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Articles 1 - 2 of 2
Full-Text Articles in Other Physiology
Understanding The Role Of Toxs As A Bile Sensing Component Of The Toxrs Virulence Regulatory System In Vibrio Spp., Minje Kim
Dartmouth College Ph.D Dissertations
Pathogenic Vibrio bacteria, such as V. cholerae and V. parahaemolyticus, colonize in the human small intestine to cause severe gastrointestinal disease. During the infection, these bacteria encounter bile salts, antimicrobial cholesterol metabolites secreted into the intestine. Pathogenic Vibrio species have evolved to utilize bile salts as signals to regulate virulence. The signaling depends in part on ToxRS, a conserved co-component transmembrane transcription regulator. ToxRS consists of the transcription factor ToxR and its membrane-tethered binding partner ToxS. ToxS is required for ToxR stability and full transcriptional activity. Although bile salts are known to influence ToxRS-dependent virulence gene expression, the molecular …
Effects Of Daylight On College Students’ Physical And Mental Well-Being, Sathya Thenappan
Effects Of Daylight On College Students’ Physical And Mental Well-Being, Sathya Thenappan
Quantitative Social Science Undergraduate Senior Theses
While existing literature predominantly deals with the impact of daylight on adults in general and more specifically at the workplace, less is known about its impact on the college student demographic and daylight exposure levels at college residences. Given its considerable impact on both the physical and mental well-being of individuals, daylight has been used in the treatment of an assortment of diseases from seasonal affective disorder to depression. With college students constituting the majority of today’s people who suffer from mental health issues in society, uncovering the link between daylight exposure and its impact on the physical and mental …