Kinesiology Commons^™

Multi-Strain Probiotic Improves Subjective Sleep Quality With No Impact On Body Composition, Hemodynamics, And Physical Activity, Chad Kerksick, Jessca Moon, Kylie Walden, Anthony Hagele, L. E. Allen, Connor J. Gaige, Joesi M. Krieger, Ralf Jäger, Marco Pane, Petey Mumford

Faculty Scholarship

The objective of the study was to examine the impact of a multi-strain probiotic (MSP) on sleep, physical activity, and body composition changes. We used a randomised, double-blind, placebo-controlled approach with 70 healthy men and women (31.0 ± 9.5 years, 173.0 ± 10.4 cm, 73.9 ± 13.8 kg, 24.6 ± 3.5 kg/m2) supplemented daily with MSP (4 × 109 live cells Limosilactobacillus fermentum LF16, Lacticaseibacillus rhamnosus LR06, Lactiplantibacillus plantarum LP01, and Bifidobacterium longum 04; Probiotical S.p.A., Novara, Italy) or placebo (PLA). In response to supplementation (after 0, 2, 4, and 6 weeks of supplementation) and 3 weeks after stopping supplementation, …

Changes In Energy Expenditure, Dietary Intake, And Energy Availability Across An Entire Collegiate Women’S Basketball Season: Erratum, Breyannah R. Zanders, Brad S. Currier, Patrick Harty, Hannah A. Zabriskie, Charles R. Smith, Richard A. Stecker, Scott R. Richmond, Andrew R. Jagim, Chad Kerksick

Faculty Scholarship

Erratum

The Effects Of Protein And Carbohydrate Supplementation, With And Without Creatine, On Occupational Performance In Firefighters, Kaia Elstad, Conley Malone, Joel Luedke, Salvadore J. Jaime, Ward C. Dobbs, Thomas Almonroeder, Chad M. Kerksick, Adam Markert, Andrew R. Jagim

Faculty Scholarship

Background: The purpose of this study was to assess the effects of protein and carbohydrate supplementation, with and without creatine, on occupational performance in firefighters. Methods: Using a randomized, double-blind approach, thirty male firefighters (age: 34.4 ± 8.4 yrs., height: 1.82 ± 0.07 m; weight: 88.6 ± 12.5 kg; BF%: 17.2 ± 5.8%) were randomized to receive either (A.) 25 g of whey protein isolate + 25 g of carbohydrate powder (ProCarb group); or (B.) ProCarb + 5 g of creatine (Creatine group) in a double-blind fashion over a period of 21–26 days (depending on shift rotations) to evaluate …

Naturally Bicarbonated Water Supplementation Does Not Improve Anaerobic Cycling Performance Or Blood Gas Parameters In Active Men And Women, Anthony M. Hagele, Johnathan L. Boring, Jessica M. Moon, Kyle L. Sunderland, Petey W. Mumford, Chad M. Kerksick

Faculty Scholarship

The completion of high-intensity exercise results in robust perturbations to physiologic homeostasis, challenging the body’s natural buffering systems to mitigate the accumulation of metabolic by-products. Supplementation with bicarbonate has previously been used to offset metabolic acidosis, leading to improvements in anaerobic exercise performance. Purpose: The purpose of this study was to investigate the presence of ergogenic properties in naturally occurring low-dose bicarbonated water and their effects on anaerobic cycling performance and blood gas kinetics in recreationally active men and women. Methods: Thirty-nine healthy, recreationally active men and women (28.1 ± 8.0 years, 169.8 ± 11.7 cm, 68.9 ± 10.8 kg, …

Impact Of Probiotic Veillonella Atypica Fb0054 Supplementation On Anaerobic Capacity And Lactate, Kristen Gross, Marina Santiago, Joesi M. Krieger, Anthony M. Hagele, Kinga Zielinska, Jonathan Scheiman, Ralf Jäger, Alex Kostic, Chad Kerksick

