Human and Clinical Nutrition Commons^™

Ruminant Milk-Derived Extracellular Vesicles: A Nutritional And Therapeutic Opportunity?, Siew Ling Ong, Cherie Blenkiron, Stephen Haines, Alejandra Acevedo-Fani, Juliana A.S. Leite, Janos Zempleni, Rachel C. Anderson, Mark J. Mccann

Department of Nutrition and Health Sciences: Faculty Publications

Milk has been shown to contain a specific fraction of extracellular particles that are reported to resist digestion and are purposefully packaged with lipids, proteins, and nucleic acids to exert specific biological effects. These findings suggest that these particles may have a role in the quality of infant nutrition, particularly in the early phase of life when many of the foundations of an infant’s potential for health and overall wellness are established. However, much of the current research focuses on human or cow milk only, and there is a knowledge gap in how milk from other species, which may be …

Life Cycle Assessment Of Packaging Systems For Enteral Nutrition Products: Multilayer Pouch And High-Density Polyethylene Bottle, Martina Krueger, Benedikt Kauertz, Claudia Mayer

Journal of Applied Packaging Research

Environmental performance of alternative packaging options for a given product application increasingly comes into awareness, both at the end consumer level as well as in the field of business-to-business communication. The purpose of the study presented here is to examine the environmental performance of a multilayer pouch for packing of enteral nutrition products. To achieve this, a life cycle assessment has been conducted. As an attributional full cradle-to-grave life cycle assessment it compares environmental impacts of a comparable lighter multilayer pouch vs. two different comparable heavier high-density polyethylene bottles (covering the weight range of high-density polyethylene bottles on global markets …

Menu Engineering And Dietary Behavior Impact On Young Adults’ Kilocalorie Choice, Christine Bergman, Yuan Tian, Andrew Moreo, Carola Raab

Hospitality Faculty Research

The obesity pandemic is associated with increased consumption of restaurant food. Labeling of menus is an intervention used to provide consumers with kilocalorie (calorie) information in hopes of them making healthier food choices. This study evaluated the relationship between young adults’ calorie choices on restaurant menus and menu design, dietary behaviors, and demographic characteristics. A 3 (fast-casual restaurants) × 4 (menu-designs based on menu engineering theories) between-subjects (n = 480, 18–24-year olds) experimental design was used. The relationship between the participants’ calorie choices (high versus low) and menu design, stage of change, gender, race, educational level and weight status was …

Analysis Of Dietary Intake, Body Composition And Biomarkers In Adults With Type 2 Diabetes Mellitus, Prediabetes And Without Diabetes, Sarah Thuytrinh Nguyen

Master's Theses

Our study provided an analysis and comparison of specific blood values, dietary intake, body composition, and inflammatory markers (high sensitivity-C-reactive protein (HS-CRP), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6)) between adults with type 2 diabetes mellitus (T2DM) and prediabetes (PDM) to adults without diabetes. A total of 22 participants (PDM/T2DM n=12, controls n=10) in the San Luis Obispo, CA area completed the study prior to our ending recruitment due to Covid-19. Body composition data were collected through DXA scans. Dietary intake was assessed using a 3-day food record survey and nutritional analysis conducted using ESHA food processing software. In addition, …

Dfend Wrap Up, Jamie Baum, Erin Howie

Diet, Food, Exercise, and Nutrition (D-FEND)

This is an overview of DFEND from the beginning and what was learned and shared.

Carotenoid-Rich Brain Nutrient Pattern Is Positively Correlated With Higher Cognition And Lower Depression In The Oldest Old With No Dementia, Jirayu Tanprasertsuk, Tammy M. Scott, Aron K. Barbey, Kathryn Barger, Xiang-Dong Wang, Mary Ann Johnson, Leonard W. Poon, Rohini Vishwanathan, Nirupa R. Matthan, Alice H. Lichtenstein, Guylaine Ferland, Elizabeth R. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Background: Healthy dietary patterns are related to better cognitive health in aging populations. While levels of individual nutrients in neural tissues are individually associated with cognitive function, the investigation of nutrient patterns in human brain tissue has not been conducted.

