Kinesiology Commons^™

To Walk Or To Run – A Question Of Movement Attractor Stability, Peter C. Raffalt, Jenny A. Kent, Shane R. Wurdeman, Nicholas Stergiou

Journal Articles

During locomotion, humans change gait mode between walking and running as locomotion speed is either increased or decreased. Dynamical systems theory predicts that the self-organization of coordinated motor behaviors dictates the transition from one distinct stable attractor behavior to another distinct attractor behavior (e.g. walk to run or vice versa) as the speed is changed. To evaluate this prediction, the present study investigated the attractor stability of walking and running across a range of speeds evoking both self-selected gait mode and non-self-selected gait mode. Eleven subjects completed treadmill walking for 3 min at 0.89, 1.12, 1.34, 1.56, 1.79, 2.01, 2.24 …

Dynamic Interactive Artificial Intelligence: Sketches For A Future Ai Based On Human-Machine Interaction, Dobromir Dotov, Tom Froese

Journal Articles

We propose to designate as dynamic interactive artificial intelligence (dAI) a cross-section of existing work in artificially designed and artificially evolved systems meant for minimal forms of interaction with human users. This approach borrows principles from artificial life and human movement science to avoid pitfalls of traditional AI. Counter to tradition, it prioritizes user-machine inter-dependence over autonomy. It starts small and relies on incremental growth instead of trying to implement advanced complete functionality. It assumes a perceptual ontology founded on movement coordination rather than object classification. Its development process is better described as reverse self-organization rather than reverse engineering. dAI …

Assessing The Temporal Organization Of Walking Variability: A Systematic Review And Consensus Guidelines On Detrended Fluctuation Analysis, Deepak K. Ravi, Vivien Marmelat, William R. Taylor, Karl M. Newell, Nicholas Stergiou, Navrag B. Singh

Journal Articles

Human physiological signals are inherently rhythmic and have a hallmark feature in that even distant intrasignal measurements are related to each other. This relationship is termed long-range correlation and has been recognized as an indicator of the optimal state of the observed physiological systems, among which the locomotor system. Loss of long-range correlations has been found as a result of aging as well as disease, which can be evaluated with detrended fluctuation analysis (DFA). Recently, DFA and the scaling exponent α have been employed for understanding the degeneration of temporal regulation of human walking biorhythms in, for example, Parkinson disease …

Postural Control Is Altered In Females With Excessive Medial Knee Displacement, Joao R. Vaz, Nikolaos Stergiou, Ana Diniz, Ricardo Dinis, Pedro Pezarat-Correia

Journal Articles

Knee valgus motion observed during landing tasks has been proposed as a predictor of future knee injury. It mainly involves excess motion in the frontal plane and is known to be greater in individuals with excessive medial knee displacement (MKD). This affects postural control during sports manoeuvres. Previous sports medicine-related research suggests that the nature of these fluctuations provide rich and more sensitive information to identify risk of (re)injury. We aimed to investigate the fluctuations of the centre of pressure (CoP) in individuals with and without excessive MKD. Twenty females (12 controls; 8 excessive MKD) were instructed to perform single-leg …

Habitual Combined Exercise Protects Against Age-Associated Decline In Vascular Function And Lipid Profiles In Elderly Postmenopausal Women, Elizabeth J. Pekas, Won-Mok Son, Ronald Headid Iii, Song-Young Park, John Shin

Health and Kinesiology Faculty Publications

Postmenopausal status is associated with increased risks for cardiovascular diseases (CVD). This study investigated differences in vascular function, lipids, body composition, and physical fitness in elderly postmenopausal women active in combined resistance and aerobic exercise (CRAE) training for 1 year versus a sedentary cohort of similar-in-age counterparts. Elderly postmenopausal women performing habitual CRAE training for 1 year (age ~75 year; CRAE, n = 57) and elderly sedentary postmenopausal women (age ~78 year; SED, n = 44) were recruited. Arterial stiffness (brachial-to-ankle pulse-wave velocity, baPWV), blood pressure, blood lipids, anthropometrics, 2-min walking distance, and muscular strength were assessed for both groups. …

