Human and Clinical Nutrition Commons^™

Current And Past Menstrual Status Is An Important Determinant Of Femoral Neck Geometry In Exercising Women, Rebecca J. Mallinson, Nancy I. Williams, Jenna C. Gibbs, Karsten Koehler, Heather C.M. Allaway, Emily Southmayd, M. J. De Souza

Department of Nutrition and Health Sciences: Faculty Publications

Menstrual status, both past and current, has been established as an important determinant of bone mineral density (BMD) in young exercising women. However, little is known regarding the association between the cumulative effect of menstrual status and indices of bone health beyond BMD, such as bone geometry and estimated bone strength.

Purpose: This study explores the association between cumulative menstrual status and indices of bone health assessed using dualenergy x-ray absorptiometry (DXA), including femoral neck geometry and strength and areal BMD (aBMD), in exercising women.

Methods: 101 exercising women (22.0 ± 0.4 years, BMI 21.0 ± 0.2 kg/m2, 520±40 min/week …

Hunger Doesn't Take A Spring Break, Jessica Isaacs

Engagement & Service-Learning Summit

The rates of food insecurity amongst Hoosier children is slightly above the national average. For many of these children, school lunches are their primary source of nutrition. During school breaks, these children are at risk of going hungry. While Purdue Nutrition Society wishes that we could help all Hoosier children stay fed with nutritious meals, for now we are focusing on helping 20 local elementary students most at risk of going hungry over spring break. Working with Glen Acres Elementary in Lafayette, Indiana, a school where in 2014, over 71% of the students qualified for free or reduced lunches, we …

Akt-Mtorc1 Signaling Regulates Acly To Integrate Metabolic Input To Control Of Macrophage Activation, Anthony J. Covarrubias, Halil Ibrahim Aksoylar, Jiujiu Yu, Nathaniel W. Snyder, Andrew J. Worth, Shankar S. Iyer, Jiawei Wang, Issam Ben-Sahra, Vanessa Byles, Tiffany Polynne-Stapornkul, Erika C. Espinosa, Dudley Lamming, Brendan D. Manning, Yijing Zhang, Ian A. Blair, Tiffany Horng

Department of Nutrition and Health Sciences: Faculty Publications

Macrophage activation/polarization to distinct functional states is critically supported by metabolic shifts. How polarizing signals coordinate metabolic and functional reprogramming, and the potential implications for control of macrophage activation, remains poorly understood. Here we show that IL-4 signaling co-opts the Akt-mTORC1 pathway to regulate Acly, a key enzyme in Ac-CoA synthesis, leading to increased histone acetylation and M2 gene induction. Only a subset of M2 genes is controlled in this way, including those regulating cellular proliferation and chemokine production. Moreover, metabolic signals impinge on the Akt-mTORC1 axis for such control of M2 activation. We propose that Akt-mTORC1 signaling calibrates metabolic …

Dyslipidemia And Food Security In Low-Income Us Adolescents: National Health And Nutrition Examination Survey, 2003-2010., June M Tester, Barbara A Laraia, Cindy W Leung, Michele L. Mietus-Snyder

Pediatrics Faculty Publications

INTRODUCTION: Low levels of food security are associated with dyslipidemia and chronic disease in adults, particularly in women. There is a gap in knowledge about the relationship between food security among youth and dyslipidemia and chronic disease. We investigated the relationship between food security status and dyslipidemia among low-income adolescents.

METHODS: We analyzed data from adolescents aged 12 to 18 years (N = 1,072) from households with incomes at or below 200% of the federal poverty level from the National Health and Nutrition Examination Survey (NHANES) 2003-2010. We used logistic regression to examine the relationship between household food security status …

A Pilot Study For Plant The Seed: A Nutrition Education Program Using Local Food Environment To Put Theory Into Action, Yeon Bai, Shahla M. Wunderlich, Karen A. Lee

