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Articles 151 - 180 of 1530
Full-Text Articles in Pharmacology
Non-Destructive Analysis Of Glycyrrhizin In Ummaruekvati Dispensatory Thai Traditional Medicine, Thanattaporn Charoenkittrakul, Chanamate Noi-Ang, Prathan Luecha, Jomjai Peerapattana
Non-Destructive Analysis Of Glycyrrhizin In Ummaruekvati Dispensatory Thai Traditional Medicine, Thanattaporn Charoenkittrakul, Chanamate Noi-Ang, Prathan Luecha, Jomjai Peerapattana
The Thai Journal of Pharmaceutical Sciences
Ummaruekvati is an antitussive traditional medicine. It contains licorice as the main ingredient and the major chemical component is glycyrrhizin. The conventional method for quantitative analysis of glycyrrhizin content in licorice is by high-performance liquid chromatography, which is destructive of the sample, time consuming, high cost, and has many steps in the sample preparation process. In this study, a rapid and non-destructive near-infrared spectroscopy (NIR) method was applied for quantitative analysis of glycyrrhizin content in Ummaruekvati dispensatories. A partial least squares chemometric method with various data pre-treatments was performed to establish the calibration model. The best calibration model was obtained …
Monitoring Of Crystalline Transition During Wet Granulation Process Using Probe Type Low Frequency Raman Spectrometer, Kanako Fukui, Yota Suzuki, Kazuki Haneishi, Varin Titapiwatanakun, Hiroshi Hisada, Tatsuo Koide, Toshiro Fukami
Monitoring Of Crystalline Transition During Wet Granulation Process Using Probe Type Low Frequency Raman Spectrometer, Kanako Fukui, Yota Suzuki, Kazuki Haneishi, Varin Titapiwatanakun, Hiroshi Hisada, Tatsuo Koide, Toshiro Fukami
The Thai Journal of Pharmaceutical Sciences
In recent years, real time analysis has been widely studied using various Process Analytical Technology tools particularly in the quality control of drug products. In this study, we investigated the improvement of sensitivity and the reduction of measurement time using a low frequency (LF) Raman spectrometer equipped with a new light source for in situ monitoring of crystalline transformation of active pharmaceutical ingredients (API) during wet granulation process. Three model drugs were chosen to assess the system sensitivity, hydrate transition, and cocrystal dissociation. LF Raman spectra showed the specific peaks for crystalline indomethacin and theophylline which were typical and well …
In-Line Prediction Of Secondary Drying Time From Measured Ice Nucleation Temperature During Lyophilization Process, Tharavich Supakatisant, Narueporn Sutanthavibul, Oran Kittithreerapronchai
In-Line Prediction Of Secondary Drying Time From Measured Ice Nucleation Temperature During Lyophilization Process, Tharavich Supakatisant, Narueporn Sutanthavibul, Oran Kittithreerapronchai
The Thai Journal of Pharmaceutical Sciences
Purpose: To propose an approach to find optimal secondary drying time (tSD) specifically for each lyophilized batch by predicting residual moisture at the beginning of secondary drying (Cs0) using measured ice nucleation temperatures (TN) obtained in-line. Materials and Methods: Value of Cs0 was determined by minimizing the residual error between measured (Tp SD,mea) and calculated (Tp SD,cal) product temperatures during secondary drying. Value of TN was determined by using product temperatures during freezing (TP Fr). Then, the correlation between Cs0 and TN was conducted and resulted in the Cs0 prediction equation. This equation was used with developed mathematical simulation to …
Inhibition Of Viper Venom-Induced Toxicity By Moringa Oleifera Leaves Extracts, Asha B. Thomas, Snehal Karanjkhele, Nitin Salvi, Lata Kothapalli, Aaftab Shaikh, Seema Kamble
Inhibition Of Viper Venom-Induced Toxicity By Moringa Oleifera Leaves Extracts, Asha B. Thomas, Snehal Karanjkhele, Nitin Salvi, Lata Kothapalli, Aaftab Shaikh, Seema Kamble
The Thai Journal of Pharmaceutical Sciences
