Kinesiology Commons^™

Remote Ischemic Preconditioning Does Not Improve The Six Minutes Walk Test Performance In Chronic Heart Failure Patients: A Randomised Pilot Trial, Sarah-Maude Martin, Francois Lalonde, Elise Legault, Paula Ribeiro, Alain Steve Comtois, François Tournoux

International Journal of Exercise Science

International Journal of Exercise Science 14(2): 1354-1362, 2021. Cycles of ischemia and reperfusion induced with a pressure cuff on a skeletal muscle, also know as remote ischemic preconditioning (RIPC), appears to improve performance in different time-trial events in healthy individuals. Our primary goal was to assess the effect of RIPC in heart failure (HF) patients’ functional capacity using the six-minute walk test (6MWT). A randomized crossover design comparing RIPC (4 x five-minutes of upper arm ischemia) to the SHAM procedure was done in 15 patients prior to a 6MWT. The primary outcome measure was the total distance walked in a …

Genomics And Transcriptomics Landscapes Associated To Changes In Insulin Sensitivity In Response To Endurance Exercise Training, Louise Y. Takeshita, Peter K. Davidsen, John M. Herbert, Philipp Antczak, Matthijs K.C. Hesslink, Patrick Schrauwen, S. John Weisnagel, Jeremy M. Robbins, Robert E. Gerszten, Sujoy Ghosh, Mark A. Sarzynski Ph.D., Faha, Facsm, Claude Bouchard, Francesco Falciani

Faculty Publications

Despite good adherence to supervised endurance exercise training (EET), some individuals experience no or little improvement in peripheral insulin sensitivity. The genetic and molecular mechanisms underlying this phenomenon are currently not understood. By investigating genome-wide variants associated with baseline and exercise-induced changes (∆) in insulin sensitivity index (S_i) in healthy volunteers, we have identified novel candidate genes whose mouse knockouts phenotypes were consistent with a causative effect on S_i. An integrative analysis of functional genomic and transcriptomic profiles suggests genetic variants have an aggregate effect on baseline S_i and ∆S_i, focused around cholinergic …

The Interdependent Roles Of The Psychosocial Predictors Of Human Papillomavirus Vaccination Among Christian Parents Of Unvaccinated Adolescents, Ayokunle Olagoke, Rachel Caskey, Brenikki Floyd, Jennifer Herbert-Beirne, Andrew D. Boyd, Yamilé Molina

Health and Kinesiology Faculty Publications

Despite the availability of the human papillomavirus (HPV) vaccine, uptake has been sub-optimal among certain religious groups. Psychosocial factors (threat appraisal, coping appraisal, and attitudes) have been identified as independent determinants of HPV vaccination. However, their interdependent effects have not been tested. We examined the interdependency of these psychosocial factors in predicting HPV vaccination intention among Christian parents of unvaccinated adolescents (using a theory-driven conceptual model). A cross-sectional study of 342 participants showed that perceived self-efficacy (β = 0.2, 0.11–0.29, p = <0.0001) and perceived response efficacy of HPV vaccine (β = 0.65, 0.53–0.77. p < .0001) were positively associated with vaccination intention. Our mediation analysis (using the Preachers and Hayes’ approach) shows that attitudes toward HPV vaccination mediated 59% of the relationship between perceived self-efficacy to vaccinate child and HPV …

Adrenocortical Attunement, Reactivity, And Potential Genetic Correlates Among Parent-Daughter Dyads From Low-Income Families, Jennifer Byrd-Craven, Michael M. Criss, Jessica L. Calvi, Lixian Cui, Amanda Baraldi, Amanda Sheffield Morris

Athletic Performance Research

Examining the multitude of influences on the development of adolescent stress responses, especially among low-income families, is a critical and understudied topic in the field. The current study examined cortisol attunement between adolescent girls and parents (mostly mothers) from predominantly low-income, single parent, ethnic minority families before and after an in-laboratory disagreement discussion task. The sample consisted of 118 adolescents (M_age = 13.79 years, 76.3% ethnic minorities, 23.7% European Americans) and primary caregivers (M_age = 40.62 years; Mdn yearly income = $24,000; 43.2% single parents; 50% living below poverty line). We investigated oxytocin receptor (OXTR rs53576) …

