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Full-Text Articles in Virology
Significance Of Viral Activity For Regulating Heterotrophic Prokaryote Community Dynamics Along A Meridional Gradient Of Stratification In The Northeast Atlantic Ocean, Kristina D.A. Mojica, Corina P.D. Brussaard
Significance Of Viral Activity For Regulating Heterotrophic Prokaryote Community Dynamics Along A Meridional Gradient Of Stratification In The Northeast Atlantic Ocean, Kristina D.A. Mojica, Corina P.D. Brussaard
Faculty Publications
How microbial populations interact influences the availability and flux of organic carbon in the ocean. Understanding how these interactions vary over broad spatial scales is therefore a fundamental aim of microbial oceanography. In this study, we assessed variations in the abundances, production, virus and grazing induced mortality of heterotrophic prokaryotes during summer along a meridional gradient in stratification in the North Atlantic Ocean. Heterotrophic prokaryote abundance and activity varied with phytoplankton biomass, while the relative distribution of prokaryotic subpopulations (ratio of high nucleic acid fluorescent (HNA) and low nucleic acid fluorescent (LNA) cells) was significantly correlated to phytoplankton mortality mode …
Development Of An Attenuated Zika Virus By Editing The 5’ Untranslated Region, E. Ashley Thompson
Development Of An Attenuated Zika Virus By Editing The 5’ Untranslated Region, E. Ashley Thompson
Master's Theses
Zika Virus (ZIKV) is a mosquito-transmitted flavivirus that usually causes no symptoms to mild febrile in humans, and it has been regarded as an insignificant pathogen to public health. However, recent outbreaks of ZIKV infection have revealed that ZIKV can cause severe neurological effects in adults, such as Guillain-Barre Syndrome (GBS), and in infants whose mothers acquired the virus during pregnancy, causing Congenital Zika Syndrome (CZS). Currently, no approved vaccine is available and there is a critical need to develop an effective and safe vaccine. While most vaccine developmental strategies target the viral prM-E protein of ZIKV, we aimed to …