles, and J. Dobler [(1973) Proc.NatL Acad. Sci. USA 70, 718-7221 in that they consist of stacked discs each composed of six hemoglobin molecules. The fibers exhibit an outer diameter of 160-170 A and an inner diameter of about 60 A with an …

Inactivation Of Brain Hexokinase By An Adenosine 5'-Triphosphate Analog, Subbarao Bondada, Umakant W. Kenkare

Microbiology, Immunology, and Molecular Genetics Faculty Publications

An analog of ATP, 6-mercapto-9+nribofuranosylpurine 5’-triphosphate (SH-TP), functions as a phosphoryl donor for the reaction catalyzed by hexokinase. Incubation of the enzyme with millimolar concentrations of this reagent led to its rapid inactivation. However, the corresponding monophosphate derivative of this reagent was much less effective. A plot of the initial rate of inactivation versus the concentration of SH-TP exhibited saturation, suggesting the formation of a reversible complex between the enzyme and SH-TP prior to the inactivation reaction. The dissociation constant of this enzyme-inhibitor complex was the same as the K, of this reagent with respect to hexokinase in the phosphoryl …

Reaction Of Brain Hexokinase With Tetranitromethane: Oxidation Of Essential Thiol Groups, Subbarao Bondada, Umakant W. Kenkare

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Treatment of bovine brain mitochondrial hexokinase with a fivefold molar excess of tetranitromethane (TNM) at pH 8.0 results in a complete loss of activity of the enzyme. Spectral measurements and amino acid analysis showed that only cysteinyl residues were modified by TNM under these conditions. The products of the reaction of TNM with the enzyme were cysteic acid and disulfides as found by amino acid analysis of the carboxymethylated hexokinase. Failure of 2-mercaptoethanol to reverse the effect of TNM suggested that the thiol group that is oxidized to cysteic acid is the one essential for enzyme activity. Substrates glucose and …

A Biosystematic Investigation Of Medically Important Yeasts, Nancy Christiansen Ballot

University of the Pacific Theses and Dissertations

The purpose of this study is twofold: (1) conduct an epidemiological survey of yeasts found in clinical material; and (2) suggest an identification scheme that would identify yeasts of medical importance in the shortest possible time.

Recent Research On Cattle Worms : Research Round-Up, F C. Wilkinson, G. De Chaneet

Journal of the Department of Agriculture, Western Australia, Series 4

Summary of research carried out on cattle worms.

Ryegrass Disease Could Spread, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

The disease annual ryegrass toxicity kills sheep and cattle grazing pastures which contain infected annual ryegrass. In Western Australia the first confirmed outbreak was in 1968 in the Gnowangerup area.

The disease has noe spread over a range of 450 kilometres and with a total area of perhaps 100 000 hectares. because annual ryegrass is the major sown pasture grass in W.A. the disease could spread throughout the South-West.

There are some precautions that can be taken.

Molecular Mobilities Of Soluble Components In The Aqueous Phase Of Chromaffin Granules, Edward P. Richards, Robert R. Sharp

Journal Articles

NMR relaxation times have been used to characterize molecular motion and intermolecular complexes in the aqueous phase of bovine chromaffin granules. Partially relaxed '3C and proton spectra have been obtained at 3 and 25°C. T1 measurements of five protonated carbons on epinephrine (C:, Cs, C6, CHOH and NCH3) give a correlation time of 0.15 (10 -9) s at 25°C for the catechol ring and methine carbon, while the effective correlation time for the NCH3 group is somewhat shorter due to its internal degree of rotational freedom. Resonances of protonated carbons on the soluble protein chromogranin give very similar correlation times: …

Analysis Of The Carbon-13 And Proton Nmr Spectra Of Bovine Chromaffin Granules, Edward P. Richards, Robert R. Sharp

Journal Articles

Natural abundance carbon-13 and proton NMR spectra of bovine chromaffin granules have been obtained and analyzed using computer simulation techniques. High resolution spectra show the presence of a fluid aqueous phase containing epinephrine, ATP and a random coil protein. The protein spectrum conrains unusually intense resonances due to glutamic acid and proline and has been simulated satisfactorily using the known amino acid composition of chromogranin A.

The lipid phase of chromaffin granules gives rise to intense, but very broad, resonances in the carbon-13 spectrum. Protons in the lipid phase are also observable as a very rapid component of the proton-free …

The Biochemistry Of Vascular Smooth Muscle In The Spontaneously Hypertensive Rat, John Edward Taylor

University of the Pacific Theses and Dissertations

Cyclic adenosine 3’,5’-monophosphate (cAMP) was first described as the mediator of the glycogenolytic effect of epinephrine and glucagon in the liver almost two decades ago. It has since been found that cAMP may mediate the effects of a number of hormones and neurohormones, and this observation has led to the development of the second messenger hypothesis of hormone action. According to the second messenger theory, the hormone or first messenger brings information to the cell, whereas, the second messenger (cAMP) transfers this information into intracellular events. More recent evidence has described the existence of an additional second messenger, cyclic guanosine …

Use Of Technetium-99 Myocardial Scanning For Identification Of Intraoperative Myocardial Infarctions, Virender D. Parekh, Sidney Goldstein, Donald Magillican, Daniel Marks