Department of Nutrition and Food Studies Scholarship and Creative Works

The purpose of this study is to implement Plant the Seed, a garden-based nutrition education program designed to reconnect children with locally grown food, food environments of the past and present, and the benefits of eating seasonal foods. The pilot study investigates the environmental context and theory variables known to influence healthy food choice behavior. Social Cognitive Theory (SCT) provided a framework for the program’s curriculum and evaluation. The target audience is middle school students. Plant the Seed is a two-part program. In Part 1 (classroom), students participate in practical, interactive activities based on specific educational objectives that target …

Food Insecurity And Housing Instability In Vulnerable Families, Christian King

Department of Nutrition and Health Sciences: Faculty Publications

Reducing the prevalence of household food insecurity has been a long-standing objective of the federal government. Previous research has found many negative consequences of food insecurity for families and households but has not examined its relationship with housing instability. Using longitudinal data from the Fragile Families and Child Wellbeing Study, difference-in-difference models show that food insecurity is associated with housing instability. The association remains statistically significant after accounting for potential selection and unobserved heterogeneity using propensity score matching and excluding households that experienced prior housing instability from the sample. Examining potential mediating factors, I find that material hardship explains about …

Nutrigenomic Functions Of Ppars In Obesogenic Environments, Soonkyu Chung, Young Jun Kim, Soo Jin Yang, Yunkyoung Lee, Myoungsook Lee

Department of Nutrition and Health Sciences: Faculty Publications

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that mediate the effects of several nutrients or drugs through transcriptional regulation of their target genes in obesogenic environments.This review consists of three parts. First, we summarize current knowledge regarding the role of PPARs in governing the development of white and brown/beige adipocytes from uncommitted progenitor cells. Next, we discuss the interactions of dietary bioactive molecules, such as fatty acids and phytochemicals, with PPARs for the modulation of PPAR-dependent transcriptional activities and metabolic consequences. Lastly, the effects of PPAR polymorphism on obesity and metabolic outcomes are discussed. In this review, we aim …

Glucagon Regulates Hepatic Lipid Metabolism Via Camp And Insig-2 Signaling: Implication For The Pathogenesis Of Hypertriglyceridemia And Hepatic Steatosis, Hai Wang, Miaoyun Zhao, Neetu Sud, Patricia Christian, Jing Shen, Yongyan Song, Anjeza Pashaj, Kezhong Zhang, Timothy P. Carr, Qiaozhu Su

Department of Nutrition and Health Sciences: Faculty Publications

Insulin induced gene-2 (Insig-2) is an ER-resident protein that inhibits the activation of sterol regulatory element-binding proteins (SREBPs). However, cellular factors that regulate Insig-2 expression have not yet been identified. Here we reported that cyclic AMP-responsive element-binding protein H (CREBH) positively regulates mRNA and protein expression of a liver specific isoform of Insig-2, Insig-2a, which in turn hinders SREBP-1c activation and inhibits hepatic de novo lipogenesis. CREBH binds to the evolutionally conserved CRE-BP binding elements located in the enhancer region of Insig-2a and upregulates its mRNA and protein expression. Metabolic hormone glucagon and nutritional fasting activated CREBH, which upregulated expression …

Regulation Of Obesity And Metabolic Complications By Gamma And Delta Tocotrienols, Lu Zhao, Xiefan Fang, Maurice R. Marshall, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Tocotrienols (T3s) are a subclass of unsaturated vitamin E that have been extensively studied for their anti-proliferative, anti-oxidative and anti-inflammatory properties in numerous cancer studies. Recently, T3s have received increasing attention due to their previously unrecognized property to attenuate obesity and its associated metabolic complications. In this review, we comprehensively evaluated the recent published scientific literature about the influence of T3s on obesity, with a particular emphasis on the signaling pathways involved. T3s have been demonstrated in animal models or human subjects to reduce fat mass, body weight, plasma concentrations of free fatty acid, triglycerides and cholesterol, as well as …

Successfully Changing The Landscape Of Information Distribution: Extension Food Website Reaches People Locally And Globally, Alice Henneman, Lisa Franzen-Castle, Kayla Colgrove, Vishal Singh

