Open Access. Powered by Scholars. Published by Universities.®

Immunopathology Commons™

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 6 of 6

Full-Text Articles in Immunopathology

Partial Immunity To Mycoplasma Gallisepticum After An Initial Infection Is Long-Lasting And Reduces Transmission In Flocks Of Canaries, Madeline Sudnick Aug 2024

Partial Immunity To Mycoplasma Gallisepticum After An Initial Infection Is Long-Lasting And Reduces Transmission In Flocks Of Canaries, Madeline Sudnick

Graduate Theses and Dissertations

Pathology during a second infection can be influenced by immunity and an increase in resistance or tolerance of individuals. Population-level differences in the ability to maintain immunity can lead to contrasting survival outcomes between groups and determine how future outbreaks will spread. However, long term wildlife disease surveillance can be challenging due to lack of infrastructure and host-pathogen specific tests. Calculating disease transmission likelihood requires understanding individual-level heterogeneity in pathology and behavior, and there is limited knowledge in understanding how populations in different stages of an epidemic will transmit disease. In Chapter I, we aim to help fill a gap …


Temporal, Phenotypic, And Quantitative Characterization Of Thyroid Infiltrating Mononuclear Cells During Development Of Spontaneous Autoimmune Thyroiditis In Obese Strain Chickens, Katelyn M. Clark May 2023

Temporal, Phenotypic, And Quantitative Characterization Of Thyroid Infiltrating Mononuclear Cells During Development Of Spontaneous Autoimmune Thyroiditis In Obese Strain Chickens, Katelyn M. Clark

Poultry Science Undergraduate Honors Theses

The Obese strain (OS) of chickens spontaneously develops autoimmune thyroiditis and is a well-established biomedical model for Hashimoto’s thyroiditis in humans. Both conditions are characterized by the infiltration of the thyroid glands with mononuclear cells resulting in destruction of the thyroid tissue and impairment of the thyroid’s endocrinological functions. Past studies have described mononuclear cell infiltration in thyroids of the OS chickens, but the time-course, cell composition, and relative amounts of the various mononuclear cells infiltrating the thyroids has not been well defined. In this project, the mononuclear cell infiltrate was characterized phenotypically and quantitatively in OS chickens over the …


Phenotypic Analysis And Localization Of Leukocytes At The Site Of Intradermal Injection Of Phytohemagglutinin In Chickens, Kallie Alyce Sullivan Dec 2016

Phenotypic Analysis And Localization Of Leukocytes At The Site Of Intradermal Injection Of Phytohemagglutinin In Chickens, Kallie Alyce Sullivan

Graduate Theses and Dissertations

Phytohemagglutinin (PHA) is commonly used to gain insight into an individual’s cellular immuno-competence. PHA is typically injected intradermally (i.d.) into the skin (e.g. wing web) and the tissue swelling response is then monitored, whereby the extent of the swelling positively relates to the individual’s cellular immune system capabilities. Although i.d. injected PHA was shown to stimulate mononuclear cell- and basophil-infiltration to the site of injection, reports on temporal, qualitative and quantitative aspects of the local PHA response are limited. The objective of this study was to use the growing feather (GF) as a cutaneous test-site to assess and monitor the …


Effects Of Purified Salmonella Enteritidis Endotoxin On The Immune Response Of Balb/C Mice, John B. Barnett, John W. Jutila Jan 1981

Effects Of Purified Salmonella Enteritidis Endotoxin On The Immune Response Of Balb/C Mice, John B. Barnett, John W. Jutila

Journal of the Arkansas Academy of Science

Wasting disease was produced in neonatal Balb/c mice with purified Salmonella enteritidis endotoxins. The endotoxins were chemically characterized to provide the study with a potent endotoxin with constant biological activity. Neonatal mice received an initial injection of 35 μg/g body weight of endotoxin and a dose of 75 μg every third day until day 18. The degree of wasting was estimated by the runting (weight loss) index. Mortality was calculated to be 46%, with a mean survival time of approximately 15 days. The hematologic studies conducted at days 10, 20, and 30 showed an absolute neutrophilia and leukocytosis by day …


Immune Responses Of Rats To Antigens Of Moloney Leukemia Virus, Erratum, Frances B. Soderberg, Susan G. Tai, Joe M. Jones Jan 1981

Immune Responses Of Rats To Antigens Of Moloney Leukemia Virus, Erratum, Frances B. Soderberg, Susan G. Tai, Joe M. Jones

Journal of the Arkansas Academy of Science

No abstract provided.


Immune Responses Of Rats To Antigens Of Moloney Leukemia Virus, Frances B. Soderberg, Susan G. Tai, Joe M. Jones Jan 1980

Immune Responses Of Rats To Antigens Of Moloney Leukemia Virus, Frances B. Soderberg, Susan G. Tai, Joe M. Jones

Journal of the Arkansas Academy of Science

No abstract provided.