Open Access. Powered by Scholars. Published by Universities.®
Molecular and Cellular Neuroscience Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Texas at El Paso (20)
- University of Kentucky (16)
- Rowan University (10)
- Embry-Riddle Aeronautical University (7)
- Roseman University of Health Sciences (7)
-
- Liberty University (6)
- University of Louisville (6)
- University of Central Florida (5)
- City University of New York (CUNY) (4)
- The Texas Medical Center Library (4)
- University of New Mexico (4)
- University of Connecticut (3)
- Virginia Commonwealth University (3)
- Claremont Colleges (2)
- James Madison University (2)
- Nova Southeastern University (2)
- University of Arkansas, Fayetteville (2)
- University of Nebraska - Lincoln (2)
- University of Tennessee, Knoxville (2)
- University of the Incarnate Word (2)
- West Virginia University (2)
- American University in Cairo (1)
- Arcadia University (1)
- California Polytechnic State University, San Luis Obispo (1)
- Dartmouth College (1)
- DePaul University (1)
- East Tennessee State University (1)
- Grand Valley State University (1)
- Illinois Math and Science Academy (1)
- LSU Health New Orleans (1)
- Keyword
-
- Hypothalamus (8)
- Stress (7)
- Neuroinflammation (6)
- Neuroscience (6)
- Alzheimer's Disease (5)
-
- Neurodegeneration (5)
- Neurons (5)
- 2-deoxyglucose (4)
- Catecholamine (4)
- Tau (4)
- Alzheimer’s disease (3)
- Biomarkers (3)
- Glutamate (3)
- Hippocampus (3)
- Humans (3)
- Inflammation (3)
- Male (3)
- MiRNA (3)
- Neurodegenerative Diseases (3)
- Neurogenesis (3)
- Rats (3)
- Spaceflight (3)
- Spinal cord injury (3)
- APOE (2)
- Aging (2)
- Alzheimer's (2)
- Animals (2)
- Anxiety (2)
- Astrocytes (2)
- Astrogliosis (2)
- Publication Year
- Publication
-
- Departmental Papers (Biology) (10)
- Selected Works Temporary Series (10)
- Annual Research Symposium (7)
- Graduate School of Biomedical Sciences Theses and Dissertations (7)
- Publications (7)
-
- Honors Undergraduate Theses (5)
- Dissertations and Theses (Open Access) (4)
- Senior Honors Theses (4)
- Biomedical Sciences ETDs (3)
- The Cardinal Edge (3)
- Theses & Dissertations (3)
- Theses and Dissertations--Neuroscience (3)
- Theses and Dissertations--Physiology (3)
- CMC Senior Theses (2)
- Graduate Theses and Dissertations (2)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (2)
- Honors Scholar Theses (2)
- Pharmacology and Nutritional Sciences Faculty Publications (2)
- Publications and Research (2)
- Pursuit - The Journal of Undergraduate Research at The University of Tennessee (2)
- Rowan-Virtua Research Day (2)
- Sanders-Brown Center on Aging Faculty Publications (2)
- Senior Honors Projects, 2010-2019 (2)
- Theses and Dissertations (2)
- Animal Sentience (1)
- Appalachian Student Research Forum (1)
- Biomedical and Pharmaceutical Sciences Faculty Publications (1)
- CAHSS Intellectual Conversations (1)
- Capstone Showcase (1)
- College of Arts & Sciences Senior Theses (1)
- Publication Type
- File Type
Articles 121 - 136 of 136
Full-Text Articles in Molecular and Cellular Neuroscience
Catecholaminergic Control Of Mitogen-Activated Protein Kinase Signaling In Paraventricular Neuroendocrine Neurons In Vivo And In Vitro: A Proposed Role During Glycemic Challenges, Khan, Todd Ponzio, Graciela Sanchez-Watts, B. Stanley, Glenn Hatton, Alan Watts
Catecholaminergic Control Of Mitogen-Activated Protein Kinase Signaling In Paraventricular Neuroendocrine Neurons In Vivo And In Vitro: A Proposed Role During Glycemic Challenges, Khan, Todd Ponzio, Graciela Sanchez-Watts, B. Stanley, Glenn Hatton, Alan Watts
Departmental Papers (Biology)
No abstract provided.
