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Endocrinology Commons

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Full-Text Articles in Endocrinology

Flank Gland-Secreted Putative Chemosignals Pertaining To Photoperiod, Endocrine States, And Sociosexual Behavior In Golden Hamsters, Ying-Juan Liu, Da-Wei Wang, Lixing Sun, Jin-Hua Zhang, Jian-Xu Zhang Dec 2010

Flank Gland-Secreted Putative Chemosignals Pertaining To Photoperiod, Endocrine States, And Sociosexual Behavior In Golden Hamsters, Ying-Juan Liu, Da-Wei Wang, Lixing Sun, Jin-Hua Zhang, Jian-Xu Zhang

All Faculty Scholarship for the College of the Sciences

Behavioral studies have shown that flank glands are involved in chemical communication in golden hamsters Mesocricetus auratus but little chemical analysis has been conducted on volatiles arising from these glands. Using gas chromatography- mass spectrometry, we detected compounds from the flank glands of males, only eight of which were also produced in females. Based on these chemical data we performed a number of further experiments. By manipulating light we found that males exposed to short-photoperiods developed smaller flank glands than those exposed to long-photoperiods. Six flank gland volatiles reduced in relative abundance, which possibly coded for reproductive status of males …


A Specific Regulatory Role For Sgtα On The Maturation And Activation Of Steroid Hormone Receptors, Atanu Paul Jan 2010

A Specific Regulatory Role For Sgtα On The Maturation And Activation Of Steroid Hormone Receptors, Atanu Paul

Open Access Theses & Dissertations

Steroid hormone receptors (SHRs) are ligand-dependent transcription factors belonging to the nuclear receptor superfamily. These receptors regulate various physiological functions in higher ordered eukaryotes. In the absence of hormone these receptors form a complex with molecular chaperones such as Hsp90 and Hsp70 and other cochaperones in the cytoplasm. Association with the Hsp90-Hsp70 chaperone machinery leads to the maturation of the Ligand Binding Domain (LBD) of the receptors and enables the receptors to bind hormone with high affinity. Upon binding with a specific hormone the receptors are translocated into the nucleus where they initiate transcription of specific genes. Although the involvement …


Balance Training Reduces Falls Risk In Older Individuals With Type 2 Diabetes, Steven Morrison, Sheri R. Colberg, Mita Mariano, Henri K. Parson, Arthur I. Vinik Jan 2010

Balance Training Reduces Falls Risk In Older Individuals With Type 2 Diabetes, Steven Morrison, Sheri R. Colberg, Mita Mariano, Henri K. Parson, Arthur I. Vinik

Rehabilitation Sciences Faculty Publications

OBJECTIVE - This study assessed the effects of balance/strength training on falls risk and posture in older individuals with type 2 diabetes.

RESEARCH DESIGN AND METHODS - Sixteen individuals with type 2 diabetes and 21 age-matched control subjects (aged 50-75 years) participated. Postural stability and falls risk was assessed before and after a 6-week exercise program.

RESULTS - Diabetic individuals had significantly higher falls risk score compared with control subjects. The diabetic group also exhibited evidence of mild-to-moderate neuropathy, slower reaction times, and increased postural sway. Following exercise, the diabetic group showed significant improvements in leg strength, faster reaction times, …