Snakebite, a medical emergency, is a socially significant but neglected issue in India. Antivenom serum therapy that is currently used against venomous snakebites is expensive and showed severe side effects. Traditional claims reported the use of Moringa oleifera to treat snakebite in rural India. To scientifically validate these claims, in the present investigation, the antivenom potential of the extracts of M. oleifera was investigated. The extracts effectively neutralized Russell’s viper venom-induced lethality (LD50: 10.9 μg) at 10 μg/mice and 300 μg/mice (ED50), respectively. Both extracts neutralized venom-induced hemolysis (50–100 μg). Inhibitory concentrations against phospholipase A2 activity exhibited by aqueous and …
Probable Selective Compounds For Inhibition Of Sars-Cov-2 Infection: A Review, Nagaraju Rajendraprasad
Probable Selective Compounds For Inhibition Of Sars-Cov-2 Infection: A Review, Nagaraju Rajendraprasad
The Thai Journal of Pharmaceutical Sciences
The world is severely facing the pandemic COVID-19 Corona viral disease. Many people died and more than five millions are fighting for their life in the world. The viral candidate has become to play villain role for the real life due to non-availability of medication. In this background attempt is made to present a review report on the probable and effective compounds to inhibit the viral activity of SARS-CoV-2. The works on the use of plant-based and synthetic compounds to suppress the viral functioning is summarized. Wherever possible, the mechanism of action with the results and effect of dose are …
Development And Validation Of High- Performance Liquid Chromatography Method For Estimation Of Seratrodast In Spiked Human Plasma, Sandeep S. Sonawane, Priyanka T. Shinde, Gayatri S. Joshi, Sanjay J. Kshirsagar
Development And Validation Of High- Performance Liquid Chromatography Method For Estimation Of Seratrodast In Spiked Human Plasma, Sandeep S. Sonawane, Priyanka T. Shinde, Gayatri S. Joshi, Sanjay J. Kshirsagar
The Thai Journal of Pharmaceutical Sciences
In the work presented, an high-performance liquid chromatography method was developed and validated for the estimation of seratrodast (SER) in spiked human plasma, using flurbiprofen as an internal standard (IS). The drug and IS were extracted from pooled human plasma sample using 5 mL of tert-butyl methyl ether with 200 μL of 1% v/v formic acid. Both SER and IS were well separated and resolved from each other and plasma interferents using 20 mM phosphate buffer (pH 3.0) with acetonitrile in the proportion of 30: 70% v/v, in an isocratic mode at 1 mL/min on a C18 column and detection …
Moss Bryum Weigelii Spreng Improves Survival In Septic Rats Induced By Cecal Ligation And Puncture, Ho Viet Hieu, Surendra Babu Lagu, Vinay Bharadwaj Tatipamula
Moss Bryum Weigelii Spreng Improves Survival In Septic Rats Induced By Cecal Ligation And Puncture, Ho Viet Hieu, Surendra Babu Lagu, Vinay Bharadwaj Tatipamula
The Thai Journal of Pharmaceutical Sciences
The present study investigated the phytochemical, high-performance thin-layer chromatography (HPTLC) profiling, total phenolic content, antibacterial activity, acute toxicity studies, hemodynamic parameters, myeloperoxidase (MPO) activity and serum procalcitonin (PCT) levels of hydroalcoholic extract of Bryum weigelii (HE-Bw), and its effects on cecal ligation and puncture (CLP) induced sepsis in mice. The preliminary phytochemical screening showed that HE-Bw contains alkaloids, terpenoids, flavonoids, phenolics, and tannins. The HPTLC analysis of HE-Bw identified three unknown components with different Rf values and area percentage. The total phenolic amount for HE-Bw was equivalent to 211.6 ± 0.8 mg of gallic acid per 100 g of dried …
Treatment Outcomes And Their Predictive Factors In Patients Withenterobacter Spp., Serratia Spp.,Citrobacter Spp., Providencia Spp., I-Indole-Positive Proteus Spp., Andmorganella Spp, Bloodstream Infection, Wichai Santimaleeworagun, Dhitiwat Changpradub, Sudaluck Thunyaharn, Piraporn Juntanawiwat, Patsachon Kungsahadhum6, Phornusa Leartamornsakulchai, Waramporn Seubsai, Pratewee Satavetin
Treatment Outcomes And Their Predictive Factors In Patients Withenterobacter Spp., Serratia Spp.,Citrobacter Spp., Providencia Spp., I-Indole-Positive Proteus Spp., Andmorganella Spp, Bloodstream Infection, Wichai Santimaleeworagun, Dhitiwat Changpradub, Sudaluck Thunyaharn, Piraporn Juntanawiwat, Patsachon Kungsahadhum6, Phornusa Leartamornsakulchai, Waramporn Seubsai, Pratewee Satavetin
