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Articles 1 - 4 of 4
Full-Text Articles in Systems Neuroscience
Low-Dimensional Criticality Embedded In High-Dimensional Awake Brain Dynamics, Antonio J. Fontenele, J. Samuel Sooter, V. Kindler Norman, Shree Hari Gautam, Woodrow L. Shew
Low-Dimensional Criticality Embedded In High-Dimensional Awake Brain Dynamics, Antonio J. Fontenele, J. Samuel Sooter, V. Kindler Norman, Shree Hari Gautam, Woodrow L. Shew
Physics Faculty Publications and Presentations
Whether cortical neurons operate in a strongly or weakly correlated dynamical regime determines fundamental information processing capabilities and has fueled decades of debate. We offer a resolution of this debate; we show that two important dynamical regimes, typically considered incompatible, can coexist in the same local cortical circuit by separating them into two different subspaces. In awake mouse motor cortex, we find a low-dimensional subspace with large fluctuations consistent with criticality—a dynamical regime with moderate correlations and multi-scale information capacity and transmission. Orthogonal to this critical subspace, we find a high-dimensional subspace containing a desynchronized dynamical regime, which may optimize …
Sensory Input To Cortex Encoded On Low-Dimensional Periphery-Correlated Subspaces, Andrea K. Barreiro, Antonio J. Fontenele, Cheng Ly, Prashant Chama Raju, Shree Hari Gautam, Woodrow L. Shew
Sensory Input To Cortex Encoded On Low-Dimensional Periphery-Correlated Subspaces, Andrea K. Barreiro, Antonio J. Fontenele, Cheng Ly, Prashant Chama Raju, Shree Hari Gautam, Woodrow L. Shew
Physics Faculty Publications and Presentations
As information about the world is conveyed from the sensory periphery to central neural circuits, it mixes with complex ongoing cortical activity. How do neural populations keep track of sensory signals, separating them from noisy ongoing activity? Here, we show that sensory signals are encoded more reliably in certain low-dimensional subspaces. These coding subspaces are defined by correlations between neural activity in the primary sensory cortex and upstream sensory brain regions; the most correlated dimensions were best for decoding. We analytically show that these correlation-based coding subspaces improve, reaching optimal limits (without an ideal observer), as noise correlations between cortex …
Feedforward And Feedback Signals In The Olfactory System, Srimoy Chakraborty
Feedforward And Feedback Signals In The Olfactory System, Srimoy Chakraborty
Graduate Theses and Dissertations
The conglomeration of myriad activities in neural systems often results in prominent oscillations. The primary goal of the research presented in this thesis was to study effects of sensory stimulus on the olfactory system of rats, focusing on the olfactory bulb (OB) and the anterior piriform cortex (aPC). Extracellular electrophysiological measurements revealed distinct frequency bands of oscillations in OB and aPC. However, how these oscillatory fluctuations help the animal to process sensory input is not clearly understood. Here we show high frequency oscillations in olfactory bulb carry feedforward signals to anterior piriform cortex whereas feedback from the aPC is predominantly …
Effects Of Head Position And Head-Supported Mass On Nerve Function Of The Flexor Carpi Radialis Muscle In Healthy Individuals, Bethany Lauren Shivers
Effects Of Head Position And Head-Supported Mass On Nerve Function Of The Flexor Carpi Radialis Muscle In Healthy Individuals, Bethany Lauren Shivers
Graduate Theses and Dissertations
Long-term exposure to head-supported mass (HSM) has been linked with spinal degeneration including foraminal stenosis and disc deterioration. Anecdotally, HSM has also been linked to neck and arm pain and muscle atrophy, but nerve function has not been tested specifically. The combined effect of various head positions and HSM may be sufficient to compress the nerve root in aviators and Soldiers during job performance, potentially leading to short- and long-term neuromuscular effects. The Hoffmann (H) reflex, a well-established measure of nerve function, has shown to be sensitive to changes in nerve root space which occurs with different head positions. This …