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Articles 271 - 300 of 1530
Full-Text Articles in Pharmacology
Effects Of The Standardized Extract Of Centella Asiatica Eca233 On Hepatic Phase Ii Drug-Metabolizing Enzymes In Rats, Pitchayapa Seeka, Nuansri Niwattisaiwong, Mayuree H. Tantisira, Songpol Chevapat, Kridsada Anuntawuttikul, Khemchat Apipalakul, Somsong Lawanprasert
Effects Of The Standardized Extract Of Centella Asiatica Eca233 On Hepatic Phase Ii Drug-Metabolizing Enzymes In Rats, Pitchayapa Seeka, Nuansri Niwattisaiwong, Mayuree H. Tantisira, Songpol Chevapat, Kridsada Anuntawuttikul, Khemchat Apipalakul, Somsong Lawanprasert
The Thai Journal of Pharmaceutical Sciences
The standardized extract of C. asiatica ECa233 (ECa 233) was shown to possess neuroprotective and wound healing effects. The purpose of this study was to investigate effects ECa 233 on the activities of phase II drug metabolizing enzymes including UDP-gl.
Application Of Ion-Pair Complexation Reaction For The Spectrophotometric Determination Of Clarithromycin In Pharmaceutical Formulations, Sameer A. M. Abdulrahman
Application Of Ion-Pair Complexation Reaction For The Spectrophotometric Determination Of Clarithromycin In Pharmaceutical Formulations, Sameer A. M. Abdulrahman
The Thai Journal of Pharmaceutical Sciences
Two simple, rapid, sensitive, selective and extraction-free spectrophotometric methods have been developed for the determination of clarithromycin (CLR) both in pure form and in pharmaceutical formulations. The developed methods are based on ion-pair com.
High-Performance Thin-Layer Chromatography Analysis Of (E)-4-(3?,4?-Dimethoxyphenyl)But-3-En-1-Ol (Compound D) In Zingiber Cassumunar Roxb Rhizome Extract: An Application On Genetic Differentiation, Prasan Tangyuenyongwatana, Piyarat Parinyapong Chareonsap, Wandee Gritsanapan
High-Performance Thin-Layer Chromatography Analysis Of (E)-4-(3?,4?-Dimethoxyphenyl)But-3-En-1-Ol (Compound D) In Zingiber Cassumunar Roxb Rhizome Extract: An Application On Genetic Differentiation, Prasan Tangyuenyongwatana, Piyarat Parinyapong Chareonsap, Wandee Gritsanapan
The Thai Journal of Pharmaceutical Sciences
Objectives: This study focused on developing high performance thin-layer chromatography (HPTLC) quantitative analysis method for compound D, a major anti-inflammatory compound in Zingiber cassumunar extract. In addition, the amplified fragment length pol.
Hepatoprotective And Hepatoregenerative Therapeutic Effects Of Polyherbal Medicine Heparmin Tm On Rattus Norvegicus Wistar With Liver Fibrosis, Diana Lyrawati, Amalia Ghassani Muslimah, Dewi Laksmita, Dian Indrawati Santoso, Erlien Lindawati Poernomo, Karina Larasati, Lina Zahrotus Sajidah, Oktavia Rahayu Adianingsih, Rosida Dewi Agusningtyas, Mudjiwijono Handaru Eko, Bogi Pratomo Wibowo
Hepatoprotective And Hepatoregenerative Therapeutic Effects Of Polyherbal Medicine Heparmin Tm On Rattus Norvegicus Wistar With Liver Fibrosis, Diana Lyrawati, Amalia Ghassani Muslimah, Dewi Laksmita, Dian Indrawati Santoso, Erlien Lindawati Poernomo, Karina Larasati, Lina Zahrotus Sajidah, Oktavia Rahayu Adianingsih, Rosida Dewi Agusningtyas, Mudjiwijono Handaru Eko, Bogi Pratomo Wibowo
The Thai Journal of Pharmaceutical Sciences
Chronic injury severely impairs liver regeneration through excess inflammation, scarring and epithelial abnormalities, since injured cells may shift response from pro-regeneration into pro-fibrosis which leads to cirrhosis and total liver failure. An Ind.
