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Articles 241 - 270 of 1530
Full-Text Articles in Pharmacology
Anti-Inflammatory Effect Of Centella Asiatica Extract On Prevented Aortic Intima-Media Thickening In Diabetic Rats, Amalia Anita Hawas, Dwi Aris Agung Nugrahaningsih, Eti Nurwening Sholikhah, Sadli Syarifuddin, Rahmi Ayu Wijayaningsih, Ngatidjan
Anti-Inflammatory Effect Of Centella Asiatica Extract On Prevented Aortic Intima-Media Thickening In Diabetic Rats, Amalia Anita Hawas, Dwi Aris Agung Nugrahaningsih, Eti Nurwening Sholikhah, Sadli Syarifuddin, Rahmi Ayu Wijayaningsih, Ngatidjan
The Thai Journal of Pharmaceutical Sciences
Objectives: To explore the effect of C. asiatica extract on intima-media thickness, eNOS expression, and macrophage M1/M2 ratio in diabetic rats aorta. Materials and Methods: Wistar rats consisted of normal group and diabetic group which divided into neg.
Effect Of Ipomoea Hederacea Jacq. Methanolic Extract On Blood Pressure And Relaxation Of Rat Thoracic Aorta: Evidence Indicated The Release Of No And H2s, Chaweewan Jansakul
Effect Of Ipomoea Hederacea Jacq. Methanolic Extract On Blood Pressure And Relaxation Of Rat Thoracic Aorta: Evidence Indicated The Release Of No And H2s, Chaweewan Jansakul
The Thai Journal of Pharmaceutical Sciences
Seeds of Ipomoeahederacea Jacq. (IH) are used in traditional medicine to manage ailments pertaining to the vasculature, circulatory system and related disorders. However no study exists to validate their usage for said ailments. The present study was con.
Solubilization Of Fluocinolone Acetonide By Cosolvents And Surfactants For Buccal Solution Preparation, Pornpen Werawatganone, Walaisiri Muangsiri, Tipanan Chaivanon, Pavinee Kungwanpongpun, Paricha Rattanawong
Solubilization Of Fluocinolone Acetonide By Cosolvents And Surfactants For Buccal Solution Preparation, Pornpen Werawatganone, Walaisiri Muangsiri, Tipanan Chaivanon, Pavinee Kungwanpongpun, Paricha Rattanawong
The Thai Journal of Pharmaceutical Sciences
Fluocinolone acetonide (FA) buccal solution was prepared for treatment of oral lichen planus using cosolvents and surfactant to enhance FA solubility. Based on solubility power (s), cosolvents enhanced FA solubility in the order; polyethylene glycol 400 .
Antioxidant Potential Of Wild Lagenaria Siceraria (Molina) Standl, Suraj B. Patel, Usmangani A. Attar, S G. Ghane
Antioxidant Potential Of Wild Lagenaria Siceraria (Molina) Standl, Suraj B. Patel, Usmangani A. Attar, S G. Ghane
The Thai Journal of Pharmaceutical Sciences
Objective: The aim of the present study was to evaluate the phytochemicals and antioxidant activity of leaf and fruit of wild Bottle gourd. Methods: Successive extraction of dried material was done by soxhlet apparatus and phytochemicals such as total p..
Study Of Antioxidant, Antimicrobial, Tyrosinase Inhibitory, Alcohol Dehydrogenase, And Acetaldehyde Dehydrogenase Activity Of Roasted Dendropanax Morbifera Lev. Leaves With Different Ethanol Concentrations, Masaya Nakamura, Ra Jong-Hwan, Kim Ju-Sung
Study Of Antioxidant, Antimicrobial, Tyrosinase Inhibitory, Alcohol Dehydrogenase, And Acetaldehyde Dehydrogenase Activity Of Roasted Dendropanax Morbifera Lev. Leaves With Different Ethanol Concentrations, Masaya Nakamura, Ra Jong-Hwan, Kim Ju-Sung
The Thai Journal of Pharmaceutical Sciences
Introduction: The history of Dendropanax morbifera LEV., which is indigenous plant in Korea, is quit old and simultaneously, known for locals as remedy of various diseases such as migraine and inflammation. The aim of this study is evaluating the antioxi.