Faculty Scholarship

Seven healthy, physically active men (n = 3) and women (n = 4) (30.7 ± 7.5 years, 172.7 ± 8.7 cm, 70.4 ± 11.6 kg, 23.6 ± 4.1 kg/m², 49.2 ± 8.4 mL/kg/min) supplemented for 14 days with a placebo (PLA) or 1 × 10¹⁰ CFU doses of the probiotic Veillonella atypica FB0054 (FitBiomics, New York, NY). Participants had safety panels, hemodynamics, lactate, and anaerobic capacity assessed. Stool samples were collected to evaluate for metagenomic and metabolomic changes. Exhaustion times were not different between groups, whereas anaerobic capacity tended to shorten with PLA (61.14 ± 72.04 s; 95% CI: −5.49, …

International Society Of Sports Nutrition Position Stand: Effects Of Essential Amino Acid Supplementation On Exercise And Performance, Arny A. Ferrnado, Robert R. Wolfe, Katie R. Hirsch, David D. Church, Shiloah A. Kviatkovsky, Michael D. Roberts, Jeffrey R. Stout, Drew E. Gonzalez, Ryan J. Sowinski, Richard B. Kreider, Chad Kerksick, Nicholas A. Burd, Stefan M. Pasiakos, Michael J. Ormsbee, Shawn M. Arent, Paul J. Arciero, Bill I. Campbell, Trisha A. Van Dusseldorp, Ralf Jager, Darryn S. Willoughby, Douglas S. Kalman, Jose Antonio

Faculty Scholarship

Position Statement: The International Society of Sports Nutrition (ISSN) presents this position based on a critical examination of literature surrounding the effects of essential amino acid (EAA) supplementation on skeletal muscle maintenance and performance. This position stand is intended to provide a scientific foundation to athletes, dietitians, trainers, and other practitioners as to the benefits of supplemental EAA in both healthy and resistant (aging/clinical) populations. EAAs are crucial components of protein intake in humans, as the body cannot synthesize them. The daily recommended intake (DRI) for protein was established to prevent deficiencies due to inadequate EAA consumption. The following conclusions …

Prevalence Of Adulteration In Dietary Supplements And Recommendations For Safe Supplement Practices In Sport, Andrew R. Jagim, Patrick Harty, Jacob L. Erickson, Grant M. Tinsley, Dan Garner, Andrew J. Galpin

Faculty Scholarship

The prevalence of dietary supplement use among athletes continues to rise with 60–80% of athletes often reporting current or previous use of dietary supplements. While select dietary ingredients have been shown to improve acute performance and enhance training adaptations over time, it is important to still consider the risk vs. reward for athletes before opting to consume a dietary supplement. Previous work has indicated that certain dietary supplements may pose risks for inadvertent doping, may be susceptible to mislabelling, could be banned by certain governing bodies of sport, or pose health risks for certain populations. The purpose of the current …

A Randomized Controlled Trial To Examine The Impact Of A Multi-Strain Probiotic On Self-Reported Indicators Of Depression, Anxiety, Mood, And Associated Biomarkers, Kylie E. Walden, Jessica M. Moon, Anthony M. Hagele, Leah E. Allen, Connor J. Gaige, Joesi M. Krieger, Ralf Jäger, Petey W. Mumford, Marco Pane, Chad M. Kerksick

Faculty Scholarship

Objective: To examine the efficacy of supplementing with a multi-strain probiotic (MSP) on changes associated with mood, anxiety, and neurotransmitter levels.

