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Full-Text Articles in Other Physiology
Impacts Of Dietary Restriction On A Drosophila Model Of Werner Syndrome, Eileen Sember
Impacts Of Dietary Restriction On A Drosophila Model Of Werner Syndrome, Eileen Sember
College of Arts & Sciences Senior Theses
Werner syndrome (WS) is an autosomal recessive disorder that results in premature aging and occurs in 1 in 1,000,0000 to 1 in 10,000,000 people. In humans, WS is the result of mutations that render the WRN gene, that contains a helicase and an exonuclease domain, non-functional. Currently, there is no cure for WS in humans, making dietary and lifestyle interventions attractive for increasing the quality and longevity of lives. Diet restriction (DR) has been shown to extend the lifespan of several model organisms, including Drosophila melanogaster, making it a strong candidate for WS treatment. In this thesis, mutant flies …
Moderate-Load Muscular Endurance Strength Training Did Not Improve Peak Power Or Functional Capacity In Older Men And Women, Simon J. Walker, Greg G. Haff, Keijo K. Häkkinen, Robert U. Newton
Moderate-Load Muscular Endurance Strength Training Did Not Improve Peak Power Or Functional Capacity In Older Men And Women, Simon J. Walker, Greg G. Haff, Keijo K. Häkkinen, Robert U. Newton
Research outputs 2014 to 2021
The present study determined the effects of muscular endurance strength training on maximum strength and power, functional capacity, muscle activation and hypertrophy in older men and women. Eighty-one men and women acted as an intervention group while 22 acted as non-training controls (age range 64-75 y). Intervention training included super-sets (i.e., paired exercises, immediately performing the second exercises following completion of the first) with short rest intervals (30-60 s between sets) at an intensity of 50-60% one-repetition maximum (1-RM) for 15-20 repetitions. Concentric leg press actions measured maximum strength (1-RM) and concentric peak power. Functional capacity was assessed by maximum …