Activation In Neural Networks Controlling Ingestive Behaviors: What Does It Mean, And How Do We Map And Measure It?, Alan Watts, Arshad Khan, Graciela Sanchez-Watts, Dawna Salter, Christina Neuner
Activation In Neural Networks Controlling Ingestive Behaviors: What Does It Mean, And How Do We Map And Measure It?, Alan Watts, Arshad Khan, Graciela Sanchez-Watts, Dawna Salter, Christina Neuner
Selected Works Temporary Series
No abstract provided.
Activation In Neural Networks Controlling Ingestive Behaviors: What Does It Mean, And How Do We Map And Measure It?, Watts, Arshad Khan, Graciela Sanchez-Watts, Dawna Salter, Christina Neuner
Activation In Neural Networks Controlling Ingestive Behaviors: What Does It Mean, And How Do We Map And Measure It?, Watts, Arshad Khan, Graciela Sanchez-Watts, Dawna Salter, Christina Neuner
Departmental Papers (Biology)
No abstract provided.
Lateral Hypothalamic Signaling Mechanisms Underlying Feeding Stimulation: Differential Contributions Of Src Family Tyrosine Kinases To Feeding Triggered Either By Nmda Injection Or By Food Deprivation, Arshad Khan, Herman Cheung, Elizabeth Gillard, Jennifer Palarca, Derek Welsbie, James Gurd, B. Stanley
Lateral Hypothalamic Signaling Mechanisms Underlying Feeding Stimulation: Differential Contributions Of Src Family Tyrosine Kinases To Feeding Triggered Either By Nmda Injection Or By Food Deprivation, Arshad Khan, Herman Cheung, Elizabeth Gillard, Jennifer Palarca, Derek Welsbie, James Gurd, B. Stanley
Selected Works Temporary Series
No abstract provided.
Lateral Hypothalamic Signaling Mechanisms Underlying Feeding Stimulation: Differential Contributions Of Src Family Tyrosine Kinases To Feeding Triggered Either By Nmda Injection Or By Food Deprivation, Khan, Herman Cheung, Elizabeth Gillard, Jennifer Palarca, Derek Welsbie, James Gurd, B. Stanley
Lateral Hypothalamic Signaling Mechanisms Underlying Feeding Stimulation: Differential Contributions Of Src Family Tyrosine Kinases To Feeding Triggered Either By Nmda Injection Or By Food Deprivation, Khan, Herman Cheung, Elizabeth Gillard, Jennifer Palarca, Derek Welsbie, James Gurd, B. Stanley
Departmental Papers (Biology)
No abstract provided.
Intravenous 2-Deoxy-D-Glucose Injection Rapidly Elevates Levels Of The Phosphorylated Forms Of P44/42 Mitogen-Activated Protein Kinases (Extracellularly Regulated Kinases 1/2) In Rat Hypothalamic Parvicellular Paraventricular Neurons, Arshad Khan, Alan Watts
Selected Works Temporary Series
No abstract provided.
Intravenous 2-Deoxy-D-Glucose Injection Rapidly Elevates Levels Of The Phosphorylated Forms Of P44/42 Mitogen-Activated Protein Kinases (Extracellularly Regulated Kinases 1/2) In Rat Hypothalamic Parvicellular Paraventricular Neurons, Khan, Alan Watts
Departmental Papers (Biology)
No abstract provided.