Filtering Affects The Calculation Of The Largest Lyapunov Exponent, Peter C. Raffalt, Ben Senderling, Nicholas Stergiou

Journal Articles

The calculation of the largest Lyapunov exponent (LyE) requires the reconstruction of the time series in an N-dimensional state space. For this, the time delay (Tau) and embedding dimension (EmD) are estimated using the Average Mutual Information and False Nearest Neighbor algorithms. However, the estimation of these variables (LyE, Tau, EmD) could be compromised by prior filtering of the time series evaluated. Therefore, we investigated the effect of filtering kinematic marker data on the calculation of Tau, EmD and LyE using several different computational codes. Kinematic marker data were recorded from 37 subjects during treadmill walking and filtered using a …

Exposure To Coronavirus News On Mainstream Media: The Role Of Risk Perceptions And Depression, Ayokunle Olagoke, Olakanmi Olagoke, Ashley M. Hughes

Health and Kinesiology Faculty Publications

Objective

The mainstream media tend to rely on news content that will increase risk perceptions of pandemic outbreaks to stimulate public response and persuade people to comply with preventive behaviours. The objective of this study was to examine associations between exposure to coronavirus disease (COVID-19) news, risk perceptions, and depressive symptoms.

Methods

Cross-sectional data were collected from 501 participants who were ≥18 years. Exposure to COVID-19 news was assessed as our exposure variable. We screened for depression (outcome variable) with the Patient Health Questionnaire and examined the roles of risk perceptions. Multiple linear regressions and mediation analysis with 1000 bootstrap …

The Effects Of Mat Pilates Training On Vascular Function And Body Fatness In Obese Young Women With Elevated Blood Pressure, Alexei Wong, Arturo Figueroa, Stephen M. Fischer, Reza Bagheri, Song-Young Park

Health and Kinesiology Faculty Publications

BACKGROUND

Effective nonpharmacological interventions targeting the enhancement of vascular function and decline of body fatness (BF) in obese individuals are indispensable for the prevention of hypertension and cardiovascular events in young adults. Mat Pilates training (MPT) has gained significant popularity worldwide, yet its effects on vascular function and body composition are understudied. We examined the effects of MPT on vascular function and BF in young obese women with elevated blood pressure (BP). METHODS

Twenty-eight young obese women with elevated BP were randomized to an MPT (n = 14) or a nonexercising control (CON, n = 14) group for 12 …

The Impact Of Aspirin Intake On Lactate Dehydrogenase, Arterial Stiffness, And Oxidative Stress During High-Intensity Exercise: A Pilot Study, Sang-Ho Lee, Elizabeth J. Pekas, Seungyong Lee, Ronald Headid Iii, Song-Young Park

Health and Kinesiology Faculty Publications

Aspirin is a common nonsteroidal anti-inflammatory drug used to reduce fever, pain, and inflammation. However, aspirin's anti-inflammatory properties may also prevent increased levels of blood lactate dehydrogenase, vascular arterial stiffness and oxidative stress induced by high-intensity exercise. The purpose of this study was to investigate the effects of 4 weeks of aspirin supplementation on lactate dehydrogenase activity, lactate, arterial stiffness, and antioxidant capacity during high-intensity exercise in Taekwondo athletes. Participants were randomly divided into two groups: aspirin supplementation (n = 10) and placebo-control (n = 10). Blood levels of lactate dehydrogenase (LDH) enzyme activity and lactate were assessed to examine …

Effects Of Footedness And Stance Asymmetry Confirm An Inter-Leg Metastable Coordination Dynamics Of Standing Posture, Steven J. Harrison, Jeffrey M. Kinsella-Shaw, Dobromir Dotov

Journal Articles

We investigated the patterns of coordination between the left and right legs that support the task of maintaining an upright standing posture. We used cross-wavelet analyses to assess coordination between the centers of pressure under the left and right feet. We recruited participants with a lateralized functional preference for their right leg, and we manipulated whether these participants stood with symmetric/asymmetric stances and whether their eyes were open or closed. Our hypotheses were derived from the Haken-Kelso-Bunz (HKB) model of interlimb coordination dynamics. Consistent with HKB model predictions, we observed (1) coordination taking the form of metastable, transient epochs of …