Effects Of Varying Warmup Stimuli On Running Economy, Connor Bigenho

Electronic Theses and Dissertations

Purpose: The purpose of this study was to determine the effects of two potentiating warm-up stimuli (weighted-vest strides and plyometrics) on running economy (RE) over short (5-10 minutes) and longer durations (30+ minutes) of exercise in trained distance runners. Methods: Five recreationally trained male runners were recruited to participate in this study. Each trial consisted of a 10-min self-paced warm-up on the treadmill followed by baseline RE test and baseline leg-stiffness. This was immediately followed by one of two intervention warmup protocols. The protocols consisted of either a series of plyometric movements, 6 x 10-sec strides with a …

How Sweet It Is: Fellowship And Continuity In A Church-Based Fall Prevention Program With African American Elders In The Northeastern United States, Michelle L. Ramirez, Cedric H. Jones Jr., Carol Maritz, Donna Jensen

Humboldt Journal of Social Relations

Deaths from unintentional injuries are the seventh leading cause of death among older adults and falls account for the largest percentage of these deaths, with individuals aged ≥85 particularly vulnerable. Physical activity can reduce frailty and prevent falls; however, many elders are not physically active and women, ethnic minorities, and those with low education levels are the least active. Moreover, experiences of racial discrimination can lead to increased stress and unhealthy adaptive behaviors, and the cumulative effects of age and race related stressors have been shown to negatively impact the physical and mental health of elderly African Americans. Thus, participation …

International Society Of Sports Nutrition Position Stand: Caffeine And Exercise Performance, Nanci S. Guest, Trisha A. Vandusseldorp, Michael T. Nelson, Jozo Grgic, Brad J. Schoenfeld, Nathaniel D.M. Jenkins, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Jose Antonio, Jeffrey R. Stout, Eric T. Trexler, Abbie E. Smith-Ryan, Erica R. Goldstein, Douglas S. Kalman, Bill I. Campbell

Faculty Publications

Following critical evaluation of the available literature to date, The International Society of Sports Nutrition (ISSN) position regarding caffeine intake is as follows:1.Supplementation with caffeine has been shown to acutely enhance various aspects of exercise performance in many but not all studies. Small to moderate benefits of caffeine use include, but are not limited to: muscular endurance, movement velocity and muscular strength, sprinting, jumping, and throwing performance, as well as a wide range of aerobic and anaerobic sport-specific actions.2.Aerobic endurance appears to be the form of exercise with the most consistent moderate-to-large benefits from caffeine use, although the magnitude of …

An Acute Naproxen Dose Does Not Affect Core Temperature Or Interleukin-6 During Cycling In A Hot Environment, Dawn M. Emerson, Stephen Cl Chen, Toni M. Torres-Mcgehee, Craig E. Pfeifer, Charles C. Emerson, J Mark Davis

Faculty Publications

Non-steroidal anti-inflammatory drugs' anti-pyretic and anti-inflammatory effects has led some individuals to theorize these medications may blunt core body temperature (Tc) increases during exercise. We utilized a double-blind, randomized, and counterbalanced cross-over design to examine the effects of a 24-h naproxen dose (3-220 mg naproxen pills) and placebo (0 mg naproxen) on Tc and plasma interleukin-6 (IL-6) concentrations during cycling in a hot or ambient environment. Participants ( = 11; 6 male, 5 female; age = 27.8 ± 6.5 years, weight = 79.1 ± 17.9 kg, height = 177 ± 9.5 cm) completed 4 conditions: 1) placebo and ambient (Control); …

An Investigation Of Upper Extremity Motor Impairments In Children Diagnosed With Autism Spectrum Disorder: Motor Planning Vs Motor Execution, Patrick Anthony Cereceres

Open Access Theses & Dissertations

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder typically diagnosedwhen a child displays social and communication impairments, repetitive behaviors, and rhythmic movements like hand flapping. This disorder is unique because of the high variability of symptoms displayed between each individual who is diagnosed. Because of this, no neurological or physiological test exists to diagnose a child with ASD. Current diagnostic tests are various forms of interviews or observations which an experienced clinician must administer. While these tests have been instrumental in diagnosing children with ASD, many go undiagnosed, which can be detrimental as they transition into adulthood. Current literature indicates …