Method: In a randomized, double-blind, placebo-controlled fashion, 70 healthy men and women (31.0  ±  9.5  years, 173.0  ±  10.4  cm, 73.9  ±  13.8  kg, 24.6  ±  3.5  kg/m2 ) supplemented with a single capsule of MSP (a total daily dose of 4 × 109 colony forming units [CFU] comprised of a 1 × 109   CFU dose from each of the following strains: Limosilactobacillus fermentum LF16, Lacticaseibacillus rhamnosus LR06, Lactiplantibacillus plantarum LP01, and Bifidobacterium longum 04, Probiotical S.p.A., Novara, …

Sex Differences In Resting Metabolic Rate Among Athletes And Association With Body Composition Parameters: A Follow-Up Investigation, Andrew R. Jagim, Margaret T. Jones, Andrew T. Askow, Joel Luedke, Jacob L. Erickson, Jennifer B. Fields, Chad Kerksick

Faculty Scholarship

The purpose of this study was to examine sex differences in resting metabolic rate (RMR) and associations between measured RMR and body composition parameters in athletes. One-hundred and ninety collegiate men (n = 98; age: 20.1 ± 1.6 yr.; body mass: 92.7 ± 17.5 kg; height: 181.6 ± 6.2 cm, body mass index: 28.0 ± 4.7 kg/m2) and women (n = 92; age: 19.4 ± 1.1 yr.; body mass: 65.2 ± 11.0 kg; height: 168.0 ± 6.6 cm, body mass index: 23.0 ± 3.6 kg/m2) athletes volunteered to participate in this study. Athletes completed a body composition assessment using air …

Editorial: Pre-Workout Nutrition, Chad Kerksick, Jamie N. Pugh

Faculty Scholarship

Unavailable.

International Society Of Sports Nutrition Position Stand: Coffee And Sports Performance, Lonnie M. Lowery, Dawn E. Anderson, Kelsey F. Scanlon, Abigail Stack, Guillermo Escalante, Sara C. Campbell, Chad M. Kerksick, Michael T. Nelson, Tim N. Vandusseldorp, Douglas S. Kalman, Bill I. Campbell, Richard B. Kreider, Jose Antonio

Faculty Scholarship

Based on review and critical analysis of the literature regarding the contents and physiological effects of coffee related to physical and cognitive performance conducted by experts in the field and selected members of the International Society of Sports Nutrition (ISSN), the following conclusions represent the official Position of the Society:

(1) Coffee is a complex matrix of hundreds of compounds. These are consumed with broad variability based upon serving size, bean type (e.g. common Arabica vs. Robusta), and brew method (water temperature, roasting method, grind size, time, and equipment).

(2) Coffee’s constituents, including but not limited to caffeine, have neuromuscular, …

Effects Of Fucoidan Supplementation On Inflammatory And Immune Response After High-Intensity Exercise, Bridget A. Mcfadden, Caroline S. Vincenty, Alexa J. Chandler, Harry P. Cintineo, Blaine S. Lints, Gianna F. Mastrofini, Shawn M. Arent

Faculty Scholarship

Introduction: High-intensity exercise (HIE) can damage the musculotendon complex and impact the immune response, resulting in post-exercise inflammation. Sufficient rest and recovery will improve muscular resilience against future damaging bouts; however, HIE with minimal durations of rest is common in athletic competitions that facilitate persistent inflammation and immune dysregulation. Fucoidans are fucose-rich sulfated polysaccharides with demonstrated anti-inflammatory and pro-immune responses. Fucoidans may improve inflammation and immune responses, which may prove beneficial for individuals who regularly engage in repeated HIE. The research purpose was to investigate the safety and efficacy of fucoidans on inflammatory and immune markers following HIE.

Methods …

The Effects Of Calisthenic Exercises On The Strength And Aerobic Abilities Of Sedentary Adult Women, Kathleen Langley

Theses

The thesis, The Effects of Calisthenic Exercises on the Strength and Aerobic Abilities of Sedentary Adult Women, investigates the impact of structured calisthenic training on sedentary women aged 18–40. The study was conducted over four weeks and measured participants' strength, aerobic abilities, balance, and perceived wellness before and after the intervention. Calisthenics, a form of strength training using bodyweight exercises, became popular during the COVID-19 pandemic due to its accessibility and minimal equipment requirements.