Methods: Brain tissues were acquired from frontal and temporal cortices of 47 centenarians from the Georgia Centenarian Study. Fat-soluble nutrients (carotenoids, vitamins A, E, K, and fatty acids [FA]) were measured and averaged from the two brain regions. Nutrient patterns were constructed using principal component analysis. Cognitive composite scores were constructed from cognitive assessment from the time point closest to …

Summer Fun: Maintaining Healthy Behaviors When Schedules Change, Erin Howie, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Maintaining healthy behaviors during the summer and how best to take care of yourself in the heat.

Effect Of The Lysosomotropic Agent Chloroquine On Mtorc1 Activation And Protein Synthesis In Human Skeletal Muscle, Michael S. Borack, Jared M. Dickinson, Christopher S. Fry, Paul T. Reidy, Melissa M. Markofski, Rachel R. Deer, Kristofer Jennings, Elena Volpi, Blake B. Rasmussen

All Faculty Scholarship for the College of Education and Professional Studies

Background

Previous work in HEK-293 cells demonstrated the importance of amino acid-induced mTORC1 translocation to the lysosomal surface for stimulating mTORC1 kinase activity and protein synthesis. This study tested the conservation of this amino acid sensing mechanism in human skeletal muscle by treating subjects with chloroquine—a lysosomotropic agent that induces in vitro and in vivo lysosome dysfunction.

Methods

mTORC1 signaling and muscle protein synthesis (MPS) were determined in vivo in a randomized controlled trial of 14 subjects (10 M, 4 F; 26 ± 4 year) that ingested 10 g of essential amino acids (EAA) after receiving 750 mg of chloroquine …

What Role Does Stress Play In Overall Health?, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

What is Stress?

Alternative names for stress.

Types of stress.

Causes of stress.

Learning to recognize stress.

Impact Of Nutrition-Based Interventions On Athletic Performance During Menstrual Cycle Phases: A Review, Macy M. Helm, Graham R. Mcginnis, Arpita Basu

Kinesiology and Nutrition Sciences Faculty Research

Despite the steady increase in female participation in sport over the last two decades, comprehensive research on interventions attenuating the influence of female menstrual physiology on performance remains scarce. Studies involving eumenorrheic women often only test in one menstrual phase to limit sex hormone variance, which may restrict the application of these findings to the rest of the menstrual cycle. The impacts of nutrition-based interventions on athletic performance throughout the menstrual cycle have not been fully elucidated. We addressed this gap by conducting a focused critical review of clinical studies that reported athletic outcomes as well as menstrual status for …

The Age Of Artificial Intelligence: Use Of Digital Technology In Clinical Nutrition, Berkeley K. Limketkai, Kasuen Mauldin, Natalie Manitius, Laleh Jalilian, Bradley R. Salonen

Faculty Research, Scholarly, and Creative Activity

Purpose of review

Computing advances over the decades have catalyzed the pervasive integration of digital technology in the medical industry, now followed by similar applications for clinical nutrition. This review discusses the implementation of such technologies for nutrition, ranging from the use of mobile apps and wearable technologies to the development of decision support tools for parenteral nutrition and use of telehealth for remote assessment of nutrition.

Recent findings

Mobile applications and wearable technologies have provided opportunities for real-time collection of granular nutrition-related data. Machine learning has allowed for more complex analyses of the increasing volume of data collected. The …

What Is Self-Efficacy, Why Does It Matter, And How Can We Improve It?, Bryce Daniels

Diet, Food, Exercise, and Nutrition (D-FEND)

Self-efficacy defined and examples shared. Self-efficacy shows to directly influence health behavior performance.

Grit defined and examples shared. There are two components to grit: consistency of interest and perseverance of effort.