Cigarette Smoking After Aerobic Exercise: The Unfavorable Impacts On Vascular Function, Elizabeth J. Pekas, Song-Young Park

Health and Kinesiology Faculty Publications

It is well-accepted that vascular dysfunction plays a key role in the pathophysiology of cardiovascular diseases. Although vascular dysfunction is multi-faceted, exercise is a commonly recommended prophylactic strategy to preserve vascular function. We and others have shown that exercise training can elicit beneficial effects on vascular function (e.g., blood pressure and conduit artery function) in healthy and clinical populations^1-4. In fact, indices of vascular function are enhanced shortly after acute exercise^5,6, suggesting that the postexercise recovery period may be a crucial component for facilitating long-term vascular adaptations⁷. Poor habits may be …

The Impact Of Muscular Strength On Cardiovascular Disease Risk Factors, Joel Ernest Harden

Human Movement Studies & Special Education Theses & Dissertations

The purpose of this study was to determine the associations between isokinetic leg muscular strength and cardiovascular disease (CVD) risk factor characterizations in Americans aged 50 and older. Using a publicly available dataset from the National Health and Nutrition Examination Survey (NHANES), a secondary analysis was conducted on participants (males ≥50 yrs; females ≥55 yrs; N=10,858) pooled from 1999 to 2002. CVD risk factors were determined using the American College of Sports Medicine (ACSM) cutoff values, with all nine ACSM risk factors analyzed. CVD risk factor characterization was determined by creating CVD risk factor profiles (i.e., the total number of …

Absorption Kinetics Of Berberine And Dihydroberberine And Their Impact On Glycemia: A Randomized, Controlled, Crossover Pilot Trial, Jessica M. Moon, Kayla M. Ratliff, Anthony M. Hagele, Richard A. Stecker, Petey W. Mumford, Chad M. Kerksick

Faculty Scholarship

Berberine is a natural alkaloid used to improve glycemia but displays poor bioavailability and increased rates of gastrointestinal distress at higher doses. Recently, dihydroberberine has been developed to combat these challenges. This study was designed to determine the rate and extent to which berberine appeared in human plasma after oral ingestion of a 500 mg dose of berberine (B500) or 100 mg and 200 mg doses of dihydroberberine (D100 and D200). In a randomized, double-blind, crossover fashion, five males (26 ± 2.6 years; 184.2 ± 11.6 cm; 91.8 ± 10.1 kg; 17.1 ± 3.5% fat) completed a four-dose supplementation protocol …

Mental Fatigue On Landing Performance, Madison Marie Gaffney

Dissertations and Theses

Mental fatigue has been shown to impair physical performance, especially for endurance-based sports. However, little research has been done regarding the impacts of mental fatigue on shorter maximal effort movements during a common sport related activity such as the depth jump. The purpose of this study was to investigate the effects of mental fatigue on short maximal performance efforts and predisposing biomechanical variables for non-contact ACL tears during depth-jumps in 18 Division I female soccer players. Each participant completed five depth jumps, followed by a 30-minute Stroop task to induce mental fatigue, and then completed five more depth jumps. Multiple …

Physiological And Mechanical Comparisons Between Clipless And Flat Pedals, Katelyn Conroy

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to investigate the physiological and mechanical comparisons between clipless and flat pedals. Participants (n=4) completed two at-home 20-minute FTP tests: using clipless and flat pedals using Zwift. The order of conditions were randomized for each participant. Participants used their personal Smart Trainers, clipless pedals, and cycling shoes while flat pedals were provided (Syun-LP, Road Bike Platform Pedals). Power, heart rate and cadence were recorded and used for analysis. All dependent variables were compared using paired t-tests. Power was significantly greater for clipless (226.7 ± 46.2 W) vs. flat (215.2 ± 41.8 W) pedals (p …

Role Of Sex Differences On Cancer Cachexia Progression And Fibrosis During Cancer Cachexia Development, Wesley Haynie

Graduate Theses and Dissertations

Cancer cachexia is a multifactorial wasting syndrome characterized by losses in bodymass >5% and occurs in approximately 80% of all cancer patients. Chronic inflammation and fibrosis play roles in cancer cachexia and a greater understanding of these contributing pathways to this pathology will pave the way for potential therapeutic avenues. While inflammation and fibrosis have been researched in various models of cancer cachexia, little to no studies have been performed in both sexes as most previous studies focus on males. PURPOSE The purpose of these studies is to investigate the role of fibrosis on cancer cachexia development as well as …