Simple And Rapid Spectrophotometric Method For Quality Determination Of Roselle (Hibiscus Sabdariffa), Tasamaporn Sukwattanasinit, Jankana Burana-Osot, Uthai Sotanaphun
Simple And Rapid Spectrophotometric Method For Quality Determination Of Roselle (Hibiscus Sabdariffa), Tasamaporn Sukwattanasinit, Jankana Burana-Osot, Uthai Sotanaphun
The Thai Journal of Pharmaceutical Sciences
A simple and rapid spectrophotometric method has been developed to determine the quality of roselle (Hibiscus sabdariffa). The absorbance at 530 nm (coloring intensity) and the ratio between the absorbances at 380 and 530 nm (degradation index) of its 5...
Molecular Docking Study Of Tyrosinase Inhibitors Using Arguslab 4.0.1 : A Comparative Study, Prasan Tangyuenyongwatana, Nathjanan Jongkon
Molecular Docking Study Of Tyrosinase Inhibitors Using Arguslab 4.0.1 : A Comparative Study, Prasan Tangyuenyongwatana, Nathjanan Jongkon
The Thai Journal of Pharmaceutical Sciences
We conducted a docking study with ArgusLab 4.0.1, a free molecular docking software, on tyrosinase inhibitors comparing with AutoDock 4 and AutoDock VINA. In this study, hydroxyl substituted 2-phenyl-naphthalenes (a group of modified structure based on o...
Tlc-Densitometric Method For Quantitation Of Lurasidone Hydrochloride In Nanoemulsion, Microemulsion, For Equilibrium Solubility And Ex Vivo Diffusion Studies., Rashmin B. Patel, Khyati B. Vekaria, Mrunali R. Patel
Tlc-Densitometric Method For Quantitation Of Lurasidone Hydrochloride In Nanoemulsion, Microemulsion, For Equilibrium Solubility And Ex Vivo Diffusion Studies., Rashmin B. Patel, Khyati B. Vekaria, Mrunali R. Patel
The Thai Journal of Pharmaceutical Sciences
A new TLC-densitometric method has been successfully developed for quantitation of Lurasidone hydrochloride (LURHA) in pharmaceutical formulations. LURHA was well separated from sample matrix and degradation product using TLC plate; precoated with silica...
Mucus Secretion Stimulation: A Mechanism In Gastroprotective Effect Of Zingiber Officinale, Gaewbpragaan Chantharangsikul, Worawan Kitpati, Noppamas Soonthornchareonnon, Achariya Sailasuta, Arunporn Itharat, Wisuda Suvitayavat
Mucus Secretion Stimulation: A Mechanism In Gastroprotective Effect Of Zingiber Officinale, Gaewbpragaan Chantharangsikul, Worawan Kitpati, Noppamas Soonthornchareonnon, Achariya Sailasuta, Arunporn Itharat, Wisuda Suvitayavat
The Thai Journal of Pharmaceutical Sciences
There are several studies on the gastroprotective effect of Z. officinale, however, the nature of this effect has not been fully elucidated. The present study investigated the gastroprotective activity and underlying mechanism of the 95% ethanolic extrac...
Validation Of An Rp-Hplc Method For Quantitative Analysis Of Phikud Navakot Extract Using The Standard Addition Method, Pavena Kumnerdnon, Pornchai Rojsitthisak, Nuansri Niwattisaiwong, Uthai Sotanaphun, Jittima Chatchawalsaisin, Narueporn Sutanthavibul
Validation Of An Rp-Hplc Method For Quantitative Analysis Of Phikud Navakot Extract Using The Standard Addition Method, Pavena Kumnerdnon, Pornchai Rojsitthisak, Nuansri Niwattisaiwong, Uthai Sotanaphun, Jittima Chatchawalsaisin, Narueporn Sutanthavibul
The Thai Journal of Pharmaceutical Sciences
The aim of the study was to develop a reversed phase-high performance liquid chromatography (RP-HPLC) analytical method for monitoring three analytical markers, gallic acid, vanillic acid and ferulic acid, in Phikud Navakot extract (NVK-E), using the sta...
Comparison Of Sedimentation Stability Of Ampicillin Trihydrate Suspensions Using Near Infrared Extinction Profiles, Padala Narasimha Murthy, Meduri Vimala Devi, Sudhir Kumar Sahoo, Anjan Kumar Mahapatra, Madhusmruti Khandai
Comparison Of Sedimentation Stability Of Ampicillin Trihydrate Suspensions Using Near Infrared Extinction Profiles, Padala Narasimha Murthy, Meduri Vimala Devi, Sudhir Kumar Sahoo, Anjan Kumar Mahapatra, Madhusmruti Khandai
The Thai Journal of Pharmaceutical Sciences
Suspensions are one of the most important and popular dosage forms. A large number of drugs are formulated in the form of suspensions and are available commercially. Stability studies of suspensions are very important to enable the patient to receive t...
