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Articles 61 - 81 of 81
Full-Text Articles in Cognitive Neuroscience
Insect Sentience And The Rise Of A New Inclusive Ethics, David Baracchi, Luigi Baciadonna
Insect Sentience And The Rise Of A New Inclusive Ethics, David Baracchi, Luigi Baciadonna
Animal Sentience
Welfare protections for vertebrates are grounded in the belief that vertebrates are sentient and capable of feeling whereas invertebrates are not. We agree with Mikhalevich & Powell that the exclusion of small-brained invertebrates from bioethics is not warranted by the current state of the scientific evidence. The choice to promote protection for certain invertebrates should be based on the Animal Sentience Precautionary Principle (ASPP). This principle should not prevent us from conducting experimental research with non-human animals to advance knowledge. However, we believe that it is important to outline practical guidelines to manage the wellbeing of invertebrates, while accumulating further …
Comparative Cognition And Nonhuman Individuality, Catia Correia Caeiro
Comparative Cognition And Nonhuman Individuality, Catia Correia Caeiro
Animal Sentience
Commentators Washington (2019) and Tiffin (2019) point out that the individual vs. collective dichotomy is much more complex than what is considered in the target article. This commentary will focus on why individuals are more important than collectives. Species differences in cognition and emotional processes and individuals’ feelings and experiences need to be taken into account.
Whether Invertebrates Are Sentient Matters To Bioethics And Science Policy, Michael L. Woodruff
Whether Invertebrates Are Sentient Matters To Bioethics And Science Policy, Michael L. Woodruff
Animal Sentience
Mikhalevich & Powell provide convincing empirical evidence that at least some invertebrates are sentient and hence should be granted moral status. I agree and argue that functional markers should be the primary indicators of sentience. Neuroanatomical homologies provide only secondary evidence. Consensus regarding the validity of these functional markers will be difficult to achieve. To be effective in practice, functional markers of sentience will have to be tested and accepted species by species to overcome the implicit biases against extending moral status to invertebrates.
Affective Sentience And Moral Protection, Russell Powell, Irina Mikhalevich
Affective Sentience And Moral Protection, Russell Powell, Irina Mikhalevich
Animal Sentience
We have structured our response according to five questions arising from the commentaries: (i) What is sentience? (ii) Is sentience a necessary or sufficient condition for moral standing? (iii) What methods should guide comparative cognitive research in general, and specifically in studying invertebrates? (iv) How should we balance scientific uncertainty and moral risk? (v) What practical strategies can help reduce biases and morally dismissive attitudes toward invertebrates?
Tribal Brains In The Global Village: Deeper Roots Of The Pandemic, Robert Gerlai
Tribal Brains In The Global Village: Deeper Roots Of The Pandemic, Robert Gerlai
Animal Sentience
I briefly recap the messages of the target article by Wiebers & Feigin (2020) and the accompanying peer commentaries about what we learn from the COVID-19 pandemic. Using the rapid evolution of viruses as an example of the importance of prevention, I explore why it is difficult for our species to foresee and prevent unintended global changes resulting from human activity. I end with a discussion about the long-term future, the ultimate problem inherent in our current mindset and the structure of our economy: growth.
Barrels Xxxii Meeting Report: Whiskers In The Windy City, Giuseppe Cataldo, Chia-Chien Chen, Alicia C. Barrientos, Joshua C. Brumberg
Barrels Xxxii Meeting Report: Whiskers In The Windy City, Giuseppe Cataldo, Chia-Chien Chen, Alicia C. Barrientos, Joshua C. Brumberg
Publications and Research
The 32nd Annual Barrels meeting was hosted at the Northwestern University Feinberg School of Medicine in Chicago, Illinois on October 17th and 18th, 2019. The annual meeting brings together researchers who utilize the rodent whisker-to-barrel system as a means to understand cortical function and development. This year’s meeting focused on social behaviors, development and cerebellar functions within the barrel system and beyond.
Can Human Neurological Tests Of Consciousness Be Applied To Octopus?, Benedetta Cecconi, Jitka Annen, Steven Laureys
Can Human Neurological Tests Of Consciousness Be Applied To Octopus?, Benedetta Cecconi, Jitka Annen, Steven Laureys
Animal Sentience
If the anatomy, physiology and behaviour of a species differ substantially from our own, can we infer that the species is unconscious? In the daily clinical care of patients with disorders of consciousness we face many similar challenges: our current approach with these patients - a combination of behavioural and brain imaging-based assessments - might also be a viable route to investigating octopus consciousness.