Exercise Training Attenuates Ovariectomy-Induced Alterations In Skeletal Muscle Remodeling, Apoptotic Signaling, And Atrophy Signaling In Rat Skeletal Muscle, Eun-Jeong Cho, Youngju Choi, Jiyeon Kim, Jun Hyun Bae, Jinkyung Cho, Dong-Ho Park, Ju-Hee Kang, Jin Hwan Yoon, Eunmi Park, Dae Yun Seo, Sukho Lee, Hyo-Bum Kwak

Kinesiology Faculty Publications (Archived)

Purpose

Methods

Results

Early Impact Of The Covid-19 Pandemic On Promotion Of Infant Activity, Strength And Communication: A Qualitative Exploration, Kailey Snyder, Priyanka Chaudhary, Angela Pereira, Kimberly Masuda, Jessica Niski, Danae Dinkel

Journal Articles

Introduction

Fostering physical activity, muscle strengthening and communication skills in diverse environments are vital to ensuring healthy infant development; however, promotion of these skills may be impacted by the COVID-19 pandemic. Therefore, the purpose of this study was to explore healthcare workers, parents and childcare providers' perceptions of the pandemic's influence on how they engage with infants to promote physical activity, muscle strength and communication.

Methods

37 subjects (12 = parents; 12 = childcare providers, 13 = healthcare workers) participated in a semi-structured interview. Data were analyzed via an inductive content analysis.

Results

The majority of caregivers identified concerns related …

Examination Of Athlete Triad Symptoms Among Endurance-Trained Male Athletes: A Field Study, Erin M. Moore, Clemens Drenowatz, David F. Stodden, Kelly Pritchett, Thaddus C. Brodrick, Brittany T. Williams, Justin M. Goins, Toni M. Torres-Mcgehee

All Faculty Scholarship for the College of Education and Professional Studies

Background: Studies examining the physiological consequences associated with deficits in energy availability (EA) for male athletes are sparse.

Purpose: To examine male athlete triad components; low energy availability (LEA) with or without an eating disorder risk (ED), reproductive hormone [testosterone (T)], and bone mineral density (BMD) in endurance-trained male athletes during different training periods.

Methods: A cross-sectional design with 14 participants (age: 26.4 ± 4.2 years; weight: 70.6 ± 6.4 kg; height: 179.5 ± 4.3 cm; BMI: 21.9 ± 1.8 kg/m2) were recruited from the local community. Two separate training weeks [low (LV) and high (HV) training volumes] were used …

Examination Of Athlete Triad Symptoms Among Endurance-Trained Male Athletes: A Field Study, Erin M. Moore, Clemens Drenowatz, David F. Stodden, Kelly Pritchett, Thaddus C. Brodick, Brittany T. Williams, Justin M. Goins, Toni Torres-Mcgehee Phd, Lat, Atc

Faculty Publications

Background: Studies examining the physiological consequences associated with deficits in energy availability (EA) for male athletes are sparse.

Purpose: To examine male athlete triad components; low energy availability (LEA) with or without an eating disorder risk (ED), reproductive hormone [testosterone (T)], and bone mineral density (BMD) in endurance-trained male athletes during different training periods.

Methods: A cross-sectional design with 14 participants (age: 26.4 ± 4.2 years; weight: 70.6 ± 6.4 kg; height: 179.5 ± 4.3 cm; BMI: 21.9 ± 1.8 kg/m2) were recruited from the local community. Two separate training weeks [low (LV) and high (HV) training volumes] were used …

Access To Care, Reporting Behaviors, And Quality Of Athletic Training Service Interactions For Reserve Officers' Training Corps Cadets, Mary Catherine Avey, Amy F. Hand, Nancy A. Uriegas, Allison B. Smith, Zachary K. Winkelmann

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: Reserve Officers’ Training Corps (ROTC) programs prepare student-civilians to become leaders through strenuous physical and leadership training. Unlike their student-athlete counterparts who have direct access to athletic training services, ROTC cadets may or may not have a healthcare provider available. The purpose of this study was to examine the access to care and reporting behaviors of ROTC cadets with a secondary aim exploring the quality of healthcare service interactions relative to patient-centered care.