Herbs Used As A Cure For Rheumatiod Arthritis: A Review, Santhosh Aruna Mamidi
Herbs Used As A Cure For Rheumatiod Arthritis: A Review, Santhosh Aruna Mamidi
The Thai Journal of Pharmaceutical Sciences
Rheumatoid arthritis is chronic, progressive, disabling autoimmune disease characterized by systemic inflammation of joints, damaging cartilage and bone around the joints. It is a systemic disease which means that it can affect the whole body and interna...
Effects Of Continuous Exposure To Bisphenol A On Male And Female Mice From Prenatally To Adulthood, Kannikar Chatsantiprapa, Tip-Arpa Sophon, Jintana Sattayasai
Effects Of Continuous Exposure To Bisphenol A On Male And Female Mice From Prenatally To Adulthood, Kannikar Chatsantiprapa, Tip-Arpa Sophon, Jintana Sattayasai
The Thai Journal of Pharmaceutical Sciences
BisphenolA (BPA), a monomer estrogenic chemical of many plastic products has controversial biological effects. This study assessed the effects at 0.05 mg/kg BW/day (Tolerable Daily Intake, TDI) and 0.5 mg/kg BW/day (10TDI), in male and female mice contin...
Outcomes Of Pharmaceutical Care Services In Promoting Rational Drug Use, Wanna Sriviriyanupap, Roungtiva Muenpa
Outcomes Of Pharmaceutical Care Services In Promoting Rational Drug Use, Wanna Sriviriyanupap, Roungtiva Muenpa
The Thai Journal of Pharmaceutical Sciences
Pharmacists provide pharmaceutical care service in order to support rational drug use. However, still lack of evidence to show its outcomes. Therefore, this cross-sectional descriptive study and qualitative study were conducted to evaluate the outcomes o...
Calotropis Procera: A Phytochemical And Pharmacological Review, Neelam Balekar
Calotropis Procera: A Phytochemical And Pharmacological Review, Neelam Balekar
The Thai Journal of Pharmaceutical Sciences
Medicinal plants are used from the ancient time as the major sources of drugs.The fact is that we can obtain many of the presently available drugs, either directly in the extract form or in the modified synthetic form. Naturally, plants have ability to s...
Effect Of Fat Content On Characteristics Of Ice Cream Fortified With Calcium And Vitamin D3, Rossarin Tansawat
Effect Of Fat Content On Characteristics Of Ice Cream Fortified With Calcium And Vitamin D3, Rossarin Tansawat
The Thai Journal of Pharmaceutical Sciences
Calcium and vitamin D play important roles in bone homeostasis. Several studies reported inadequate intakes of these two nutrients in many population groups. Food fortification is one way to solve the problem. The objective of this study was to develop...
Exploring Knowledge Acquisition Technique For New Start-Up Community Food Enterprises, Wattanapong Luechoowong, Ruangthip Tantipidoke, Rungpetch Sakulbumrungsil
Exploring Knowledge Acquisition Technique For New Start-Up Community Food Enterprises, Wattanapong Luechoowong, Ruangthip Tantipidoke, Rungpetch Sakulbumrungsil
The Thai Journal of Pharmaceutical Sciences
Objective: This qualitative study is conducted to explore the knowledge acquisition techniques from five successful food enterprises at the new entry of community business. Methods: Five successful community food producers were purposively selected unde...
Stilbenoids From The Stem Of Diospyros Collinsae, The First Evidence For The Production Of Stilbene Derivatives In Ebenaceous Plants, Buntita Bumroong, Witchuda Thanakijcharoenpath
Stilbenoids From The Stem Of Diospyros Collinsae, The First Evidence For The Production Of Stilbene Derivatives In Ebenaceous Plants, Buntita Bumroong, Witchuda Thanakijcharoenpath
The Thai Journal of Pharmaceutical Sciences
Two stilbenoids, diptoindonesin D (1) and diptoindonesin G (2), were isolated from the stem of Diospyros collinsae Craib (Ebenaceae), together with four triterpenoids, namely friedelin, lupeol, betulin and betulinic acid. Their structures were determined...