The Thai Journal of Pharmaceutical Sciences
The present study examined the treatment outcomes and factors related to mortality in patients with Enterobacter spp., Serratia spp., Citrobacter spp., Providencia spp., I-indole-positive Proteus spp., and Morganella spp. (ESCPIM) bloodstream infections and determined the susceptibility of ESCPIM pathogens to antimicrobial compounds. This retrospective study was performed at a university hospital in Thailand, using records from March 2017 to December 2018. Fifty-six patients with ESCPIM bacteremia were included. Approximately, half the patient cohort (55.4%) was infected with Enterobacter spp. The in-hospital mortality rate was 23.2%. Of the 56 patients studied, 20 patients (35.7%) had received a carbapenem treatment regimen, whereas …
In Vitro And In Vivo Effects Of Zanthoxylum Limonella (Dennst.) Alston. Crude Extracts And Volatile Oil On Blood Glucose Reduction, Attarat Pattanawongsa, Chaweewan Klongsiriwet, Peerarat Thaina, Aunchalee Prammano, Nattaphop Maneechai, Phitchapha Saengphrom, Gorawit Yusakul, Maleeruk Utsintong
In Vitro And In Vivo Effects Of Zanthoxylum Limonella (Dennst.) Alston. Crude Extracts And Volatile Oil On Blood Glucose Reduction, Attarat Pattanawongsa, Chaweewan Klongsiriwet, Peerarat Thaina, Aunchalee Prammano, Nattaphop Maneechai, Phitchapha Saengphrom, Gorawit Yusakul, Maleeruk Utsintong
The Thai Journal of Pharmaceutical Sciences
Introduction: Complimentary medicines have been long investigated as new and alternative therapeutic options for treating type 2 diabetes mellitus because the current drugs are associated with adverse drug reactions. The antidiabetic potential of the Zanthoxylum genus has been demonstrated previously. However, Zanthoxylum limonella (Dennst.) (ZL) has not been evaluated in any clinical trials. Objectives: This study aimed to examine the inhibition of α-glucosidases in vitro and in vivo using ZL fruit extracts, thereby determining the reduction in blood glucose levels using oral glucose and sucrose tolerance tests. Results and Discussion: The water extract of ZL fruits showed the greatest inhibition …
Simultaneous Estimation Of Ivacaftor And Tezacaftor In Rat Plasma By Liquid Chromatography Coupled With Tandem-Mass-Spectrometry: Application To Pharmacokinetic Studies, M. Satya Venkata, A. Lakshmana Rao, M. William Carey
Simultaneous Estimation Of Ivacaftor And Tezacaftor In Rat Plasma By Liquid Chromatography Coupled With Tandem-Mass-Spectrometry: Application To Pharmacokinetic Studies, M. Satya Venkata, A. Lakshmana Rao, M. William Carey
The Thai Journal of Pharmaceutical Sciences
Background: Ivacaftor and Tezacaftor belong to the CFTR potentiator class, in combination approved to manage cystic fibrosis. Objective: To establish a sensitive LC-MS/MS approach for the synchronized analysis of Ivacaftor and Tezacaftor and its appliance to rat pharmacokinetic investigation. Methodology: Method is developed with protein precipitation by acetonitrile and Ivacaftor-d4, Tezacaftor-d4 are used as internal standards. Separation is done on an Eclipse plus C18 analysis column (100 mm × 4.6 mm 1.8 μm) with a mobile phase consisting of 0.1% trifluoroacetic acid: acetonitrile (ratio 60:40, v/v, and pH 2.5) and flow stream of 1.0 mL/min at ambient temperature. Results: The …
Gas Chromatography-Flame Ionization Detector Analysis Of Amb-Fubinaca From Criminal Evidences In Vietnam, Anh Tuan Nguyen, Dang Tien Nguyen, Duy Toan Pham
Gas Chromatography-Flame Ionization Detector Analysis Of Amb-Fubinaca From Criminal Evidences In Vietnam, Anh Tuan Nguyen, Dang Tien Nguyen, Duy Toan Pham
The Thai Journal of Pharmaceutical Sciences
Synthetic cannabinoids are currently the largest group of new psychoactive substances. Among them, one of the most recent compounds in Vietnam is AMB-Fubinaca. No quantitative method has been officially implied for AMB-Fubinaca in criminal evidences, thus, making the police investigations burdensome. This study, for the 1st time, aimed to develop and validate the gas chromatography with flame ionization detector (GC-FID) method to determine and quantify AMB-Fubinaca in criminal evidences found in the South of Vietnam from 2016 to 2018. Chromatography separation was achieved on diphenyl dimethyl polysiloxane GC column (30 m × 0.32 mm × 0.25 μm) with a total …
