Physiology Commons^™

Effective Water Competence Training For School-Aged Children: Teaching Strategies For Skills, Knowledge, And Attitudes, Kristine De Martelaer Ph.D., E. D'Hondt, J. Van Driel, F. Bardid, Joost J.L.M. Bierens Md, Ph.D., Professor

International Journal of Aquatic Research and Education

No abstract provided.

Efforts In The State Of Texas To Reduce Drownings And Submersion Injuries, Kim Tyson B.Sc., M.Sc.

International Journal of Aquatic Research and Education

No abstract provided.

Guiding Principles: Applying Water Competence To Drowning Prevention, Stephen J. Langendorfer Ph.D., Kevin Moran Ph.D., Robert Keig Stallman Ph.D.

International Journal of Aquatic Research and Education

No abstract provided.

How The Human Immune System Reacts To Stress Such As Drowning, Luke O'Neill Ph.D., Frs

International Journal of Aquatic Research and Education

No abstract provided.

Front Cover

International Journal of Aquatic Research and Education

No abstract provided.

Investigating Drownings In Australia, Paul Reynolds Senior Constable

International Journal of Aquatic Research and Education

No abstract provided.

Understanding The Role Of The Personal Floatation Device: Workshop, Patrick Buck Ph.D., Remt

International Journal of Aquatic Research and Education

No abstract provided.

The Lifesaving Foundation Collection

International Journal of Aquatic Research and Education

No abstract provided.

In Extreme Open Water Swims: Why Understanding The Challenge Is As Important As Training For The Distance, Nuala Moore

International Journal of Aquatic Research and Education

No abstract provided.

Rnli: ‘Respect The Water’ Campaign – Putting Prevention First, Ross Macleod Ba

International Journal of Aquatic Research and Education

No abstract provided.

Am I Schizophrenic? Surviving Life And Death Situations, John Connolly B.Ed., Ma

International Journal of Aquatic Research and Education

No abstract provided.

Investigating Drownings In Ireland, David Hearne Garda

International Journal of Aquatic Research and Education

No abstract provided.

How To Help People Float, Andrea Andrews B.Sc., M.Sc.

International Journal of Aquatic Research and Education

No abstract provided.

Bringing Home The Bodies Of Those Who Drown Abroad: The Kevin Bell Repatriation Trust, Colin Bell

International Journal of Aquatic Research and Education

No abstract provided.

Rlla: Surviving As A Small National Lifesaving Organisation - Progress In Lesotho: From 2004 To 2018, Colin Macdonald Obe, Ba, Ma

International Journal of Aquatic Research and Education

No abstract provided.

The Ireland Medal Recipients 2003-2017

International Journal of Aquatic Research and Education

No abstract provided.

The Lifesaving Foundation Library Collection, Kieran Cronin Ba, Mals

International Journal of Aquatic Research and Education

No abstract provided.

Postpartum Depression: Prevention And Multimodal Therapy, Anca Daniela Stanescu, Denisa Oana Balalau, Liana Ples, Stana Paunica, Cristian Balalau

Journal of Mind and Medical Sciences

A woman goes through many biological (hormonal, physical), psychological (emotional), and socio-cultural changes during pregnancy. Furthermore, changes also occur in the mother's familial and interpersonal world after childbirth. While some mothers have positive emotions at birth, such as joy and pleasure, others complain of negative experiences varying from sadness and depression to psychosis. Thus, the risk of depression is higher for women during the postpartum period, having a tendency to decrease in most cases over the first 2 weeks after delivery. Unfortunately, this favorable evolution does not happen in about 1 in 4-7 women, who develops postpartum depression. Postpartum depression …

Tutorial For Using Sliceomatic To Calculate Thigh Area And Composition From Computed Tomography Images From Older Adults, Richard A. Dennis, Douglas E. Long, Reid D. Landes, Kalpana P. Padala, Prasad R. Padala, Kimberly K. Garner, James N. Wise, Charlotte A. Peterson, Dennis H. Sullivan

Center for Muscle Biology Faculty Publications

Objective

Area of muscle, fat, and bone is often measured in thigh CT scans when tissue composition is a key outcome. SliceOmatic software is commonly referenced for such analysis but published methods may be insufficient for new users. Thus, a quick start guide to calculating thigh composition using SliceOmatic has been developed.