Quick-Fat Diet Inhibits The Development Of Diabetes In Spontaneously Diabetic Torii (Sdt) Rats, Takeshi Ohta, Takahisa Yamada, Taiichiro Kamiya, Takayuki Gotoh, Masataka Tsubaki, Masami Shinohara
Quick-Fat Diet Inhibits The Development Of Diabetes In Spontaneously Diabetic Torii (Sdt) Rats, Takeshi Ohta, Takahisa Yamada, Taiichiro Kamiya, Takayuki Gotoh, Masataka Tsubaki, Masami Shinohara
The Thai Journal of Pharmaceutical Sciences
The diabetic animal model is very useful for developing functional foods and medicinal drugs. Spontaneously Diabetic Torii (SDT) rat, a non-obese type 2 diabetic model, is one of the hopeful models to play an important role for research and development o.
Hepatoprotective Activity Of Curcuma Xanthorrhiza Roxb. Paracetamol-Induced Liver Damage In Rats And Correlation With Their Chemical Compounds, Suwijiyo Pramono, Fitriana Hayyu Arifah, Fitrawan Hernuza Pribadi, Agung Endro Nugroho
Hepatoprotective Activity Of Curcuma Xanthorrhiza Roxb. Paracetamol-Induced Liver Damage In Rats And Correlation With Their Chemical Compounds, Suwijiyo Pramono, Fitriana Hayyu Arifah, Fitrawan Hernuza Pribadi, Agung Endro Nugroho
The Thai Journal of Pharmaceutical Sciences
Paracetamol is a widely used drug, but at high dose, it can produce undesirable side effects such as hepatotoxicity. Curcuma xanthorrhiza Roxb. is the one of Indonesian medicinal plants that traditionally used to treat liver disorders. The present study .
Determination Of Potency Of Tetanus Immunoglobulin Products By Commercial Tetanus Anti-Toxoid Test Kits, Wichuda Jariyapan, Kanitta Puwanardnaranuban, Saywarul Jadoonkittnan
Determination Of Potency Of Tetanus Immunoglobulin Products By Commercial Tetanus Anti-Toxoid Test Kits, Wichuda Jariyapan, Kanitta Puwanardnaranuban, Saywarul Jadoonkittnan
The Thai Journal of Pharmaceutical Sciences
Replacement of using experimental animals in scientific research with alternative methods is encouraged, according to the ‘3Rs’ principles (replacement, reduction and refinement). This study presented results for determination of potency of tetanus i...
New Fluorinated Chalcone And Pyrazolines Analogues: Synthesis, Docking And Molecular Dynamic Studies As Anticancer Agents, Jasril Jasril
New Fluorinated Chalcone And Pyrazolines Analogues: Synthesis, Docking And Molecular Dynamic Studies As Anticancer Agents, Jasril Jasril
The Thai Journal of Pharmaceutical Sciences
Some of chalcones and pyrazolines analogues are known to have a good potency as anticancer agents. In this work, a fluorinated chalcone and two pyrazolines were successfully synthesized under microwave irradiation. Molecular docking and molecular dynamic.
Influence Of Disease-Related Knowledge And Personality Traits On Parkinson’S Patient Empowerment, Pramon Viwattanakulvanid, Tanattha Kittisopee
Influence Of Disease-Related Knowledge And Personality Traits On Parkinson’S Patient Empowerment, Pramon Viwattanakulvanid, Tanattha Kittisopee
The Thai Journal of Pharmaceutical Sciences
Background: Parkinson’s disease (PD), a neurodegenerative disorder, has an impact on both the physical and mental functions of persons with Parkinson’s (PwP), who tend to lose their sense of empowerment, cognitive state of perceived competence and pe...
Stability Determination Of An Alternative Approach To Use Of Liquid Drug Substance As Oil Phase In Microemulsion Formulations: Methyl Salicylate, Warunee Leesajakul, Sunee Channarong, Pathamaporn Chuetee
Stability Determination Of An Alternative Approach To Use Of Liquid Drug Substance As Oil Phase In Microemulsion Formulations: Methyl Salicylate, Warunee Leesajakul, Sunee Channarong, Pathamaporn Chuetee
The Thai Journal of Pharmaceutical Sciences
The objective of this study was to investigate the stability of microemulsions using methyl salicylate as oil phase in the presence and the absence of hydrophobic additives and/or drug after six-month storage at ambient temperature. The investigated addi.