Effect Of The Hydrophilic-Lipophilic Balance Values Of Non-Ionic Surfactants On Size And Size Distribution And Stability Of Oil/Water Soybean Oil Nanoemulsions, Kamonwan Singpanna, Dusadee Charnvanich
Effect Of The Hydrophilic-Lipophilic Balance Values Of Non-Ionic Surfactants On Size And Size Distribution And Stability Of Oil/Water Soybean Oil Nanoemulsions, Kamonwan Singpanna, Dusadee Charnvanich
The Thai Journal of Pharmaceutical Sciences
Objective: This study aims at investigating the effect of the hydrophilic-lipophilic balance (HLB) of non-ionic surfactants on physical property and stability of nanoemulsions. Materials and Methods: The nanoemulsions were prepared using the Microfluidizer. The oil phase consisted of 10% w/w soybean oil and 5% w/w surfactant(s). Types of nanoemulsions were confirmed by dilution test. The average droplet size and size distribution (polydispersity index [PDI]) were measured by dynamic light scattering Zetasizer Nano ZS™. The screening physical stability was done by centrifugation. Only the formulations with no phase separation were further evaluated for physical stability. Results: All nanoemulsions were single phase …
Systematic Development By The Design-Of-Experiment Approach And Physicochemical Evaluations Of The Optimized Self-Microemulsifying Astaxanthin Delivery System, Mo Mo Ko Zin, Veerakiet Boonkanokwong
Systematic Development By The Design-Of-Experiment Approach And Physicochemical Evaluations Of The Optimized Self-Microemulsifying Astaxanthin Delivery System, Mo Mo Ko Zin, Veerakiet Boonkanokwong
The Thai Journal of Pharmaceutical Sciences
A self-microemulsifying delivery system (SMEDS) containing astaxanthin (AST) was developed and optimized using a mixture design and its desirability function. Independent factors studied in the experimental design were the amounts of castor oil, Cremophor® RH 40, and Tween® 80 in a formula. The measured response variables included droplet size, polydispersity index (PDI), zeta potential, active ingredient content, and transmittance of microemulsions obtained from the AST SMEDS formulations. The desirability function was then adjusted to optimize the formulation. The optimized AST SMEDS was composted of 19.59% castor oil, 62.34% Cremophor® RH 40, and 18.03% Tween® 80, and the resulting self microemulsions …
Antiplasmodial Activity Of Hyptis Pectinata Extract And Its Analog Against 3d7 Plasmodium Falciparum Through Caseinolytic Protease Proteolytic (Clpp) Inhibition, Meiny Suzery, Bambang Cahyono, Nur Dina Amalina, Cahyo Budiman, Ibnu Bayu, Mukhammad Asy’Ari, Widayat
Antiplasmodial Activity Of Hyptis Pectinata Extract And Its Analog Against 3d7 Plasmodium Falciparum Through Caseinolytic Protease Proteolytic (Clpp) Inhibition, Meiny Suzery, Bambang Cahyono, Nur Dina Amalina, Cahyo Budiman, Ibnu Bayu, Mukhammad Asy’Ari, Widayat
The Thai Journal of Pharmaceutical Sciences
Hyptolide and epoxy hyptolide were successfully isolated and synthesized from Hyptis pectinata extract that potential to cure malaria diseases. The previous studies showed that these compounds contained lactone groups associated with antibacterial and anticancer activities. However, the antimalarial activity remained unclear. This study aimed to investigate the antiplasmodial activity of H. pectinata extract, hyptolide, and epoxy hyptolide. These compounds were tested in vitro for antiplasmodial activity against chloroquinesensitive 3D7 strain of Plasmodium falciparum. Thin blood smears were used to assess the levels of parasitemia and growth inhibition of the isolates and the ClpP inhibition was analyzed under well diffusion assay. …
Development Of Health-Related Quality Of Life Questionnaire For Patients On Continuous Drug Use, Wanna Tangpakdeerat, Rungpetch Sakulbumrungsil
Development Of Health-Related Quality Of Life Questionnaire For Patients On Continuous Drug Use, Wanna Tangpakdeerat, Rungpetch Sakulbumrungsil
The Thai Journal of Pharmaceutical Sciences
Background: Health-Related Quality of Life (HRQoL) instruments has become as a principal indicator of the effectiveness of medication treatment especially in case of lifelong therapy. Objectives: The purposes of the study were to develop a quality of lif.