Department of Nutrition and Health Sciences: Faculty Publications

The goal of the Food website was to develop Internet-based content that was relevant and reached the general public and multiplier groups, such as educators, health professionals, and media outlets. The purpose of this paper was to examine whether a multi-modal approach to information delivery through increases in and changes to content, electronic mailing list creation, and social media posting impacted user access, traffic channels, and referrals from 2010 to 2014. When comparing 2010-2011 versus 2013-2014, there was a 150% increase in total pageviews, 197% increase in unique pageviews, and a 39% increase in average time spent on a page. …

Public Health Leaders' Perceptions Of And Attitudes Concerning Eating Disorders, Karin L. Lightfoot

Walden Dissertations and Doctoral Studies

Eating disorders are associated with high mortality rates. Most eating disorder prevention research is conducted within the fields of psychology and psychiatry, not in public health. This gap in public health research can lead to insufficient attention to the root causes of eating disorders and minimal upstream prevention efforts. The purpose of this phenomenological study was to identify public health leaders' perceptions of and attitudes concerning eating disorders as a public health issue. Objectification theory was used to describe how societal expectations have created an environment in which people's self-worth is based on their outward physical appearance. Ecological theory was …

Implementing Pasteurized Donor Human Milk Programs In Level One And Two Nurseries: Policies, Barriers, And Successes, Rebecca Phipps Smeltzer

Honors Theses and Capstones

Pasteurized donor human milk (PDHM) as feeding supplementation has been shown to prevent and lower rates of gastrointestinal infection and increase exclusive human milk consumption (EHM) in critically-ill, low birthweight and premature infants. Policies/ procedures for the use of PDHM in “well” newborns and low birth weight newborns with non-life-threatening illness, level I and II nurseries, respectively, have not been established. The objective of this research is to gather and summarize policies/procedures and experiences from four hospitals in the northeast US that use PDHM in level I/II nurseries. Data was collected from interviews with hospital administrators and each hospital’s PDHM …

A Dietary Approach To Cardiovascular Disease And Cancer: Does A Plant Based Diet Help Prevent And Reverse Cardiovascular Disease And Cancer?, Chana Wircberg

The Science Journal of the Lander College of Arts and Sciences

Modern Western societies seem to suffer from a veritable epidemic of serious diseases, two of the most serious of which are cardiovascular disease and cancer. In contrast, hunter and gatherer groups have a very low incidence of such diseases. Despite the diversity of hunter and gather diets, they all share the same characteristic: the absence of a Western diet. This suggests that there is something uniquely inflammatory about a Western diet, which is high in both fats and carbohydrates. Departures from a Western diet appear to result in better health. Experimental studies have shown that heart disease can be reversed …

Evaluation Of Protein Source At Breakfast On Energy Metabolism, Metabolic Health, And Food Intake: A Pilot Study, Lauren A. Cambias, Brianna L. Neumann, Charlayne Mitchell, Jamie I. Baum

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Over 30% of adults in the U.S. are obese. A primary contributor to obesity is an unhealthy diet related to imbalanced macronutrients. Diets higher in protein (PRO) rather than carbohydrate (CHO) are associated with increased energy expenditure (EE) and reduced food intake. The objective of this pilot study was to determine if protein source at breakfast influences EE in young men (n = 4; ages 18-35). Participants consumed three isocaloric (whey (WP), pea (PP), beef (BP); 275 kcal, 62% PRO, 23% CHO, 15% Fat) drinks in a randomized, crossover design study with a one-week washout period (time between the administration …

Ignite-Sparking Youth To Create Healthy Communities: A Protocol For A Community-Centered Effort For The Prevention Of Adolescent Obesity, Tandalayo Kidd, Erika Lindshield, Kendra Kattelmann, Koushik Adhikari, Nancy Muturi, Susan Zies

Health and Nutritional Sciences Faculty Publications

Objective: To observe outcomes of a community-centered approach to identifying behavioral and environmental factors that influence overweight and obesity in 6th-8th grade youth in selected low income, racial/ethnic communities.
Design: Five-year, tri-state, quasi-experimental design with environmental assessments and a questionnaire measuring nutrition and physical activity knowledge and behavior conducted in all communities at pre and post.
Setting: Low-income, minority communities targeting 6th-8th grade youth. Participants: One experimental and one control communities will be selected via each state’s Cooperative Extension network through an application and review process with the random selection of participating communities.
Intervention(s): Academic institutions will work with community …

