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Articles 541 - 570 of 1530
Full-Text Articles in Pharmacology
Biopharmaceuticals: An Overview, Bhupinder Singh Sekhon
Biopharmaceuticals: An Overview, Bhupinder Singh Sekhon
The Thai Journal of Pharmaceutical Sciences
Biopharmaceuticals drugs structurally mimics compounds found within the body and are produced using biotechnologies. These have the potential to cure diseases rather than merely treat symptoms, and have fewer side effects because of their specificity, fo...
Conjugation Of Some Nsaids With 5-Phenyl-2-Aminothiazole For Reduced Ulcerogenicity, Abhilasha Verma, Nirupam Das, Meenakshi Dhanawat, Sushant K. Shrivastava
Conjugation Of Some Nsaids With 5-Phenyl-2-Aminothiazole For Reduced Ulcerogenicity, Abhilasha Verma, Nirupam Das, Meenakshi Dhanawat, Sushant K. Shrivastava
The Thai Journal of Pharmaceutical Sciences
Analgesic drugs containing free acidic group were reacted with N, N' carbonyldiimidazole to prepare the acylimidazole derivatives. They were further reacted with 5-phenyl-2-amino thiazole nucleus to obtain the corresponding amides. All the compounds were...
Anticonvulsant Activity Of Methanolic Extract Of Clerodendron Infortunatum Linn, In Swiss Albino Mice, Sudipta Das, Pallab K., Goutam Pramanik, Siva P. Panda, Samit Bera
Anticonvulsant Activity Of Methanolic Extract Of Clerodendron Infortunatum Linn, In Swiss Albino Mice, Sudipta Das, Pallab K., Goutam Pramanik, Siva P. Panda, Samit Bera
The Thai Journal of Pharmaceutical Sciences
The present study was designed to investigate the anticonvulsant and sleep potentiation effect of methanolic extract of C lerodendron info rtun atum Linn. (MECI) leaves in Swiss albino mice. The anticonvulsant effect of the MECI (250, 500 mg/kg body weig...
Use Of Charge Transfer Complexation Reaction For The Spectrophotometric Determination Of Bupropion In Pharmaceuticals And Spiked Human Urine, Kanakapura Basavaiah, Sameer A. M.
Use Of Charge Transfer Complexation Reaction For The Spectrophotometric Determination Of Bupropion In Pharmaceuticals And Spiked Human Urine, Kanakapura Basavaiah, Sameer A. M.
The Thai Journal of Pharmaceutical Sciences
This is the first report on use of two visible spectrophotometric methods for the determination of bupropion hydrochloride (BUPH) in pharmaceuticals and spiked human urine. Bupropion is a second-generation antidepressant agent which is also used in the m...
Inhibitory Effect Of 2,5-Bis(4-Hydroxy-3-Methoxybenzylidene) Cyclopentanone On Mast Cell Histamine Mediated-Rat Paw Edema, Agung Endro Nugroho, Sardjiman, Kazutaka Maeyama
Inhibitory Effect Of 2,5-Bis(4-Hydroxy-3-Methoxybenzylidene) Cyclopentanone On Mast Cell Histamine Mediated-Rat Paw Edema, Agung Endro Nugroho, Sardjiman, Kazutaka Maeyama
The Thai Journal of Pharmaceutical Sciences
2,5-Bis(4-hydroxy-3-methoxybenzylidene)cyclopentanone, known as pentagamavunon-0 (PGV-0), is a benzylidene cyclopentanone analog of curcumin. This compound posses stronger pharmacological activities such as anti-inflammatory, antioxidative and antibacter...
Sensitive Ultraviolet Spectrophotometric Determination Of Quetiapine Fumarate In Pharmaceuticals, K. Basavaiah, N. Rajendraprasad, P.J. Ramesh, K.B. Vinay
Sensitive Ultraviolet Spectrophotometric Determination Of Quetiapine Fumarate In Pharmaceuticals, K. Basavaiah, N. Rajendraprasad, P.J. Ramesh, K.B. Vinay
The Thai Journal of Pharmaceutical Sciences
Quetiapine fumarate (QTF) is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives indicated for the treatment of schizophrenia. It is a selective monoaminergic antagonist with high affinity for the serotonin type 2 (5HT2), an...