Cell Viability Enhancing And Cellular Protection Activity Of Vitex Glabrata R.Br. Crude Fruits Extract On Tk6 And L929 Cell Lines, Saraphorn Intarasam, Thatchaphon Meemin, Mesayamas Kongsema, Kantimanee Pradermwong
Cell Viability Enhancing And Cellular Protection Activity Of Vitex Glabrata R.Br. Crude Fruits Extract On Tk6 And L929 Cell Lines, Saraphorn Intarasam, Thatchaphon Meemin, Mesayamas Kongsema, Kantimanee Pradermwong
The Thai Journal of Pharmaceutical Sciences
Studying the plant-based traditional medicine is a starting point for the advancement of modern studies. Vitex glabrata (VG) or Khai-Noa is a medicinal plant in Thailand, which fruits have been used by Thai ancients to improve cognition and enhance memor.
Spectrophotometric Estimation Of Linagliptin Using Ion-Pair Complexation And Oxidative Coupling Reactions – A Green Approach, Sunitha Gurrala, Panikumar Durga Anumolu, Sahitya Menkana, Nikitha Gandla, Keerthi Toddi
Spectrophotometric Estimation Of Linagliptin Using Ion-Pair Complexation And Oxidative Coupling Reactions – A Green Approach, Sunitha Gurrala, Panikumar Durga Anumolu, Sahitya Menkana, Nikitha Gandla, Keerthi Toddi
The Thai Journal of Pharmaceutical Sciences
Background: Two specific spectrophotometric methods (visible region) have been established using water as a solvent and validated for the analysis of linagliptin in API and pharmaceutical dosage forms. Materials and Methods: Method-A is established on th.
Pharmacy Workforce In Myanmar Public Sector, Lwin Nyein Aye, Puree Anantachoti
Pharmacy Workforce In Myanmar Public Sector, Lwin Nyein Aye, Puree Anantachoti
The Thai Journal of Pharmaceutical Sciences
Objective: Pharmacist shortage in Myanmar was recognized, but previous local study was unavailable. This study aimed to analyze Myanmar’s pharmacist workforce situation focusing on public sector. Materials and Methods: Mixed method combining secondary ...
Poly(Lactic-Co-Glycolic Acid) - Polyethylene Glycol Copolymer For Long-Acting Injectable: Synthesis, Characterization, And In-Vivo Study, Ravindra Kamble, Manasi Kulkarni, Swati Korake, Abhishek Pawar, Krishnat Dhekale
Poly(Lactic-Co-Glycolic Acid) - Polyethylene Glycol Copolymer For Long-Acting Injectable: Synthesis, Characterization, And In-Vivo Study, Ravindra Kamble, Manasi Kulkarni, Swati Korake, Abhishek Pawar, Krishnat Dhekale
The Thai Journal of Pharmaceutical Sciences
Aim: This work was aimed to develop a carrier system of poly(lactic-co-glycolic acid) (PLGA) by using polyethylene glycol (PEG) for longer action in various diseases by preparing a di-block copolymer by using Risperidone (RSP) as a drug. Methodology: PLG.