Vasodilatory And Vascular Mitochondrial Respiratory Function With Advancing Age: Evidence Of A Free Radically Mediated Link In The Human Vasculature, Soung Hun Park, Oh-Sung Kwon, Song-Young Park, Joshua C. Weavil, Jay R. Hydren, Van Reese, Robert H. I. Andtbacka, John R. Hyngstrom, Russell S. Richardson

Health and Kinesiology Faculty Publications

Recognizing the age-related decline in skeletal muscle feed artery (SMFA) vasodilatory function, this study examined the link between vasodilatory and mitochondrial respiratory function in the human vasculature. Twenty-four SMFAs were harvested from young (35 ± 6 yr, n = 9) and old (71 ± 9 yr, n = 15) subjects. Vasodilation in SMFAs was assessed, by pressure myography, in response to flow-induced shear stress, acetylcholine (ACh), and sodium nitroprusside (SNP) while mitochondrial respiration was measured, by respirometry, in permeabilized SMFAs. Endothelium-dependent vasodilation was significantly attenuated in the old, induced by both flow (young: 92 ± 3, old: 45 ± 4%) …

Effects Of Heated Water-Based Versus Land-Based Exercise Training On Vascular Function In Individuals With Peripheral Artery Disease, Song-Young Park, Alexei Wong, Won-Mok Son, Elizabeth J. Pekas

Health and Kinesiology Faculty Publications

Peripheral artery disease (PAD) is an atherosclerotic disease that is associated with poor vascular function, walking impairment, and reduced quality of life. Land-based exercise therapy (LBET) is frequently recommended to improve walking and reduce symptoms. Recently, evidence has suggested that heated-water exercise therapy (HWET) is an effective intervention for PAD. However, the efficacy of LBET versus HWET in PAD patients had not been elucidated. Therefore, we sought to compare effects of LBET with HWET on cardiovascular function, exercise tolerance, physical function, and body composition in PAD patients. PAD patients (n = 53) were recruited and randomly assigned to a …

Mmp9 Mediates Acute Hyperglycemia-Induced Human Cardiac Stem Cell Death By Upregulating Apoptosis And Pyroptosis In Vitro, Santosh K. Yadav, Tyler N. Kambis, Sumit Kar, Song-Young Park, Paras K. Mishra

Health and Kinesiology Faculty Publications

Providing a conducive microenvironment is critical to increase survival of transplanted stem cells in regenerative therapy. Hyperglycemia promotes stem cell death impairing cardiac regeneration in the diabetic heart. Understanding the molecular mechanisms of high glucose-induced stem cell death is important for improving cardiac regeneration in diabetic patients. Matrix metalloproteinase-9 (MMP9), a collagenase, is upregulated in the diabetic heart, and ablation of MMP9 decreases infarct size in the non-diabetic myocardial infarction heart. In the present study, we aim to investigate whether MMP9 is a mediator of hyperglycemia-induced cell death in human cardiac stem cells (hCSCs) in vitro. We created MMP9−/− hCSCs …

Lessons Learned: How To Organize Your Laboratory Meetings, Nicholas Stergiou

Journal Articles

In this issue, JAB continues a series of editorials from highlyimpactful faculty and researchers on“lessons learned”through-out their careers or lives. The hope is that the rest of us can benefitfrom their experiences. I would like to thank these individuals forsharing their thoughts with us.—Michael Madigan, Editor-in-ChiefNicholas Stergiou([email protected])is with the Divisionof Biomechanics and Research Development, University of Ne-braska Omaha, Omaha, NE; and the College of Public Health,University of Nebraska Medical Center, Omaha, NE.

