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Immunology and Infectious Disease Commons™
Open Access. Powered by Scholars. Published by Universities.®
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- Physical Sciences and Mathematics (33)
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- Leishmania (3)
- Devil facial tumor disease (2)
- Potential Treatment (2)
- Tasmanian devil (2)
- Active subspaces (1)
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- Aedes aegypti (1)
- Anthrax (1)
- Antibody testing (1)
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- COVID-19 pandemic (1)
- Comparative analysis (1)
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- Continuous ODE model (1)
- Cytokines (1)
- DFTD (1)
- Data fitting (1)
- Dengue Transmission (1)
- Electric Field (1)
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Articles 1 - 30 of 52
Full-Text Articles in Immunology and Infectious Disease
A Probabilistic Modeling Analysis Of The Longitudinal Immune Response To Infection And Vaccination Across Demographic Groups And Pulmonary Symptoms, James O'Hanlon, Kaitlyn Sullivan, Lyndsey M. Muehling, Glenda Canderan, Jie Sun, Judith A. Woodfolk, Jeffrey M. Wilson, Rayanne A. Luke
A Probabilistic Modeling Analysis Of The Longitudinal Immune Response To Infection And Vaccination Across Demographic Groups And Pulmonary Symptoms, James O'Hanlon, Kaitlyn Sullivan, Lyndsey M. Muehling, Glenda Canderan, Jie Sun, Judith A. Woodfolk, Jeffrey M. Wilson, Rayanne A. Luke
Spora: A Journal of Biomathematics
Antibody and cytokine kinetics describe the dynamic response to immune events such as infection and vaccination. These dynamics are not fully understood, and mathematical characterization may help explain variability across demographic groups and pulmonary symptoms post-acute infection. We fit time-dependent probability models to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) data to obtain distributions of longitudinal antibody response and cytokine values. To assess differences between groups, an overlap metric is applied to the modeled response curves. Our antibody models suggest significant differences between male and female populations and demonstrate deficient antibody responses of less-healthy groups such as smokers. Our cytokine …
Decoding Early Covid-19 Responses Using Mathematical Modeling Of Social Distancing Strategies Across Multiple Countries, Sri Gunturu, Suki Lewis, Katelyn Nguyen, Asma Azizi
Decoding Early Covid-19 Responses Using Mathematical Modeling Of Social Distancing Strategies Across Multiple Countries, Sri Gunturu, Suki Lewis, Katelyn Nguyen, Asma Azizi
Spora: A Journal of Biomathematics
During the early phase of the COVID-19 pandemic, before vaccines were available, countries implemented diverse combinations of social-distancing (SD) measures shaped by cultural norms and public acceptance. These differences produced varied outcomes in controlling viral spread, offering lessons for future health-crisis preparedness. We performed a reverse-engineering analysis of early COVID-19 case data from five socioculturally distinct countries—India, Vietnam, Italy, Finland, and the United States—selected to capture a range of initial prevalence levels. Using mathematical modeling and data fitting, we inferred the relative contributions of three SD interventions: face masking, quarantine, and isolation of infected individuals. We then employed an efficiency …
[Kyda] The Role Of Human Movement On The Spread Of Mosquito-Borne Diseases, Omar Saucedo
[Kyda] The Role Of Human Movement On The Spread Of Mosquito-Borne Diseases, Omar Saucedo
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
[Kyda] Biologically Grounded Surrogate-Driven Parameter Inference For Sparsely Observed Dynamical Systems, Joshua C. Macdonald
[Kyda] Biologically Grounded Surrogate-Driven Parameter Inference For Sparsely Observed Dynamical Systems, Joshua C. Macdonald
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Immune Dysregulation In Covid-19: Mathematical Modeling Of The Within-Host Dynamics, Pagnapech Ngoun, Nicolas Alvarez, Ayesh Awad, Hwayeon Ryu
Immune Dysregulation In Covid-19: Mathematical Modeling Of The Within-Host Dynamics, Pagnapech Ngoun, Nicolas Alvarez, Ayesh Awad, Hwayeon Ryu
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Probabilistic Modeling Of Antibody Kinetics Post Infection And Vaccination, Rayanne Luke, Prajakta Bedekar, Anthony J. Kearsley
Probabilistic Modeling Of Antibody Kinetics Post Infection And Vaccination, Rayanne Luke, Prajakta Bedekar, Anthony J. Kearsley
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Representing Ewe-Lamb Contact Dynamics In An Agent-Based Model Of Enzootic Abortion Of Ewes, Kelly R. Buch, Cara J. Sulyok
Representing Ewe-Lamb Contact Dynamics In An Agent-Based Model Of Enzootic Abortion Of Ewes, Kelly R. Buch, Cara J. Sulyok
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling The Impact Of Treatment During An Ongoing Tuberculosis Outbreak, Bach Le, Jude Shive, Erin N. Bodine