Systematic Extraction And Characterization Of ?-Glucan From The Industrial Brewing Yeast (Saccharomyces Cerevisiae) Waste Material And The Immunomodulatory Studies On Tnf-? And Il-6 Cytokine Balance Of The Mouse Macrophage Cell Lines, Theeraya Krisdaphong
The Thai Journal of Pharmaceutical Sciences
Objectives: The aim of this investigation was to create value to the industrial waste production by systematic extraction and purification of ?-glucan from the industrial brewing yeast (Saccharomyces cerevisiae) waste material. In addition, the immunolo..
Extra Precision Docking Studies Of Novel Luteolin Analogues For The Inhibition Of Tankyrase Ii- “A Theoretical Based Approach Towards Novel Cancer Target, Aravinda Pai, Jayashree B.S., Sanchari Basu-Mallik, Richard Lobo
Extra Precision Docking Studies Of Novel Luteolin Analogues For The Inhibition Of Tankyrase Ii- “A Theoretical Based Approach Towards Novel Cancer Target, Aravinda Pai, Jayashree B.S., Sanchari Basu-Mallik, Richard Lobo
The Thai Journal of Pharmaceutical Sciences
Luteolin, a natural bio-flavonoid is known to possess variety of pharmacological activity, particularly tumour growth inhibition. Reports are available to substantiate the interaction of luteolin with Tankyrase II, one of the key enzymes responsible for .
Clinical Outcomes Of A Pharmaceutical Care Service In Lithium Clinic Adjunct To Standard Care Compared With Standard Care Alone In Patients With Bipolar Disorder: 10 Years Naturalistic Retrospective Cohort Study, Orabhorn Suanchang, Vithaya Kulsomboon, Yupadee Sirisinsuk, Norrawee Phoomchan, Charnwit Skawatananont
Clinical Outcomes Of A Pharmaceutical Care Service In Lithium Clinic Adjunct To Standard Care Compared With Standard Care Alone In Patients With Bipolar Disorder: 10 Years Naturalistic Retrospective Cohort Study, Orabhorn Suanchang, Vithaya Kulsomboon, Yupadee Sirisinsuk, Norrawee Phoomchan, Charnwit Skawatananont
The Thai Journal of Pharmaceutical Sciences
Objective: To compare the long-term clinical outcomes of bipolar patients following lithium maintenance therapy between patients who received standard care plus pharmaceutical care service (lithium clinic group) and patients who received standard care al.
Isocratic Ultra-Performance Liquid Chromatographic Assay Of Quetiapine Fumarate In Pharmaceuticals, N Rajendra Prasad, Kanakapura Basavaiah
Isocratic Ultra-Performance Liquid Chromatographic Assay Of Quetiapine Fumarate In Pharmaceuticals, N Rajendra Prasad, Kanakapura Basavaiah
The Thai Journal of Pharmaceutical Sciences
An isocratic and reversed phase ultra-performance liquid chromatographic (RP-UPLC) method has been developed for the determination of quetiapine fumarate (QTF)) in bulk drug and in its tablets. The method was developed using AQUITY UPLC HSS T3 (2.1 x 50.
Stability-Indicating Method To Determine Bioactive Nucleosides In Crude Drugs, Extracts, And Products From Cordyceps Sinensis And Cordyceps Militaris, Boonta Chutvirasakul
Stability-Indicating Method To Determine Bioactive Nucleosides In Crude Drugs, Extracts, And Products From Cordyceps Sinensis And Cordyceps Militaris, Boonta Chutvirasakul
The Thai Journal of Pharmaceutical Sciences
The aim of this study was to develop a stability indicating method to determine bioactive nucleosides including uridine, guanosine, adenosine, and cordycepin in crude drugs, extracts, and products from Cordyceps Sinensis and Cordyceps Militaris by gradie.
A Medicines Terminology Governance Model For Thailand, Anuchai Theeraroungchaisri, Ratsapan Phuksaritanon, Boonchai Kijsanayotin
A Medicines Terminology Governance Model For Thailand, Anuchai Theeraroungchaisri, Ratsapan Phuksaritanon, Boonchai Kijsanayotin
The Thai Journal of Pharmaceutical Sciences
At present, Thailand does not have a national governance system for developing a health data standard and coding system, especially drug codes and medicine terminology. There is no single responsible organization and also no mechanism for cooperation amo.
