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Articles 61 - 90 of 159
Full-Text Articles in Behavioral Neurobiology
Effects Of Neonatal Hypoxic Ischemic Brain Injury On Spatial Working Memory, Amanda L. Smith
Effects Of Neonatal Hypoxic Ischemic Brain Injury On Spatial Working Memory, Amanda L. Smith
Master's Theses
Children born prematurely or at very low birth weight (VLBW) have an increased risk for hypoxic ischemic brain injury (HI). HI refers to a lack of adequate blood and oxygen flow in the brain. HI can also occur in the term infant due to birth complications such as prolonged labor, placental dysfunction, or cord prolapse. In both populations (though exact patterns of neuropathology vary) brain damage is likely to occur in the form of decreased hippocampal and cortical volume, and enlargement of the ventricles (Kesler et al., 2004, Nagy et al., 2009). Resulting neuropathology can in turn lead to cognitive …
Effect Of Nicotine On Body Composition, Laura O'Dell
Effect Of Nicotine On Body Composition, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Effect Of Nicotine On Body Composition, Laura O'Dell
Effect Of Nicotine On Body Composition, Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
The Effects Of Prenatal Exposure To Altered Melatonin Levels On Hippocampal Gene Expression In The Male Rat, Anna Uehara
The Effects Of Prenatal Exposure To Altered Melatonin Levels On Hippocampal Gene Expression In The Male Rat, Anna Uehara
Honors Theses
The stability of the circadian rhythm for mammals depends on the levels of serotonin and melatonin, neurohormones that signal for lightness and darkness, respectively. Disruption in the stability of neurohormones has been shown to be a critical factor in psychopathological disorders in humans. For example, altering levels of melatonin in utero through administration of melatonin or the melatonin receptor antagonist, luzindole, has been shown to cause changes in developmental growth and adult behavior in the male rat. Analysis of relative adult hippocampal gene expression with RT-PCR revealed differences in ARNTL expression that suggested abnormality in clock gene expression of the …
Empathy-Based Conservation: An Interdisciplinary Approach To Conservation Policy And Decision-Making, Kaitlyn Delashmutt
Empathy-Based Conservation: An Interdisciplinary Approach To Conservation Policy And Decision-Making, Kaitlyn Delashmutt
Department of Environmental Studies: Undergraduate Student Theses
In the late 20th century, neuroscientists in Italy discovered a neuron in the brain capable of mentally mimicking the emotions derived from the actions of others (Rizzolatti and Craighero, 2004). It is the process that makes your elbow ache when someone else knocks their elbow on the counter or the uncontrollable smile that creeps up when someone smiles at you. No questions asked, people intuitively sense what others are feeling. The old school of thought was that humans deduced through logic and reason the actions of others and interpreted the emotions through a rational process (Carew et al, 2008). …
In Search Of The Neurobiological Substrates For Social Playfulness In Mammalian Brains, Stephen M. Siviy, Jaak Panksepp
In Search Of The Neurobiological Substrates For Social Playfulness In Mammalian Brains, Stephen M. Siviy, Jaak Panksepp
Psychology Faculty Publications
Play behavior is a fundamental and intrinsic neurobehavioral process in the mammalian brain. Using rough-and-tumble play in the juvenile rat as a model system to study mammalian playfulness, some of the relevant neurobiological substrates for this behavior have been identified, and in this review this progress. A primary-process executive circuit for play in the rat that includes thalamic intralaminar nuclei, frontal cortex and striatum can be gleaned from these data. Other neural areas that may interact with this putative circuit include amygdala, ventral hypothalamus, periaqueductal gray (PAG), and deep tectum, as well as ascending dopamine systems which participate in all …
Serotonin, Motivation, And Playfulness In The Juvenile Rat, Stephen M. Siviy, Loren M. Deron, Chelsea R. Kasten
Serotonin, Motivation, And Playfulness In The Juvenile Rat, Stephen M. Siviy, Loren M. Deron, Chelsea R. Kasten
Psychology Faculty Publications
The effects of the selective 5HT1A agonist 8-OH-DPAT were assessed on the play behavior of juvenile rats. When both rats of the test pair were comparably motivated to play, the only significant effect of 8-OH-DPAT was for play to be reduced at higher doses. When there was a baseline asymmetry in playful solicitation due to a differential motivation to play and only one rat of the pair was treated, low doses of 8-OH-DPAT resulted in a collapse of asymmetry in playful solicitations. It did not matter whether the rat that was treated initially accounted for more nape contacts or fewer …