Measuring The Potential Antioxidant Activity Of Methyl Gallate: Molecular Docking Study, Sutomo S, Mohammad Rizki Fadhil Pratama
Measuring The Potential Antioxidant Activity Of Methyl Gallate: Molecular Docking Study, Sutomo S, Mohammad Rizki Fadhil Pratama
The Thai Journal of Pharmaceutical Sciences
Objectives: This study aims to obtain predictions of the interactions that occur between methyl gallate and various antioxidant receptors while comparing it with gallic acid as its parent compound. Materials and Methods: The protein crystal structures of.
Assessment Of Antimicrobial Activity Of Moxifloxacin.Hcl From Gastro Retentive Formulations, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
Assessment Of Antimicrobial Activity Of Moxifloxacin.Hcl From Gastro Retentive Formulations, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
The Thai Journal of Pharmaceutical Sciences
Purpose: The objective of the present study is to assess the antimicrobial activity of gastroretentive formulation for moxifloxacin HCl and in vitro antimicrobial evaluation using the cup-plate method. Materials and Methods: Gastroretentive floating tabl.
Development And Validation Of Rp-Hplc Method For Simultaneous Determination Of Ondansetron Hydrochloride And Granisetron Hydrochloride In Their Admixtures With Pantoprazole Sodium, Al Montaser Hamed Bellah, Abdel Maaboud Ismail Mohamed, Niveen Abdel-Latif Mohamed
Development And Validation Of Rp-Hplc Method For Simultaneous Determination Of Ondansetron Hydrochloride And Granisetron Hydrochloride In Their Admixtures With Pantoprazole Sodium, Al Montaser Hamed Bellah, Abdel Maaboud Ismail Mohamed, Niveen Abdel-Latif Mohamed
The Thai Journal of Pharmaceutical Sciences
Objective: Development of rapid and sensitive high-performance liquid chromatography method for the quantification of ondansetron hydrochloride and granisetron hydrochloride in their admixtures with pantoprazole sodium in its dosage form using ketorolac .
The Effects Of Ball Mill Processing On The Physicochemical Properties Of Glutinous Rice Starch, Weeraya Tharanon, Jomjai Peerapattana
The Effects Of Ball Mill Processing On The Physicochemical Properties Of Glutinous Rice Starch, Weeraya Tharanon, Jomjai Peerapattana
The Thai Journal of Pharmaceutical Sciences
Glutinous rice starch (GRS) (Oryza sativa L.) is a product derived from a staple food that is commonly cultivated and consumed in Asia. This study investigates the effect of physical modification by planetary ball mill processing on some physicochemical .
Anti-Tyrosinase And Anti-Melanogenic Potential Of Shallots (Allium Ascalonicum) From Various Cultivation Sites In Thailand, Thidarat Phetmanee, Thaniya Wunnakup, Thitiya Lukkunaprasit, Fameera Madaka, Sukanya Settharaksa, Narisa Kamkaen, Nirun Vipunnqeun, Laksana Charoenchai
Anti-Tyrosinase And Anti-Melanogenic Potential Of Shallots (Allium Ascalonicum) From Various Cultivation Sites In Thailand, Thidarat Phetmanee, Thaniya Wunnakup, Thitiya Lukkunaprasit, Fameera Madaka, Sukanya Settharaksa, Narisa Kamkaen, Nirun Vipunnqeun, Laksana Charoenchai
The Thai Journal of Pharmaceutical Sciences
Objectives: The present study aimed to investigate the anti-tyrosinase effect of shallots (Allium ascalonicum) in Thailand and to prepare an optimised shallot extract for use as a skin-lightening agent. Materials and Methods: Aqueous and ethanolic shallo.
In Silico Discovery Of Potential Diagnostic Biomarkers Of Lung Cancer, Ruzianisra Mohamed, Raja Nur Hidayah Raja Hasnan
In Silico Discovery Of Potential Diagnostic Biomarkers Of Lung Cancer, Ruzianisra Mohamed, Raja Nur Hidayah Raja Hasnan
The Thai Journal of Pharmaceutical Sciences
Introduction: Understanding hub genes implicated in lung cancer (LC) metastasis will help in finding effective ways to diagnose and cure cancer. Accurate identification of protein biomarkers helps in improving the prognosis of LC. Here, the focus of this.
