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Full-Text Articles in Physiology

Correlations Between Quantitative Fat–Water Magnetic Resonance Imaging And Computed Tomography In Human Subcutaneous White Adipose Tissue, Aliya Gifford, Ronald C. Walker, Theodore F. Towse, E Brian Welch Dec 2015

Correlations Between Quantitative Fat–Water Magnetic Resonance Imaging And Computed Tomography In Human Subcutaneous White Adipose Tissue, Aliya Gifford, Ronald C. Walker, Theodore F. Towse, E Brian Welch

Peer Reviewed Articles

Beyond estimation of depot volumes, quantitative analysis of adipose tissue properties could improve understanding of how adipose tissue correlates with metabolic risk factors. We investigated whether the fat signal fraction (FSF) derived from quantitative fat–water magnetic resonance imaging (MRI) scans at 3.0 T correlates to CT Hounsfield units (HU) of the same tissue. These measures were acquired in the subcutaneous white adipose tissue (WAT) at the umbilical level of 21 healthy adult subjects. A moderate correlation exists between MRI- and CT-derived WAT values for all subjects, R2=0.54, p<0.0001, with a slope of −2.6, (95% CI [−3.3,−1.8]), indicating that a decrease of 1 HU equals a mean increase of 0.38% FSF. We demonstrate that FSF estimates obtained using quantitative fat–water MRI techniques correlate with CT HU values in subcutaneous WAT, and therefore, MRI-based FSF could be used as an alternative to CT HU for assessing metabolic risk factors.


Workforce Fitness: Description, Contextual Issues, And Implications For Public Health, Nicolaas P. Pronk Sep 2015

Workforce Fitness: Description, Contextual Issues, And Implications For Public Health, Nicolaas P. Pronk

Frontiers in Public Health Services and Systems Research

Workforce fitness matters for the prevention of premature death, chronic diseases, productivity loss, excess medical care costs, loss of income or family earnings, and other social and economic concerns. Yet fitness levels appear to be relatively low and declining. Over the past half century obesity has doubled, physical activity levels are below par, and cardiorespiratory fitness often does not meet minimally acceptable job standards. During this time, daily occupational energy expenditure has decreased by more than 100 calories. It is recommended for employers to consider best practices and design workplace wellness programs accordingly. Regulations that protect and promote worker health, …


Exercise Ameliorates High Fat Diet Induced Cardiac Dysfunction By Increasing Interleukin 10., Varun Kesherwani, Vishalakshi Chavali, Bryan T. Hackfort, Suresh C. Tyagi, Paras K. Mishra Apr 2015

Exercise Ameliorates High Fat Diet Induced Cardiac Dysfunction By Increasing Interleukin 10., Varun Kesherwani, Vishalakshi Chavali, Bryan T. Hackfort, Suresh C. Tyagi, Paras K. Mishra

Journal Articles: Cellular & Integrative Physiology

Increasing evidence suggests that a sedentary lifestyle and a high fat diet (HFD) leads to cardiomyopathy. Moderate exercise ameliorates cardiac dysfunction, however underlying molecular mechanisms are poorly understood. Increased inflammation due to induction of pro-inflammatory cytokine such as tumor necrosis factor-alpha (TNF-α) and attenuation of anti-inflammatory cytokine such as interleukin 10 (IL-10) contributes to cardiac dysfunction in obese and diabetics. We hypothesized that exercise training ameliorates HFD- induced cardiac dysfunction by mitigating obesity and inflammation through upregulation of IL-10 and downregulation of TNF-α. To test this hypothesis, 8 week old, female C57BL/6J mice were fed with HFD and exercised (swimming …


Community Based Nutritition Education: A Model For Raising Awareness Of Childhood Obesity, Selina Ahmed Mar 2015

Community Based Nutritition Education: A Model For Raising Awareness Of Childhood Obesity, Selina Ahmed

Selina M Ahmed PhD

Background: Since 2003, Texas Southern University has coordinated conferences to educate Houston’s Third Ward community about strategies to combat childhood obesity. Presenters included faculty and students as speakers and activity coordinators. Participants indicated that these conferences are helpful in increasing awareness of health problems and the availability of community health resources. Purpose: To address the high rate of childhood obesity in Houston’s Third Ward and its costs in terms of health and long-term productivity on that community, faculty at Texas Southern University (TSU) coordinated annual conferences to educate community members about strategies to combat childhood obesity. Methods: Seven conferences intended …


Effects Of Obesity On Stability Control Among Young Adults In Responding To A Simulated Slip Induced In Gait, Jaeeun Kim Feb 2015

Effects Of Obesity On Stability Control Among Young Adults In Responding To A Simulated Slip Induced In Gait, Jaeeun Kim

International Journal of Exercise Science: Conference Proceedings

Falls among older adults present a significant medical, societal, and economic challenge affecting not only the frail or impaired, but the active and vigorous. Falls initiated by slip account for about 25% of all falls among older people. Obesity has been regarded as a significant health problem. It has been reported that obesity causes muscle weakness, abnormal body mass distribution, and postural instability. Dynamic gait stability has been identified as a key factor leading to falls during slip in gait among both young and old adults. Despite the fact that obese individuals suffer higher risk of falls compared to non-obese …


Restraint Stress Alters Pro-Inflammatory Cytokine Expression And Increases Superoxide Dismutase In The Rat Hypothalamus And Hippocampus, Kristina Isabel Barron Jan 2015

Restraint Stress Alters Pro-Inflammatory Cytokine Expression And Increases Superoxide Dismutase In The Rat Hypothalamus And Hippocampus, Kristina Isabel Barron

Open Access Theses & Dissertations

The impact of restraint stress on changes in cytokine expression and oxidative stress markers in hippocampal (Hipp) and hypothalamic (Hyp) regions of the brain, were assessed in a rat model. In addition, immune and inflammatory variables were assessed in peripheral blood. Male Wistar rats were acutely (30 min) or repeatedly (30 min/d for 14 consecutive days) exposed to a restraint stress, or maintained as non-stressed controls. At the time of sacrifice, whole blood and brain tissues enriched in Hyp or Hipp regions were collected; blood was collected with EDTA as an anticoagulant and centrifuged to yield plasma. All tissue samples …