Environmental Health Commons^™

Maternal Serum Polychlorinated Biphenyl Concentrations Across Critical Windows Of Human Development, Michael S. Bloom, Germaine M. Buck-Louis, Aiyi Liu

Environmental Health Sciences Faculty Scholarship

Background

Few data are available on polychlorinated biphenyl (PCB) concentrations over critical windows of human reproduction and development inclusive of the periconception window.

Objectives

Our goal was to measure changes in PCB concentrations from preconception to pregnancy, through pregnancy, or after a year without becoming pregnant.

Methods

Seventy-nine women planning pregnancies were prospectively enrolled and followed for up to 12 menstrual cycles of attempting pregnancy. Blood specimens were obtained from participating women preconceptionally (n = 79), after a positive pregnancy test leading to a live birth (n = 54) or pregnancy loss (n= 10), at approximately …

The Economics Of Water Utilization: Tools And Applications, Matt Bogard

Agriculture Department Seminar Series

Given worldwide problems of access to safe potable water, this presentation examines how tools of economics can aid in drafting appropriate mitigating policies. Utilizing partial equilibrium analysis, it demonstrates the role that prices play in social coordination and then applies the framework to real world examples. In addition it examines Pigouvian Taxation and Coasean Bargaining as two classic methods for dealing with externalities in the context of water pollution. Second-best solutions such as tradable permits and metered pricing by public utilities are discussed. This presentation concludes by examining the issues and challenges that policy makers face when trying to implement …

Biodosepr-2006 Consensus Committee Report On Biodosimetric Methods To Evaluate Radiation Doses At Long Times After Exposure, Steven L. Simon, Ian Bailiff, André Bouville, Paola Fattibene, Ruth A. Kleinerman, David C. Lloyd, Stephen W.S. Mckeever, Alexander Romanyukha, Alexander V, Sevan’Kaev, James D. Tucker, Albrecht Wieser

Uniformed Services University of the Health Sciences

The requirements for biodosimetric techniques used at long times after exposure, i.e., 6 months to more than 50 years, are unique compared to the requirements for methods used for immediate dose estimation. In addition to the fundamental requirement that the assay measures a physical or biologic change that is proportional to the energy absorbed, the signal must be highly stable over time to enable reasonably precise determinations of the absorbed dose decades later. The primary uses of these biodosimetric methods have been to support long-term health risk (epidemiologic) studies or to support compensation (damage) claims. For these reasons, the methods …

Healing Our Hazardous Environment, K V. Hall, B M. Afzal, Barbara Sattler

Nursing and Health Professions Faculty Research and Publications

No abstract provided.

Cell Cycle Analysis Of Atrazine-Treated Human Fibroblast Cells Using Flow Cytometry, Andrea L. Austin

Honors Program Theses

Atrazine is the most frequently used triazine herbicide in the United States. Studies have shown an association between herbicide exposure and increased levels of DNA damage, reproductive and endocrine problems, and an increased risk for certain cancers. The United States Environmental Protection Agency (USEP A) has set a maximum allowable limit at 3 parts per billion (ppb ). Previous work from our lab has shown decreased cell proliferation of normal human fibroblasts after low-level atrazine exposure for 72 hours at 0.8-100 ppb without a corresponding increase in apoptosis or necrosis.

The objective of the current study is to determine a …