Improvement In The Dissolution Of Poorly Water Soluble Drug Using Media Milling Technique, Dhaval J. Patel, Jayvadan K., Vikram M. Pandya
Improvement In The Dissolution Of Poorly Water Soluble Drug Using Media Milling Technique, Dhaval J. Patel, Jayvadan K., Vikram M. Pandya
The Thai Journal of Pharmaceutical Sciences
The rate of dissolution is rapidly becoming the leading hurdle in formulation development of poorly water-soluble drugs. In the present work, media milling was employed to formulate nanoparticles of a poorly water-soluble anti-ulcer drug, famotidine (FAM...
Studies On Formulation Development Of Apoorly Water - Soluble Drug Through Solid Dispersion Technique, Sunita Dahiya
Studies On Formulation Development Of Apoorly Water - Soluble Drug Through Solid Dispersion Technique, Sunita Dahiya
The Thai Journal of Pharmaceutical Sciences
An attempt has been made to enhance dissolution of aceclofenac (AC) by solid dispersion technique using water soluble carriers PEG 6000 and β-cyclodextrin (β-CD). Solid dispersions of AC with PEG 6000 were prepared by melting solvent method and with β...
Author Index, Keyword Index, N/A
Author Index, Keyword Index, N/A
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Micelle Enhanced Spectrofluorimetric Method For The Determination Of Ofloxacin And Lomefloxacin In Human Urine And Serum, Kuldeep Kaur, Baldev Singh, Ashok Kumar Malik
Micelle Enhanced Spectrofluorimetric Method For The Determination Of Ofloxacin And Lomefloxacin In Human Urine And Serum, Kuldeep Kaur, Baldev Singh, Ashok Kumar Malik
The Thai Journal of Pharmaceutical Sciences
A spectrofluorimetric method for the determination of two fluoroquinolone drugs, ofloxacin and lomefloxacin in biological fluids has been developed. The method is based on native fluorescence of these drugs in micellar medium of sodium dodecyl sulfate (S...
Simultaneous Spectrophotometric Determination Of Iron (Ii) And Copper (Ii) In Tablets By Chemometric Methods, Melisew Tadele Alula, Abdel-Maaboud I., Adnan A. Bekhit
Simultaneous Spectrophotometric Determination Of Iron (Ii) And Copper (Ii) In Tablets By Chemometric Methods, Melisew Tadele Alula, Abdel-Maaboud I., Adnan A. Bekhit
The Thai Journal of Pharmaceutical Sciences
The significant spectral overlap (Di)0.5 = 0.5667 which is about 75.3% overlapping of the UV/Visible absorption spectra of iron (II) and copper (II) complexes necessitates chemometric assisted methods for simultaneous analysis of these ions in the pharma...
Antitumour Activities Of Some Schiff Bases Derived From Benzoin, Salicylaldéhyde, Amino Phenol And 2,4 Dinitrophenyl Hydrazine, M. Jesmin, M.M. Ali, J.A. Khanam
Antitumour Activities Of Some Schiff Bases Derived From Benzoin, Salicylaldéhyde, Amino Phenol And 2,4 Dinitrophenyl Hydrazine, M. Jesmin, M.M. Ali, J.A. Khanam
The Thai Journal of Pharmaceutical Sciences
Three schiff bases PDH [N-(1-phenyl-2-hydroxy-2phenyl ethyledine)-2', 4' dinitrophenyl hydrazine], PHP [N-(1 -phenyl, 2-hydroxy-2-phenyl ethylidine)-2' hydroxy phenyl imine] and HHP [N-(2-hydroxy benzylidine)-2' hydroxy phenyl imine] have been studied ag...