Methods: An online survey assessed access to care using a self-report tool on the type of medical providers available to the ROTC cadets (n=132, age=20±3 …

A Comparison Of Treatment Options For Carpal Boss: A Critically Appraised Topic, Megan M. Collins, Matthew J. Rivera

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Context: Carpal bossing is a bony growth or mass that typically occurs at the 2^nd or 3^rd carpometacarpal joint. Carpal bossing is often overlooked placing the patient at an increased risk for pain or injury, such as osteoarthritis or inflammatory joint disease if left untreated. Individuals such as combat sport athletes who experience repetitive trauma to this area are at a high risk to develop carpal bossing. The literature suggests conservative or surgical interventions to manage symptoms. The goal of this systematic review is to synthesize the current literature for clinical knowledge and intervention outcomes for carpal bossing. …

Utilizing Low-Intensity Blood Flow Restriction Training To Improve Aerobic Capacity In Physically Active And Injured Individuals: A Critically Appraised Topic, Melissa O. Miller, Kacee L. Hill, Jaclyn Arduini, Aric J. Warren

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: To determine if, in physically active individuals, low-intensity Blood Flow Restriction (BFR) training is more effective than training without BFR at improving measures of aerobic capacity.

Methods: A database search was conducted for articles that matched inclusion criteria (minimum level 2 evidence, physically active participants, comparison of low-intensity BFR to no BFR training, comparison of pre-post testing with aerobic fitness or performance, training protocols >2 weeks, studies published after 2010) by two authors and assessed by one using the PEDro scale (a minimum of 5/10 was required) to ensure level 2 quality studies that were then analyzed.

Results: Four …

Concussion-Related Alterations In Neural Activity During Emotion Recognition: Case Studies Of Short-Term And Residual Effects, Joshua Ricker, Kylee Smith, Alexandra Schmidt, Andrea Cripps, Palguna Thalla, Howard C. Cromwell, Xin Wang

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Concussions have recently become an area of concern among the general public, but a clear understanding of their total consequence is still being developed. Symptoms of concussions are wide-ranging, encapsulating a plethora of cognitive and emotional abilities that could be affected. Concussions transiently disrupt neural activation as well as behavioral responses across multiple categories. Skills pertaining to various aspects of emotions are often affected yet have rarely been studied after concussions. We present two case studies of collegiate athletes with a history of multiple concussions. This paper highlights the case of a collegiate athlete who had obtained two previous concussions …

Mindfulness Training's Effect Of Pain Outcomes In Musculoskeletal Pain: A Systematic Review, Elizabeth Cruze, Kenneth E. Games

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: Athletic trainers frequently address and treat musculoskeletal pain (MSK). Complementary and alternative techniques for treating pain are becoming more widely accepted and utilized in clinical practice. Mindfulness based stress reduction (MBSR) is a meditation-based program that is designed to help patients learn to feel things in a non-judgmental way. Previous systematic reviews on mindfulness training have focused a range of conditions including IBS, fibromyalgia, and migraines. The purpose of this systematic review was to examine if the literature supports the use of MBSR as an intervention for MSK pain. Methods: We completed a systematic review utilizing PRISMA guidelines. Inclusion …

Physiological, Musculoskeletal & Anthropometric Characteristics & Performance Between Competitive & Recreational Surfers: A Scoping Review, Harrison Stone, Lucy Douglas, James Furness, Kevin Kemp-Smith, Mike Climstein, Sean Newcomer

International Journal of Exercise Science

International Journal of Exercise Science 14(6): 1277-1293, 2021. Surfing is the ability to ride a surfboard along the unbroken section, wall or face of a wave, as it moves closer towards the shore. The purpose of this review is to provide an overview of the physiological, musculoskeletal and anthropometric characteristics that can differentiate between paddling and wave riding performance in competitive and recreational surfing populations. The eligibility criteria for this scoping review included articles that distinguished between multiple surfing ability groups, identified physiological, musculoskeletal or anthropometric characteristics, were peer reviewed, and directly related to the sport of surfing. The databases …