Virtual Screening For Novel 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitors: A Shape-Based Search Approach, Prasan Tangyuenyongwatana, Wandee Gritsanapan
Virtual Screening For Novel 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitors: A Shape-Based Search Approach, Prasan Tangyuenyongwatana, Wandee Gritsanapan
The Thai Journal of Pharmaceutical Sciences
A virtual screening study with ArgusLab 4.0.1 was performed on 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR), the second enzyme in the methyl erythritol phosphate pathway in isoprenoids production which is present in malarial parasite Plasmodium .
Chemical Compositions And Repellent Activity Of Eucalyptus Tereticornis And Eucalyptus Deglupta Essential Oils Against Culex Quinquefasciatus Mosquito, Rini Pujiarti, Rini Pujiarti
Chemical Compositions And Repellent Activity Of Eucalyptus Tereticornis And Eucalyptus Deglupta Essential Oils Against Culex Quinquefasciatus Mosquito, Rini Pujiarti, Rini Pujiarti
The Thai Journal of Pharmaceutical Sciences
Eucalyptus oils have distinctive smell that not preferably by mosquito and able to repellent mosquito. This research was evaluated chemical compositions and repellent activity of Eucalyptus tereticornis and Eucalyptus deglupta oils against C. quinquefasc.
Time-Kill Study Of The In Vitro Antimicrobial Activity Of Tedizolid Against Methicillin-Resistant Staphylococcus Aureus, Tanawat Nunart, Tanitta Chatsuwan, Wanchai Treyaprasert
Time-Kill Study Of The In Vitro Antimicrobial Activity Of Tedizolid Against Methicillin-Resistant Staphylococcus Aureus, Tanawat Nunart, Tanitta Chatsuwan, Wanchai Treyaprasert
The Thai Journal of Pharmaceutical Sciences
To evaluate the in vitro antimicrobial activity of tedizolid against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) by time-kill curve experiments. Four bacterial strains were used in methicillin susceptibility tests, including M.
Effects Of Family Pharmacy Intervention On Clinical Outcomes In Primary Care Settings In Thailand, Wiwat Thavornwattanayong, Namfon Sribundit
Effects Of Family Pharmacy Intervention On Clinical Outcomes In Primary Care Settings In Thailand, Wiwat Thavornwattanayong, Namfon Sribundit
The Thai Journal of Pharmaceutical Sciences
Background Despite pharmaceutical care had positive effect on improving patient health, currently data fact sheet illustrate slightly increasing of uncontrolled diabetes and uncontrolled hypertension among Thai elderly. Family pharmacist applied more ef..
Vanillin Increases Stem Cell Signal And Cell Adhesion In Keratinocytes, Supak Taboonpong, Chayanin Kiratipaiboon, Preeyaporn Plaimee Phiboonchaiyanan, Premjit Junthongjin, Pornlert Trithossadech, Pithi Chanvorachote
Vanillin Increases Stem Cell Signal And Cell Adhesion In Keratinocytes, Supak Taboonpong, Chayanin Kiratipaiboon, Preeyaporn Plaimee Phiboonchaiyanan, Premjit Junthongjin, Pornlert Trithossadech, Pithi Chanvorachote
The Thai Journal of Pharmaceutical Sciences
Keratinocyte stem cells residing in the basal layer of the epidermis are thought to function in the process of the epidermis renewal and maintain the barrier property of the skin. This study has explored for the first time that vanillin, a natural compou.
Effect Of Different Production Variables On The Physical Properties Of Pellets Prepared By Extrusion-Spheronization Using A Multivariate Analysis, John Rojas
The Thai Journal of Pharmaceutical Sciences
The spheronization process has been widely used in recent years in multiparticulate oral formulations because it is a simple and rapid technology. It offers advantages over other dosage forms such as tablets due to the more uniform and predictable transp.
