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Immunology and Infectious Disease Commons™
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Articles 31 - 52 of 52
Full-Text Articles in Immunology and Infectious Disease
The Effect Of Demographic Variability, Environmental Variability, And Periodic Fluctuations On Stochastic Epidemic Models, Kaniz Fatema Nipa, Linda J. Allen
The Effect Of Demographic Variability, Environmental Variability, And Periodic Fluctuations On Stochastic Epidemic Models, Kaniz Fatema Nipa, Linda J. Allen
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Mathematical Model Of The Inflammatory Response To Pathogen Challenge, Lester Caudill, Fiona Lynch
A Mathematical Model Of The Inflammatory Response To Pathogen Challenge, Lester Caudill, Fiona Lynch
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling The Transmission Of Wolbachia In Mosquitoes For Controlling Mosquito-Borne Diseases, Zhuolin Qu
Modeling The Transmission Of Wolbachia In Mosquitoes For Controlling Mosquito-Borne Diseases, Zhuolin Qu
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Biomathematics And Social Justice: Reinventing Models Of Disease Spread To Study Efficacy Of Bystander Violence Prevention, Hannah Callender Highlander
Biomathematics And Social Justice: Reinventing Models Of Disease Spread To Study Efficacy Of Bystander Violence Prevention, Hannah Callender Highlander
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Simulating Antibiotic Resistance In The Computer Lab And Biology Lab: Ideas For Undergraduate Projects, Anne E. Yust
Simulating Antibiotic Resistance In The Computer Lab And Biology Lab: Ideas For Undergraduate Projects, Anne E. Yust
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Proposed Interventions For The Containment Of Influenza In Boarding Schools And Small Colleges, Alexis Vittengl
Proposed Interventions For The Containment Of Influenza In Boarding Schools And Small Colleges, Alexis Vittengl
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Parameter Sensitivity For In Vitro Anthrax Studies, Yareley Gonzalez, Maria Macias-Bedolla, Megan O. Powell
Parameter Sensitivity For In Vitro Anthrax Studies, Yareley Gonzalez, Maria Macias-Bedolla, Megan O. Powell
Spora: A Journal of Biomathematics
Studies done on interactions between spores and macrophages done in vitro show inconsistent results based on experimental protocol and inhibit meaningful extrapolation to in vivo. In this study, we perform a sensitivity analysis of a model representing in vitro studies of interactions between anthrax spores and macrophages to help address the effects of these inconsistencies. We perform both local and global analyses using Latin hypercube sampling and partial rank correlation coefficients. Our analysis indicates the amount of intracellular bacteria over time is most sensitive to the killing of intracellular bacteria by the macrophages and replication of the bacteria inside …
Out Of The Shell: Exploring The Phagocytic Capabilities Of The B Cell And Isolated Lymphoid Follicle-Lie Structures In The Red-Eared Slider, Trachemys Scripta, Marc A. Ashford Jr.
Out Of The Shell: Exploring The Phagocytic Capabilities Of The B Cell And Isolated Lymphoid Follicle-Lie Structures In The Red-Eared Slider, Trachemys Scripta, Marc A. Ashford Jr.
Theses and Dissertations
Management of immunity is crucial for survival in all living organisms. While there is a large amount of research for established model organisms, such as the mouse model, much less is known about reptiles. When compared to immunity in mammals, we discover many differences such as susceptibility to certain pathogens, alteration of immune processes due to environmental temperature, the total absence of certain lymphoid organs contained in mammals, among many others. Despite this, the reptile has shown in many studies that they are worthy systems to study immunity in an evolutionary perspective and recent studies may show that they may …
Age-Structured And Vaccination Models Of Devil Facial Tumor Disease, Christopher D. Bruno, Timothy Comar, Megan O. Powell, Adjo Tameklo
Age-Structured And Vaccination Models Of Devil Facial Tumor Disease, Christopher D. Bruno, Timothy Comar, Megan O. Powell, Adjo Tameklo
Spora: A Journal of Biomathematics
Tasmanian devil populations have been devastated by devil facial tumor disease (DFTD) since its first appearance in 1996. The average lifespan of a devil has decreased from six years to three years. We present an age-structured model to represent how the disease has affected the age and breeding structures of the population. We show that with the recent increase in the breeding of juvenile devils, the overall devil population will increase but not nearly to pre-DFTD levels. The basic reproductive number may be increased with the influx of young breeding devils. In addition, our model shows that the release of …
The Biochemical Assessment Of Two Secreted Acid Phosphatases From Leishmania Tarentolae, Their Response To Electric Fields, Glycosidase Incubation, And / Or Vanadium, Benjamin M. Dorsey
The Biochemical Assessment Of Two Secreted Acid Phosphatases From Leishmania Tarentolae, Their Response To Electric Fields, Glycosidase Incubation, And / Or Vanadium, Benjamin M. Dorsey
Theses and Dissertations
Leishmaniasis, as defined by the Center for Disease Control and Prevention, is a neglected tropical disease with 1.6 million new cases reported each year. However, there is yet to be safe, effective, and affordable treatments provided to those affected by this disease1. Still underappreciated as a potential pharmaceutical targets, especially for cutaneous leishmaniasis infections, are the two isozymes of secreted acid phosphatase (SAP); secreted acid phosphatase 1 (SAP1) and secreted acid phosphatase 2 (SAP2). These enzymes are involved in the survival of the parasite in the sand fly vector, and the prevention of host macrophages from forming parasitophorous vacuole and …
