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Full-Text Articles in Virology

A Review Of The Molecular Mediators Of Host-Baculovirus Interactions In Lepidoptera, Olivia Crouse Jan 2021

A Review Of The Molecular Mediators Of Host-Baculovirus Interactions In Lepidoptera, Olivia Crouse

Honors Program Theses

Iowa farmlands occupy approximately 85% of its 35.7 million acres, and Iowa leads the United States in corn and soybean production, with an estimated 2.58 billion and 502 million bushels of corn and soybean produced in 2019, respectively. This successful trend in annual yields has span forty plus years and been consequential to the simultaneous implementation of agricultural- and science-based practices. Genetically modified corn and soybean crop varieties express genes from Bacillus thuringiensis (Bt) which encode insecticidal proteins that protect, with high specificity, against insect pests. While researchers continue to study the molecular mechanism(s) of Bt extensively, alternative environmentally safe …


Identification Of Genome-Linked Bacillus Bacteriophage Proteins, Katherine Dyer May 2020

Identification Of Genome-Linked Bacillus Bacteriophage Proteins, Katherine Dyer

Honors Program Theses

Small viruses that can infect bacteria, called bacteriophages, can be found in the soil. These viruses are being examined as a potential treatment against bacterial infections when antibiotics are not available or non-effective. Before viruses can be used as a medical treatment, they must be studied extensively. Previous attempts to sequence the terminal end of the genome of a bacteriophage QCM-11 (Quartz-Crystal-Microbalance-11: Q11) resulted in error. It is thought that a covalently bound protein may be attached to Q11’s DNA, blocking sequencing of the genome from the 5’ end. Proteins bound to the DNA of phages is not unheard of, …