Cognitive Neuroscience Commons^™

Neural Substrates Of Sound–Touch Synesthesia After A Thalamic Lesion, Michael S. Beauchamp, Tony Ro

Publications and Research

Neural plasticity induced by stroke can mediate positive outcomes, such as recovery of function, but can also result in the formation of abnormal connections with negative consequences for perception and cognition. In three experiments using blood-oxygen level dependent (BOLD) functional magnetic resonance imaging, we examined the neural substrates of acquired auditory-tactile synesthesia, in which certain sounds can produce an intense somatosensory tingling sensation in a patient with a thalamic lesion. Compared with nine normal controls, the first experiment showed that the patient had a threefold greater BOLD response to sounds in the parietal operculum, the location of secondary somatosensory cortex. …

Medial Temporal Lobe Bold Activity At Rest Predicts Individual Differences In Memory Ability In Hhealthy Young Adults, Gagan S. Wig, Scott T. Grafton, Kathryn E. Demos, George L. Wolford, Steven E. Petersen, William M. Kelley

Dartmouth Scholarship

Human beings differ in their ability to form and retrieve lasting long-term memories. To explore the source of these individual differences, we used functional magnetic resonance imaging to measure blood-oxygen-level-dependent (BOLD) activity in healthy young adults (n = 50) during periods of resting fixation that were interleaved with periods of simple cognitive tasks. We report that medial temporal lobe BOLD activity during periods of rest predicts individual differences in memory ability. Specifically, individuals who exhibited greater magnitudes of task-induced deactivations in medial temporal lobe BOLD signal (as compared to periods of rest) demonstrated superior memory during offline testing. This relationship …

Examining Neurophysiological Evidence Of Age-Related Interactions Of Sensory And Cognitive Processes During Speech Processing, Cady Kristen Block

Psychology Theses & Dissertations

The present study sought to examine the contribution of sensory and cognitive factors on speech processing as evidenced by ERP measures and to find support for the Sensory Cognitive Interaction Theory (SCIT) and the Effortfulness Hypothesis in that older adults. who experience sensory deficits with normal aging. must put forth increased effort during early sensory stages of speech processing that may compromise subsequent semantic performance and recall of information. In the present investigation. younger and older adults performed a sentence verification task at low and high presentation levels (PL). Accuracy and response time to sentence verifications were assessed along with …

Factors That Affect Performance On Executive Functioning After Coronary Artery Bypass Grafting, Sapna Mahesh Patel

Loma Linda University Electronic Theses, Dissertations & Projects

Research suggests that individuals who undergo coronary artery bypass grafting (CABG) experience declines in neuropsychological functioning post-operatively. This decline has been observed in up to 80% of patients early after surgery, and in up to 30% of patients after six months. Many studies have examined the potential effects of CABG on neuropsychological functioning in general, and numerous studies have found that executive functions are impaired in particular. However, none have examined what factors contribute to observed executive dysfunction after CABG. This study investigated the role of memory functions on executive functions in a selected sample of patients undergoing CABG. This …

A Songbird Forebrain Area Potentially Involved In Auditory Discrimination And Memory Formation, Raphael Pinaud, Thomas A. Terleph

Biology Faculty Publications

Songbirds rely on auditory processing of natural communication signals for a number of social behaviors, including mate selection, individual recognition and the rare behavior of vocal learning - the ability to learn vocalizations through imitation of an adult model, rather than by instinct. Like mammals, songbirds possess a set of interconnected ascending and descending auditory brain pathways that process acoustic information and that are presumably involved in the perceptual processing of vocal communication signals. Most auditory areas studied to date are located in the caudomedial forebrain of the songbird and include the thalamo-recipient field L (subfields L1, L2 and L3), …

Psycho-Social Effects Of A Brain-Training Program Among Healthy Older Adults, Desma Hurley, M. Jean Turner, William C. Bailey

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Grounded in cognitive neuroscience and social exchange theory, this research evaluated the relationship between changes in cognitive functioning and two psycho-social dimensions of life among healthy adults over the age of 70 (N=12). Specific psycho-social dimensions examined were social interaction and depression. Six females and six males participated in the study. All were white, college-educated individuals residing in a life-care residential retirement community. The participants used the Posit Science® Brain Fitness Program™, an auditory-based computer training program that improves memory and speed of processing, for forty hours over an eight-week period. Pre- and post-tests related to social interaction and depressive …

Neuroimaging And Capital Punishment, O. Carter Snead

Journal Articles

Can brain scans be used to determine whether a person is inclined toward criminality or violent behavior?

This question, asked by Senator Joseph Biden of Delaware at the hearing considering the nomination of John Roberts to be Chief Justice of the United States, illustrates the extent to which cognitive neuroscience - increasingly augmented by the growing powers of neuroimaging, the use of various technologies to directly or indirectly observe the structure and function of the brain - has captured the imagination of those who make, enforce, interpret, and study the law.

The attraction of the legal community to cognitive neuroscience …

Melody Recognition At Fast And Slow Tempos: Effects Of Age, Experience, And Familiarity, W. Jay Dowling, James C. Bartlett, Andrea R. Halpern, Melinda W. Andrews

Faculty Journal Articles

Eighty-one listeners defined by three age ranges (18–30, 31–59, and over 60 years) and three levels of musical experience performed an immediate recognition task requiring the detection of alterations in melodies. On each trial, a brief melody was presented, followed 5 sec later by a test stimulus that either was identical to the target or had two pitches changed, for a same–different judgment. Each melody pair was presented at 0.6 note/sec, 3.0 notes/sec, or 6.0 notes/sec. Performance was better with familiar melodies than with unfamiliar melodies. Overall performance declined slightly with age and improved substantially with increasing experience, in agreement …

Effects Of Timbre And Tempo Change On Memory For Music, Andrea R. Halpern, Daniel Mullensiefen

Faculty Journal Articles

We investigated the effects of different encoding tasks and of manipulations of two supposedly surface parameters of music on implicit and explicit memory for tunes. In two experiments, participants were first asked to either categorize instrument or judge familiarity of 40 unfamiliar short tunes. Subsequently, participants were asked to give explicit and implicit memory ratings for a list of 80 tunes, which included 40 previously heard. Half of the 40 previously heard tunes differed in timbre (Experiment 1) or tempo (Experiment 2) in comparison with the first exposure. A third experiment compared similarity ratings of the tunes that varied in …