Open Access. Powered by Scholars. Published by Universities.®
Medicinal Chemistry and Pharmaceutics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (12)
- Pharmacology (10)
- Chemicals and Drugs (7)
- Diseases (5)
- Parasitic Diseases (4)
-
- Biology (3)
- Medicinal and Pharmaceutical Chemistry (3)
- Pharmaceutics and Drug Design (3)
- Pharmacy and Pharmaceutical Sciences (3)
- Plant Sciences (3)
- Alternative and Complementary Medicine (2)
- Bacteriology (2)
- Biochemistry (2)
- Biochemistry, Biophysics, and Structural Biology (2)
- Biotechnology (2)
- Chemical Actions and Uses (2)
- Chemistry (2)
- Enzymes and Coenzymes (2)
- Genetics and Genomics (2)
- Heterocyclic Compounds (2)
- Medical Sciences (2)
- Microbiology (2)
- Natural Products Chemistry and Pharmacognosy (2)
- Organic Chemicals (2)
- Physical Sciences and Mathematics (2)
- Social and Behavioral Sciences (2)
- Agricultural Science (1)
- Institution
-
- Wayne State University (9)
- Dominican University of California (4)
- Virginia Commonwealth University (4)
- Purdue University (2)
- University of Kentucky (2)
-
- Andrews University (1)
- Antioch University (1)
- California Polytechnic State University, San Luis Obispo (1)
- Montclair State University (1)
- The Texas Medical Center Library (1)
- The University of Southern Mississippi (1)
- University of Arkansas, Fayetteville (1)
- University of Connecticut (1)
- University of Nebraska - Lincoln (1)
- University of Nebraska Medical Center (1)
- University of Rhode Island (1)
- Keyword
-
- Malaria (2)
- Plasmodium falciparum (2)
- 3D Graphics model (1)
- Activity-based (1)
- Aerodynamic particle size distribution (1)
-
- Anticholinesterase agent (1)
- Antiemetic (1)
- Antineoplastic agents (1)
- Antiparasitic agents (1)
- Antitumor Drug (1)
- Aquaculture (1)
- Artemisinin (1)
- Artemisinin Resistance (1)
- Behavior (1)
- Belo Horizonte (1)
- Bioethanol (1)
- Blue-green algae (1)
- Brazil (1)
- Cellulase (1)
- Chemical space (1)
- Cholesterol (1)
- Clozapine (1)
- Conditioned avoidance response (1)
- Contextual theory (1)
- Corn (1)
- Cytotoxic Agents (1)
- DNA sequencing (1)
- Daphnia (1)
- Double-blind (1)
- Drug dependence (1)
- Publication
-
- Wayne State University Theses (8)
- Collected Faculty Scholarship (4)
- Theses and Dissertations (4)
- Antioch University Dissertations & Theses (1)
- Biological Sciences Faculty Publications and Presentations (1)
-
- Department of Justice Studies Faculty Scholarship and Creative Works (1)
- Department of Psychology: Faculty Publications (1)
- Dissertations and Theses (Open Access) (1)
- Doctoral Projects (1)
- Honors Scholar Theses (1)
- Honors Theses (1)
- Master's Theses (1)
- Open Access Dissertations (1)
- Senior Honors Projects (1)
- The Summer Undergraduate Research Fellowship (SURF) Symposium (1)
- Theses & Dissertations (1)
- Theses and Dissertations--Neuroscience (1)
- Theses and Dissertations--Pharmacy (1)
- Wayne State University Dissertations (1)
- Publication Type
Articles 31 - 32 of 32
Full-Text Articles in Medicinal Chemistry and Pharmaceutics
Islet Dysfunction In Diabetes, Syeda Khadija
Islet Dysfunction In Diabetes, Syeda Khadija
Wayne State University Dissertations
Type 2 Diabetes [T2DM] is a chronic condition resulting from gradual failure of pancreatic beta cells to synthesize and secrete sufficient insulin to meet the metabolic demands and the inability of tissues [muscle, adipose and liver] to efficiently utilize the secreted insulin leading to an overall increase in blood glucose levels [hyperglycemia]. As indicated by recent estimates from the International Diabetes Federation, the prevalence of the disease in the year 2014 has risen to a record 387 million worldwide. The main objective of my project was to study the mechanisms involved in pancreatic beta cell dysfunction in diabetes, specifically in …
Development Of Clinically Relevant In Vitro Performance Tests For Powder Inhalers, Xiangyin Wei
Development Of Clinically Relevant In Vitro Performance Tests For Powder Inhalers, Xiangyin Wei
Theses and Dissertations
While realistic in vitro testing of dry powder inhalers (DPIs) can be used to establish in vitro–in vivo correlations (IVIVCs) and predict in vivo lung doses, the aerodynamic particle size distributions (APSDs) of those doses and their regional lung deposition remains unclear. Four studies were designed to improve testing centered on the behavior of Novolizer®. Different oropharyngeal geometries were assessed by testing different mouth-throat (MT) models across a realistic range of inhalation profiles (IPs) with Salbulin® Novolizer®. Small and large Virginia Commonwealth University (VCU) and Oropharyngeal Consortium (OPC) models produced similar ranges for total lung dose in vitro (TLD …