Methods

CT images of the thigh were collected from older (69 ± 4 yrs, N = 24) adults before and after 12-weeks of resistance training. SliceOmatic was used to segment images into seven density regions encompassing fat, muscle, and bone from -190 to +2000 Hounsfield Units [HU]. The …

Editorial: Ion Channel Trafficking And Cardiac Arrhythmias, Marcel A. G. Van Der Heyden, Brian P. Delisle, Hugues Abriel

Physiology Faculty Publications

No abstract provided.

Improving Health Through Diet And Exercise In Children, Elaine Rush, Tara Coppinger

Publications

We know that nutritious foods and quality physical activity are two of the fundamental needs for normal growth and development of children. Food based dietary guidelines and physical activity recommendations have universal evidence base but the teaching of fundamental movement skills is limited without support. Given the importance of prevention of childhood obesity the distal drivers also need to be examined including poverty. Interventions trialled in carefully controlled conditions while shown to have efficacy are not effective in the real world. There is a need for more research and rigorous evaluation of interventions in combinations of settings and with innovative …

Effect Of Exercise Volume On Hdl-Cholesterol: A 7-Year Case Study, David P. Swain

Human Movement Studies & Special Education Faculty Publications

Introduction: While exercise is known to increase HDL-cholesterol, it is not known if larger exercise volumes produce larger increases in HDL. However, the range of exercise volumes used in most training studies is limited. This report presents a case study of a middle-aged male who engaged in large variations of exercise volume over 7 years while frequently measuring HDL. The purpose was to determine if large increases in exercise volume were associated with larger increases in HDL than previously reported.

Methods: The subject maintained detailed logs of his main form of exercise, bicycling. These logs were analyzed to determine the …

Reestablishing A Culture Of Water Competency At An Hbcu, Knolan C. Rawlins

International Journal of Aquatic Research and Education

African American children ages 5 – 19 years drown in swimming pools at rates of 5.5 times higher than those of whites (Gilchrist & Parker, 2014). Literature suggested culture is the culprit for this disparity. A fear of water dates to slavery (Pitts, 2007). After slavery was abolished, the memory of drowning remained part of the African American culture. In the twentieth century, the popularity of swimming grew with the increase in public pools. The era of the Jim Crow laws kept African Americans out of public pools (Pitts, 2007). Although the political landscape has shifted since the Jim Crow …

Fars2 Mutations Presenting With Pure Spastic Paraplegia And Lesions Of The Dentate Nuclei, Supreet K. Sahai, Rebecca E. Steiner, Margaret G. Au, John M. Graham, Norikio Salamon, Michael Ibba, Tyler M. Pierson

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Mutations in FARS2, the gene encoding the mitochondrial phenylalanine‐tRNA synthetase (mtPheRS), have been linked to a range of phenotypes including epileptic encephalopathy, developmental delay, and motor dysfunction. We report a 9‐year‐old boy with novel compound heterozygous variants of FARS2, presenting with a pure spastic paraplegia syndrome associated with bilateral signal abnormalities in the dentate nuclei. Exome sequencing identified a paternal nonsense variant (Q216X) lacking the catalytic core and anticodon‐binding regions, and a maternal missense variant (P136H) possessing partial enzymatic activity. This case confirms and expands the phenotype related to FARS mutations with regards to clinical presentation and neuroimaging findings.

Targeting Neuropeptides To Bone Fractures For Accelerated Healing, Nicholas A. Young, Jeffery J. Nielsen, Philip S. Low

The Summer Undergraduate Research Fellowship (SURF) Symposium

In patients over the age of 65 especially, bone fractures represent a significant disease burden. Non-invasive drug therapies are not available for bone fractures which represents a problem for this population. Vasoactive intestinal peptide (VIP) and Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), two neuromodulator peptides in the glucagon superfamily, have demonstrated positive regulation of osteoblast proliferation and activity. Using acidic oligopeptides, we have developed ligands that target to and accumulate at fracture sites. These targeting ligands can be synthesized in sequence with bone anabolic peptides to minimize off target effects and increase potency at the fracture site to create safer and …

The Role Of Developmental Timing Regulators In Progenitor Proliferation And Cell Fate Specification During Mammalian Neurogenesis, Jennifer S. Romer-Seibert