Assessing Physical Activity Determinants In Urban Settings: Comparison Of Perceptions And Environmental Audit Findings, Daniel Remley, Susan Zies, Beth Stefura, Ryan Leone, Kendra Kattelmann, Tandalayo Kidd

Health and Nutritional Sciences Faculty Publications

Sedentary lifestyles are a contributor to obesity and urban adolescents are less physically active than rural adolescents. Supportive physical activity environments, understood as the geography, observations, and perceptions of features such as recreational facilities, sidewalks, bike lanes, traffic patterns, etc., have been positively associated with adolescent physical activity behaviors within urban settings. As part of a Socio-Ecological intervention to improve physical activity behavior, the Physical Activity Resource Assessment (PARA), the Active Neighborhood Checklist (ANC), and focus groups were used to assess the physical activity influences within an urban middle school and surrounding community. The assessments suggested that lack of parks, …

Lifestyle Contributors To Cardiovascular Disease Risk, Adam J. Berrones

Theses and Dissertations--Kinesiology and Health Promotion

Aortic stiffness is an independent risk factor that has prognostic value regarding future cardiovascular disease (CVD) events such as myocardial infarction, strokes, and heart failure. Although death rates due to coronary heart disease have declined in recent years, the leading global killer remains CVD and prevalence is still high. Understanding lifestyle contributors associated with aortic stiffness would provide the public with insight into targeting key health-related behaviors.

The purpose of this observational study was to examine the association of physical activity, physical function, and dietary quality as independent factors contributing to aortic stiffness in apparently healthy middle aged men. Fifty-two …

Promoting Healthy Home-Cooked Family Meals: Evaluation Of A Social Marketing Program Targeting Low-Income Mothers, Mollie Y. Dawahare

Theses and Dissertations--Nutrition and Food Systems

Objective: Evaluate how a social marketing approach compares to traditional nutrition education curriculum for promoting behavioral changes related to eating and food.

Design: Nonequivalent comparison group, entry-exit design. Participants from 12 Kentucky counties assigned either comparison or pilot group. Comparison group received traditional nutrition education curriculum and pilot group received the social marketing program, Cook Together, Eat Together (CTET) curriculum. EFNEP’s Behavior Checklist and 24-Hour Dietary Recall were administered at entry and exit of the 8-week programs.

Participants: Females (18-72 years of age) from families eligible to receive SNAP benefits (n=64 comparison group participants, n=60 pilot group participants).

Intervention: …

Color Your Plate Nutrition Intervention: Using Exposure Interventions To Increase Fruit And Vegetable Intake In Older Adults Attending Congregate Meal Sites, Alyson D. Humphrey

Theses and Dissertations--Nutrition and Food Systems

The aims of the Color Your Plate nutrition intervention were to increase intake of fruits and vegetables and increase motivators and decrease barriers to consuming fruits and vegetables rich in older-adults who regularly attend congregate meal sites. In this quasiexperimental pilot study, a convenience sample (n=35) of older adults at two intervention and two control sites completed pre- and post-surveys. Following the five-lesson curriculum, intervention participants reported greater intakes of fruits and vegetables (mean change increase of 3.47 ± 2.38 servings/week) and significant increases in days having consumed 4.5 cups or more of fruits and vegetables (p=.0004), incorporation of fruits …

The Apoa5 Rs662799 Polymorphism Is Associated With Dyslipidemia And The Severity Of Coronary Heart Disease In Chinese Women, Yanmei Wang, Zhan Lu, Jingxiao Zhang, Yang Yang, Jing Shen, Xiaoming Zhang, Yongyan Song

Department of Nutrition and Health Sciences: Faculty Publications

Background: The APOA5 rs662799 polymorphism has been widely reported regarding its associations with the plasma lipid levels and the occurrence of coronary heart disease (CHD), whereas its relationship with the severity of CHD has not yet been explored.

Methods: Four hundred and seventy-eight angiografically defined subjects (325 CHD patients and 153 CHD-free controls) were enrolled in this study. The rs662799 polymorphism was genotyped, and the fasting lipid data were collected for all participants. The severity of CHD was evaluated for the CHD patients by using Gensini scores.