Henry Ford Hospital Medical Journal

Technedum 99m stannous pyrophosphate (TcPyP) myocardial scans were obtained in 42 selected nonconsecutive patients within 12 days following open heart operations for both valve replacement (19 patients) and coronary bypass (23 patients) procedures. The scans were correlated with elevation of serum lactic dehydrogenase, glutamic oxalacetic transaminase and the electrocardiograms obtained serially in the postoperative period. TcPyP scan was more specific than enzyme studies and it was more sensitive than the electrocardiogram. All new Q waves were associated with a positive scan but there were five positive scans which were not associated with new Q waves. Myotomy and direct surgical trauma …

Rationale And Results Of Anatomic Repair Of Esophageal Hiatus Hernia, Conrad R. Lam

Henry Ford Hospital Medical Journal

A logical method of repair of esophageal hiatus hernia based on anatomic principles was proposed nearly 25 years ago by the late Phillip Allison. There was general agreement that his operation had advantages, but because of a disappointing number of recurrences and problems with reflux, more complicated operations were devised. Some of these involved plication of the stomach around the lower esophagus (Nissen, Belsey). In a series of 562 operations for hiatus hernia at the Henry Ford Hospital, there has been no significant deviation from the Allison technic. Complicating lower esophageal rings (Schatzki) have been excised. There has been no …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Susceptibility At High Inoculum Of Penicillin-Resistant Staphylococcus Aureus To Six Cephalosporins, Andres Suarez, Ramon Del Busto, Edward L. Quinn, Donald Pohlod

Henry Ford Hospital Medical Journal

Six cephalosporins (currently available for clinical use or undergoing clinical trials) were tested by tube dilution method against high inoculum (10⁷ colony forming units) of 37 strains of penicillin resistant Staphylococcus aureus. 3.1 μg/ml of cephalothin inhibited 100% of strains while higher concentrations of cefoxitin, cephapirin, cefamandole, cephalexin and cephradine were required. The percent of strains with minimal inhibitory concentration higher than 3.1 μg/ml ranged between 10.8% (cefoxitin) and 100% (cephradine). These findings support the observation that cephalothin is less susceptible to inactivation than the other cephalosporins. Although the exact clinical implication of these findings has not been established, …

Front Matter, Vol. 1

Great Basin Naturalist Memoirs

No abstract provided.

End Matter, Vol. 1

Great Basin Naturalist Memoirs

No abstract provided.

Miliary Tuberculosis And Disseminated Intravascular Coagulation: A Case Report, Mohsin Alam, George Bower

Henry Ford Hospital Medical Journal

A case of miliary tuberculosis complicated by respiratory insufficiency and disseminated intravascular coagulation was treated successfully with antituberculosis drugs, ventilatory support, and heparin, packed red cells, platelet transfusions and plasma. Tuberculosis is a rare cause of disseminated intravascular coagulation.

High Dose In-Continuity Irradiation Of Para-Aortic And Pelvic Nodes For Carcinoma Of The Prostate. The First Three-And-One-Half Years, Joel Elliot White, Murray Boles

Henry Ford Hospital Medical Journal

A technique for treating the para-aortic nodes to a high dose of irradiation in continuity with the pelvis has been developed at Henry Ford Hospital and recently described by one of the authors. The "nine-field technique" was initially used in late 1973 to treat two patients with advanced prostatic carcinoma who had grossly involved para-aortic nodes. Since that time, 16 additional patients with carcinoma of the prostate, one patient with carcinoma of the urinary bladder, and one patient with carcinoma of the cervix have been treated by this technique. This paper analyzes sequelae and complications of the technique and mentions …

Osteogenic Sarcoma: Report Of One Hundred And Fifty-Seven Cases, Kent K. Wu, Edwin R. Guise, Harold M. Frost, C. Leslie Mitchell

Henry Ford Hospital Medical Journal

This study presents the clinical features, roentgenographic manifestations, pathological features, abnormal laboratory studies, treatment and prognosis of 157 cases of osteogenic sarcoma. The series is the fifth largest ever reported. The authors favor prompt surgical ablation followed by controlled intensive chemotherapy as a prophylactic or combined chemotherapy and radiation therapy for metastatic osteogenic sarcoma. All case reports but one present rare or unusual situations.

In Memoriam: Robert C. Horn, Jr., M.D., Gerald Fine, John W. Rebuck

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Animal Rights: Nih Cat Sex Study Brings Grief To New York Museum, Nicholas Wade

Popular Press Items

No abstract provided.

Ua77/1 Western Alumnus, Vol. 47, No. 1, Wku Alumni Relations

WKU Administration Documents

Alumni magazine published by WKU. This issue has the following articles:

• Orientation - Advisement - Registration Programs
• Armstrong, Don & Jim Snodgrass. Prize Dairy Herd
• Conway, Sheila. Nursing Goes Baccalaureate
• Snodgrass, Jim. The Hub of the Hill - Goal Post Restaurant
• Oakes, John. Respect Grows for Western Fine Arts Festival
• Krull, Carl. Special Olympics
• Cunningham, Doyle. The Public Service Institute
• Jason Brady's World
• Conway, Sheila. 2076 America: The Next 100 Years
• Allan Ostar Praises Western Spirit
• Students Pick Yell Leaders
• Harvey, Debbie. Christy Vogt Takes Over Associated Student Government
• Award for Public Affairs
• Joe Uveges Publishes Textbook
• James Pearse President-Elect …