Prolonged Cyclooxygenase-2 Induction In Neurons And Glia Following Traumatic Brain Injury In The Rat, Kenneth I. Strauss, Mary F. Barbe, Renee Marshall Demarest, Ramesh Raghupathi, Samir Mehta, Raj K. Narayan
Prolonged Cyclooxygenase-2 Induction In Neurons And Glia Following Traumatic Brain Injury In The Rat, Kenneth I. Strauss, Mary F. Barbe, Renee Marshall Demarest, Ramesh Raghupathi, Samir Mehta, Raj K. Narayan
Rowan-Virtua School of Osteopathic Medicine Departmental Research
Cyclooxygenase-2 (COX2) is a primary inflammatory mediator that converts arachidonic acid into precursors of vasoactive prostaglandins, producing reactive oxygen species in the process. Under normal conditions COX2 is not detectable, except at low abundance in the brain. This study demonstrates a distinctive pattern of COX2 increases in the brain over time following traumatic brain injury (TBI). Quantitative lysate ribonuclease protection assays indicate acute and sustained increases in COX2 mRNA in two rat models of TBI. In the lateral fluid percussion model, COX2 mRNA is significantly elevated (>twofold, p < 0.05, Dunnett) at 1 day postinjury in the injured cortex and bilaterally in the hippocampus, compared to sham-injured controls. In the lateral cortical impact model (LCI), COX2 mRNA peaks around 6 h postinjury in the ipsilateral cerebral cortex (fivefold induction, p < 0.05, Dunnett) and in the ipsilateral and contralateral hippocampus (two- and six-fold induction, respectively, p < 0.05, Dunnett). Increases are sustained out to 3 days postinjury in the injured cortex in both models. Further analyses use the LCI model to evaluate COX2 induction. Immunoblot analyses confirm increased levels of COX2 protein in the cortex and hippocampus. Profound increases in COX2 protein are observed in the cortex at 1-3 days, that return to sham levels by 7 days postinjury (p < 0.05, Dunnett). The cellular pattern of COX2 induction following TBI has been characterized using immunohistochemistry. COX2-immunoreactivity (-ir) rises acutely (cell numbers and intensity) and remains elevated for several days following TBI. Increases in COX2-ir colocalize with neurons (MAP2-ir) and glia (GFAP-ir). Increases in COX2-ir are observed in cerebral cortex and hippocampus, ipsilateral and contralateral to injury as early as 2 h postinjury. Neurons in the ipsilateral parietal, perirhinal and piriform cortex become intensely COX2-ir from 2 h to at least 3 days postinjury. In agreement with the mRNA and immunoblot results, COX2-ir appears greatest in the contralateral hippocampus. Hippocampal COX2-ir progresses from the pyramidal cell layer of the CA1 and CA2 region at 2 h, to the CA3 pyramidal cells and dentate polymorphic and granule cell layers by 24 h postinjury. These increases are distinct from those observed following inflammatory challenge, and correspond to brain areas previously identified with the neurological and cognitive deficits associated with TBI. While COX2 induction following TBI may result in selective beneficial responses, chronic COX2 production may contribute to free radical mediated cellular damage, vascular dysfunction, and alterations in cellular metabolism. These may cause secondary injuries to the brain that promote neuropathology and worsen behavioral outcome.
N-Methyl-D-Aspartate Receptor Subunit Nr2b Is Widely Expressed Throughout The Rat Diencephalon: An Immunohistochemical Study, Arshad Khan, B. Stanley, Lisa Bozzetti, Christina Chin, Cyndi Stivers, Margarita Curras-Collazo
N-Methyl-D-Aspartate Receptor Subunit Nr2b Is Widely Expressed Throughout The Rat Diencephalon: An Immunohistochemical Study, Arshad Khan, B. Stanley, Lisa Bozzetti, Christina Chin, Cyndi Stivers, Margarita Curras-Collazo
Selected Works Temporary Series
No abstract provided.