Results: The variant C allele of the rs662799 polymorphism was associated with lower …

Carbohydrate Intake In Form Of Gel Is Associated With Increased Gastrointestinal Distress But Not With Performance Differences Compared With Liquid Carbohydrate Ingestion During Simulated Long-Distance Triathlon, Mahdi Sareban, David Zügel, Karsten Koehler, Paul Hartveg, Martina Zügel, Uwe Schumann, Jürgen Michael Steinacker, Gunnar Treff

Department of Nutrition and Health Sciences: Faculty Publications

The ingestion of exogenous carbohydrates (CHO) during prolonged endurance exercise, such as long-distance triathlon, is considered beneficial with regard to performance. However, little is known about whether this performance benefit differs among different forms of CHO administration. To this end, the purpose of our study was to determine the impact of CHO ingestion from a semisolid source (GEL) on measures of performance and gastrointestinal (GI) comfort compared with CHO ingestion from a liquid source (LIQ). Nine well-trained triathletes participated in this randomized crossover study. Each participant completed a 60-min swim, 180-min bike exercise, and a 60-min all-out run in a …

Low Resting Metabolic Rate In Exercise-Associated Amenorrhea Is Not Due To A Reduced Proportion Of Highly Active Metabolic Tissue Compartments, Karsten Koehler, Nancy I. Williams, Rebecca J. Mallinson, Emily A. Southmayd, Heather C.M. Allaway, Mary Jane De Souza

Department of Nutrition and Health Sciences: Faculty Publications

Exercising women with menstrual disturbances frequently display a low resting metabolic rate (RMR) when RMR is expressed relative to body size or lean mass. However, normalizing RMR for body size or lean mass does not account for potential differences in the size of tissue compartments with varying metabolic activities. To explore whether the apparent RMR suppression in women with exercise-associated amenorrhea is a consequence of a lower proportion of highly active metabolic tissue compartments or the result of metabolic adaptations related to energy conservation at the tissue level, RMR and metabolic tissue compartments were compared among exercising women with amenorrhea …

Effects Of Short-Term Dynamic Constant External Resistance Training And Subsequent Detraining On Strength Of The Trained And Untrained Limbs: A Randomized Trial, Pablo B. Costa, Trent J. Herda, Ashley A. Herda, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

Short-term resistance training has been shown to increase isokinetic muscle strength and performance after only two to nine days of training. The purpose of this study was to examine the effects of three days of unilateral dynamic constant external resistance (DCER) training and detraining on the strength of the trained and untrained legs. Nineteen men were randomly assigned to a DCER training group or a non-training control group. Subjects visited the laboratory eight times, the first visit was a familiarization session, the second visit was a pre-training assessment, the subsequent three visits were for training sessions (if assigned to the …

Mental Health Disparities Within The Lgbt Population: A Comparison Between Transgender And Nontransgender Individuals, Dejun Su, Jay A. Irwin, Christopher Fisher, Athena Ramos, Megan Kelley, Diana Ariss Rogel Mendoza, Jason D. Coleman

Department of Nutrition and Health Sciences: Faculty Publications

Purpose: This study assessed within a Midwestern LGBT population whether, and the extent to which, transgender identity was associated with elevated odds of reported discrimination, depression symptoms, and suicide attempts.

Methods: Based on survey data collected online from respondents who self-identified as lesbian, gay, bisexual, and/or transgender persons over the age of 19 in Nebraska in 2010, this study performed bivariate t- or chisquare tests and multivariate logistic regression analysis to examine differences in reported discrimination, depression symptoms, suicide attempts, and self-acceptance of LGBT identity between 91 transgender and 676 nontransgender respondents.

