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Articles 151 - 153 of 153
Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Sinusoidal Endothelial Cell-Derived Extracellular Matrix Regulates Basal And Stimulated Macrophage Activation., Lauren G. Poole
Sinusoidal Endothelial Cell-Derived Extracellular Matrix Regulates Basal And Stimulated Macrophage Activation., Lauren G. Poole
College of Arts & Sciences Senior Theses
Fatty liver disease, be it from alcohol (ALD), obesity (NAFLD) or other sources (e.g. viral infection), share similar mechanisms of disease progression. One potential mechanism is that altered sinusoidal endothelial cell (SEC) extracellular matrix (ECM) favors a more inflammatory phenotype in resident macrophages (i.e., Kupffer cells). Here, the hypothesis was tested that SEC-derived matrices directly affect the inflammatory response of macrophages. Methods. Transformed sinusoidal endothelial cells (TSECs) were cultured for 24 or 72 hours. Culture plates were then washed with a solution that selectively removed the cells, but preserved the ECM. Cultured macrophages (RAW 264.7 cells) were then seeded on …
Recent History Provides Sustainable African Water Quality Project Insight., Rochelle H. Holm
Recent History Provides Sustainable African Water Quality Project Insight., Rochelle H. Holm
Faculty and Staff Scholarship
Small-scale projects to provide clean drinking water undertaken in the developing world can contribute to significantly improving the livelihood of rural communities. There has been a historical tendency to poorly plan such projects leading to an unsustainable future. Recent history indicates three simple steps to ensuring successful and enduring clean water projects. First, identification of need by the indigenous community provides ownership in the project. Second, a partnership between key individuals in the indigenous community with the donor provides for ambassadors on both sides of the project. Finally, an exit strategy by the donors for the indigenous communities ensures local …
The Effect Of Drugs On Experimental Renal Hypertension In The Dog., J. J. Prusmack
The Effect Of Drugs On Experimental Renal Hypertension In The Dog., J. J. Prusmack
Electronic Theses and Dissertations
No abstract provided.