Docking, Synthesis, And Cytotoxic Activity Of N-4-Methoxybenzoyl-N’-(4-Fluorophenyl)Thiourea On Hela Cell Line, Anindi Lupita Nasyanka
Docking, Synthesis, And Cytotoxic Activity Of N-4-Methoxybenzoyl-N’-(4-Fluorophenyl)Thiourea On Hela Cell Line, Anindi Lupita Nasyanka
The Thai Journal of Pharmaceutical Sciences
Tiourea derivatives such as phenylthiourea, benzoyltiourea, tenovin, and many more have been reported as anticancer agent. In this study, we have done some initial step (docking, synthesis, and cytotoxic assay) to develop one of thiourea derivatives, N-4.
Enhancement Of Solubility And Dissolution Rate Of Quercetin With Solid Dispersion System Formation Using Hpmc Matrix, Dwi Setyawan
Enhancement Of Solubility And Dissolution Rate Of Quercetin With Solid Dispersion System Formation Using Hpmc Matrix, Dwi Setyawan
The Thai Journal of Pharmaceutical Sciences
Purpose : The aim of the present study was to obtain raw quercetin materials using solid dispersion system with better solubility and dissolution rate than pure quercetin. Methods: The solid dispersion of Quercetin-HPMC was prepared by solvent method. Su.
Gold Nanoparticle-Colocasia Gigantean Conjugates For Enhancing Cytotoxic Effect Against A375 Melanoma Cell Line, Amornpun Sereemaspun
Gold Nanoparticle-Colocasia Gigantean Conjugates For Enhancing Cytotoxic Effect Against A375 Melanoma Cell Line, Amornpun Sereemaspun
The Thai Journal of Pharmaceutical Sciences
Herbs are a prototype of traditional medicine for primary health care. Their knowledge is the basis of many modern medicinal discoveries. With the new invention of nanomaterials for biomedical applications, gold nanoparticles (AuNPs) have been proven to .
Determination Of Ethionamide In Pharmaceutical By Spectrophotometry Via Oxidation Reaction With Potassium Iodate, Nagib A.S. Qarah, Kanakapura Basavaiah
Determination Of Ethionamide In Pharmaceutical By Spectrophotometry Via Oxidation Reaction With Potassium Iodate, Nagib A.S. Qarah, Kanakapura Basavaiah
The Thai Journal of Pharmaceutical Sciences
Two new spectrophotometric methods are described for the determination of ethionamide (ETM) in pure and tablet forms. Method A is based on the oxidation of ETM by KIO3 in H2SO4 medium, and the in situ generated iodine is extracted into chloroform and mea.
In Vitro Antimicrobial Activity Of Antidesma Bunius Extracts On Oral Pathogenic Bacteria, Panicha Pongnaratorn, Prakasit Kuacharan, Vayura Kotsuno, Naruwat Pakdee, Pranee Sriraj, Jintana Sattayasai
In Vitro Antimicrobial Activity Of Antidesma Bunius Extracts On Oral Pathogenic Bacteria, Panicha Pongnaratorn, Prakasit Kuacharan, Vayura Kotsuno, Naruwat Pakdee, Pranee Sriraj, Jintana Sattayasai
The Thai Journal of Pharmaceutical Sciences
High antioxidant content of Antidesma bunius may lead to many beneficial pharmaceutical properties such as an anti-bacterial, anti-inflammatory and somatic cell decelerations, as well as cancer prevention. This study aimed at quantifying total phenolic c.
Analytical Method Development And Validation For Iron And Ascorbic Acid In Ferrous Bisglyciante Effervescent Tablets By Colorimetry And Rp-Hplc., Vasantharaju Sg
Analytical Method Development And Validation For Iron And Ascorbic Acid In Ferrous Bisglyciante Effervescent Tablets By Colorimetry And Rp-Hplc., Vasantharaju Sg
The Thai Journal of Pharmaceutical Sciences
A sensitive colorimetric and reverse phase high performance liquid chromatographic method was developed for estimation of total iron and ascorbic acid in ferrous bisglycinate effervescent tablets. A colorimetric method was developed for total iron us...
The Reform Of Drug Patent System In Thailand, Wanna Sriviriyanupap
The Reform Of Drug Patent System In Thailand, Wanna Sriviriyanupap
The Thai Journal of Pharmaceutical Sciences
Drug patent system has a direct impact on the health care cost and the access of the drugs of people. Previously, the drug patent system in Thailand encounters the problems both efficiency and quality of patent approval. This study aims to analyze the pr.