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Molecular and Cellular Neuroscience Commons™
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Articles 1 - 30 of 63
Full-Text Articles in Molecular and Cellular Neuroscience
Glycemic Challenge Is Associated With The Rapid Cellular Activation Of The Locus Ceruleus And Nucleus Of Solitary Tract: Circumscribed Spatial Analysis Of Phosphorylated Map Kinase Immunoreactivity, Arshad Khan
Selected Works Temporary Series
Rodent studies indicate that impaired glucose utilization or hypoglycemia is associated with the cellular activation of neurons in the medulla (Winslow, 1733) (MY), believed to control feeding behavior and glucose counterregulation. However, such activation has been tracked primarily within hours of the challenge, rather than sooner, and has been poorly mapped within standardized brain atlases. Here, we report that, within 15 min of receiving 2-deoxy-D-glucose (2-DG; 250 mg/kg, i.v.), which can trigger glucoprivic feeding behavior, marked elevations were observed in the numbers of rhombic brain (His, 1893) (RB) neuronal cell profiles immunoreactive for the cellular activation marker(s), phosphorylated p44/42 MAP …
A Historical Perspective On Training Students To Create Standardized Maps Of Novel Brain Structure: Newly-Uncovered Resonances Between Past And Present Research-Based Neuroanatomy Curricula, Arshad Khan, Christina D'Arcy, Jeffrey Olimpo
A Historical Perspective On Training Students To Create Standardized Maps Of Novel Brain Structure: Newly-Uncovered Resonances Between Past And Present Research-Based Neuroanatomy Curricula, Arshad Khan, Christina D'Arcy, Jeffrey Olimpo
Selected Works Temporary Series
Recent efforts to reform postsecondary STEM education in the U.S. have resulted in the creation of course-based undergraduate research experiences (CUREs), which, among other outcomes, have successfully retained freshmen in their chosen STEM majors and provided them with a greater sense of identity as scientists by enabling them to experience how research is conducted in a laboratory setting. In 2014, we launched our own laboratory-based CURE, Brain Mapping & Connectomics (BMC). Now in its seventh year, BMC trains University of Texas at El Paso (UTEP) undergraduates to identify and label neuron populations in the rat brain, analyze their cytoarchitecture, and …
Distributions Of Hypothalamic Neuron Populations Co-Expressing Tyrosine Hydroxylase And The Vesicular Gaba Transporter In The Mouse., Kenichiro Negishi, Mikayla Payant, Kayla Schumacker, Gabor Wittman, Rebecca Butler, Ronald Lechan, Harry Steinbusch, Arshad Khan, Melissa Chee
Distributions Of Hypothalamic Neuron Populations Co-Expressing Tyrosine Hydroxylase And The Vesicular Gaba Transporter In The Mouse., Kenichiro Negishi, Mikayla Payant, Kayla Schumacker, Gabor Wittman, Rebecca Butler, Ronald Lechan, Harry Steinbusch, Arshad Khan, Melissa Chee
Selected Works Temporary Series
No abstract provided.
Cognitive And Non-Cognitive Outcomes Associated With Student Engagement In A Novel Brain Chemoarchitecture Mapping Course-Based Undergraduate Research Experience., Christina D'Arcy, Anais Martinez, Arshad Khan, Jeffrey Olimpo
Cognitive And Non-Cognitive Outcomes Associated With Student Engagement In A Novel Brain Chemoarchitecture Mapping Course-Based Undergraduate Research Experience., Christina D'Arcy, Anais Martinez, Arshad Khan, Jeffrey Olimpo
Selected Works Temporary Series
No abstract provided.
Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Arshad Khan, Alice Grant, Anais Martinez, Gully Burns, Brendan Thatcher, Vishwanath Anekonda, Benjamin Thompson, Zachary Roberts, Daniel Moralejo, James Blevins
Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Arshad Khan, Alice Grant, Anais Martinez, Gully Burns, Brendan Thatcher, Vishwanath Anekonda, Benjamin Thompson, Zachary Roberts, Daniel Moralejo, James Blevins
Selected Works Temporary Series
This article, which includes novel unpublished data along with commentary and analysis,focuses on approaches to link transcriptomic, proteomic, and peptidomic datasets mined frombrain tissue to the original locations within the brain that they are derived from using digital atlasmapping techniques. We use, as an example, the transcriptomic, proteomic and peptidomicanalyses conducted in the mammalian hypothalamus. Following a brief historical overview, wehighlight studies that have mined biochemical and molecular information from the hypothalamusand then lay out a strategy for how these data can be linked spatially to the mapped locations in acanonical brain atlas where the data come from, thereby allowing …
Microarray Analysis Of Aging-Associated Immune System Alterations In The Rostral Ventrolateral Medulla Of F344 Rats, Sivasai Balivada, Chanran Ganta, Yongqing Zhang, Hitesh Pawar, Richard Ortiz, Kevin Becker, Arshad Khan, Michael Kenney
Microarray Analysis Of Aging-Associated Immune System Alterations In The Rostral Ventrolateral Medulla Of F344 Rats, Sivasai Balivada, Chanran Ganta, Yongqing Zhang, Hitesh Pawar, Richard Ortiz, Kevin Becker, Arshad Khan, Michael Kenney
Selected Works Temporary Series
The rostral ventrolateral medulla (RVLM) is an area of the brain stem that contains diverse neural substrates that are involved in systems critical for physiological function. There is evidence that aging affects some neural substrates within the RVLM, although age-related changes in RVLM molecular mechanisms are not well established. The goal of the present study was to characterize the transcriptomic profile of the aging RVLM and to test the hypothesis that aging is associated with altered gene expression in the RVLM, with an emphasis on immune system associated gene transcripts. RVLM tissue punches from young, middle-aged, and aged F344 rats …
Enhanced Nicotine Self-Administration And Suppressed Dopaminergic Systems In A Rat Model Of Diabetes, Laura O'Dell
Enhanced Nicotine Self-Administration And Suppressed Dopaminergic Systems In A Rat Model Of Diabetes, Laura O'Dell
Selected Works Temporary Series
Patients with diabetes display a heightened propensity to use tobacco; however, it is unclear whether they experience enhanced rewarding effects of nicotine. Thus, this study examined the reinforcing effects of nicotine in a rodent model of diabetes involving administration of streptozotocin (STZ), a drug that is toxic to pancreatic insulin-producing cells. The first study compared STZ- and vehicle-treated rats that had 23-hour access to intravenous self-administration (IVSA) of nicotine or saline and concomitant access to food and water. In order to examine the contribution of dopamine to our behavioral effects, dopamine transporter (DAT), D1 and D2 receptor levels were compared …
Effect Of Nicotine On Body Composition, Laura O'Dell
Effect Of Nicotine On Body Composition, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Map Kinases Couple Hindbrain-Derived Catecholamine Signals To Hypothalamic Adrenocortical Control Mechanisms During Glycemia-Related Challenges, Arshad Khan, Kimberly Kaminski, Graciela Sanchez-Watts, Todd Ponzio, J. Kuzmiski, Jaideep Bains, Alan Watts
Map Kinases Couple Hindbrain-Derived Catecholamine Signals To Hypothalamic Adrenocortical Control Mechanisms During Glycemia-Related Challenges, Arshad Khan, Kimberly Kaminski, Graciela Sanchez-Watts, Todd Ponzio, J. Kuzmiski, Jaideep Bains, Alan Watts
Selected Works Temporary Series
No abstract provided.
Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell
Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell
Selected Works Temporary Series
No abstract provided.
A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell
A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Pdf Of All O'Dell Manuscripts, Laura O'Dell
Pdf Of All O'Dell Manuscripts, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell
Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell
The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell
Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell
Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell
Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
A Role For The Forebrain In Mediating Time-Of-Day Differences In Glucocorticoid Counterregulatory Responses To Hypoglycemia In Rats, Lori Gorton, Arshad Khan, Maryann Bohland, Graciela Sanchez-Watts, Casey Donovan, Alan Watts
A Role For The Forebrain In Mediating Time-Of-Day Differences In Glucocorticoid Counterregulatory Responses To Hypoglycemia In Rats, Lori Gorton, Arshad Khan, Maryann Bohland, Graciela Sanchez-Watts, Casey Donovan, Alan Watts
Selected Works Temporary Series
No abstract provided.
Catecholaminergic Control Of Mitogen-Activated Protein Kinase Signaling In Paraventricular Neuroendocrine Neurons In Vivo And In Vitro: A Proposed Role During Glycemic Challenges, Arshad Khan, Todd Ponzio, Graciela Sanchez-Watts, B. Stanley, Glenn Hatton, Alan Watts
Catecholaminergic Control Of Mitogen-Activated Protein Kinase Signaling In Paraventricular Neuroendocrine Neurons In Vivo And In Vitro: A Proposed Role During Glycemic Challenges, Arshad Khan, Todd Ponzio, Graciela Sanchez-Watts, B. Stanley, Glenn Hatton, Alan Watts
Selected Works Temporary Series
No abstract provided.
Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell
Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell
Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell
Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
“Nicotine Deprivation Effect” In Rats With Intermittent 23-Hour Access To Intravenous Nicotine Self-Administration, Laura O'Dell
“Nicotine Deprivation Effect” In Rats With Intermittent 23-Hour Access To Intravenous Nicotine Self-Administration, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Viral Vector-Induced Amygdala Npy Overexpression Reverses Increased Alcohol Intake Caused By Repeated Deprivations In Wistar Rats, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Activation In Neural Networks Controlling Ingestive Behaviors: What Does It Mean, And How Do We Map And Measure It?, Alan Watts, Arshad Khan, Graciela Sanchez-Watts, Dawna Salter, Christina Neuner
Activation In Neural Networks Controlling Ingestive Behaviors: What Does It Mean, And How Do We Map And Measure It?, Alan Watts, Arshad Khan, Graciela Sanchez-Watts, Dawna Salter, Christina Neuner
Selected Works Temporary Series
No abstract provided.