Palmitoleate Protects Against Zika Virus-Induced Placental Trophoblast Apoptosis, Philma Glora Muthuraj, Aryamav Pattnaik, Prakash K. Sahoo, Md Torikul Islam, Asit K. Pattnaik, Siddappa N. Byrareddy, Corrine K. Hanson, Ann Anderson Berry, Stephen D. Kachman, Sathish Kumar Natarajan

Department of Nutrition and Health Sciences: Faculty Publications

Zika virus (ZIKV) infection in pregnancy is associated with the development of microcephaly, intrauterine growth restriction, and ocular damage in the fetus. ZIKV infection of the placenta plays a crucial role in the vertical transmission from the maternal circulation to the fetus. Our previous study suggested that ZIKV induces endoplasmic reticulum (ER) stress and apoptosis of placental trophoblasts. Here, we showed that palmitoleate, an omega-7 monounsaturated fatty acid, prevents ZIKV-induced ER stress and apoptosis in placental trophoblasts. Human trophoblast cell lines (JEG-3 and JAR) and normal immortalized trophoblasts (HTR-8) were used. We observed that ZIKV infection of the trophoblasts resulted …

Implementing And Evaluating Health Behavior Changes, Robert E. Davis

Diet, Food, Exercise, and Nutrition (D-FEND)

Describes what health, health behavior and health behavior change mean and how to take action to create a health behavior change for yourself.

Vegetarian Diets, Maybe Not As Healthy As You Think, Darryl Goh, Debbie Chan, Merson Hoo, Ian Wong

Introduction to Research Methods RSCH 202

Many are approaching vegetarianism as a viable diet option in recent years, presuming that adopting a vegetarian diet would provide health benefits. This paper explores the possibilities of physical and mental effects that vegetarianism may have on humans and its extent by the use of regression analysis. To measure the possible impacts vegetarian diets may hold on both the physiology and physical aspects of humans, we have utilized the measures of life expectancy and prevalence of depression respectively. Cross-sectional data were examined from sources such as the World Health Organization, Our World In Data and the World Bank, with figures …

Communicating Healthy Behavior Choices In Your Community, Bonnie Faitak

Diet, Food, Exercise, and Nutrition (D-FEND)

How a team at UAMS has been helping communicate about healthy food choices across the region, state, and world.

How Do Food And Physical Activity Policies Affect Our Health?, Chris Long

Diet, Food, Exercise, and Nutrition (D-FEND)

Policy is generally defined and then tied into how food and physical health policies affect our everyday lives.

Mindful Eating And Perceived Stress In College Students, Emily G. Garrett

Graduate Theses

Background: Evidence suggests that in college student populations, stress levels often manifest as maladaptive eating and/or functional gastrointestinal disorders. These conditions can degrade wellbeing and academic performance if not addressed.

Research aim/question(s): The purpose of this study was to examine the relationships between students’ perceived stress, their overall mindfulness, and mindful eating patterns. Gastrointestinal (GI) symptoms and bowel habits were also investigated to determine whether these factors were stress-related or influenced mindfulness behaviors.

Materials and Methods: An online survey was conducted during the 2020-2021 academic year. Demographic information, including smoking, alcohol, and drug use patterns, was gathered in addition to …

An Intron Variant Of The Gli Family Zinc Finger 3 (Gli3) Gene Differentiates Resistance Training-Induced Muscle Fiber Hypertrophy In Younger Men, Christopher G. Vann, Robert W. Morton, Christopher B. Mobley, Ivan J. Vechetti, Brian K. Ferguson, Cody T. Haun, Shelby C. Osburn, Casey L. Sexton, Carlton D. Fox, Matthew A. Romero, Paul A. Roberson, Sara Y. Oikawa, Chris Mcglory, Kaelin C. Young, John J. Mccarthy, Stuart M. Phillips, Michael D. Roberts