Modeling The Impact Of Treatment During An Ongoing Tuberculosis Outbreak, Bach Le, Jude Shive, Erin N. Bodine
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Kreig: Examining Affinity Maturation And Antigenic Drift With An Agent-Based Model, Jasmine Af Kreig, Jannatul Ferdous, Ruian Ke, Ruy M. Ribeiro
Kreig: Examining Affinity Maturation And Antigenic Drift With An Agent-Based Model, Jasmine Af Kreig, Jannatul Ferdous, Ruian Ke, Ruy M. Ribeiro
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Saving The Devils Is In The Details, Megan O. Powell
Saving The Devils Is In The Details, Megan O. Powell
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Incorporating Adaptive Human Behavior Into Epidemiological Models Using Equation Learning, Austin Barton, Jordan Klein, Jonathan Greer, Kevin Flores, Patrick Haughey
Incorporating Adaptive Human Behavior Into Epidemiological Models Using Equation Learning, Austin Barton, Jordan Klein, Jonathan Greer, Kevin Flores, Patrick Haughey
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Msis-Ledder: Empowering Future Physicians: Modeling Disease Transmission With Netlogo To Encourage Mathematical Reasoning, Anne E. Yust
Msis-Ledder: Empowering Future Physicians: Modeling Disease Transmission With Netlogo To Encourage Mathematical Reasoning, Anne E. Yust
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Mathematical Model Of Acanthocephalan Parasite Infection In Gull-Billed Terns, Charlotte Moser
A Mathematical Model Of Acanthocephalan Parasite Infection In Gull-Billed Terns, Charlotte Moser
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Multicellular And Multiscale Models Of Microbes And Host Systems, Elebeoba May
Multicellular And Multiscale Models Of Microbes And Host Systems, Elebeoba May
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Dynamical System Model Of Dengue Transmission For Rio De Janeiro, Brazil, Gregory Schmidt, Benjamin Whipple, Vinodh Chellamuthu, Xiaoxia Xie
A Dynamical System Model Of Dengue Transmission For Rio De Janeiro, Brazil, Gregory Schmidt, Benjamin Whipple, Vinodh Chellamuthu, Xiaoxia Xie
Spora: A Journal of Biomathematics
The dengue virus is a serious concern in many parts of the world, including Brazil. As data indicates, a prominent vector for dengue is the mosquito Aedes aegypti. By using the dengue incidence records from the Brazilian SINAN database, we estimate the population of A. aegypti within the city of Rio de Janeiro. Using historical climate data for Rio de Janeiro and the computed population estimates, we extend an existing model for the population dynamics of mosquitoes to incorporate precipitation in aquatic stages of development for A. aegypti.
Modeling The Impact Of Hospitalization On The Death Rate Of An Ebola Outbreak, Erin N. Bodine, Jana V. Turner
Modeling The Impact Of Hospitalization On The Death Rate Of An Ebola Outbreak, Erin N. Bodine, Jana V. Turner
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
How Within-Host Priority Effects Between Specialist And Generalist Pathogens Affect Disease Risk, Jing Jiao, Michael H. Cortez
How Within-Host Priority Effects Between Specialist And Generalist Pathogens Affect Disease Risk, Jing Jiao, Michael H. Cortez
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Undergraduate Research In Mathematical Modeling, Glenn Ledder
Undergraduate Research In Mathematical Modeling, Glenn Ledder
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Poliomyelitis Virus Vs Smallpox: An Ordinary Differential Equation Model Comparison, Kate Mcgough
Poliomyelitis Virus Vs Smallpox: An Ordinary Differential Equation Model Comparison, Kate Mcgough
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Flattening The Curve: The Effects Of Intervention Strategies During Covid-19, Kelly A. Reagan, Rachel J. Pryor, Gonzalo M. Bearman, David M. Chan
Flattening The Curve: The Effects Of Intervention Strategies During Covid-19, Kelly A. Reagan, Rachel J. Pryor, Gonzalo M. Bearman, David M. Chan
Spora: A Journal of Biomathematics
COVID-19 has plagued countries worldwide due to its infectious nature. Social distancing and the use of personal protective equipment (PPE) are two main strategies employed to prevent its spread. A SIR model with a time-dependent transmission rate is implemented to examine the effect of social distancing and PPE use in hospitals. These strategies’ effect on the size and timing of the peak number of infectious individuals are examined as well as the total number of individuals infected by the epidemic. The effect on the epidemic of when social distancing is relaxed is also examined. Overall, social distancing was shown to …
Impulse Vaccination Model For The Control Of Devil Facial Tumor Disease, Zachary Bobbitt, Timothy Comar, Megan O. Powell, Catherine Roberts, Nicholas Schneider, Teagen Smith
Impulse Vaccination Model For The Control Of Devil Facial Tumor Disease, Zachary Bobbitt, Timothy Comar, Megan O. Powell, Catherine Roberts, Nicholas Schneider, Teagen Smith
Spora: A Journal of Biomathematics