Aromatic L-Amino Acid Decarboxylase Gene Therapy Enhanceslevodopa Response In Parkinson’S Disease, John G. Nutt, Carolin Curtze, Amie Hiller, Shannon Anderson, Paul S. Larson, Amber D. Van Laar, R. Mark Richardson, Marin E. Thompson, Alexander Sedkov, Mika Leinonen, Bernard Ravina, Krystof Bankiewicz, Chadwick W. Christine

Journal Articles

Background: As Parkinson’s disease progresses, levodopa treatment loses efficacy, partly through the loss of the endogenous dopamine-synthesizing enzyme L-amino acid decarboxylase (AADC). In the phase I PD-1101 study, putaminal administration of VY-AADC01, an investigational adeno-associated virus serotype-2 vector for delivery of the AADC gene in patients with advanced Parkinson’s disease, was well tolerated, improved motor function, and reduced antiparkinsonian medication requirements.

Objectives: This substudy aimed to determine whether the timing and magnitude of motor response to intravenous levodopa changed in PD-1101 patients after VY-AADC01administration.

Methods: Participants received 2-hour threshold (0.6 mg/kg/h) and suprathreshold (1.2 mg/kg/h) levodopa infusions …

How Stair Negotiation Affects Knee Joint Contact Forces In Individuals Post-Total Knee Arthroplasty, Todd Leutzinger

UNO Student Research and Creative Activity Fair

This study investigates how walking up and down stairs affects knee joint contact forces in individuals post-total knee arthroplasty compared to overground level walking and healthy controls.

Developing And Testing Of Low-Cost 3d Printed Prostheses To Restore And Improve Function Of Children With Congenital Or Traumatic Amputations, Rahul Raj, Christopher Copeland, Claudia Cortes Reyes, Kaitlin Fraser, David Salazar

UNO Student Research and Creative Activity Fair

The purpose of this investigation was to provide technical considerations and clinical evidence of the possible benefits and obstacles in the use of upper-limb 3D printed prostheses in paediatric populations. This information is crucial for clinicians interested in exploring the use of 3D printed prostheses for their patients. In the present study, children with congenital digit reductions (n=5); absent digits (one traumatic and four congenital) (n=5) and with upper-limb reductions (n=9). The perceived functionality of upper-limbs before the use of the prosthesis and after 4 months of use. In addition, gross dexterity, anthropometric measurements, active range of motion, and strength …

Determining The Optimal Tension For An Ankle-Foot Assistive Device, Cody Anderson

UNO Student Research and Creative Activity Fair

Introduction

Peripheral artery disease (PAD) is caused by atherosclerosis, a buildup of cholesterol and fatty acid deposits, which blocks blood flow to the arms, legs, and feet. Ankle assistive devices have recently been implemented in various clinical population to improve walking ability. Our group has developed an ankle assistive device to improve walking ability in patients with PAD. This study tested our newly developed assistive device with several tension assistance levels and their effect on metabolic cost.

Methodology

Ten healthy subjects were recruited for this study. A spring was attached to the posterior side of the device parallel to the …

The Effect Of Sensory Input On The Temporal Structure Of Center Of Pressure In Stroke Survivors, Samantha Chong

UNO Student Research and Creative Activity Fair

Stroke is the leading cause of disability that affects 17 million people worldwide. Patients post-stroke suffer from maintaining balance because the brain may not be able to receive or process visual, vestibular and proprioceptive sensory information: all of which contribute towards maintaining stability. Information provided by vision is important for spatial orientation, as it develops an environmental perspective. Proprioception is detected through the stretching of tendons and surrounding tissue and is able to help the brain determine spatial location. The vestibular system provides a sense of balance detecting rotations and linear accelerations through the vestibulo-ocular reflex. The vestibular system is …

Step Width Variability As A Discriminator Of Age-Related Gait Changes, Andreas Skiadopoulos, Emily E. Moore, Harlan Sayles, Kendra K. Schmid, Nicholas Stergiou

Journal Articles

Background

There is scientific evidence that older adults aged 65 and over walk with increased step width variability which has been associated with risk of falling. However, there are presently no threshold levels that define the optimal reference range of step width variability. Thus, the purpose of our study was to estimate the optimal reference range for identifying older adults with normative and excessive step width variability.