Antioxidant And Neuroprotective Effects Of Standardized Extracts Of Mangifera Indica Leaf, Kanistha Kawpoomhae, Monrudee Sukma, Tanasait Ngawhirunpat, Praneet Opanasopit, Areerut Sripattanaporn
Antioxidant And Neuroprotective Effects Of Standardized Extracts Of Mangifera Indica Leaf, Kanistha Kawpoomhae, Monrudee Sukma, Tanasait Ngawhirunpat, Praneet Opanasopit, Areerut Sripattanaporn
The Thai Journal of Pharmaceutical Sciences
Standardized methanol and aqueous extracts of Mangifera indica L. (mango) leaf were analyzed for antioxidant and neuroprotective activities. Antioxidant activities were evaluated by 2, 2-azinobis 3-ethylbenzothiazoline 6-sulfonate (ABTS), 1,1-diphenyl-2-...
Comparative Study Of Extraction, Purification And Estimation Of Bromelain From Stem And Fruit Of Pineapple Plant, S. S. Gautam, S. K., V. Dash, Amit K. Goyal, G. Rath
Comparative Study Of Extraction, Purification And Estimation Of Bromelain From Stem And Fruit Of Pineapple Plant, S. S. Gautam, S. K., V. Dash, Amit K. Goyal, G. Rath
The Thai Journal of Pharmaceutical Sciences
Bromelain is a major proteinase, isolated from pineapple (Ananas comosus). In the plant, bromelain is accumulated in the entire plant to different extent and properties depending on its source. The objective of present study was to compare the amount and...
Patients’ Opinion And Practice Toward Unused Medication Disposal In Malaysia : A Qualitative Study, Redhwan Ahmed Al-Naggar, Adel Alareefi
Patients’ Opinion And Practice Toward Unused Medication Disposal In Malaysia : A Qualitative Study, Redhwan Ahmed Al-Naggar, Adel Alareefi
The Thai Journal of Pharmaceutical Sciences
This study was conducted to explore the opinion and practice toward disposal of unused medication among patients in Malaysia. An in-depth interview conducted during the period from December 2009 until February 2010. A total of 28 patients participated in...
Biomaterial As Nanobiopharmaceuticals, Murugan Veerapandian, Mohana Marimuthu, Kyu-Sik Yun, Sanghyo Kim
Biomaterial As Nanobiopharmaceuticals, Murugan Veerapandian, Mohana Marimuthu, Kyu-Sik Yun, Sanghyo Kim
The Thai Journal of Pharmaceutical Sciences
The development of wide spectrum of drug delivery systems is fundamental importance to change the establishment of disease diagnosis, treatment and prevention. The fusion technologies of material science and nanomedicine have emerged as a new alternative...
Evaluation Of Antityrosinase And Antioxidant Activities Of Raphanus Sativus Root: Comparison Between Freeze-Dried Juice And Methanolic Extract, Rattanamanee Jakmatakul, Rutt Suttisri, Parkpoom Tengamnuay
Evaluation Of Antityrosinase And Antioxidant Activities Of Raphanus Sativus Root: Comparison Between Freeze-Dried Juice And Methanolic Extract, Rattanamanee Jakmatakul, Rutt Suttisri, Parkpoom Tengamnuay
The Thai Journal of Pharmaceutical Sciences
Two types of extracts (freeze-dried juice and methanolic extract) from the root of Thai radish (Raphanus sativus L.) were evaluated for antityrosinase and antioxidant activities to determine their potential as a skin-whitening and anti-aging agent in cos...
Downstreaming And Purification Of Lovastatin From Monascus Purpureus Culture, Ajaz Ahmad, Bibhu Prasad, Shamshir Khan, Mohd. All, Saleem Javed
Downstreaming And Purification Of Lovastatin From Monascus Purpureus Culture, Ajaz Ahmad, Bibhu Prasad, Shamshir Khan, Mohd. All, Saleem Javed
The Thai Journal of Pharmaceutical Sciences
Lovastatin, an inhibitor of HMG-CoA reductase was produced using M onascus purpureus strain. A new extraction procedure was applied which yielded 737mg of lovastatin per liter of synthetic medium from in to to culture. Purification of extracted lovastati...