Exploring Key Factors Affecting The Competitiveness Of Thailand’S Cosmetic Industry, Neeranard Jinachai, Win Winit-Watjana, Puree Anantachoti
Exploring Key Factors Affecting The Competitiveness Of Thailand’S Cosmetic Industry, Neeranard Jinachai, Win Winit-Watjana, Puree Anantachoti
The Thai Journal of Pharmaceutical Sciences
The Thai cosmetic industry has continuously grown, but relevant factors impacting on the industry remained un-assessed. This study was intended to explore key factors affecting the country competitiveness. The Diamond model was adapted as the conceptual ...
Anaphylactic Shock Caused By A Selective Allergy To Ceftriaxone: A Case Report, Wichai Santimaleeworagun
Anaphylactic Shock Caused By A Selective Allergy To Ceftriaxone: A Case Report, Wichai Santimaleeworagun
The Thai Journal of Pharmaceutical Sciences
Ceftriaxone has been wildly used due to once daily dosing. However, case with anaphylaxis secondary to ceftriaxone has been documented and the other β-lactam might be caution. We reported an 89 year-old patient who had history of type I hypersensitivity...
Comparative Evaluation Of Neuroprotective Effect Of Three Varieties Of Allium Cepa In Chronic Constriction Injury Induced Neuropathic Pain, Amit Kumar, Kundan Singh Bora, Amteshwar Singh Jaggi, Richa Shri
Comparative Evaluation Of Neuroprotective Effect Of Three Varieties Of Allium Cepa In Chronic Constriction Injury Induced Neuropathic Pain, Amit Kumar, Kundan Singh Bora, Amteshwar Singh Jaggi, Richa Shri
The Thai Journal of Pharmaceutical Sciences
Objectives: Allium cepa has been used extensively for culinary purposes as well as in traditional system of medicine. A number of varieties of A. cepa are available commercially with varietal differences in phytoconstituents and biological activities. Ho...
Effect Of Time-Dependent Polymer On The Dissolution Rate Of Flurbiprofen: Formulation And Evaluation Of Colon-Specific Matrix Tablets, Sateesh Kumar Vemula, Selamu Kebamo, Balisa Mosisa, Biniam Paulos
Effect Of Time-Dependent Polymer On The Dissolution Rate Of Flurbiprofen: Formulation And Evaluation Of Colon-Specific Matrix Tablets, Sateesh Kumar Vemula, Selamu Kebamo, Balisa Mosisa, Biniam Paulos
The Thai Journal of Pharmaceutical Sciences
An effort was made in the present study to prepare flurbiprofen matrix tablets to improve the therapeutic efficacy by increasing therapeutic drug concentrations in lower intestine i.e., site-specific release to colon. The current experiment was aimed to ...
Qsar Study On Quinolinecarbaldehyde Derivatives As Potential Anti-Tubercular Agents, Ravichandran Veerasamy, Shalini Sivadasan, Venakteskumar Krishnamoorthi, Harish Rajak, Sureshkumar Krishnan
Qsar Study On Quinolinecarbaldehyde Derivatives As Potential Anti-Tubercular Agents, Ravichandran Veerasamy, Shalini Sivadasan, Venakteskumar Krishnamoorthi, Harish Rajak, Sureshkumar Krishnan
The Thai Journal of Pharmaceutical Sciences
This study investigated the quantitative structure–activity relationships (QSAR) for a range of substituted quinolinecarbaldehyde derivatives as anti-tubercular agent by multiple linear regression analysis. The derived QSAR models have been statistical...
Synthesis And Evaluation Of Pi3kγ Enzyme Inhibitory Activity Of Novel (1h-Pyrazol-4-Yl)Methanamine, Sukumar Bepary, In Kwon Youn, Hee-Jong Lim, Ge Hyeong Lee
Synthesis And Evaluation Of Pi3kγ Enzyme Inhibitory Activity Of Novel (1h-Pyrazol-4-Yl)Methanamine, Sukumar Bepary, In Kwon Youn, Hee-Jong Lim, Ge Hyeong Lee
The Thai Journal of Pharmaceutical Sciences
A series of (1H-pyrazol-4-yl)methanamines have been synthesized and then were evaluated for the PI3Kγ enzyme inhibitory potential. Minor modification of the initially synthesized molecules offered significant improvement of the inhibitory potential from...