Department of Nutrition and Health Sciences: Faculty Publications

We examined the association between genotype and resistance training-induced changes (12 wk) in dual x-ray energy absorptiometry (DXA)-derived lean soft tissue mass (LSTM) as well as muscle fiber cross-sectional area (fCSA; vastus lateralis; n = 109; age = 22 ± 2 y, BMI = 24.7 ± 3.1 kg/m2). Over 315 000 genetic polymorphisms were interrogated from muscle using DNA microarrays. First, a targeted investigation was performed where single nucleotide polymorphisms (SNP) identified from a systematic literature review were related to changes in LSTM and fCSA. Next, genome-wide association (GWA) studies were performed to reveal associations between novel SNP targets with …

Nutritional Data And Corresponding Performance Impacts Of Uri Student-Athletes, Abigael Fenbert

Senior Honors Projects

This research project investigates the diets of various sport athletes at the University of Rhode Island. The question that this project aims to answer is if our athletes are meeting recommended daily values nutritionally, and if not, why? Research continues to grow regarding how performance implications are tied to varying nutritional disparities for athletes. Various studies show malnourishment leads to performance decline, increased injury risk, and improper recovery. This is influenced by factors such as deficits in caloric intake, macronutrient and micronutrient availability, and dehydration. For college athletes, a lack of food availability and nutritional knowledge leaves them especially predisposed …

The Effect Of Whey Protein Supplementation At Breakfast On Tryptophan Levels, Food Intake, And Mood In Postmenopausal Women In A 16-Week Randomized Controlled Trial, Danielle Warren

Human Nutrition and Hospitality Management Undergraduate Honors Theses

Whey protein isolate supplementation has been recognized as having potential for regulating appetite, thereby potentially improving mood and food intake.

The objectives of this project were to 1) analyze the effects of high-quality whey protein intake on overall diet, and 2) identify and examine a correlation between tryptophan levels and mood regulation.

This research was conducted using a randomized experimental design. A total of 13 post-menopausal women (12+ months after last reported menstrual cycle) were recruited and allocated to one of two dietary intervention (DI) groups: 1) control (maintain current lifestyle; CON; n = 6), and 2) whey protein isolate …

Determination Of Perceived Calorie Content Of Common Foods, Sarah Leticia Ruiz

Open Access Theses & Dissertations

Currently, dietary weight-loss interventions focus on recommended caloric intake aimed at creating an energy deficit through the use of calorie-based education. This approach assumes individuals can accurately estimate caloric content of foods and beverages, yet little is known about the validity of such assumptions. This study assessed the accuracy of perceptions of calorie content for individual food items and mixed meals and determined its association with education level, nutrition background, body composition, fruit and vegetable intake, and the domains of eating (emotional eating, uncontrolled eating, and cognitive restraint). A cross-sectional survey assessed calorie perceptions using both visual food displays and …

Challenges And Benefits Experienced By Mississippi Schools In The Adoption Of Farm To School Programs, Manuel Aldair Franco Pech

Honors Theses

Mississippi obesity rates are the second highest in the United States. An appropriate target group to combat the state’s high obesity rates are school age children (ages 18 and under), because healthy eating habits developed at this age translate into adult years. An avenue to encourage and develop healthy eating habits are Farm to School (F2S) programs, which provide in-school accessibility to healthy, locally produced foods. The objective of this study was to analyze the results from the 2015 United States Department of Agriculture’s (USDA) F2S Census, which collected details regarding F2S participation across the country, to determine the benefits …

Sarcopenia Screening By Registered Dietitian Nutritionists (Rdns) In The United States (U.S.), Madison Marcom

Electronic Theses and Dissertations

Sarcopenia is a disease of muscle wasting primarily seen in older adults. Although this term was first coined over three decades ago, there is a lack of consensus on a definition, screening criteria, and treatment protocol for sarcopenia. The primary purpose of this study is to determine whether registered dietitian nutritionists (RDNs) in the United States (U.S.) screen for sarcopenia. Study participants were recruited through a randomized email list and included RDNs throughout the U.S. Respondents completed a survey questioning knowledge of sarcopenia, screening tools and company protocols in place, and the need and desire for sarcopenia education. Data revealed …