Participants engaged in a program consisting of dynamic warm-ups, high-intensity interval training circuits, and cooldowns three times a week. Results showed significant improvements in upper …

Evaluation Of Novel Beverage Formulations For Hydration Enhancement In Humans, Grant M. Tinsley, Madelin R. Siedler, Christian Rodriguez, Patrick Harty, Matthew T. Stratton, Sarah J. White, Dale S. Keith, Jacob J. Green, Jake R. Boykin, Abegale D. Williams, Brielle Dehaven, Alexandra Brojanac, Ethan Tinoco

Faculty Scholarship

This study evaluated the influence of novel beverage formulations on bioimpedance- and urine-based hydration markers. Thirty young healthy adults (n=16 females, n=14 males; age: 23.2±3.7 years; BMI: 24.3±3.3 kg/m2 ) participated in a randomized, double-blind, placebo-controlled, crossover study. Participants completed three conditions with baseline bioimpedance, urine, and body mass assessments, followed by ingestion of one liter of a test beverage over a 30-minute period. The three beverages were: active hydration formulation in still (AFstill) or sparkling (AFspark) water and a still water control. The active formulations were identical in concentrations of alpha-cyclodextrin and complexing agents. Following beverage ingestion, bioimpedance assessments …

Physiological Measurements Pre/Post Ultra-Marathon Distance Race, Karolina Zavisiute, Scott Richmond, Chad Kerksick, Kyle Sunderland, Petey Mumford

2023 Student Academic Showcase

Endurance running events like 100 miles distance races are becoming more popular. Humans are eager to explore their limits by challenging themselves to run 100 miles distance races. However, there are many research gaps still exist to fully understand the impact on the body that 100 miles endurance event has.

The aim of this study was to measure and analyze the impact of the 100 miles endurance race among recreational runners. Ten male recreational runners (age 36.6 ± 14.1) were screened before and after completing 100 miles distance running event in Missouri. Test screening included VO2 max, RMR, BIA, Ultrasound …

Changes In Hamstring Muscle Thickness And Pennation Angle Following Nordic Exercise In A Post-Surgical Acl Patient: A Case Study, Aaliyah M. Moore, Petey W. Mumford

2023 Student Academic Showcase

This study aims to utilize ultrasound imaging to investigate the effects of Nordic hamstring exercise on a post-surgical ACL rugby patient who had a hamstring tear in the contralateral leg of his ACL tear. The study will also examine any changes in the patient's ACL leg hamstring compared to the torn hamstring leg. The patient's Biodex test results will also be incorporated to determine if there is a correlation between muscle thickness and pennation angle changes. Ultrasound scans were taken 2 months, 4 months and will be taken again at 6 months post-surgery, following biodex assessments. Ultrasound images have shown …

Female Swimmers Exhibit Greater Isometric Force Symmetry Across The Shoulder Girdle Than Male Swimmers, Lyssa Wood, Kyle Sunderland

2023 Student Academic Showcase

The Athletic Shoulder (ASH) test was developed to measure force across the shoulder girdle. This test can be used to assess symmetry and potential injury risk in upper-body sports. The purpose was to determine the differences in the supine-to-prone ratio of isometric shoulder force production between male and female swimmers. Forty-five Lindenwood swimmers (F=23, M=22) participated in this cross-sectional study. Athletes performed bilateral isometric shoulder contractions in both the supine and the prone laying position with arms straight and shoulders abducted 135˚ (“Y”). Female simmers had an higher average ratio (76.5%±13.5%) compared to males (68.1%±11.2%) independent of the arm tested. …

Peak Torque Ratios Of Hamstrings To Quadriceps Do Not Differ Between Positions Or Angular Velocities In Female Collegiate Rugby Athletes, Amanda Ware, Ava L. Denner, Kyle Sunderland