Cross Immediate Hypersensitivity Between Ciprofloxacin And Levofloxacin: A Case Report And Literature Review, Chotirat Nakaranurack
Cross Immediate Hypersensitivity Between Ciprofloxacin And Levofloxacin: A Case Report And Literature Review, Chotirat Nakaranurack
The Thai Journal of Pharmaceutical Sciences
Fluoroquinolones can show cross-reactivity because of the similar chemical structure. Levofloxacin is a new fluoroquinolone and can be a safe alternative due to low cross-reactivity. This is a case report showing cross-reactivity between ciprofloxacin an...
Development Of Miconazole Nitrate Loaded Micellar Gel For Improved Topical Delivery, Manish Kumar
Development Of Miconazole Nitrate Loaded Micellar Gel For Improved Topical Delivery, Manish Kumar
The Thai Journal of Pharmaceutical Sciences
The objective of the present investigation was to develop micellar gel of miconazole nitrate using amphiphilic block co-polymer pluronic F-127. Miconazole nitrate was entrapped into the micelles at critical micelle concentration by dialysis method and F2...
Pharmacy Students’ Attitudes And Perceptions About Complementary And Alternative Medicine: A Systematic Review, Mohd Shahezwan Abd Wahab, Phantipa Sakthong, Win Winit-Watjana
Pharmacy Students’ Attitudes And Perceptions About Complementary And Alternative Medicine: A Systematic Review, Mohd Shahezwan Abd Wahab, Phantipa Sakthong, Win Winit-Watjana
The Thai Journal of Pharmaceutical Sciences
Complementary and alternative medicine (CAM) is extensively used worldwide. The attitudes and perceptions of pharmacy students about CAM may influence their practices upon graduation. In this work, a systematic review was conducted by searching available...
Hepatoprotective And Nephrotoxic Effects Of Methanol Leaf Extract Of Telfairia Occidentalis (Hook F.) In Adult Female Albino Rats (Rattus Norvegicus), Chidozie Nwabuisi Okoye, John Ikechukwu Ihedioha, Onyinyechukwu Ada Agina, Izuchukwu Ochiogu, David Ogwu
Hepatoprotective And Nephrotoxic Effects Of Methanol Leaf Extract Of Telfairia Occidentalis (Hook F.) In Adult Female Albino Rats (Rattus Norvegicus), Chidozie Nwabuisi Okoye, John Ikechukwu Ihedioha, Onyinyechukwu Ada Agina, Izuchukwu Ochiogu, David Ogwu
The Thai Journal of Pharmaceutical Sciences
The leaf extract of the plant Telfairia occidentalis, commonly known as fluted pumpkin is used as a hematinic by post-menstrual and pregnant women and for treatment of many different ailments with little consideration of their toxic potentials. This stud...
Predicting The Duration Of Antibacterial Treatment With Cell Wall Synthesis Inhibitors By Using Mathematical Models, Panit Suavansri
Predicting The Duration Of Antibacterial Treatment With Cell Wall Synthesis Inhibitors By Using Mathematical Models, Panit Suavansri
The Thai Journal of Pharmaceutical Sciences
This paper proposed a new mathematical model of within-host population dynamics of bacteria after cell wall synthesis inhibitors administration for practically predicting treatment duration and drug dosage. Our model deployed various concepts from differ...
Developing A Signal Triage Algorithm For Thai National Adverse Drug Reaction Database, Suntharee T. Chaisumritchoke
Developing A Signal Triage Algorithm For Thai National Adverse Drug Reaction Database, Suntharee T. Chaisumritchoke
The Thai Journal of Pharmaceutical Sciences
There was increasing adverse drug reaction (ADR) reports submitted to the Health Product Vigilance Center under the Thai FDA. In order to find some signals, the Thai Signal Detection Program was developed to identify and filter the potential signals, cal...
Factors Affecting Community Pharmacists’ Intention To Provide Medication Management Program And Disease Screening In Bangkok, Payungjit Kangwol, Puree Anantachoti
Factors Affecting Community Pharmacists’ Intention To Provide Medication Management Program And Disease Screening In Bangkok, Payungjit Kangwol, Puree Anantachoti
The Thai Journal of Pharmaceutical Sciences
Objectives: To determine factors affecting community pharmacists’ intention to provide medication management program (MMP) and disease screening (DS) based on diffusion of innovations theory. Methods: A cross-sectional study using self-administered ma...