Pharmaceutically Equivalent Parenteral Depot Suspension Of Methyl Prednisolone Acetate, A. Alam, J. Ali, A. Ahuja, S. Baboota, S.K. Gidwani, Y.S. Bhide, F. Shakeel
Pharmaceutically Equivalent Parenteral Depot Suspension Of Methyl Prednisolone Acetate, A. Alam, J. Ali, A. Ahuja, S. Baboota, S.K. Gidwani, Y.S. Bhide, F. Shakeel
The Thai Journal of Pharmaceutical Sciences
The aim of the present study was to formulate and evaluate pharmaceutically equivalent injectable aqueous suspension for parenteral depot of methyl prednisolone acetate (MPA). Various aqueous suspensions were prepared by rapid stirring and colloid millin...
Glutathione S-Transferase Polymorphisms And Risk Of Bladder Cancer In Thais, Kannika Pradubkaew, Pornpen Pramyothin, Chanin Limwongse, Payiarat Suwannasri, Anunchai Assawamakin
Glutathione S-Transferase Polymorphisms And Risk Of Bladder Cancer In Thais, Kannika Pradubkaew, Pornpen Pramyothin, Chanin Limwongse, Payiarat Suwannasri, Anunchai Assawamakin
The Thai Journal of Pharmaceutical Sciences
In this study, we determine the association of glutathione S-transferase Mu-1 gene (G STM1), glutathione S-transferase Pi-1 gene (GSTP1) and glutathione S-transferase Theta-1 gene (GSTT1) polymorphisms and the risk of bladder cancer in Thais. One hundred...
Acute Oral Toxicity Studies Of Antipsoriatic Herbal Mixture Comprising Of Aqueous Extracts Of Calendula Officinalis, Momordica Charantia, Cassia Tora And Azadirachta Indica Seed Oil, Roopashree Ts, Raman Dang, Shobha Rani Rh, Narendra C
Acute Oral Toxicity Studies Of Antipsoriatic Herbal Mixture Comprising Of Aqueous Extracts Of Calendula Officinalis, Momordica Charantia, Cassia Tora And Azadirachta Indica Seed Oil, Roopashree Ts, Raman Dang, Shobha Rani Rh, Narendra C
The Thai Journal of Pharmaceutical Sciences
Aqueous extracts of Calendula officinalis, Momordica charantia, Cassia tora and A zadirachta indica seed oil have been used individually for treating skin diseases such as psoriasis in traditional system of medicine. Though the individual herbal extracts...
Effects Of The Standard Extract Of Centella Asiatica (Eca233) On Rat Hepatic Cytochrome P450, Kornphimol Kulthong, Mayuree H., Nuansri Niwattisaiwong, Khemchat Apipalakul, Songpol Chevapat, Somsong Lawanprasert
Effects Of The Standard Extract Of Centella Asiatica (Eca233) On Rat Hepatic Cytochrome P450, Kornphimol Kulthong, Mayuree H., Nuansri Niwattisaiwong, Khemchat Apipalakul, Songpol Chevapat, Somsong Lawanprasert
The Thai Journal of Pharmaceutical Sciences
Centella asiatica (L.) Urban (Umbelliferae) has been used traditionally in various diseases. The aim of this study was to examine subchronic effects of the standard extract of c. asiatica (ECa233) on hepatic xenobiotic/drug metabolizing enzymes, particul...
Floating Matrix Tablets Of Domperidone: Formulation And Optimization Using Simplex Lattice Design, Shailesh T. Prajapati, Laxmanbhai D., Chhaganbhai N. Patel
Floating Matrix Tablets Of Domperidone: Formulation And Optimization Using Simplex Lattice Design, Shailesh T. Prajapati, Laxmanbhai D., Chhaganbhai N. Patel
The Thai Journal of Pharmaceutical Sciences
One method of achieving sustained drug release is by the use of hydrophilic polymeric excipients directly compressed with active ingredients into tablets. Hydrophilic polymers swell in the presence of water to form hydrogel structures from which drugs ar...