Modeling Vaccination Strategies To Control White-Nose Syndrome In Little Brown Bat Colonies, Eva Cornwell, David Elzinga, Shelby Stowe, Alex Capaldi
Modeling Vaccination Strategies To Control White-Nose Syndrome In Little Brown Bat Colonies, Eva Cornwell, David Elzinga, Shelby Stowe, Alex Capaldi
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Stochastic And Deterministic Multigroup Epidemiology, Jordan Hasler, Chris Chang, Ananya Yammanuru, Lewis Oh, Esther Matthew, Mounisha Kovour
Stochastic And Deterministic Multigroup Epidemiology, Jordan Hasler, Chris Chang, Ananya Yammanuru, Lewis Oh, Esther Matthew, Mounisha Kovour
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
The Kinetics Of Type I Interferons During Influenza A Virus Infection, Margaret A. Myers
The Kinetics Of Type I Interferons During Influenza A Virus Infection, Margaret A. Myers
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Should I Get A Flu Shot? How Well Did This Go Last Year?, Winfried Just, David Gerberry, Ying Xin
Should I Get A Flu Shot? How Well Did This Go Last Year?, Winfried Just, David Gerberry, Ying Xin
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Model Of Dengue Transmission With Wolbachia-Free And Wolbachia-Infected Mosquitoes, Iftikhar Ahmed
A Model Of Dengue Transmission With Wolbachia-Free And Wolbachia-Infected Mosquitoes, Iftikhar Ahmed
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Markov Models Reveal Host Controls Of Within-Host Disease Dynamics, Tara Stewart, Zoi Rapti, Carla E. Cáceres
Markov Models Reveal Host Controls Of Within-Host Disease Dynamics, Tara Stewart, Zoi Rapti, Carla E. Cáceres
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
The Role Of Intermittent Preventive Treatment For Malaria In Saving Lives And Promoting Drug Resistance, Carrie Manore
The Role Of Intermittent Preventive Treatment For Malaria In Saving Lives And Promoting Drug Resistance, Carrie Manore
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling Cross-Species Extrapolation Of Inhalation Anthrax For Risk Assessment Purposes, Megan O. Powell
Modeling Cross-Species Extrapolation Of Inhalation Anthrax For Risk Assessment Purposes, Megan O. Powell
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Vaccination Strategies For Small Worlds, Winfried Just, Hannah L. Callender
Vaccination Strategies For Small Worlds, Winfried Just, Hannah L. Callender
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Inhibitory Effects Of Unique Sulfonamides On Leishmania Tarentolae And Potential Pathway Of Inhibition, Jade M. Katinas
Inhibitory Effects Of Unique Sulfonamides On Leishmania Tarentolae And Potential Pathway Of Inhibition, Jade M. Katinas
Theses and Dissertations
Leishmaniasis is an endemic disease caused by the protozoan parasite Leishmania. Current treatments for the parasite are limited by cost, availability, and drug resistance as the worldwide occurrence of leishmaniasis continues to be more prevalent. Sulfonamides are a class of compounds with medicinal properties that have been used to treat bacterial and parasitic diseases via various pathways. In this study, newly synthesized, unique structural analogs of sulfonamide compounds were assessed for their impact on Leishmania cell viability and potential pathways for inhibition were evaluated. Leishmania tarentolae (ATCC Strain 30143) axenic promastigote cells were grown in BHI medium and treated with …
Bacterially-Based Immune Challenges And Trauma Elicit Terminal Investment In Male Aedes Aegypti, Molly K. Schumacher
Bacterially-Based Immune Challenges And Trauma Elicit Terminal Investment In Male Aedes Aegypti, Molly K. Schumacher
Theses and Dissertations
Investment in life history traits such as immune function and reproduction is constrained by finite available resources. A cost-of-immunity trade-off may occur in response to infection when resources are diverted away from reproductive effort and into an immune response. Alternatively, an infected individual may enhance reproductive effort to maximize terminal reproductive success in response to the survival threat inherent to infection (terminal investment). We measured male Aedes aegypti reproductive behavior following inoculations with: living bacteria; killed bacteria as an immune elicitor; and a sham control. Mating competitiveness relative to naïve males was also determined through a binary mate choice experiment …
Expression, Localization, And Kinetic Characterization Of The Phospholipid Biosynthesis Enzyme Ctp: Phosphocholine Cytidylyltransferase From The Protozoan Parasite Leishmania Major, Justin Daniel Theodore Lange
Expression, Localization, And Kinetic Characterization Of The Phospholipid Biosynthesis Enzyme Ctp: Phosphocholine Cytidylyltransferase From The Protozoan Parasite Leishmania Major, Justin Daniel Theodore Lange
Theses and Dissertations
The eukaryotic parasite Leishmania is the causative agent of the disease leishmaniasis. L. major is the most common of 21 species that causes visceral leishmaniasis in humans, and 30 that cause the same disease in other mammals. Visceral leishmaniasis causes fever, weight loss, and over a short amount of time, multiple organ failure, and has a 100% mortality rate within 2 years. This makes it the second largest parasitic killer in the world behind malaria. Over 90% of the worldâ??s cases of visceral leishmaniasis have been reported in underdeveloped countries of India, Bangladesh, Nepal, Sudan, Ethiopia and Brazil, with 500,000 …