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Dopamine

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Articles 31 - 36 of 36

Full-Text Articles in Behavioral Neurobiology

Role Of Dopamine In Impulse Control, Paul Rafael Sabandal ^, Young-Cho Kim, Kyung-An Han * Jul 2011

Role Of Dopamine In Impulse Control, Paul Rafael Sabandal ^, Young-Cho Kim, Kyung-An Han *

COURI Symposium Abstracts, Summer 2011

No abstract provided.

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Dysfunctional Play And Dopamine Physiology In The Fischer 344 Rat, Stephen M. Siviy, Cynthia A. Crawford, Garnik Akopian, John P. Walsh Jul 2011

Dysfunctional Play And Dopamine Physiology In The Fischer 344 Rat, Stephen M. Siviy, Cynthia A. Crawford, Garnik Akopian, John P. Walsh

Psychology Faculty Publications

Juvenile Fischer 344 rats are known to be less playful than other inbred strains, although the neurobiological substrate(s) responsible for this phenotype is uncertain. In the present study, Fischer 344 rats were compared to the commonly used outbred Sprague-Dawley strain on several behavioral and physiological parameters in order to ascertain whether the lack of play may be related to compromised activity of brain dopamine (DA) systems. As expected, Fischer 344 rats were far less playful than Sprague-Dawley rats, with Fischer 344 rats less likely to initiate playful contacts with a playful partner and less likely to respond playfully to these …

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Dopamine’S Role In Ethanol Induced Behavioral Disinhibition, Erick Saldes^, Kyung-An Han* Apr 2011

Dopamine’S Role In Ethanol Induced Behavioral Disinhibition, Erick Saldes^, Kyung-An Han*

COURI Symposium Abstracts, Spring 2011

Ethanol is commonly associated with disinhibited motor and sexual behaviors in humans. Dopamine and serotonin are implicated in these processes since they regulate reward, motivation, aggression, movement control, and sexual behavior. Disinhibited behavior such as impulsivity (loss of impulse control) is also related to addiction. The major goal of this study is to identify the role of dopamine in disinhibited behavior using the genetic model system, Drosophila melanogaster.  For this task we developed a novel apparatus called Flypub. It is a plastic chamber with a clear top for recording and monitoring fly behavior before, during, and after ethanol exposure. …

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The Role Of Dopamine In Operant Learning And Memory, Jennifer Leigh Johnson Jan 2011

The Role Of Dopamine In Operant Learning And Memory, Jennifer Leigh Johnson

Open Access Theses & Dissertations

Dopamine is a neurotransmitter that regulates many physiological processes including reward, motivation, movement, learning and memory, and reinforcement. The cognitive processes in which one associates a specific action or behavior with a positive or negative consequence is referred to as operant learning, and is a robust occurrence in everyday life. It is also believed to play a significant role in the development of drug addiction and has been shown that increased levels of dopamine are associated with the intake of addictive drugs such as cocaine and alcohol; however, the underlying cellular mechanisms of this learned behavior are not well understood. …

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Role Of Dopamine Of Nucleus Accumbens In Behavioral Sensitization To Methylphenidate, Sheshali J. Wanchoo May 2010

Role Of Dopamine Of Nucleus Accumbens In Behavioral Sensitization To Methylphenidate, Sheshali J. Wanchoo

Dissertations and Theses (Open Access)

Behavioral sensitization is defined as the subsequent augmentation of the locomotor response to a drug following repeated administrations of the drug. It is believed to occur due to alterations in the motive circuit in the brain by stressors, central nervous system stimulants, and similar stimuli. The motive circuit (or mesocorticolimbic system) consists of several interconnected nuclei that determine the behavioral response to significant biological stimuli. A final target of the mesocorticolimbic system is the nucleus accumbens (NAc), which is a key structure linking motivation and action. In particular, the dopaminergic innervations of the Nac are considered to be essential in …

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Characterization Of The Behavioral And Neurochemical Effects Of Nicotine Withdrawal In Adolescent And Adult Rats., Luis Alberto Natividad Jan 2009

Characterization Of The Behavioral And Neurochemical Effects Of Nicotine Withdrawal In Adolescent And Adult Rats., Luis Alberto Natividad

Open Access Theses & Dissertations

Previous studies have demonstrated that the behavioral effects of nicotine withdrawal are lower in adolescent versus adult rats. However, the neurochemical mechanisms that mediate these developmental differences are presently unclear. Much work has shown that nicotine reward is mediated via enhanced dopamine neurotransmission in the mesolimbic pathway which originates in the ventral tegmental area (VTA) and terminates in several forebrain structures including the nucleus accumbens (NAcc). More recently, studies have shown that nicotine withdrawal produces a decrease in NAcc dopamine transmission, an effect that is believed to serve as a neurochemical marker of withdrawal in adult rodents. The goal of …

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