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Articles 1 - 12 of 12
Full-Text Articles in Behavioral Neurobiology
An Analysis Of Developmental Changes In Twitch Patterning During Rem Sleep, Claire Wolfer-Jenkins, Taylor Svoboda
An Analysis Of Developmental Changes In Twitch Patterning During Rem Sleep, Claire Wolfer-Jenkins, Taylor Svoboda
The Journal of Purdue Undergraduate Research
No abstract provided.
Effects Of Alcohol Exposure On Recognition Memory And Marble-Burying Tasks In Male And Female Aged Mice, Roma Kamat, Tori Burke
Effects Of Alcohol Exposure On Recognition Memory And Marble-Burying Tasks In Male And Female Aged Mice, Roma Kamat, Tori Burke
The Journal of Purdue Undergraduate Research
Alcohol consumption in aging humans is a risk factor for cognitive impairment. This experiment assessed the effects of binge-like alcohol drinking in aged mice on memory (using the object recognition memory [ORM] task) and on anxiety-and compulsive-like behavior (using the marble-burying task). Subjects were 8 female and 10 male mice, 14–15 months old, selectively bred for low alcohol preference (LAP). Mice consumed either tap water or a 20% alcohol (v/v) solution in tap water through a drinking in the dark (DID) procedure for 4 consecutive days per week, for 3 consecutive weeks. One and 11 days after DID, mice completed …
Perceptograms And Cortical Models For Amblyopic Form Distortions, Akihito Maruya, Farzaneh Olianezhad, Jingyun Wang, Jose-Manuel Alonso, Qasim Zaidi
Perceptograms And Cortical Models For Amblyopic Form Distortions, Akihito Maruya, Farzaneh Olianezhad, Jingyun Wang, Jose-Manuel Alonso, Qasim Zaidi
MODVIS Workshop
No abstract provided.
Local Geometry Of Elementary Visual Computations, Peter Neri
Local Geometry Of Elementary Visual Computations, Peter Neri
MODVIS Workshop
Visual operators (e.g. edge detectors) are classically modelled using small circuits involving canonical computations, such as template-matching and gain control. Circuit models explain many aspects of the empirical descriptors that are used to characterize local visual operators, from sensitivity to classification images. Notwithstanding their utility, these models fail to provide a unified framework encompassing the variety of effects observed experimentally, such as the impact of contrast, SNR, and attention on the above descriptors. My goal is to start with a simple, plausible geometrical representation of the perceptual operation carried out by the observer, and to show that this representation is …
Active Encoding Of Space Through Time, Michele Rucci, Jonathan D. Victor
Active Encoding Of Space Through Time, Michele Rucci, Jonathan D. Victor
MODVIS Workshop
No abstract provided.
Impact Of Adolescent Social Isolation On Adult, Binge-Like Ethanol Consumption And Plasma Corticosterone In High-Alcohol-Preferring Mice, Eva Cullins
The Journal of Purdue Undergraduate Research
Adolescent stress exposure increases the likelihood of alcohol misuse and alcohol use disorder (AUD) in adulthood; however, it is not clear how genetic and environmental factors interact to increase risk. This study examined how adolescent social isolation affects adult binge-like ethanol drinking and levels of the stress hormone corticosterone in male and female mice with a genetic predisposition toward high alcohol preference (HAP). Twenty-eight HAP mice were separated into group-housed (GH) and socially isolated (SI) conditions (n = 13, 13). Binge drinking was assessed using a drinking in the dark (DID) procedure. Blood samples were taken before DID and after …
The Effects Of Adolescent Chronic Mild Stress: In Female Wistar-Kyoto Rats, Anna Hallowell
The Effects Of Adolescent Chronic Mild Stress: In Female Wistar-Kyoto Rats, Anna Hallowell
The Journal of Purdue Undergraduate Research