Results: After controlling for the effects …

Nutrition Knowledge Among A Predominantly Hispanic College Population, Heather Sandford

Open Access Theses & Dissertations

ABSTRACT

Many chronic diseases such as Type 2 diabetes, cardiovascular disease and some types of cancer are prevalent and have been associated with unhealthy eating patterns. At the same time overweight and obesity are contributing factors to the development of these conditions. There are multiple factors contributing to overweight and obesity. Some of these include a frequent consumption of unhealthy or high energy-dense foods combined with the lack of physical activity. A true understanding and foundation of proper nutrition allows people to make healthy eating choices. It has been documented that among the population, college students have a limited nutrition …

The Relationship Between Nutrient Intake And Social Emotional Functioning In Preschool Children, Tracy L. Daniel

Walden Dissertations and Doctoral Studies

Mental health disorders are rising in children and being referred to as an epidemic. Numerous studies have shown micronutrient deficiencies and poor diet quality are suspected of playing a contributory role in the escalation of certain disorders. However, there is no research in young children focusing specifically on social emotional disorders and possible links to nutrition. Conventional treatment for social emotional disorders in children typically involves medication. Parents are increasingly turning to complementary and alternative medicine to treat their children with a method that is individualized and holistic. The biopsychosocial model provided the theoretical framework for this correlational study that …

Methylmercury Exposure Via Canned Tuna Fish Consumption And Breast Cancer, Jennifer Bodenrader

Walden Dissertations and Doctoral Studies

Widespread consumption of canned tuna fish since the 1950s may explain some of the increase in breast cancer prevalence in the United States and Europe. Although canned tuna is the primary source of human exposure to methylmercury, its role as an estrogen activating metalloestrogen has been overlooked in the etiology and incidence of breast cancer. Carcinogenic theory asserts that increased exposure to estrogen elevates the risk of breast cancer. The purpose of this population-based, case control study was to examine the association between canned tuna consumption, total blood mercury, and breast cancer in the NHANES 2003-2006 surveys. A multivariable logistic …

Disparities In Access To Preventive Health Care Services Among Insured Children In A Cross Sectional Study, Christian King

Department of Nutrition and Health Sciences: Faculty Publications

Children with insurance have better access to care and health outcomes if their parents also have insurance. However, little is known about whether the type of parental insurance matters. This study attempts to determine whether the type of parental insurance affects the access to health care services of children. I used data from the 2009–2013 Medical Expenditure Panel Survey and estimated multivariate logistic regressions (N=26,152). I estimated how family insurance coverage affects the probability that children have a usual source of care, well-child visits in the past year, unmet medical and prescription needs, less than 1 dental visit per year, …

Four Weeks Of High- Versus Low-Load Resistance Training To Failure On The Rate Of Torque Development, Electromechanical Delay, And Contractile Twitch Properties, N.D.M. Jenkins, Terry J. Housh, S.L. Buckner, H.C. Bergstrom, C. M. Smith, Kristen C. Cochrane, E.C. Hill, Amelia A. Miramonti, Richard J. Schmidt, G. O. Johnson, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

The purpose of this study was to investigate the effects of 4-weeks of high- versus low-load resistance training to failure on rate of torque development (RTD), electromechanical delay (EMD), and contractile twitch characteristics. Fifteen men (mean±SD; age=21.7±2.4 yrs) were randomly assigned to either a high- (80% 1RM; n=7) or low-load (30% 1RM; n=8) training group and completed elbow flexion resistance training to failure 3 times per week for 4 weeks. The participants were tested at baseline, 2-, and 4-weeks of training. Peak RTD (pRTDV) and RTD at 0-30 (RTD30V), 0-50 (RTD50V), 0-100 (RTD100V), and 0-200 (RTD200V) ms, integrated EMG amplitude …

Soft Drinks Consumption And Child Behaviour Problems: The Role Of Food Insecurity And Sleep Patterns, Christian King

Department of Nutrition and Health Sciences: Faculty Publications

Objective: To examine whether the association between soft drinks consumption and child behaviour problems differs by food security status and sleep patterns in young children.

Design: Cross-sectional observational data from the Fragile Families and Child Wellbeing Study (FFCWS), which collected information on food insecurity, soft drinks consumption, sleep patterns and child behaviour problems. Bivariate and multivariate ordinary least-squares regression analyses predicting child behaviour problems and accounting for socio-economic factors and household characteristics were performed.

Setting: Twenty urban cities in the USA with a population of 200 000 or more.

Subjects: Parental interviews of 2829 children who were about 5 years …