2023 Student Academic Showcase

The relative strength of hamstrings to quadriceps (H:Q) is an important measure for determining anterior cruciate ligament (ACL) injury risk, which is more prevalent in female athletes. The purpose was to examine H:Q at varying angular velocities in different position of female college rugby athletes. The dominant leg of forty-seven female college rugby athletes was evaluated via isokinetic dynamometry at 60 deg/s, 180 deg/s, 240 deg/s, and 300 deg/s. Concentric peak torques were utilized to determine H:Q. H:Q was not significantly different between positions. Additionally, there were no significant changes in H:Q at different angular velocities independent of position. These …

Hamstrings To Quadriceps Peak Torque Ratios Are Similar Between Positions In Male College Rugby Athletes, Ava Denner, Amanda Ware, Kyle Sunderland

2023 Student Academic Showcase

Decreased hamstrings strength relative to quadriceps strength (H:Q) is a potential risk factor for anterior cruciate ligament (ACL) injuries. The purpose was to determine the H:Q at varying angular velocities in male college rugby athletes. Thirty-eight male college rugby athletes volunteered for this study. Concentric peak torques were utilized to determine H:Q in the dominant leg with isokinetic dynamometry at 60 deg/s, 180 deg/s, 240 deg/s and 300 deg/s. There was no significant difference among position groups in peak torques, regardless of speed. H:Q was significantly lower at 60 deg/s compared to all other velocities. While H:Q does beneficially increase …

Arm Isometric Force Production In Ncaa Softball Players Is Greater In The Dominant Arm Independent Of Arm Angle, Nicole Henson, Kyle Sunderland

2023 Student Academic Showcase

Arm Isometric Force Production in NCAA Softball Players is Greater in the Dominant Arm Independent of Arm Angle

N. Henson1, M. Gersch1, K. Sunderland1

1Exercise and Performance Nutrition Laboratory, College of Science, Technology, and Health, Lindenwood University, St. Charles, MO, USA

The Athletic Shoulder (ASH) test is used to examine strength symmetry between dominant and non-dominant shoulders. Our purpose was to examine shoulder isometric force production in college softball players at two arm angles. Seventeen college softball players performed bilateral isometric shoulder contractions on dual force plates while laying prone with arms straight and shoulders at 135˚ (“Y”) and 180˚ …

Identifying Risk Of Acl Injury In Collegiate Male Rugby Players Across A Single Training Year, Caleb Small, Lauren Tighe

2023 Student Academic Showcase

The purpose of this study to examine collegiate male rugby players’ susceptibility for sustaining an ACL injury over the course of an entire season using the biodex strength assessment, standardized functional movement screen, and Y-balance test. Participants included five male collegiate rugby players who play in the back line ranging from age eighteen through twenty-three. Baseline testing was conducted during preseason training and re-assessed every four weeks throughout the entire season. Assessment measures remained the same throughout all testing trials, in addition to a subjective patient questionnaire. Following data collection, three out of the five participants showed deficiency of hamstring …

Assessment Of Muscular Anatomical And Physiological Development During Injury Rehabilitation, Nicholas Andrews, Petey Mumford, Lauren Tighe

2023 Student Academic Showcase

After an injury occurs, there are many physiological regressions that occur. These regressions lead to altered muscle thickness, muscle length, strength and power potentials, motor recruitment, and neuromuscular control. These variables are further exacerbated if the given injury requires surgical intervention. Rehabilitation aids in reducing these regressions and is important both pre-surgery and post-surgery when intervention beyond rehabilitation is needed. Ultrasound imaging can be utilized to monitor the progression of a muscle's specific muscles anatomy. The muscles of interest are dependent upon the injury, The purpose of this study is to monitor short-term muscular adaptations to establish their importance in …

A Cross-Sectional Examination Of Wrist Wrap Use Prevalence And Characterization For Ergogenic Purposes In Actively Competing Powerlifters, Dillon Harris, Thomas Cardaci, Harry Cintineo, Richard Pham, Kristen Dunsmore, Leslee Funderburk, Steven Machek

Faculty Scholarship

Purpose: Wrist wraps are regularly incorporated by competitive powerlifters, but several product-specific variations may influence any potential ergogenic benefits. In addition, the prevalence of athletic wrist wrap use is hitherto undescribed.