Dysfunctional Play And Dopamine Physiology In The Fischer 344 Rat, Stephen M. Siviy, Cynthia A. Crawford, Garnik Akopian, John P. Walsh
Dysfunctional Play And Dopamine Physiology In The Fischer 344 Rat, Stephen M. Siviy, Cynthia A. Crawford, Garnik Akopian, John P. Walsh
Psychology Faculty Publications
Juvenile Fischer 344 rats are known to be less playful than other inbred strains, although the neurobiological substrate(s) responsible for this phenotype is uncertain. In the present study, Fischer 344 rats were compared to the commonly used outbred Sprague-Dawley strain on several behavioral and physiological parameters in order to ascertain whether the lack of play may be related to compromised activity of brain dopamine (DA) systems. As expected, Fischer 344 rats were far less playful than Sprague-Dawley rats, with Fischer 344 rats less likely to initiate playful contacts with a playful partner and less likely to respond playfully to these …
Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell
Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell
Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
Characterizing And Treating The Neuropathology Of Tuberous Sclerosis Complex In The Mouse, Sharon W. Way
Characterizing And Treating The Neuropathology Of Tuberous Sclerosis Complex In The Mouse, Sharon W. Way
Dissertations and Theses (Open Access)
Tuberous sclerosis complex (TSC) is a multisystem, autosomal dominant disorder affecting approximately 1 in 6000 births. Developmental brain abnormalities cause substantial morbidity and mortality and often lead to neurological disease including epilepsy, cognitive disabilities, and autism. TSC is caused by inactivating mutations in either TSC1 or TSC2, whose protein products are known inhibitors of mTORC1, an important kinase regulating translation and cell growth. Nonetheless, neither the pathophysiology of the neurological manifestations of TSC nor the extent of mTORC1 involvement in the development of these lesions is known. Murine models would greatly advance the study of this debilitating disorder. This thesis …
Locus Of Control And The Age Difference In Free Recall From Episodic Memory, Paul Amrhein, Judith K. Bond, Derek Hamilton
Locus Of Control And The Age Difference In Free Recall From Episodic Memory, Paul Amrhein, Judith K. Bond, Derek Hamilton
Department of Psychology Faculty Scholarship and Creative Works
The authors investigated the relation of locus of control (LOC) to age differences in free-recall memory performance. Older and younger participants completed P. C. Duttweiler's (1984) Internal Control Index (ICI) and subsequently performed free-recall memory tasks. Compared with the younger participants, the older participants exhibited poorer recall with more intrusions and uncorrected repetition errors as well as reduced categorical clustering. For the older participants with less internal LOC, recall proportion and item-pair associative recall clustering were lower than for the older participants with more internal LOC. By contrast, the younger participants did not exhibit any LOC effects in their recall …
Effects Of Chlordiazepoxide On Predator Odor-Induced Reductions Of Playfulness In Juvenile Rats, Stephen M. Siviy, Courtney L. Steets, Lauren M. Debrouse
Effects Of Chlordiazepoxide On Predator Odor-Induced Reductions Of Playfulness In Juvenile Rats, Stephen M. Siviy, Courtney L. Steets, Lauren M. Debrouse
Psychology Faculty Publications
The extent to which a non-sedative dose of chlordiazepoxide (CDP) is able to modify the behavioral responses toward a predator odor was assessed in juvenile rats. Play behavior was suppressed and defensive behaviors were enhanced in the presence of a collar previously worn by a cat, when tested 24 hours later in the same context as that where the exposure occurred, and when tested in a context different than that in which the exposure occurred for up to 3 hours after exposure. CDP had no effect on the ability of cat odor to suppress play when rats were tested in …
A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell
A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Pdf Of All O'Dell Manuscripts, Laura O'Dell
Pdf Of All O'Dell Manuscripts, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell
Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell
The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell
The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell
A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell
Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell
Departmental Papers (Psych)
No abstract provided.