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Articles 1 - 3 of 3
Full-Text Articles in Other Immunology and Infectious Disease
Investigating Alternative Induction Of The S. Aureus 80a Prophage, Jody Caretti
Investigating Alternative Induction Of The S. Aureus 80a Prophage, Jody Caretti
Student Scholar Showcase
Widespread antibiotic resistance has quickly become one of the most concerning crises affecting modern medicine, especially in cases of Staphylococcal infections, which have become resistant to all ��-lactam antibiotics. As a result, research into alternative forms of treatment for bacterial infections is a top priority. Bacteriophage therapy is a popular candidate for replacing antibiotics, due to the way the viruses interact with the bacteria. The 80�� prophage integrates its DNA into Staphylococcus aureus strain 10616 via the lysogenic cycle, and replicates with the bacterial cell. When stressed, the bacteria stop replicating and the prophage stimulates the lytic cycle, activating transcription …
Do Paraben Derivatives Alter T Cell Immunity?, Hailey Kintz
Do Paraben Derivatives Alter T Cell Immunity?, Hailey Kintz
Spring Presentation of Undergraduate Research
T cells immunity is linked to a complex system of cytokines that determine differentiation of naïve T cells into Th1, Th2, Th17, and Treg cells. Estrogen production or periods of elevated production have been correlated with an anti-inflammatory state in which Th2 and Treg cells are up-regulated. Such responses in the immune system are capable of supporting pre-cancerous activity. We are investigating the tie between the xenoestrogen compounds found in cosmetics, parabens, and their ability to regulate T cell immunity. Testing parabens and paraben derivatives with weaker estrogen receptor association will allow for a better understanding of the interplay between …
Analysis Of The Chondroitinase Operon Of Flavobacterium Columnare, Erin L. Sorlien
Analysis Of The Chondroitinase Operon Of Flavobacterium Columnare, Erin L. Sorlien
Senior Honors Projects
Analysis of the chondroitinase operon of Flavobacterium columnare
Erin Sorlien
Major
Cell and Molecular Biology, Chemistry
Advisor
Dr. David R. Nelson
Date
May 2, 2013
Keywords
Flavobacterium columnare, columnaris disease, chondroitin AC lyase, complementation, csl operon
Abstract
Flavobacterium columnare, an opportunistic bacterial pathogen of fish, is the causative agent of columnaris disease (CD). The bacterium is a Gram-negative rod that exhibits gliding motility and avidly forms biofilms. CD affects both wild and cultured freshwater fish, and continues to cause large economic losses to the fish farming industry. According to an investigation conducted by the National Animal Health Monitoring System, CD …