N-Methyl-D-Aspartate Receptor Subunit Nr2b Is Widely Expressed Throughout The Rat Diencephalon: An Immunohistochemical Study, Khan, B. Stanley, Lisa Bozzetti, Christina Chin, Cyndi Stivers, Margarita Curras-Collazo
N-Methyl-D-Aspartate Receptor Subunit Nr2b Is Widely Expressed Throughout The Rat Diencephalon: An Immunohistochemical Study, Khan, B. Stanley, Lisa Bozzetti, Christina Chin, Cyndi Stivers, Margarita Curras-Collazo
Departmental Papers (Biology)
No abstract provided.
Lateral Hypothalamic Nmda Receptor Subunits Nr2a And/Or Nr2b Mediate Eating: Immunochemical/Behavioral Evidence, Arshad Khan, Margarita Curras, Jennifer Dao, Faizi Jamal, Rishi Goel, Elizabeth Gillard, Stefany Wolfsohn, B. Stanley
Lateral Hypothalamic Nmda Receptor Subunits Nr2a And/Or Nr2b Mediate Eating: Immunochemical/Behavioral Evidence, Arshad Khan, Margarita Curras, Jennifer Dao, Faizi Jamal, Rishi Goel, Elizabeth Gillard, Stefany Wolfsohn, B. Stanley
Selected Works Temporary Series
No abstract provided.
Lateral Hypothalamic Nmda Receptor Subunits Nr2a And/Or Nr2b Mediate Eating: Immunochemical/Behavioral Evidence, Khan, Margarita Curras, Jennifer Dao, Faizi Jamal, Rishi Goel, Elizabeth Gillard, Stefany Wolfsohn, B. Stanley
Lateral Hypothalamic Nmda Receptor Subunits Nr2a And/Or Nr2b Mediate Eating: Immunochemical/Behavioral Evidence, Khan, Margarita Curras, Jennifer Dao, Faizi Jamal, Rishi Goel, Elizabeth Gillard, Stefany Wolfsohn, B. Stanley
Departmental Papers (Biology)
No abstract provided.
The Second Messenger Camp Elicits Eating By An Anatomically Specific Action In The Perifornical Hypothalamus, Elizabeth Gillard, Arshad Khan, Rickinder Grewal, Bara Mouradi, Stefany Wolfsohn, B. Stanley
The Second Messenger Camp Elicits Eating By An Anatomically Specific Action In The Perifornical Hypothalamus, Elizabeth Gillard, Arshad Khan, Rickinder Grewal, Bara Mouradi, Stefany Wolfsohn, B. Stanley
Selected Works Temporary Series
No abstract provided.
The Second Messenger Camp Elicits Eating By An Anatomically Specific Action In The Perifornical Hypothalamus, Gillard, Arshad Khan, Rickinder Grewal, Bara Mouradi, Stefany Wolfsohn, B. Stanley
The Second Messenger Camp Elicits Eating By An Anatomically Specific Action In The Perifornical Hypothalamus, Gillard, Arshad Khan, Rickinder Grewal, Bara Mouradi, Stefany Wolfsohn, B. Stanley
Departmental Papers (Biology)
No abstract provided.
Eating Induced By Perifornical Camp Is Behaviorally Selective And Involves Protein Kinase Activity, Elizabeth Gillard, Arshad Khan, Bara Mouradi, Omkar Nalamwar, B. Stanley
Eating Induced By Perifornical Camp Is Behaviorally Selective And Involves Protein Kinase Activity, Elizabeth Gillard, Arshad Khan, Bara Mouradi, Omkar Nalamwar, B. Stanley
Selected Works Temporary Series
No abstract provided.
Eating Induced By Perifornical Camp Is Behaviorally Selective And Involves Protein Kinase Activity, Gillard, Arshad Khan, Bara Mouradi, Omkar Nalamwar, B. Stanley
Eating Induced By Perifornical Camp Is Behaviorally Selective And Involves Protein Kinase Activity, Gillard, Arshad Khan, Bara Mouradi, Omkar Nalamwar, B. Stanley
Departmental Papers (Biology)
No abstract provided.