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Articles 61 - 63 of 63
Full-Text Articles in Cognitive Neuroscience
Acc Theta Improves Hippocampal Contextual Processing During Remote Recall, Ryan A. Wirt, James M. Hyman
Acc Theta Improves Hippocampal Contextual Processing During Remote Recall, Ryan A. Wirt, James M. Hyman
Psychology Faculty Research
Consolidation studies show that, over time, memory recall becomes independent of the medial temporal lobes. Multiple lines of research show that the medial frontal cortex, including the anterior cingulate cortex (ACC), is involved with contextual information processing and remote recall. We hypothesize that interactions between the ACC and hippocampal area CA1 will change as memories became more remote. Animals are re-exposed to multiple environments at different retention intervals. During remote recall, ACC-CA1 theta coherence increases, with the ACC leading area CA1. ACC theta regulates unit spike timing, gamma oscillations, and ensemble and single-neuron information coding in CA1. Over the course …
Environmental Effects On Drosophila Brain Development And Learning, Xia Wang, Amei Amei, J. Steven De Belle, Stephen P. Roberts
Environmental Effects On Drosophila Brain Development And Learning, Xia Wang, Amei Amei, J. Steven De Belle, Stephen P. Roberts
School of Medicine Faculty Research
Brain development and behavior are sensitive to a variety of environmental influences including social interactions and physicochemical stressors. Sensory input in situ is a mosaic of both enrichment and stress, yet little is known about how multiple environmental factors interact to affect brain anatomical structures, circuits and cognitive function. In this study, we addressed these issues by testing the individual and combined effects of sub-adult thermal stress, larval density and early-adult living spatial enrichment on brain anatomy and olfactory associative learning in adult Drosophila melanogaster. In response to heat stress, the mushroom bodies (MBs) were the most volumetrically impaired among …
A Longitudinal Study Of Neurocognitive Deficits And Functional Outcome In Bipolar Disorder, Brian D. Leany
A Longitudinal Study Of Neurocognitive Deficits And Functional Outcome In Bipolar Disorder, Brian D. Leany
UNLV Theses, Dissertations, Professional Papers, and Capstones
Bipolar disorder is an affective disorder that, in addition to being characterized by depressive and expansive mood symptoms, often presents with neuropsychological deficits. Bipolar disorder not only impairs an individual’s cognitive abilities, but these cognitive impairments may also impact day-to-day activities causing functional impairment. In other psychiatric disorders such as schizophrenia, it has been shown that the neuropsychological deficits are predictive of poor, long term treatment outcome and functioning. However, while bipolar disorder affects nearly 1 - 2% of the U.S. population (Keck, McElroy, & Arnold, 2001), little is known about the extent that neurocognitive deficits may play in the …