Devil facial tumor disease (DFTD) is a cancer that affects Tasmanian devils and that has caused the devil population to grossly decline since 1996. We present an SEIVR model to explore if recent advances in DFTD vaccines can help the wild population recover. Considering both and bi-annual impulse of vaccinating wild devils through food drops and introducing vaccinated captive-bred devils into the population, we explore the vaccine efficacy, percent of healthy devils receiving the vaccine, and years of campaign necessary for the devil population to have a long-term recovery. Based on our initial parameter estimations, we find a stable population …
Long-Term Dynamics Of The Kidney Disease Epidemic Among Hiv-Infected Individuals, Heather Gudaz, Henry A. Ogu, Elissa J. Schwartz
Long-Term Dynamics Of The Kidney Disease Epidemic Among Hiv-Infected Individuals, Heather Gudaz, Henry A. Ogu, Elissa J. Schwartz
Spora: A Journal of Biomathematics
One of many risks facing HIV+ individuals is the development of kidney dysfunction and end stage kidney disease (ESKD). A differential equation-based mathematical model was developed to assess the impact of antiretroviral therapy on the progression to kidney disease and on reducing mortality due to kidney failure. Analytical and numerical predictions of long-term HIV+ ESKD prevalence show that therapy can lead to either extremely low levels of disease prevalence or increased prevalence, depending on drug efficacy levels and mechanisms of action. Maintenance of HIV+ ESKD prevalence below one individual is possible with sufficient efficacy (e.g., 99%) against the progression from …
Applying Immuno-Epidemiology Principles To Violence, Anna H. Sisk, Nina H. Fefferman, Judy Day, Patricia Bamwine
Applying Immuno-Epidemiology Principles To Violence, Anna H. Sisk, Nina H. Fefferman, Judy Day, Patricia Bamwine
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
The Effect Of Fcgammariia Polymorphisms On Dengue Outbreak Severity, Leah Darwin, Richard V. Clarke
The Effect Of Fcgammariia Polymorphisms On Dengue Outbreak Severity, Leah Darwin, Richard V. Clarke
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling And Preparedness: The Transmission Dynamics Of Covid-19 Outbreak In Provinces Of Ecuador, Carlos E. Bustamante Orellana, Jordy Cevallos-Chavez, Cesar Montalvo, Jeff Sulliavan, Edwin Michael, Anuj Mubayi
Modeling And Preparedness: The Transmission Dynamics Of Covid-19 Outbreak In Provinces Of Ecuador, Carlos E. Bustamante Orellana, Jordy Cevallos-Chavez, Cesar Montalvo, Jeff Sulliavan, Edwin Michael, Anuj Mubayi
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Mathematical Model Of The Effect Of Social Distancing On The Spread Of Covid-19, Anna Singley, Hannah Callender Highlander
A Mathematical Model Of The Effect Of Social Distancing On The Spread Of Covid-19, Anna Singley, Hannah Callender Highlander
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
In Silico Modelling For The Treatment Of Gastric Cancer, Leonardo F. Martinez, Diana Gamboa, Paul A. Valle
In Silico Modelling For The Treatment Of Gastric Cancer, Leonardo F. Martinez, Diana Gamboa, Paul A. Valle
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Mobility Impact In The Spreading Of Covid-19 In Ecuador, Jordy Cevallos-Chavez, Carlos E. Bustamante Orellana, Cesar Montalvo, Anuj Mubayi, Edwin Michael, Edwin Michael
Mobility Impact In The Spreading Of Covid-19 In Ecuador, Jordy Cevallos-Chavez, Carlos E. Bustamante Orellana, Cesar Montalvo, Anuj Mubayi, Edwin Michael, Edwin Michael
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Using Empirical And Theoretical Approaches To Control Outbreaks Of An Emerging Disease (Swimmer’S Itch) In The Midwest Of The U.S.A., Gregory J. Sandland, James Peirce
Using Empirical And Theoretical Approaches To Control Outbreaks Of An Emerging Disease (Swimmer’S Itch) In The Midwest Of The U.S.A., Gregory J. Sandland, James Peirce
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Combating Tuberculosis: Using Time-Dependent Sensitivity Analysis To Develop Strategies For Treatment And Prevention, Kendall B. Clark, Mayleen Cortez, Cristian Hernandez, Beth E. Thomas, Allison L. Lewis
Combating Tuberculosis: Using Time-Dependent Sensitivity Analysis To Develop Strategies For Treatment And Prevention, Kendall B. Clark, Mayleen Cortez, Cristian Hernandez, Beth E. Thomas, Allison L. Lewis
Spora: A Journal of Biomathematics
Although many organizations throughout the world have worked tirelessly to control tuberculosis (TB) epidemics, no country has yet been able to eradicate the disease completely. We present two compartmental models representing the spread of a TB epidemic through a population. The first is a general TB model; the second is an adaptation for regions in which HIV is prevalent, accounting for the effects of TB/HIV co-infection. Using active subspaces, we conduct time-dependent sensitivity analysis on both models to explore the significance of certain parameters with respect to the spread of TB. We use the results of this sensitivity analysis to …