Screening Of Antifungal Activities Of Barks Of Cinnamomum Species, M. Maridass
Screening Of Antifungal Activities Of Barks Of Cinnamomum Species, M. Maridass
The Thai Journal of Pharmaceutical Sciences
Antifungal activity of the essential oil from Cinnamomum species have been evaluated in this present study. Essential oils were collected through hydro distillation for 4 h from barks of C. sulphuratum, C. walaiwarense, C. travancoricum and C. malabatrum...
Effects Of Longan Seed Extract On Scopolamine-Induced Learning And Memory Deficit In Mice, Nattanan Losuwannarak, Cholatit Pasadhika, Mayuree H. Tantisira, Boonyong Tantisira
Effects Of Longan Seed Extract On Scopolamine-Induced Learning And Memory Deficit In Mice, Nattanan Losuwannarak, Cholatit Pasadhika, Mayuree H. Tantisira, Boonyong Tantisira
The Thai Journal of Pharmaceutical Sciences
Longan (Euphoria longana) seed is a traditional Chinese medicinal plant which has been claimed to have positive effect on deficit in learning and memory. In this study, the effects of crude ethanolic extracts of longan seed on learning and memory impairm...
Simultaneous Spectrophotometric Determination Of Carbidopa And Levodopa By Partial Least Squares Regression, Principal Component Regression And Least Squares Support Vector Machine Methods, Kuldeep Kaur, Ashok Kumar, Baldev Singh, M. Godarzi
Simultaneous Spectrophotometric Determination Of Carbidopa And Levodopa By Partial Least Squares Regression, Principal Component Regression And Least Squares Support Vector Machine Methods, Kuldeep Kaur, Ashok Kumar, Baldev Singh, M. Godarzi
The Thai Journal of Pharmaceutical Sciences
Three chemometric methods; partial least squares regression (PLS), principal component regression (PCR) and least-squares support vector machines (LS-SVM) were applied for simultaneous determination of carbidopa and levodopa in synthetic mixtures and rea...
Author Index, Keyword Index, N/A
Author Index, Keyword Index, N/A
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Flavonoid Glycosides From The Leaves Of Uvaria Rufa With Advanced Glycation End-Products Inhibitory Activity, Khanittha Deepralard, Kazuko Kawanishi, Masataka Moriyasu, Thitima Pengsuparp, Rutt Suttisri
Flavonoid Glycosides From The Leaves Of Uvaria Rufa With Advanced Glycation End-Products Inhibitory Activity, Khanittha Deepralard, Kazuko Kawanishi, Masataka Moriyasu, Thitima Pengsuparp, Rutt Suttisri
The Thai Journal of Pharmaceutical Sciences
Prolonged hyperglycemia in diabetic patients leads to the formation of advanced glycation end-products (AGEs) in their body tissues, which contribute to the development and progression of diabetic complications and aging. Preliminary screening of the eth...
Bioequivaience Study Of Two Different Formulations Of 300 Mg Gabapentin Capsule In Thai Healthy Volunteers, Supeecha Wittayalertpanya, Sumana Chompootaweep, Nongnuch Thaworn, Wondee Khemsri, Nantana Intanil
Bioequivaience Study Of Two Different Formulations Of 300 Mg Gabapentin Capsule In Thai Healthy Volunteers, Supeecha Wittayalertpanya, Sumana Chompootaweep, Nongnuch Thaworn, Wondee Khemsri, Nantana Intanil
The Thai Journal of Pharmaceutical Sciences
The objective of this study was to compare the bioavailability of new generic product of gabapentin with the innovator’s product. The study was performed in 20 Thai male healthy volunteers who received a single oral dose of 300 mg gabapentin capsule. D...
The Role Of National Science Journals: Information, Advocacy And Education, Alexander T. Florence
The Role Of National Science Journals: Information, Advocacy And Education, Alexander T. Florence
The Thai Journal of Pharmaceutical Sciences
No abstract provided.