Despite years of research to understand under-lying mechanisms and develop more effective treatment approaches for mood disorders, numerous challenges exist. Many chronic stress models are used to study mood disorders, how-ever the majority have been established with adult males. This is problematic considering that affective disorders are more common in women, and generally develop during late adolescence. Studies have indicated fundamental behavioral, physiological, and neural differences between males and females in response to the same external stressors, furthering a need to develop sex-specific paradigms to accurately model the etiology of mood disorders in females. The Wistar-Kyoto (WKY) rat strain is …
A Touchscreen Assay To Probe The Role Of The Serotonergic System In Learning And Visual Information Processing, Jeffrey M. Dorsch, Alexandr Pak, Alexander A. Chubykin
A Touchscreen Assay To Probe The Role Of The Serotonergic System In Learning And Visual Information Processing, Jeffrey M. Dorsch, Alexandr Pak, Alexander A. Chubykin
The Summer Undergraduate Research Fellowship (SURF) Symposium
The neurotransmitter serotonin is involved in numerous processes in the brain such as behavior, learning, memory, mood, and neurodevelopment. Serotonin signaling is regulated by the serotonin transporter protein (SERT), which maintains normal serotonin levels. Mutations in the SERT gene are known to correlate with cognitive and behavioral deficits seen in psychiatric disorders, such as anxiety disorders, depression, and autism spectrum disorder. Researchers study these deficits using SERT knockout (KO) mice, a model that lacks functional SERT and displays changes in anxiety, learning, and motivation. We are interested in how the absence of SERT affects visual processing and learning. A popular …
Central And Peripheral Difference In Perceptual Bias In Ambiguous Perception Using Dichoptic Stimuli --- Implications For The Analysis-By-Synthesis Process In Visual Recognition, Li Zhaoping Prof
MODVIS Workshop
No abstract provided.
Comparing Diverse V1 Models On The Same Platform: Virtual V1sion, Cheryl Olman
Comparing Diverse V1 Models On The Same Platform: Virtual V1sion, Cheryl Olman
MODVIS Workshop
No abstract provided.
Behavioral Outputs Of Fragile-X Autistic Mice Exposed To Open-Field, Randomized, Short-Term Visual Stimuli, Nicholas M. Dicola, Alexander A. Chubykin
Behavioral Outputs Of Fragile-X Autistic Mice Exposed To Open-Field, Randomized, Short-Term Visual Stimuli, Nicholas M. Dicola, Alexander A. Chubykin
The Summer Undergraduate Research Fellowship (SURF) Symposium
Animal models of different neurological disorders are required for studying the pathophysiology of these diseases, and for potential development of pharmacological and behavioral treatments. The scientific community often uses mouse models for behavior studies due to their powerful genetic tools and low cost. However, subjective measurement techniques are often used when analyzing mice for behavioral traits which often results in discrepancies in results. An automated tracking software would aim to eliminate these discrepancies and subjective analysis. This lab has developed a software program which offered an ability to automatically collect open-field behavioral data with simultaneous on-line analysis. Python, an open …
Elucidation Of Pharmacologically Manipulated Responding In The Delay Discounting Task In High Alcohol Preferring Mice, Meredith Halcomb
Elucidation Of Pharmacologically Manipulated Responding In The Delay Discounting Task In High Alcohol Preferring Mice, Meredith Halcomb
Open Access Dissertations
Impulsive behavior is the hallmark of many psychopathologies. Uncovering the neurobiological mechanisms driving impulsivity is paramount in the development of through the delay discounting (DD) task in both human and animal models. The present study is an examination of the predictive validity of the two primary types of DD procedures in animals, the Adjusting Amounts (AA) and within session Increasing Delays (ID) tasks. Methods:Subjects were administered either1.25 mg/kg d-amphetamine (AMP), 1.5 g/kg ethanol (EtOH) or saline and tested in either the AA or ID method for 15 days to evaluate drug effects on impulsive behavior. Results: Stimulant administration resulted …