Methods: Seventy actively competing powerlifters (n=70; 27±6y) who competed in the last two years were randomly recruited at sanctioned meets, whereby wrist wrap use descriptive data (wrap style [F or S], wrap length, and events used), wrap tightness (assessed via pulse oximeter-detected oxygen saturation (SpO2) and subjective discomfort [Borg CR10+]), as well as post-meet bench press one repetition maximum (1RM) were collected. Wrist wrap use prevalence data (wrap …

Energy Expenditure And Availability In Active Individuals With Physical Disabilities, Scott Richmond, Amanda Bayer, Chad Kerksick, Heather Pennington, Petey Mumford, Annie Alameda

Faculty Scholarship

The purpose of this study was to evaluate the risk of low energy availability (LEA) in a population of active individuals with physical disabilities. Healthy, active males and females with a physical disability (n=13; Mean±SD; Age: 26.4±6.5 years; Height: 143.4±59.6 cm; Body mass: 57.5±27.3 kg; Fat-free mass: 41±20.8 kg;) were recruited to participate in this study. Participants were expected to track their exercise energy expenditure (EEE) and energy intake (EI) over the course of five days using portable wrist and chest-strap heart rate monitors. Body composition assessment completed via dual-energy x-ray absorptiometry (DXA) and resting energy expenditure (REE) performed via …

International Society Of Sports Nutrition Position Stand: Nutritional Concerns Of The Female Athlete, Stacy T. Sims, Chad M. Kerksick, Abbie E. Smith-Ryan, Xanne A.K. Janse De Jonge, Katie R. Hirsch, Shawn M. Arent, Susan Joyce Hewlings, Susan M. Kleiner, Erik Bustillo, Jaime L. Tartar, Valerie G. Starratt, Richard B. Kreider, Casey Greenwalt, Liliana I. Renteria, Michael J. Ormsbee, Trisha A. Vandusseldorp, Bill I. Campbell, Douglas S. Kalman, Jose Antonio

Faculty Scholarship

Based on a comprehensive review and critical analysis of the literature regarding the nutritional concerns of female athletes, conducted by experts in the field and selected members of the International Society of Sports Nutrition (ISSN), the following conclusions represent the official Position of the Society: 1. Female athletes have unique and unpredictable hormone profiles, which influence their physiology and nutritional needs across their lifespan. To understand how perturbations in these hormones affect the individual, we recommend that female athletes of reproductive age should track their hormonal status (natural, hormone driven) against training and recovery to determine their individual patterns and …

International Society Of Sports Nutrition Position Stand: Energy Drinks And Energy Shots, Andrew R. Jagim, Patrick S. Harty, Grant M. Tinsley, Chad M. Kerksick, Adam M. Gonzalez, Richard B. Kreider, Shawn M. Arent, Ralf Jager, Abbie E. Smith-Ryan, Jeffrey R. Stout, Bill I. Campbell, Trisha Vandusseldorp, Jose Antonio

Faculty Scholarship

Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on a critical analysis of the literature regarding the effects of energy drink (ED) or energy shot (ES) consumption on acute exercise performance, metabolism, and cognition, along with synergistic exercise-related performance outcomes and training adaptations. The following 13 points constitute the consensus of the Society and have been approved by the Research Committee of the Society: Energy drinks (ED) commonly contain caffeine, taurine, ginseng, guarana, carnitine, choline, B vitamins (vitamins B1, B2, B3, B5, B6, B9, and B12), vitamin C, vitamin A (beta carotene), vitamin D, …

Metabolic Impact Of Feeding Prior To A 60-Min Bout Of Moderate-Intensity Exercise In Females In A Fasted State, Kayla M. Ratliff, Chad M. Kerksick, Jessica M. Moon, Anthony M. Hagele, Johnathan L. Boring, Kylie Walden, Connor J. Gaige, Richard A. Stecker, Kyle L. Sunderland, Petey W. Mumford

Faculty Scholarship

Background: The metabolic impact of pre-exercise feeding of protein or carbohydrate on fat oxidation and energy expenditure rates, especially, in females, is poorly understood.