Progress In Erectile Dysfunction Therapy Through Drug Delivery System, Mayuri Shitole, Shailesh Dugam, Rahul Tade, Neha Desai, Sopan Nangare
Progress In Erectile Dysfunction Therapy Through Drug Delivery System, Mayuri Shitole, Shailesh Dugam, Rahul Tade, Neha Desai, Sopan Nangare
The Thai Journal of Pharmaceutical Sciences
A man’s aptitude to acquire and continue an erection is frequently equated with masculinity and virility and can greatly influence men’s confidence. The sexual healthiness is a significant determinant of the worth of life. Erectile dysfunction (ED) a...
In Silico Screening Of Natural Compounds To Identify Lead As Interleukin 17a Receptor Blockers As Antihypertensive Agents, Jimish R. Patel, Hirak V. Joshi, Ujashkumar A. Shah, Jayvadan K. Patel
In Silico Screening Of Natural Compounds To Identify Lead As Interleukin 17a Receptor Blockers As Antihypertensive Agents, Jimish R. Patel, Hirak V. Joshi, Ujashkumar A. Shah, Jayvadan K. Patel
The Thai Journal of Pharmaceutical Sciences
Objectives: Nature gives disease and nature gives the medicine. Natural products have exhibited paramount sources of novel drugs. Due to this, natural products have gained a dominant role in drug design and discovery. Interleukin 17 (IL-17) is a potent p.
Chemical Composition Of The Essential Oil Of Several Iris Species, Olha Mykhailenko N/A, Volodymyr Kovalyov, Tetyana Orlova
Chemical Composition Of The Essential Oil Of Several Iris Species, Olha Mykhailenko N/A, Volodymyr Kovalyov, Tetyana Orlova
The Thai Journal of Pharmaceutical Sciences
The essential oil was obtained by a steam distillation from the dried leaves of Iris germanica L., Iris versicolor L., Iris graminea L., and Iris halophila Pall. (Iridaceae) and was investigated by a gas chromatography-mass spectrometry (GC/MS) method. I.
Anthelmintic Activity Of Mansoa Alliacea Against Pheretima Posthuma: In Vitro And In Silico Approach, D.S. N. B. K. Prasanth, S. K. Aminabee, Atmakuri Lakshmana Rao, Nayudu Teja, Koti Bhargavi, Chigurupati Monika, Boppudi Pujitha, Tera Sandhya, Agastya Lalitha, Siva Prasad Panda
Anthelmintic Activity Of Mansoa Alliacea Against Pheretima Posthuma: In Vitro And In Silico Approach, D.S. N. B. K. Prasanth, S. K. Aminabee, Atmakuri Lakshmana Rao, Nayudu Teja, Koti Bhargavi, Chigurupati Monika, Boppudi Pujitha, Tera Sandhya, Agastya Lalitha, Siva Prasad Panda
The Thai Journal of Pharmaceutical Sciences
Objectives: Mansoa alliacea has been utilized to remedy many afflictions of humans. Literary works illustrate that it possesses numerous biological activities. Our analysis work aims to distinguish phyto-derived anthelmintic substances from M. alliacea a.
Conditioned Medium Of Lipopolysaccharide-Treated Embryonic Stem Cell-Derived Mesenchymal Stem Cells Modulates In Vitro Secretion Of Inflammatory Cytokines, Faezeh Maghsood, Behrooz Johari, Nastaran Mohammadi Ghahhari, Mohammad Moradi, Mehdi Kadivar
Conditioned Medium Of Lipopolysaccharide-Treated Embryonic Stem Cell-Derived Mesenchymal Stem Cells Modulates In Vitro Secretion Of Inflammatory Cytokines, Faezeh Maghsood, Behrooz Johari, Nastaran Mohammadi Ghahhari, Mohammad Moradi, Mehdi Kadivar
The Thai Journal of Pharmaceutical Sciences
Background: The immunomodulatory properties of mesenchymal stem cells (MSCs) secretome have been considered by many investigators, and several preconditioning strategies such as pharmaceutical preconditioning have shown to strengthen the immunomodulatory.