Impact Of Social Support On The Physical Activity Behaviors Of International College Students In The United States, Mohammed A. Alshehri, Aaron Kruse-Diehr, Justin Tyler Mcdaniel, Julie Partridge, Dawn Christina Null

International Journal of Exercise Science

International Journal of Exercise Science 14(5): 1305-1319, 2021. Research has suggested that international students’ transition to the United States is often correlated with less physical activity after arriving in the U.S). One reason might be related to reduced social support when living in a foreign environment. The purpose of this cross-sectional study was to assess the impact of social support on international college students’ physical activity behaviors. Participants (N = 318) from five public universities in one Midwest state completed an electronic survey assessing self-reported physical activity behaviors and perceived social support for exercise (SSE). Data analyses included multiple …

Tactical Circuit Training Improves Blood Pressure And Vascular Health More Than Resistance Training, Kelly C. Mclaughlin, Avery N. Perez, Stephanie Donahue, Deborah L. Feairheller

International Journal of Exercise Science

International Journal of Exercise Science 14(3): 1320-1333, 2021. Exercise training is known to reduce CVD risk factors; however, in tactical populations, like veterans and firefighters, the effects of different forms of exercise such as tactical circuit training (CT) or conventional resistance training (RT) is unclear. Thus, the purpose of this study was to compare changes in various CVD risk measures after 4-week tactical CT or RT programs. Thirty-seven firefighters (20 CT, 17 RT), 35% of whom were veterans, participated. Pre- and post-intervention measures included body fat (BF%), carotid artery intima media thickness (IMT), central and brachial BP, and indices of …

Exercise Variability Did Not Affect Muscle Thickness And Peak Force For Elbow Flexors After A Resistance Training Session In Recreationally-Trained Subjects, Ethan Smith, Andre Sepulveda, Vincent G.F. Martinez, Ashley Samaniego, Priscyla N. Marchetti, Paulo H. Marchetti

International Journal of Exercise Science

International Journal of Exercise Science 14(3): 1294-1304, 2021. The purpose of this study is to measure the acute effects of exercise variability on muscle thickness and physical performance after two resistance training (RT) protocols using the same or different exercises in recreationally-trained subjects. Fifteen resistance-trained men (23.1 ± 2.6 years, 83.4 ± 16.6 kg, 173.5 ± 8.3cm) performed one of two RT protocols: SINGLE: six sets of 10RM/two-minutes rest of the unilateral biceps curl exercise using cables or MIX: six sets of 10RM/two-minutes rest for the unilateral biceps curl exercises (cable: three sets and dumbbells: three sets, randomly). Muscle thickness …

Isometric Exercise Training: A Review Of Hypothesized Mechanisms And Protocol Application In Persons With Hypertension, Jacquelyn Rickson, Stephen A. Maris, Samuel A.E. Headley

International Journal of Exercise Science

International Journal of Exercise Science 14(2): 1261-1276, 2021. According to the American Heart Association 116.4 million, or 46% of US adults are estimated to have hypertension. Although, traditional moderate intensity aerobic exercise training is associated with reducing blood pressure by 5-8 mmHg, barriers to this modality of exercise training exist. Thus, the purpose of this review is to evaluate the mechanisms and incorporation of isometric exercise training (IET) as an adjunctive mode of exercise in a population with HTN. Based upon the articles reviewed from the years 2000-2020 which incorporated IET and provided clear protocols lasting 4 or more weeks, …

Claudicating Patients With Peripheral Artery Disease Have Meaningful Improvement In Walking Speed After Supervised Exercise Therapy, Hafizur Rahman, Iraklis Pipinos, Jason M. Johanning, George P. Casale, Mark A. Williams, Jonathan R. Thompson, Yohanis O'Neill-Casto, Sara A. Myers

Journal Articles

Objective

Supervised exercise therapy (SET) is a first-line treatment for patients with peripheral artery disease (PAD). The efficacy of SET is most commonly expressed by significant statistical improvement of parameters that do not clarify how each individual patient will benefit from SET. This study examined the minimal clinically important difference (MCID) in walking speed in claudicating patients with PAD after SET.

Methods

A total of 63 patients with PAD-related claudication (Fontaine stage II PAD) participated in a 6-month SET program. Self-selected walking speed was measured before and after SET. Distribution and anchor-based approaches were used to estimate the MCID for …