Methods: Recreationally active females (n = 15, 32 ± 10 years, 164.8 ± 5.6 cm, 63.5 ± 9.3 kg, 23.4 ± 3.2 kg/m2) completed four testing sessions in a randomized, double-blind, crossover fashion after fasting overnight. Participants ingested isovolumetric and isoenergetic solutions containing either 25 g of whey protein, casein protein, carbohydrate (CHO), or a non-caloric placebo (PLA). Participants then completed 60 min of treadmill exercise at 15% below ventilatory threshold 30 min after ingestion. …

Probiotic Bc30 Improves Amino Acid Absorption From Plant Protein Concentrate In Older Women, Kylie E. Walden, Anthony M. Hagele, Logan S. Orr, Kristen N. Gross, Joesi M. Krieger, Ralf Jäger, Chad M. Kerksick

Faculty Scholarship

Weizmannia coagulans GBI-30, 6086 (BC30) has previously been shown to increase protein digestion in an in vitro model of the stomach and small intestine and amino acid appearance in healthy men and women after ingestion of milk protein concentrate. The impact of ingesting BC30 with other protein sources or in other demographics is largely unknown. The purpose of this study was to examine the impact of adding BC30 to a 20-g dose of a blend of rice and pea protein on postprandial changes in blood amino acids concentrations in healthy, older women. Healthy, older females (n = 30, 58.5 …

Effects Of Creatine Monohydrate Timing On Resistance Training Adaptations And Body Composition After 8 Weeks In Male And Female Collegiate Athletes, Nicholas E. Dinan, Anthony Hagele, Andrew R. Jagim, Michael G. Miller, Chad M. Kerksick

Faculty Scholarship

Background: Limited research is available on the potential impact of creatine monohydrate administration before or after workouts among athletes. This study aimed to investigate the effects of pre- vs. post-exercise creatine monohydrate supplementation on resistance training adaptations and body composition.

Methods: In a randomized, double-blind, placebo-controlled, parallel design, 34 healthy resistance-trained male and female athletes were randomly assigned and matched according to fat free mass to consume a placebo, or 5-g dose of creatine monohydrate within 1 h before training, or within 1 h after training for 8 weeks, while completing a weekly resistance training program. Participants co-ingested 25-gram doses …

Lgd-4033 And Mk-677 Use Impacts Body Composition, Circulating Biomarkers, And Skeletal Muscle Androgenic Hormone And Receptor Content: A Case Report, Thomas D. Cardaci, Steven B. Machek, Dylan T. Wilburn, Jeffrey L. Heileson, Dillon R. Harris, Harry P. Cintineo, Darryn S. Willoughby

Faculty Scholarship

LGD-4033, a selective androgen receptor modulator, and MK-677, a growth hormone secretagogue, are becoming increasingly used amongst recreationally-active demographics. However, limited data exist describing their effects on health- and androgen-related biomarkers. The purpose of this case study is to report changes in body composition and biomarkers during and after continued co-administration of LGD-4033 and MK-677. We additionally aimed to examine muscular strength and intramuscular androgen-associated biomarkers relative to non-users. A 25-year-old male ingested LGD-4033 [10 mg] and MK-677 [15 mg] daily for 5 weeks. Blood and body composition metrics were obtained pre-, on-, and post-cycle. One repetition maximum (1RM) leg …