Ideology And Predictive Processing: Coordination, Bias, And Polarization In Socially Constrained Error Minimization, Nathan E. Wheeler, Suraiya Allidina, Elizabeth U. Long, Stephen P. Schneider, Ingrid J. Haas, William A. Cunningham
Ideology And Predictive Processing: Coordination, Bias, And Polarization In Socially Constrained Error Minimization, Nathan E. Wheeler, Suraiya Allidina, Elizabeth U. Long, Stephen P. Schneider, Ingrid J. Haas, William A. Cunningham
Department of Political Science: Faculty Publications
Recent models of cognition suggest that the brain may implement predictive processing, in which top-down expectations constrain incoming sensory data. In this perspective, expectations are updated (error minimization) only if sensory data sufficiently deviate from these expectations (prediction error). Although originally applied to perception, predictive processing is thought to generally characterize cognitive architecture, including the social cognitive processes involved in ideological thinking. Scaling up these simple computational principles to the social sphere outlines a path by which group members may adopt shared ideologies and beliefs to predict behavior and cooperate with each other. Because ideological judgments are of specific interest …
Do Arthropods Respond To Noxious Stimuli Purely By Reflex?, Robert W. Elwood
Do Arthropods Respond To Noxious Stimuli Purely By Reflex?, Robert W. Elwood
Animal Sentience
Mikhalevich & Powell (2020) argue that it is wrong to dismiss the idea of sentience in invertebrates. Here, I expand on the evidence for crustaceans responding to noxious stimuli in ways that are not explained by mere reflexes, and that are consistent with pain. I consider the idea that male praying mantids must not feel pain because they may continue to mate whilst being consumed by the female. I finish with thoughts about the idea that because robots may be constructed to act as if they experience pain, the argument that animals might experience pain is diminished.
Mechanisms Of Value-Biased Prioritization In Fast Sensorimotor Decision Making, Kivilcim Afacan-Seref
Mechanisms Of Value-Biased Prioritization In Fast Sensorimotor Decision Making, Kivilcim Afacan-Seref
Dissertations and Theses
In dynamic environments, split-second sensorimotor decisions must be prioritized according to potential payoffs to maximize overall rewards. The impact of relative value on deliberative perceptual judgments has been examined extensively, but relatively little is known about value-biasing mechanisms in the common situation where physical evidence is strong but the time to act is severely limited. This research examines the behavioral and electrophysiological indices of how value biases split-second perceptual decisions and the possible mechanisms underlying the process. In prominent decision models, a noisy but statistically stationary representation of sensory evidence is integrated over time to an action-triggering bound, and value-biases …
Attention Strongly Modulates Reliability Of Neural Response To Naturalistic Narrative Stimuli, Jason Ki
Attention Strongly Modulates Reliability Of Neural Response To Naturalistic Narrative Stimuli, Jason Ki
Dissertations and Theses
Attentional engagement is a major determinant of how effectively we gather information through our senses. Alongside the sheer growth in the amount and variety of information content we are presented with through modern media, there is increased variability in the degree to which we ‘absorb’ that information. Traditional research on attention has illuminated the basic principles of sensory selection to isolated features or locations, but it provides little insight into the neural underpinnings of our attentional engagement with modern naturalistic content. Here, we show in human subjects that the reliability of an individual's neural responses with respect to a larger …
Problems With Basing Insect Ethics On Individuals’ Welfare, Susana Monsó, Antonio J. Osuna-Mascaró
Problems With Basing Insect Ethics On Individuals’ Welfare, Susana Monsó, Antonio J. Osuna-Mascaró
Animal Sentience
In their target article, Mikhalevich & Powell (M&P) argue that we should extend moral protection to arthropods. In this commentary, we show that there are some unforeseen obstacles to applying the sort of individualistic welfare-based ethics that M&P have in mind to certain arthropods, namely, insects. These obstacles have to do with the fact that there are often many more individuals involved in our dealings with insects than our ethical theories anticipate, and also with the fact that, in some sense, some insects count as more than an individual and, in another sense, they sometimes count as less than an …
Lessons From Miniature Brains: Cognition Cheap, Memory Expensive (Sentience Linked To Active Movement?), Giorgio Vallortigara
Lessons From Miniature Brains: Cognition Cheap, Memory Expensive (Sentience Linked To Active Movement?), Giorgio Vallortigara
Animal Sentience
Studies on invertebrate minds suggest that the neural machinery for basic cognition is cheap, and that bigger brains are probably associated with greater memory storage rather than more advanced cognition. Sentience may be linked to feedforward mechanisms (Reafferenzprinzip) that allow organisms with active movement to distinguish active and passive sensing. Invertebrates may offer special opportunities for testing these hypotheses.
Alzheimer's Disease Drug Development Pipeline: 2020, Jeffrey Cummings, Garam Lee, Aaron Ritter, Marwan Sabbagh, Kate Zhong
Alzheimer's Disease Drug Development Pipeline: 2020, Jeffrey Cummings, Garam Lee, Aaron Ritter, Marwan Sabbagh, Kate Zhong
School of Medicine Faculty Research
© 2020 The Authors. Alzheimer's & Dementia: Translational Research & Clinical Interventions published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association. Introduction: Alzheimer's disease (AD) is a growing public health concern affecting millions of patients worldwide and costing billions of dollars annually. We review the pipeline of drugs and biologics in clinical trials for the treatment of AD. We use the Common Alzheimer's and Related Dementias Research Ontology (CADRO) to classify treatment targets and mechanisms of action. We review our annual pipeline reports for the past 5 years to provide longitudinal insight into clinical trials and drug development for …
Open Peer Commentary To “Failure To Demonstrate Efficacy Of Aducanumab: An Analysis Of The Emrge And Engage Trials As Reported By Biogen December 2019”, Marwan Noel Sabbagh, Jeffrey Cummings
Open Peer Commentary To “Failure To Demonstrate Efficacy Of Aducanumab: An Analysis Of The Emrge And Engage Trials As Reported By Biogen December 2019”, Marwan Noel Sabbagh, Jeffrey Cummings
School of Medicine Faculty Research
No abstract provided.