Unraveling Host-Gut Microbiota Dialogue And Its Impact On Response To Immune Checkpoint Blockade, Alexandria Cogdill

Dissertations and Theses (Open Access)

Cancer is a disease with only one degree of separation, affecting one in two men and one in three women in their lifetimes; accounting for 1 of every 6 deaths. While cancer mortality rates continue to improve, incidence rates are expected to rise and shift through 2050 due to epidemiological and demographic transitions worldwide. As such, it is imperative to continue to investigate and improve our understanding of both disease etiology and hallmarks of response to treatment. Currently, conventional therapies include, but are not limited to, surgery, chemotherapy, and radiotherapy. However, within the past decade, major advances have been made …

Perceived Adult/Child Health And Diet By Snap Usage And Food Security In A Rural, Appalachian Mississippi Community, Georgia Inglis

Honors Theses

This study examined if there were differences in perceived adult health score, perceived adult diet score, parent-perceived child health score, and parent-perceived child diet score by SNAP usage and food security in a rural, Appalachian Mississippi community. Adults (n=1084) with elementary school- aged children were surveyed in a rural, Appalachian Mississippi school district. Demographic, household adult food security (USDA 10-item measure), and perceived health and dietary data were collected. Using IBM SPSS version 24, demographic statistics were calculated to summarize data. Independent samples t-test and one-way ANOVA with Tukey post-hoc test was utilized to assess for differences between groups. P.05) …

Impact Of Different Plant-Based Foods Consumption On The Composition And Diversity Of Gut Microbiota, Ayoub Al Othaim

Graduate Theses and Dissertations

Plant-based diets are primarily derived from plant sources, including fruits and vegetables. Such patterns are associated with health benefits by promoting general health and preventing many diseases and metabolic disorders. Fruits and vegetables are key sources of high-quality nutrients such as dietary fibers and polyphenols. Since they are rich in dietary fibers and polyphenols, whole fruits and vegetables represent unique and somewhat understudied modulators of the gut microbiota and its associated functions. This study aims to (i) investigate the impact of varying dilutions of cherry juices concentrate on the composition of the murine gut microbiota, (ii) investigate the impact of …

Thinking About Availability And Accessibility, Di Fang

Diet, Food, Exercise, and Nutrition (D-FEND)

Food environments are described, including food deserts and food access.

Factors Associated With Underweight Among Two Years Old Children In Dki Jakarta Province (Indonesian Family Life Survey 2014), Nabilla Atelya, Ratu Ayu Dewi Sartika, Winda Mulianingsih

Indonesian Journal of Public Health Nutrition (IJPHN)

A good health status, cognitive development, and productivity cannot be achieved without good nutrition. Nutritional status and its fulfilment of two years old children will be shaping the health status in the next age period. Unfortunately, nutritional problems like underweight is still a significant health problem in Indonesia, especially Special Capital Region of Jakarta. This study used secondary data achieved from Indonesian Family Life Survey 5 data in 2014. This study used a cross-sectional study design with a total of 135 samples of two years old children using a total sampling. Accordingly, the chi square test was used to find …

Underweight In Child Aged 24-59 Months In North Sumatra: The 2014 Indonesia Family Life Survey Data, Salsabila Kurnianingtyas, Ratu Ayu Dewi Sartika, Winda Mulia Ningsih

Indonesian Journal of Public Health Nutrition (IJPHN)

Underweight has the biggest risk against burden of disease. The aim of the study was to determine the factors related with underweight in child aged 24-59 months lived in North Sumatra based on three characteristics caused an underweight; there are child characteristics, maternal characteristics, and parenting characteristics. This study used cross-sectional design and using chi-square statistical analysis. The sample used in this study was 280 child aged 24-59 months living in North Sumatra province, Indonesia. The data was obtained from 2014 Indonesian Family Life Survey collected by RAND Corporation. Prevalence of underweight in child aged 24-59 months lived in North …