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Full-Text Articles in Other Immunology and Infectious Disease
Flattening The Curve: The Effects Of Intervention Strategies During Covid-19, Kelly A. Reagan, Rachel J. Pryor, Gonzalo M. Bearman, David M. Chan
Flattening The Curve: The Effects Of Intervention Strategies During Covid-19, Kelly A. Reagan, Rachel J. Pryor, Gonzalo M. Bearman, David M. Chan
Spora: A Journal of Biomathematics
COVID-19 has plagued countries worldwide due to its infectious nature. Social distancing and the use of personal protective equipment (PPE) are two main strategies employed to prevent its spread. A SIR model with a time-dependent transmission rate is implemented to examine the effect of social distancing and PPE use in hospitals. These strategies’ effect on the size and timing of the peak number of infectious individuals are examined as well as the total number of individuals infected by the epidemic. The effect on the epidemic of when social distancing is relaxed is also examined. Overall, social distancing was shown to …
Impulse Vaccination Model For The Control Of Devil Facial Tumor Disease, Zachary Bobbitt, Timothy Comar, Megan O. Powell, Catherine Roberts, Nicholas Schneider, Teagen Smith
Impulse Vaccination Model For The Control Of Devil Facial Tumor Disease, Zachary Bobbitt, Timothy Comar, Megan O. Powell, Catherine Roberts, Nicholas Schneider, Teagen Smith
Spora: A Journal of Biomathematics
Devil facial tumor disease (DFTD) is a cancer that affects Tasmanian devils and that has caused the devil population to grossly decline since 1996. We present an SEIVR model to explore if recent advances in DFTD vaccines can help the wild population recover. Considering both and bi-annual impulse of vaccinating wild devils through food drops and introducing vaccinated captive-bred devils into the population, we explore the vaccine efficacy, percent of healthy devils receiving the vaccine, and years of campaign necessary for the devil population to have a long-term recovery. Based on our initial parameter estimations, we find a stable population …
Age-Structured And Vaccination Models Of Devil Facial Tumor Disease, Christopher D. Bruno, Timothy Comar, Megan O. Powell, Adjo Tameklo
Age-Structured And Vaccination Models Of Devil Facial Tumor Disease, Christopher D. Bruno, Timothy Comar, Megan O. Powell, Adjo Tameklo
Spora: A Journal of Biomathematics
Tasmanian devil populations have been devastated by devil facial tumor disease (DFTD) since its first appearance in 1996. The average lifespan of a devil has decreased from six years to three years. We present an age-structured model to represent how the disease has affected the age and breeding structures of the population. We show that with the recent increase in the breeding of juvenile devils, the overall devil population will increase but not nearly to pre-DFTD levels. The basic reproductive number may be increased with the influx of young breeding devils. In addition, our model shows that the release of …