Image And Video-Based Autism Spectrum Disorder Detection Via Deep Learning, Mindi Ruan
Image And Video-Based Autism Spectrum Disorder Detection Via Deep Learning, Mindi Ruan
Graduate Theses, Dissertations, and Problem Reports (ETD)
People with Autism Spectrum Disorder (ASD) show atypical attention to social stimuli and aberrant gaze when viewing images of the physical world. However, it is unknown how they perceive the world from a first-person perspective. In this study, we used machine learning to classify photos taken in three different categories (people, indoors, and outdoors) as either having been taken by individuals with ASD or by peers without ASD. Our classifier effectively discriminated photos from all three categories but was particularly successful at classifying photos of people with >80% accuracy. Importantly, the visualization of our model revealed critical features that led …
The Interplay Of Progestins, Matrix Metalloproteinases, And The Aging Brain, Keyana Nicole Porter
The Interplay Of Progestins, Matrix Metalloproteinases, And The Aging Brain, Keyana Nicole Porter
Graduate Theses, Dissertations, and Problem Reports (ETD)
Progestins are synthetic hormones that are designed to mimic the biological actions of progesterone. They, however, possess other pharmacological actions and properties, in addition to their progestational activities. Medroxyprogesterone Acetate (MPA) is a progestin used globally in the hormonal contraceptive, Depo Provera®, by women in their reproductive prime and is a major compound found in hormone therapy (HT) formulations used by menopausal women. MPA is used by approximately 1 in 5 adolescents and adult women in the United States who are sexually active. Globally, nearly 48 million women utilize injectable contraceptives to prevent pregnancy, with most users utilizing MPA as …
Ethical Considerations For Invertebrates, Scarlett R. Howard, Matthew R.E. Symonds
Ethical Considerations For Invertebrates, Scarlett R. Howard, Matthew R.E. Symonds
Animal Sentience
Mikhalevich & Powell (2020) have built on the discussion about which species deserve inclusion in animal ethics and welfare considerations. Here, we raise questions concerning the assessment criteria. We ask how to assess different species for their ability to fulfill the criteria, which criteria are most important, how we quantify them (absolute or on a continuum), and how non-animals such as fungi and plants fit into this paradigm.
What Makes An Image Memorable? Effects Of Encoding On The Mechanism Of Recognition, Asiya Gul
What Makes An Image Memorable? Effects Of Encoding On The Mechanism Of Recognition, Asiya Gul
Theses and Dissertations (Comprehensive)
Memory is undoubtedly one of the most important processes of human cognition. A long line of research suggests that recognition relies on the assessment of two explicit memory phenomena: familiarity and recollection. Researchers who support the Dual Process Signal Detection (DPSD) model of recognition memory link the FN400 component (a negative ERP deflection peaking around 400 ms at frontal electrodes) with familiarity; however, it is currently unclear whether the FN400 reflects familiarity or implicit memory. Three event-related potentials (ERP) studies were conducted to determine whether implicit memory plays a role in setting up encoding strategies, and how these encoding strategies …
Exploring Eight-Armed Intelligence Through Film, Tierney M. Thys
Exploring Eight-Armed Intelligence Through Film, Tierney M. Thys
Animal Sentience
Mather (2019) provides a rich overview of the elements underlying octopus cognition and behavioral flexibility. Recently, two remarkable natural history films, My Octopus Teacher and The Octopus in My House have explored intimate human-octopus relationships with a wild (Octopus vulgaris) and a captive octopus (Octopus cyanea) respectively. Both films show rare behaviors that offer observations to test new hypotheses as well as a novel perspective on our own human relationships and place within the natural world. An interview with filmmaker Craig Foster from My Octopus Teacher reveals the profound and transformative power of forming a trusting …
Impact Of Uk Sport Fishing On Fish Welfare And Conservation, Tim Q. Holmes
Impact Of Uk Sport Fishing On Fish Welfare And Conservation, Tim Q. Holmes
Animal Sentience
Sport fishing or angling is the capture of fish for recreation or competition, i.e., for entertainment. Contrary to the claims of Key (2016), there is good evidence that fish feel pain and have the capacity for self-awareness (Sneddon et al., 2018; Woodruff, 2017). Wild fish experience a variety of adverse conditions in nature that can harm their welfare, but this does not justify humans intentionally inflicting such conditions on fish solely for our pleasure. This commentary summarises the many ways fish suffer harm to their welfare as a result of sport fishing. There are also discussions on associated activities that …