Methods

We searched systematically the BMC, Cochrane Library, EBSCO, Frontiers, IEEE, PubMed, Scopus, SpringerLink, Web of Science, Wiley, and PROQUEST databases until September 2018, and included the studies that measured step width variability …

Provider Reported Implementation Of Nutrition-Related Practices In Childcare Centers And Family Childcare Homes In Rural And Urban Nebraska, Dipti A. Dev, Aileen S. Garcia, David A. Dzewaltowski, Susan Sisson, Lisa Franzen-Castle, Zainab Rida, Natalie A. Williams, Carly Hillburn, Danae Dinkel, Deepa Srivastava, Christina Burger, Emily Hulse, Donnia Behrends, Natasha Frost

Health and Kinesiology Faculty Publications

Approximately 15 million children under age 6 are in childcare settings, offering childcare providers an opportunity to influence children’s dietary intake. Childcare settings vary in organizational structure – childcare centers (CCCs) vs. family childcare homes (FCCHs) – and in geographical location – urban vs. rural. Research on the nutrition-related best practices across these childcare settings is scarce. The objective of this study is to compare nutrition-related best practices of CCCs and FCCHs that participate in the Child and Adult Care Food Program (CACFP) in rural and urban Nebraska. Nebraska providers (urban n = 591; rural n = 579) reported implementation …

Reply, Matthew A. Fuglestad, Hernan Hernandez Md, Yue Gao, Henamari Ybay, Molly Schieber, Katyarina E. Brunette, Sara A. Myers, George P. Casale, Iraklis Pipinos

Journal Articles

Letter to the editor response

Auditory And Visual External Cues Have Different Effects On Spatial But Similar Effects On Temporal Measures Of Gait Variability, Joao R. Vaz, Troy Rand, Jessica Fujan-Hansen, Mukul Mukherjee, Nicholas Stergiou

Journal Articles

Walking synchronized to external cues is a common practice in clinical settings. Several research studies showed that this popular gait rehabilitation tool alters gait variability. There is also recent evidence which suggests that alterations in the temporal structure of the external cues could restore gait variability at healthy levels. It is unknown, however, if such alterations produce similar effects if the cueing modalities used are different; visual or auditory. The modality could affect gait variability differentially, since there is evidence that auditory cues mostly act in the temporal domain of gait, while visual cues act in the spatial domain of …

Swaying To The Complex Motion Of A Visual Target Affects Postural Sway Variability, Haralampos Sotirakis, Dimitrios A. Patikas, Nicholas Stergiou, Vassilia Hatzitaki

Journal Articles

Background

Voluntary shifting body weight in the anteroposterior direction is an important element of daily life activities, such as rising from a chair or initiating a step. In order to accommodate the daily-life challenges of such tasks, voluntary postural sway needs to be flexible and variable.

Research question

In this study we asked how whole-body tracking of a complex visual target motion with the concurrent provision of feedback modulates the variability of voluntary sway.

Methods

Twenty young adults (age: 27.10 ± 9.15years, height: 170.73 ± 9.40 cm, mass: 62.84 ± 11.48 kg) performed 132 cycles of voluntary antero-posterior sway, on …

Acl Injury And Reconstruction Affect Control Of Ground Reaction Forces Produced During A Novel Task That Simulates Cutting Movements, Amelia Lanier, Brian Knarr, Nicholas Stergiou, Lynn Snyder-Mackler, Thomas S. Buchanan

Journal Articles

After anterior cruciate ligament (ACL) injury and reconstruction, biomechanical and neuromuscular control deficits persist and 25% of those who have experienced an ACL injury will experience a second ACL rupture in the first year after returning to sports. There remains a need for improved rehabilitation and the ability to detect an individual's risk of secondary ACL rupture. Nonlinear analysis metrics, such as the largest Lyapunov exponent (LyE) can provide new biomechanical insight in this population by identifying how movement patterns evolve over time. The purpose of this study was to determine how ACL injury, ACL reconstruction (ACLR), and participation in …

University Of Nebraska At Omaha Department Of Biomechanics Annual Report 2019-2020, Department Of Biomechanics, University Of Nebraska At Omaha

Biomechanics Annual Report

This report contains:

A letter from the Director: Dr. Nick Stergiou

Articles on research that impacts the community

Article about the Movcentr Impact

Articles on Expanding horizons

Article on the people of UNO Biomechanics

Student Centered articles

Articles on Community Engagement

and Fun.

