Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Aestivation (1)
- Aranetoxin (1)
- Behavioral fever (1)
- Brain microbiome (1)
- CNS immune responses (1)
-
- Comparative Immunology (1)
- Ecoimmunology (1)
- Evolutionary Immunology (1)
- Gastropods (1)
- Gut-brain axis (1)
- Immunity (1)
- Invasiveness (1)
- Invertebrate Immunology (1)
- Life history (1)
- Lungfish (1)
- Mitogenome (1)
- Mollusca (1)
- Mucosal Immunity (1)
- Nasal (1)
- Neuroimmunology (1)
- Next-generation sequencing (1)
- Polyamines (1)
- Sensory neurons (1)
- Stress (1)
- Teleost (1)
Articles 1 - 5 of 5
Full-Text Articles in Immunity
Ecoimmunology Of Dirty Physella Acuta Snails, Kevin Arthur Mcquirk
Ecoimmunology Of Dirty Physella Acuta Snails, Kevin Arthur Mcquirk
Biology ETDs
Research on Physella acuta, an invasive freshwater snail, reveals insights into its parasitology, fitness, and molecular biology. Morphological and molecular analyses revealed two distinct mitogenomic lineages, local (B) and invasive (A) strains of native P. acuta, both having comparable trematode infection rates, suggesting that the low infection rates observed from A in invaded regions result from "enemy release" rather than immune incompatibility. Fitness assessments showed that while lineages A and B performed similarly under laboratory conditions, rewilding experiments revealed significantly higher fitness in lineage A. Transcriptomic profiling supported these differences, with A snails showing greater immune-related gene expression and …
Host-Microbiome Interactions In The Teleost Brain, Amir Mani Varnoosfaderani
Host-Microbiome Interactions In The Teleost Brain, Amir Mani Varnoosfaderani
Biology ETDs
This dissertation investigates host-microbial interactions within the teleost brain, previously considered sterile. Reviewing current literature highlights significant gaps in understanding teleost brain immunity, despite prevalent neurotropic diseases. We mapped the immune profiles of rainbow trout brains and meninges, revealing the olfactory bulbs as the immune effector part of the brain and the optic tectum as a nod2 expression hub. High il6 and il10 levels were noted in the telencephalon. A persistent bacterial community within healthy salmonid brains shares diversity with gut and blood microbiota. Brain bacterial isolates exhibit genomic signatures for brain colonization and polyamine biosynthesis. The microbiota shifts across …
Mucosal Immune System Of African Lungfish, Ryan D. Heimroth
Mucosal Immune System Of African Lungfish, Ryan D. Heimroth
Biology ETDs
Conquering land was an apex moment in the evolution of vertebrates. Physiologically, the first vertebrates to transition to life on land had to adapt in order to survive in an oxygen-rich environment where gravitational forces and limited water prevailed. Several extant vertebrates including anurans and lungfish, survive droughts by undergoing aestivation. Unfavorable environmental conditions trigger lungfish to aestivate. Aestivation is a process of metabolic torpor wherein the fish will encase itself in a mucus cocoon and not move until favorable environmental conditions (food and water) are reintroduced. Aestivation can be reproduced in laboratory settings and, thus, lungfish can be used …
Physella Acuta, Comparative Immunology And Evolutionary Aspects Of Gastropod Immune Function, Jonathan H. Schultz
Physella Acuta, Comparative Immunology And Evolutionary Aspects Of Gastropod Immune Function, Jonathan H. Schultz
Biology ETDs
Gastropod immunobiology has benefitted from investigations focused on the planorbid snail Biomphalaria glabrata, intermediate host for the human parasite Schistosoma mansoni. Though such concentrated efforts have elucidated fascinating aspects of invertebrate immunity, they have not provided full knowledge regarding the evolution of immune function among other gastropod species. This dissertation presents the importance of making strategic choices regarding which organisms to select for comparative immunology. Herein, the choice was made to investigate the immunobiology of Physella acuta, a freshwater snail species of the Physidae, a sister family to Planorbidae to which B. glabrata belongs. Benefiting greatly from …
From Olfaction To Immunity: Characterization Of Nasal Immunity In Bony Fish, Ali Sepahi
From Olfaction To Immunity: Characterization Of Nasal Immunity In Bony Fish, Ali Sepahi
Biology ETDs
The olfactory system is a common route pathogen entry in vertebrates. As a consequence, the nasopharynx-associated lymphoid tissue (NALT) needs to rapidly clear infections without compromising the sense of olfaction. NALT is present in teleost fish but its cellular and molecular mechanisms of action have not been investigated to this date. This dissertation focuses on three aims: 1. investigating the role of CCL19-like as a primordial chemokine in vertebrate nasal immunity, 2. determining the presence of tissue microenvironments within the olfactory organ (OO) of rainbow trout, and 3. understanding the immune contributions of olfactory sensory neurons (OSNs) in teleosts against …