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Articles 61 - 63 of 63

Full-Text Articles in Endocrinology

The Anorexigenic Fatty Acid Synthase Inhibitor, C75, Is A Nonspecific Neuronal Activator, Kanji A. Takahashi, James L. Smart, Hongyan Liu, Roger D. Cone Jan 2003

The Anorexigenic Fatty Acid Synthase Inhibitor, C75, Is A Nonspecific Neuronal Activator, Kanji A. Takahashi, James L. Smart, Hongyan Liu, Roger D. Cone

Faculty Publications - Department of Biological & Molecular Science

C75, a recently derived compound that potently suppresses feeding and induces weight loss, has been proposed to act mainly by inhibiting fatty acid synthase (FAS) in central neurons that control feeding. For example, normal, fasting- associated, hypothalamic increases in neuropeptide Y (NPY)/Agouti-related protein (AGRP) expression and decreases in proopiomelanocortin (POMC)/cocaine and amphetamine regulated transcript (CART) expression were reported to be blocked by C75. Using loose-patch extracellular recording in acute slices, we tested the effect of C75 on anorexigenic POMC neurons and orexigenic NPY neurons of the hypothalamic arcuate nucleus, which were identified by promoter-driven GFP expression, as well as on …


Comparison Of Lipid And Lipoprotein Levels In Diabetic And Non-Diabetic Juveniles Of Eastern Kentucky, Louise Mccall Isaacs Feb 1981

Comparison Of Lipid And Lipoprotein Levels In Diabetic And Non-Diabetic Juveniles Of Eastern Kentucky, Louise Mccall Isaacs

Morehead State Theses and Dissertations

A thesis presented to the faculty of the School of Science and Mathematics at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science in Biology by Louise McCall Isaacs on February 27, 1981.


An Improved Technique For The Demonstration Of Tissue Lipids, Bryan G. Hoerl Apr 1953

An Improved Technique For The Demonstration Of Tissue Lipids, Bryan G. Hoerl

Master's Theses (1922-2009) Access restricted to Marquette Campus

Progress in science frequently depends upon proper tools to demonstrate, enhance, integrate, substantiate or refute contentions. Among the means that make possible the advance of biological science is histological technique. Improved microscopic procedures result from a constant refining process and the search for new methods. To merit the adjective "improved" a new or refined technique must display a superiority to similarly employed processes. Such superiority might be shown by its speed, economy, practicality, ease or faithfulness of reproduction, or same other attribute. This paper portends to present an improved technique for the demonstration of tissue lipids .