Modular Footwear That Partially Offsets Downhill Or Uphill Grades Minimizes The Metabolic Cost Of Human Walking, Prokopios Antonellis, Cory M. Frederick, Arash Mohammadzadeh Gonabadi, Philippe Malcolm

Journal Articles

Walking on different grades becomes challenging on energetic and muscular levels compared to level walking. While it is not possible to eliminate the cost of raising or lowering the centre of mass (COM), it could be possible to minimize the cost of distal joints with shoes that offset downhill or uphill grades. We investigated the effects of shoe outsole geometry in 10 participants walking at 1 m s−1 on downhill, level and uphill grades. Level shoes minimized metabolic rate during level walking (Psecond-order effect < 0.001). However, shoes that entirely offset the (overall) treadmill grade did not minimize the metabolic rate of walking on grades: shoes with a +3° (upward) inclination minimized metabolic rate during downhill walking on a −6° grade, and shoes with a −3° (downward) inclination minimized metabolic rate during uphill walking on a +6° grade (P interaction effect = 0.023). Shoe inclination influenced (distal) ankle joint parameters, including soleus muscle activity, ankle moment and work rate, whereas treadmill grade influenced (whole-body) ground reaction force and COM work rate as well as (distal) ankle joint parameters including tibialis anterior and plantarflexor muscle activity, ankle moment and work rate. Similar modular footwear could be used to minimize joint loads or assist with walking on rolling terrain.

Linear And Nonlinear Measures Of Postural Control In A Toddler With Cerebral Palsy: Brief Report, Samuel R. Pierce, Athylia C. Paremski, Julie Skorup, Nicholas Stergiou, Ben Senderling, Laura A. Prosser

Journal Articles

Purpose:

The purpose of this study was to describe changes in linear and nonlinear measures of postural control along with motor outcomes in a young child with cerebral palsy.

Summary of Key Points:

Posturography in sitting and standing, the Gross Motor Function Measure-66 (GMFM-66), and the Early Clinical Assessment of Balance (ECAB) were performed prior to, during, and after physical therapy. The child demonstrated independent sitting throughout the study and developed independent standing during the study. He made improvements in the GMFM-66 and ECAB throughout the study. Higher average values were found in all linear and nonlinear measures in standing …

Changes In Human Walking Dynamics Induced By Uneven Terrain Are Reduced With Ongoing Exposure, But A Higher Variability Persists, Jenny A. Kent, Joel H. Sommerfeld, Nicholas Stergiou

Journal Articles

During walking, uneven terrain alters the action of the ground reaction force from stride to stride. The extent to which such environmental inconsistencies are withstood may be revealed by the regulation of whole-body angular momentum (L) during walking. L quantifies the balance of momenta of the body segments (thigh, trunk, etc.) about their combined center of mass, and remains close to zero during level walking. A failure to constrain L has been linked to falls. The aim of this study was to explore the ability of young adults to orchestrate their movement on uneven terrain, illustrated by the …

Salt Restriction Lowers Blood Pressure At Rest And During Exercise Without Altering Peripheral Hemodynamics In Hypertensive Individuals, Stephen M. Ratchford, Ryan M. Broxterman, Taylor La Salle, Oh-Sung Kwon, Song-Young Park, Paul N. Hopkins, Russell S. Richardson, Joel D. Trinity

Health and Kinesiology Faculty Publications

Dietary salt restriction is a well-established approach to lower blood pressure and reduce cardiovascular disease risk in hypertensive individuals. However, little is currently known regarding the effects of salt restriction on central and peripheral hemodynamic responses to exercise in those with hypertension. Therefore, this study sought to determine the impact of salt restriction on the central and peripheral hemodynamic responses to static-intermittent handgrip (HG) and dynamic single-leg knee extension (KE) exercise in individuals with hypertension. Twenty-two subjects (14 men and 8 women, 51 ± 10 yr, 173 ± 11 cm, 99 ± 23 kg) forewent their antihypertensive medication use for …