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Full-Text Articles in Other Genetics and Genomics

A Standardized G‐Banded Karyotype For The Raccoon (Procyon Lotor) Compared With The Domestic Cat, Roscoe Stanyon, Francesca Bigoni, Johannes Weinberg, John Hadidian Jan 1993

A Standardized G‐Banded Karyotype For The Raccoon (Procyon Lotor) Compared With The Domestic Cat, Roscoe Stanyon, Francesca Bigoni, Johannes Weinberg, John Hadidian

Genetics Collection

We propose a standardized karyotype for the raccoon (Procyon lotor; 2n = 38, FN 74) and compare it with that of the domestic cat (2n = 38, FN 72). Numerous chromosomes (12) have similar and sometimes identical G-banding and 14 chromosome pairs have remained intact. Other chromosomes apparently differ by Robertsonian translocations and inversions. The conservation of these karyotypes is remarkable considering that the divergence of procyonids and felids predates 50 million years B.P. However, the common diploid number of 38 is not a primitive retention, as sometimes hypothesized. Instead, cats and raccoons converged on this chromosome number by a …


A Family Showing No Evidence Of Linkage Between The Ataxia Telangiectasia Gene And Chromosome, D. Hernandez, C. M. Mcconville, Michael W. Stacy, C. G. Woods, M. M. Brown, P. Shutt, G. Rysiecki, A. M. R. Taylor Jan 1993

A Family Showing No Evidence Of Linkage Between The Ataxia Telangiectasia Gene And Chromosome, D. Hernandez, C. M. Mcconville, Michael W. Stacy, C. G. Woods, M. M. Brown, P. Shutt, G. Rysiecki, A. M. R. Taylor

Bioelectrics Publications

We have studied an inbred family in which two cousins presented with the same clinical features of ataxia telangiectasia (AT). Both patients are still ambulatory at ages 25 and 20. Cellular features of both patients are typical of AT and include increased radiosensitivity and an increased level of spontaneously occurring chromosome aberrations in peripheral blood lymphocytes. Linkage studies and haplotype analysis show no clear evidence that the gene for AT in this family is on chromosome 11q22-23. As previously reported AT families from complementation groups AB, C, and D have all shown linkage to this region of 11q22-23. Our study …