Graduate School of Biomedical Sciences Theses and Dissertations

Developmental timing is a key aspect of tissue and organ formation in which distinct cell types are generated through a series of steps from common progenitors. These progenitors undergo specific changes in gene expression that signifies both a distinct progenitor type and developmental time point that thereby specifies a particular cell fate at that stage of development. The nervous system is an important setting for understanding developmental timing because different cell types are produced in a certain order and the switch from stem cells to progenitors requires precise timing and regulation. Notable examples of such regulatory molecules include the RNA-binding …

Insight Into Translational Activation In Yeast Mitochondria, Julia Lynn Jones

Graduate School of Biomedical Sciences Theses and Dissertations

Mitochondrial function depends on over a thousand proteins, of which the majority are nuclear DNA-encoded and approximately one percent are mitochondrial DNA-encoded. The mitochondrial DNA of Saccharomyces cerevisiae contains eight protein-encoding genes, seven of which are required for proper function of the respiratory complexes and one encodes a ribosomal protein. The bigenomic nature of the oxidative phosphorylation complexes requires coordinated expression and regulation from both the nuclear and the mitochondrial genomes. It is currently unclear how this regulatory network operates. However, it is thought that nuclear genome-encoded messengers localized to the mitochondria aid in this coordination.

A family of proteins …

Overexpression Of Cyb5r3 And Nqo1, Two Nad+-Producing Enzymes, Mimics Aspects Of Caloric Restriction, Alberto Diaz-Ruiz, Michael Lanasa, Joseph Garcia, Hector Mora, Frances Fan, Alejandro Martin-Montalvo, Andrea Di Francesco, Miguel Calvo-Rubio, Andrea Salvador-Pascual, Miguel A. Aon, Kenneth W. Fishbein, Kevin J. Pearson, Jose Manuel Villalba, Placido Navas, Michel Bernier, Rafael De Cabo

Pharmacology and Nutritional Sciences Faculty Publications

Calorie restriction (CR) is one of the most robust means to improve health and survival in model organisms. CR imposes a metabolic program that leads to increased stress resistance and delayed onset of chronic diseases, including cancer. In rodents, CR induces the upregulation of two NADH‐dehydrogenases, namely NAD(P)H:quinone oxidoreductase 1 (Nqo1) and cytochrome b₅ reductase 3 (Cyb5r3), which provide electrons for energy metabolism. It has been proposed that this upregulation may be responsible for some of the beneficial effects of CR, and defects in their activity are linked to aging and several age‐associated diseases. However, …

The Role Of Perivascular Fibrosis In Post-Stroke Glymphatic Impairment And Cerebral Amyloid Angiopathy, Matthew D. Howe

Dissertations and Theses (Open Access)

In healthy brain tissue, toxic amyloid-β (Aβ) proteins are transported by the pulsatile flow of cerebrospinal fluid (CSF) along perivascular drainage pathways. Ischemic stroke may disrupt this process, leading to a perivascular build-up of Aβ, termed cerebral amyloid angiopathy (CAA). I hypothesize that an abnormal pattern of extracellular matrix deposition within the vascular basement membrane, termed fibrosis, impairs Aβ drainage from the aged brain after stroke. I further hypothesize that inhibition of astrocytic transforming growth factor-β (TGF-β) signaling can reverse these phenotypes. Finally, I also hypothesize that serum biomarkers of perivascular fibrosis can be used to diagnose CAA following intracerebral …

Association Between Bone-Specific Physical Activity Scores And Pqct-Derived Measures Of Bone Strength And Geometry In Healthy Young And Middle-Aged Premenopausal Women., Sojung Kim, Breanne S Baker, Pragya Sharma-Ghimire, Debra A Bemben, Michael G Bemben

College of Science & Mathematics Departmental Research

The aim of this study was to determine if bone-specific physical activity questionnaire (BPAQ) scores were positively related to bone health in healthy young and middle-aged premenopausal women. The total BPAQ was a stronger predictor of bone strength and bone mineral density of hip in young women as compared to middle-aged premenopausal women.

PURPOSE: The purpose of this study was to determine whether the BPAQ scores were predictive indices of volumetric BMD (vBMD), bone strength, and bone geometry in young and middle-aged premenopausal women.

METHODS: Healthy young (n = 60) and middle-aged premenopausal women (n = 54) between the ages …